Marianne Hiorth

Professor - Section for Pharmaceutics and Social Pharmacy

Norwegian version of this page

Email marianne.hiorth@farmasi.uio.no

Phone +47 22857905

Room 047C

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Visiting address Sem Sælands vei 3 Farmasibygningen 0371 Oslo

Postal address Postboks 1068 Blindern 0316 Oslo

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Academic Interests

Development and characterization of oral drug delivery systems for treatment of dry mouth and teeth related problems such as caries and erosion. As drug carriers my main interests are polymerbased nanospheres and polymer coated liposomes.

Teaching

Higher education and employment history

Professor, School of Pharmacy, 2013 -

Associate professor, School of Pharmacy, 2006-2013

PhD Candidate, University of Oslo, 2000-2005

Dr.Scient., University of Oslo, 2005

Cand.Pharm., University of Oslo, 1999

Student, Faculty of Mathematics and Natural Sciences, University of Bergen 1992-1994

Cooperation

Professor Ørjan Martinsen, Department of Physics, University of Oslo

Professor Morten Rykke, Professor Alix Vik, Associate professor Lene Hystad Hove and Professor Janicke Liåen Jensen, Faculty of Dentistry, University of Oslo

Professor Natasha Skalko-Basnet, Department of Pharmacy, UiT The Arctic University of Norway

Professor Anna-Lena Kjøniksen, The Faculty of Engineering, Østfold University College, Norway

Associate professor Ellen Hagesæther, Department of Life Sciences and Health, Oslo and Akershus University College of Applied Sciences

Associate professor Jette Jacobsen, Department of Pharmacy, University of Copenhagen, Denmark

Professor Cristina Bonferoni, Dipartimento di Scienze del Farmaco, University of Pavia, Italy

Professor Dr. Francisco Goycoolea, School of Food Science and Nutrition, University of Leeds, UK

Dr. José H. Cifre, Dept. of Physical Chemistry, University of Murcia, Spain

Dr. F. O. de Sousa, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Brazil

Professor Julijana Kristl, Faculty of Pharmacy, University of Ljubljana, Slovenia

Tags: Pharmaceutics

Johnsen, Hennie Marie; Hossaini Nasr, Seyedmehdi; De Luna, Ricardo; Filtvedt, Werner Olav; Sailor, Michael J. & Klaveness, Jo [Show all 7 contributors for this article] (2024). Stable “snow lantern-like” aggregates of silicon nanoparticles suitable as a drug delivery platform. Nanoscale. ISSN 2040-3364. doi: 10.1039/d3nr05655d.
Tzanova, Martina Martin; Larsen, Bjarke Strøm; Birolo, Rebecca; Cignolini, Sara; Tho, Ingunn & Chierotti, Michele R. [Show all 11 contributors for this article] (2024). Shifting the Focus from Dissolution to Permeation: Introducing the Meso-fluidic Chip for Permeability Assessment (MCPA). Journal of Pharmaceutical Sciences. ISSN 0022-3549. doi: 10.1016/j.xphs.2023.12.012. Full text in Research Archive
Johnsen, Hennie Marie; Hiorth, Marianne & Klaveness, Jo (2023). Molecular Hydrogen Therapy—A Review on Clinical Studies and Outcomes. Molecules. ISSN 1431-5157. 28(23). doi: 10.3390/molecules28237785. Full text in Research Archive
Ellefsen, Christiane Færestrand; Lindstad, Linda; Klau, Leesa Jane; Aachmann, Finn Lillelund; Hiorth, Marianne & Samuelsen, Anne Berit C. (2023). Investigation of the structural and immunomodulatory properties of alkali-soluble β-glucans from Pleurotus eryngii fruiting bodies. Carbohydrate Polymers. ISSN 0144-8617. 322. doi: 10.1016/j.carbpol.2023.121367. Full text in Research Archive
Frigaard, Julie Mari; Jensen, Janicke Liaaen; Galtung, Hilde & Hiorth, Marianne (2023). Stability and cytotoxicity of biopolymer-coated liposomes for use in the oral cavity. International Journal of Pharmaceutics. ISSN 0378-5173. 645. doi: 10.1016/j.ijpharm.2023.123407. Full text in Research Archive
Tzanova, Martina Martin; Nguyen, Lisa; Moretti, Federica; Grassi, Mario; Magnano, Greta Camilla & Voinovich, Dario [Show all 9 contributors for this article] (2023). Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 189. doi: 10.1016/j.ejps.2023.106559. Full text in Research Archive
Nguyen, Sanko & Hiorth, Marianne (2023). Intraorale formuleringer - moderne produkter og potensialet i fremtidige nanobaserte formuleringer. Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 5, p. 22–27.
Ellefsen, Christiane Færestrand; Struzek, Anna-Maria; Scherliess, Regina; Hiorth, Marianne & Samuelsen, Anne Berit C. (2023). Preparation of Albatrellus ovinus β-Glucan Microparticles with Dectin-1a Binding Properties. ACS Applied Bio Materials (AABM). ISSN 2576-6422. 6(5), p. 1863–1872. doi: 10.1021/acsabm.3c00071. Full text in Research Archive
Hiorth, Marianne; Mihailovic, Ljubica; Adamczak, Malgorzata Iwona; Goycoolea, Francisco M. & Sarkar, Anwesha (2023). Lubricating Performance of Polymer-Coated Liposomes. Biotribology. ISSN 2352-5738. 35-36. doi: 10.1016/j.biotri.2023.100239. Full text in Research Archive
Johnsen, Hennie Marie; Filtvedt, Werner Olav; Hiorth, Marianne & Klaveness, Jo (2022). Silicon nanoparticles for oral administration of molecular hydrogen. International Journal of Pharmaceutics. ISSN 0378-5173. 629. doi: 10.1016/j.ijpharm.2022.122371. Full text in Research Archive
Azumah, Joseph; Smistad, Gro & Hiorth, Marianne (2022). Preparation of stable polymer-liposome complexes by a novel approach employing a one-pot method. Colloids and Surfaces A: Physicochemical and Engineering Aspects. ISSN 0927-7757. 653. doi: 10.1016/j.colsurfa.2022.129924. Full text in Research Archive Show summary
The purpose of this study was to prepare stable polymer-liposome complexes using a new, improved one-pot method. Complexes prepared by the conventional method were used as reference. The one-pot method combines the vesicle formation and complexation with the polymer in a single step allowing for fewer steps compared to the conventional thin-film method followed by coating. This has the possibility of complexing the polymer on the surface and within the aqueous core of the liposomes. Soya phosphatidylcholine (SoyPC) in combination with different amounts of either dioleoyl trimethylammoniumpropane (DOTAP, positively charged) or egg phosphatidylglycerol (Egg PG, negatively charged) were complexed with alginate or chitosan, respectively. All the alginate-liposome complexes were larger compared to the naked liposomes and the zeta potential changed from positive to negative after complexation with the polymer. Polydispersity index (PDI) analysis showed narrow size distributions implying homogenous populations. The best stability was obtained by employing 20 mol% DOTAP in the membrane. This formulation was stable during the whole four months period when the stability test was performed. The chitosan-liposome complexes were generally difficult to extrude and were larger than the alginate-liposome complexes due to the need for a larger pore size in the membrane during extrusion. Based on these results, the one-pot method can be used for preparing stable alginate-liposome complexes. For the chitosan-liposome complexes alternative methods for size reduction should be investigated.
Tzanova, Martina Martin; Moretti, Federica; Grassi, Gabriele; Stein, Paul; Hiorth, Marianne & Abrami, Michela [Show all 8 contributors for this article] (2022). Modelling drug diffusion through unstirred water layers allows real-time quantification of free/loaded drug fractions and release kinetics from colloidal-based formulations. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 178, p. 168–178. doi: 10.1016/j.ejpb.2022.08.009. Full text in Research Archive
Frigaard, Julie Mari; Jensen, Janicke Liaaen; Galtung, Hilde & Hiorth, Marianne (2022). The Potential of Chitosan in Nanomedicine: An Overview of the Cytotoxicity of Chitosan Based Nanoparticles. Frontiers in Pharmacology. ISSN 1663-9812. 13. doi: 10.3389/fphar.2022.880377. Full text in Research Archive
Tzanova, Martina Martin; Randelov, Elizabeta; Stein, Paul C.; Hiorth, Marianne & Di Cagno, Massimiliano Pio (2021). Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay. International Journal of Pharmaceutics. ISSN 0378-5173. 608. doi: 10.1016/j.ijpharm.2021.121116. Full text in Research Archive
Hagesæther, Ellen; Adamczak, Malgorzata Iwona; Hiorth, Marianne & Tho, Ingunn (2020). Characterization of Bioadhesion, Mucin‐interactions and Mucosal Permeability of Pharmaceutical Nano‐ and Microsystems. In Peltonen, Leena (Eds.), Characterization of Pharmaceutical Nano and Microsystems. John Wiley & Sons. ISSN 9781119414018. p. 171–205. doi: https:/doi.org/10.1002/9781119414018.ch5.
Che, Loan Trinh; Hiorth, Marianne; Hoogenboom, Richard & Kjøniksen, Anna-Lena (2020). Complex temperature and concentration dependent self-assembly of poly(2-oxazoline) block copolymers. Polymers. ISSN 2073-4360. 12:1495(7), p. 1–16. doi: 10.3390/polym12071495. Full text in Research Archive
Tandberg, Julia Isabel; Lagos Rojas, Leidy Ximena; Ropstad, Erik; Smistad, Gro; Hiorth, Marianne & Winther-Larsen, Hanne Cecilie (2018). The use of chitosan-coated membrane vesicles for immunization against salmonid rickettsial septicemia in an adult zebrafish model. Zebrafish. ISSN 1545-8547. 15(4), p. 372–381. doi: 10.1089/zeb.2017.1556.
Cao, Vinh Duy; Salas Bringas, Carlos; Schüller, Reidar Barfod; Szczotok-Piechaczek, Anna Maria; Hiorth, Marianne & Carmona, Manuel [Show all 8 contributors for this article] (2018). Rheological and thermal properties of suspensions of microcapsules containing phase change materials. Colloid and Polymer Science. ISSN 0303-402X. 296(5), p. 981–988. doi: 10.1007/s00396-018-4316-9. Full text in Research Archive
Smistad, Gro; Nyström, Bo; Zhu, Kaizheng; Grønvold, Marte; Røv-Johnsen, Anne & Hiorth, Marianne (2017). Liposomes coated with hydrophobically modified hydroxyethyl cellulose: Influence of hydrophobic chain length and degree of modification. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 156, p. 79–86. doi: 10.1016/j.colsurfb.2017.04.061. Full text in Research Archive
Hiorth, Marianne (2017). Improved Drug Delivery Systems for Preventing Dental Caries. Current Drug Delivery. ISSN 1567-2018. 14(4), p. 446–448. doi: 10.2174/1567201813666161014091339.
Nguyen, Sanko; Escudero, Carlos; Sediqi, Nadia; Smistad, Gro & Hiorth, Marianne (2017). Fluoride loaded polymeric nanoparticles for dental delivery. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 104, p. 326–334. doi: 10.1016/j.ejps.2017.04.004. Full text in Research Archive
Adamczak, Malgorzata Iwona; Martinsen, Ørjan Grøttem; Smistad, Gro & Hiorth, Marianne (2017). Polymer coated mucoadhesive liposomes intended for the management of xerostomia. International Journal of Pharmaceutics. ISSN 0378-5173. 527(1-2), p. 72–78. doi: 10.1016/j.ijpharm.2017.05.032. Full text in Research Archive
Mackie, Alan R.; Goycoolea, Francisco M.; Menchicchi, Bianca; Caramella, Carla Marcella; Saporito, Francesca & Lee, Seunghwan [Show all 13 contributors for this article] (2017). Innovative Methods and Applications in Mucoadhesion Research. Macromolecular Bioscience. ISSN 1616-5187. 17:1600534(8), p. 1–32. doi: 10.1002/mabi.201600534.
Pistone, Sara; Rykke, Morten; Smistad, Gro & Hiorth, Marianne (2017). Polysaccharide-coated liposomal formulations for dental targeting. International Journal of Pharmaceutics. ISSN 0378-5173. 516(1-2), p. 106–115. doi: 10.1016/j.ijpharm.2016.11.028. Full text in Research Archive
Pistone, Sara; Goycoolea, Francisco M.; Young, Alix; Smistad, Gro & Hiorth, Marianne (2017). Formulation of polysaccharide-based nanoparticles for local administration into the oral cavity. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 96, p. 381–389. doi: 10.1016/j.ejps.2016.10.012. Full text in Research Archive
Klemetsrud, Therese; Kjøniksen, Anna-Lena; Hiorth, Marianne; Jacobsen, Jette & Smistad, Gro (2016). Polymer coated liposomes for use in the oral cavity – a study of the in vitro toxicity, effect on cell permeability and interaction with mucin. Journal of liposome research. ISSN 0898-2104. 28(1), p. 62–73. doi: 10.1080/08982104.2016.1255640.
Mirtic, Janja; Kogej, Ksenija; Baumgartner, Sasa; Smistad, Gro; Kristl, Julijana & Hiorth, Marianne (2016). Development of Cetylpyridinium-Alginate Nanoparticles: A Binding and Formulation Study. International Journal of Pharmaceutics. ISSN 0378-5173. 511(2), p. 774–784. doi: 10.1016/j.ijpharm.2016.07.065.
Pistone, Sara; Qoragllu, Dafina; Smistad, Gro & Hiorth, Marianne (2016). Multivariate analysis for the optimization of polysaccharide-based nanoparticles prepared by self-assembly . Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 146, p. 136–143. doi: 10.1016/j.colsurfb.2016.05.055.
Adamczak, Malgorzata Iwona; Martinsen, Ørjan Grøttem; Smistad, Gro & Hiorth, Marianne (2016). Water sorption properties of HM-pectin and liposomes intended to alleviate dry mouth. International Journal of Pharmaceutics. ISSN 0378-5173. 506(1-2), p. 201–206. doi: 10.1016/j.ijpharm.2016.04.050. Full text in Research Archive
Nguyen, Sanko; Smistad, Gro; Rykke, Morten & Hiorth, Marianne (2016). Nanoparticulate Systems for Dental Drug Delivery. In Arias, Jose L. (Eds.), Nanotechnology and Drug Delivery - volume II: Nano-Engineering Strategies and Nanomedicines Against Severe Diseases.. CRC Press. ISSN 9781482262711. p. 52–74. doi: 10.1201/b19976-3.
Adamczak, Malgorzata Iwona; Hagesæther, Ellen; Smistad, Gro & Hiorth, Marianne (2016). An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells. International Journal of Pharmaceutics. ISSN 0378-5173. 498(1-2), p. 225–233. doi: 10.1016/j.ijpharm.2015.12.030. Full text in Research Archive
Nguyen, Sanko; Adamczak, Malgorzata Iwona; Hiorth, Marianne; Smistad, Gro & Kopperud, Hilde Beate M. (2015). Interactions of liposomes with dental restorative materials. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 136, p. 744–751. doi: 10.1016/j.colsurfb.2015.10.024.
Pistone, Sara; Qoragllu, Dafina; Smistad, Gro & Hiorth, Marianne (2015). Formulation and preparation of stable cross-linked alginate-zinc nanoparticles in the presence of a monovalent salt. Soft Matter. ISSN 1744-683X. 11(28), p. 5765–5774. doi: 10.1039/c5sm00700c.
Nguyen, Sanko & Hiorth, Marianne (2015). Advanced drug delivery systems for local treatment of the oral cavity. Therapeutic delivery. ISSN 2041-5990. 6(5), p. 197–210. doi: 10.4155/tde.15.5.
Klemetsrud, Therese; Hiorth, Marianne; Smistad, Gro & Kjøniksen, Anna-Lena (2015). Characterization of temperature induced changes in liposomes coated with poly(N-isopropylacrylamide-co-methacrylic acid). Journal of Colloid and Interface Science. ISSN 0021-9797. 450, p. 7–16. doi: 10.1016/j.jcis.2015.03.005.
Meland, Hilde-Gunn; Røv-Johnsen, Anne; Smistad, Gro & Hiorth, Marianne (2014). Studies on surface coating of phospholipid vesicles with a non-ionic polymer. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 114, p. 45–52. doi: 10.1016/j.colsurfb.2013.09.054.
Hiorth, Marianne ; Nilsen, Susanne & Tho, Ingunn (2014). Bioadhesive Mini-Tablets for Vaginal Drug Delivery. Pharmaceutics. ISSN 1999-4923. 6(3), p. 494–511. doi: 10.3390/pharmaceutics6030494. Full text in Research Archive
Klemetsrud, Therese; Jonassen, Helene; Hiorth, Marianne ; Kjøniksen, Anna-Lena & Smistad, Gro (2013). Studies on pectin-coated liposomes and their interaction with mucin. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 103, p. 158–165. doi: 10.1016/j.colsurfb.2012.10.012.
Hiorth, Marianne ; Liereng, Linda; Reinertsen Selmer, Reidun & Tho, Ingunn (2013). Formulation of bioadhesive hexylaminolevulinate pellets intended for photodynamic therapy in the treatment of cervical cancer. International Journal of Pharmaceutics. ISSN 0378-5173. 441(1-2), p. 544–554. doi: 10.1016/j.ijpharm.2012.10.046.
Nguyen, Sanko; Hiorth, Marianne ; Rykke, Morten & Smistad, Gro (2013). Polymer coated liposomes for dental drug delivery - Interactions with parotid saliva and dental enamel. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 50(1), p. 78–85. doi: 10.1016/j.ejps.2013.03.004.
Jonassen, Helene; Treves, Alessandro; Kjøniksen, Anna-Lena; Smistad, Gro & Hiorth, Marianne (2013). Preparation of Ionically Cross-Linked Pectin Nanoparticles in the Presence of Chlorides of Divalent and Monovalent Cations. Biomacromolecules. ISSN 1525-7797. 14(10), p. 3523–3531. doi: 10.1021/bm4008474.
Alund, Siv Jorunn; Smistad, Gro & Hiorth, Marianne (2013). A multivariate analysis investigating different factors important for the interaction between liposomes and pectin. Colloids and Surfaces A: Physicochemical and Engineering Aspects. ISSN 0927-7757. 420, p. 1–9. doi: 10.1016/j.colsurfa.2012.11.079.
Smistad, Gro; Bøyum, Silje; Alund, Siv Jorunn; Samuelsen, Anne Berit C. & Hiorth, Marianne (2012). The potential of pectin as a stabilizer for liposomal drug delivery systems. Carbohydrate Polymers. ISSN 0144-8617. 90(3), p. 1337–1344. doi: 10.1016/j.carbpol.2012.07.002.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2012). Stability of Chitosan Nanoparticles Cross-Linked with Tripolyphosphate. Biomacromolecules. ISSN 1525-7797. 13(11), p. 3747–3756. doi: 10.1021/bm301207a.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2012). Effects of ionic strength on the size and compactness of chitosan nanoparticles. Colloid and Polymer Science. ISSN 0303-402X. 290(10), p. 919–929. doi: 10.1007/s00396-012-2604-3.
Nguyen, Sanko; Alund, Siv Jorunn; Hiorth, Marianne ; Kjøniksen, Anna-Lena & Smistad, Gro (2011). Studies on pectin coating of liposomes for drug delivery. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 88(2), p. 664–673. doi: 10.1016/j.colsurfb.2011.07.058.
Nguyen, Sanko; Hiorth, Marianne ; Rykke, Morten & Smistad, Gro (2011). The potential of liposomes as dental drug delivery systems. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 77(1), p. 75–83. doi: 10.1016/j.ejpb.2010.09.010.
Hiorth, Marianne (2010). Oral administrasjon av legemidler til tykktarmen :. Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 118(11), p. 28–31.
Hiorth, Marianne ; Skøien, Terje & Sande, Sverre Arne (2010). Immersion coating of pellet cores consisting of chitosan and calcium intended for colon drug delivery. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 75(2), p. 245–253. doi: 10.1016/j.ejpb.2010.02.012.
Nguyen, Sanko; Solheim, Lee; Bye, Ragnar; Rykke, Morten; Hiorth, Marianne & Smistad, Gro (2010). The influence of liposomal formulation factors on the interactions between liposomes and hydroxyapatite. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 76(1), p. 354–361. doi: 10.1016/j.colsurfb.2009.11.020.
Hagesæther, Ellen; Hiorth, Marianne & Sande, Sverre Arne (2009). Mucoadhesion and drug permeability of free mixed films of pectin and chitosan: An in vitro and ex vivo study. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 71(2), p. 325–331. doi: 10.1016/j.ejpb.2008.09.002.

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Ellefsen, Christiane Færestrand; Struzek, Anna-Maria; Scherliess, Regina; Hiorth, Marianne & Samuelsen, Anne Berit C. (2022). Mushroom β-glucan microparticles with immuno-activating potential.
Frigaard, Julie Mari; Jensen, Janicke Liaaen; Galtung, Hilde & Hiorth, Marianne (2021). Development of a Liposomal Dry Mouth Product for Long-term Relief.
Ellefsen, Christiane Færestrand; Hiorth, Marianne & Samuelsen, Anne Berit C. (2021). Preparation of fungal β-glucan particles by acid precipitation.
Azumah, Joseph; Smistad, Gro; Martinsen, Ørjan Grøttem & Hiorth, Marianne (2019). Development of alginate coated liposomes with potential of being used in treatment of dry mouth.
Azumah, Joseph; Hiorth, Marianne; Smistad, Gro & Martinsen, Ørjan Grøttem (2019). Development of alginate and chitosan coated liposomes intended to use in the treatment of xerostomia.
Azumah, Joseph; Hiorth, Marianne; Smistad, Gro & Martinsen, Ørjan Grøttem (2019). Alginate and chitosan coated liposomes intended for treatment of dry mouth.
Hiorth, Marianne (2019). The potential of polymer-coated liposomes as a salivary substitute.
Hiorth, Marianne; Azumah, Joseph & Smistad, Gro (2019). The potential of polymer-coated liposomes for dental care .
Hiorth, Marianne (2018). The potential of nanoparticles in the combat against dry mouth.
Hiorth, Marianne; Adamczak, Malgorzata Iwona; Gonzalez Espinosa, Yadira; Goycoolea, Francisco M. & Sarkar, Anwesha (2018). Lubricating properties of polymer coated liposomes.
Hiorth, Marianne (2017). Development of polymer based nanospheres and polymer coated liposomes for drug delivery to the oral cavity .
Hiorth, Marianne (2017). The NanoTeeth Project.
Hiorth, Marianne (2017). Med nanopartikler inn i fremtidens tannbehandling.
Hiorth, Marianne (2017). The potential of nanoparticles as a salivary substitute.
Nguyen, Sanko; Adamczak, Malgorzata Iwona; Hiorth, Marianne; Smistad, Gro & Kopperud, Hilde Beate M. (2016). Liposome adsorption to restorative materials. Dental Materials. ISSN 0109-5641. 32. doi: 10.1016/j.dental.2016.08.049.
Hiorth, Marianne (2016). Nanoparticles – The future for better oral health?
Pistone, Sara; Goycoolea, Francisco; Smistad, Gro & Hiorth, Marianne (2016). Polymer coated liposomes intended for protective functions of the teeth.
Hiorth, Marianne (2016). Can locally administered nanoparticles revolutionize the treatment of the oral cavity?
Hiorth, Marianne; Pistone, Sara; Smistad, Gro & Goycoolea, Francisco (2016). Polymer-coated liposomes for protective functions of the teeth.
Nguyen, Sanko; Kur, Malgorzata Anna; Hiorth, Marianne & Smistad, Gro (2016). Formulation of pH-sensitive liposomes for caries prophylaxis.
Hiorth, Marianne (2016). Nanotechnology for drug targeting/site specific drug delivery.
Hiorth, Marianne (2016). Null hull.
Nguyen, Sanko; Sediqi, Nadia; Smistad, Gro & Hiorth, Marianne (2016). Preparation and characterization of fluoride loaded polymeric nanoparticles for dental delivery .
Hiorth, Marianne (2015). Null hull med nanoteknologi.
Pistone, Sara; Qoragllu, Dafina; Smistad, Gro & Hiorth, Marianne (2015). Development of an alternative method for the preparation of alginate nanoparticles by self-assembly .
Pistone, Sara; Qoragllu, Dafina; Smistad, Gro & Hiorth, Marianne (2015). Development of alginate nanoparticles as drug carriers for teeth ailments .
Che, Loan Trinh; Kjøniksen, Anna-Lena; Lambermont-Thijs, Hanneke M. L.; Hoogenboom, Richard; Schubert, Ulrich S. & Hiorth, Marianne (2015). Complex Temperature and Concentration – dependent Self-assembly of Poly(2-oxazoline) Block Copolymers.
Nguyen, Sanko; Pistone, Sara; Claudio, Cavalli; Smistad, Gro & Hiorth, Marianne (2015). Effect of ionic strength on the formation of fluoride loaded pectin nanoparticles for dental delivery.
Hiorth, Marianne (2015). Jakten på fremtidens nanopartikler.
Hiorth, Marianne (2015). Jakten på fremtidens nanomedisiner.
Hiorth, Marianne (2015). The Magic bullet - Nanopartikler i fremtidens legemidler.
Hiorth, Marianne (2015). Bruk av nanopartikler i (fremtidens) legemidler .
Hiorth, Marianne (2015). Advanced drug delivery systems based on bioadhesion/mucoadhesion for local treatment of the oral cavity.
Hiorth, Marianne; Adamczak, Malgorzata Iwona; Nguyen, Sanko; Pistone, Sara; Sediqi, Nadia & Smistad, Gro (2015). Development of chitosan based nanoparticles for drug delivery to the teeth.
Adamczak, Malgorzata Iwona; Hagesæther, Ellen; Hiorth, Marianne; Martinsen, Ørjan Grøttem; Sediqi, Nadia & Smistad, Gro (2015). Chitosan-based nanoparticles and chitosan-coated liposomes for drug delivery to the oral cavity.
Pistone, Sara; Cavalli, Claudio; Smistad, Gro & Hiorth, Marianne (2014). Formulation of nanoparticles for protective functions of the teeth.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2013). Polysaccharide-based Nanoparticles as a Drug Delivery System - Preparation and Physico-chemial Characterization.
Klemetsrud, Therese; Hiorth, Marianne ; Kjøniksen, Anna-Lena & Smistad, Gro (2013). Liposomal complexes that changes around body temperature.
Yip, Wai Lam; Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2013). Preparation of chitosan nanoparticles – a multivariate approach.
Klemetsrud, Therese; Kjøniksen, Anna-Lena; Hiorth, Marianne & Smistad, Gro (2012). Studies on pectin coated liposomes and their interaction with mucin.
Kjøniksen, Anna-Lena; Jonassen, Helene & Hiorth, Marianne (2012). Chitosan Nanoparticles for Drug Delivery Applications.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2012). Polysakkarid-baserte nanopartikler som legemiddelform.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2012). Compactness of chitosan nanoparticles and implications in drug delivery.
Klemetsrud, Therese; Kjøniksen, Anna-Lena; Hiorth, Marianne & Smistad, Gro (2011). In vitro characterization of potential mucoadhesive properties of nanoparticles.
Jonassen, Helene; Kjøniksen, Anna-Lena & Hiorth, Marianne (2011). Adjustment of solvent salinity in the preparation of chitosan nanoparticles – effects on important particle characteristics.
Nguyen, Sanko; Hiorth, Marianne ; Rykke, Morten & Smistad, Gro (2010). Liposomes - interactions with salivary constituents.
Nguyen, Sanko H.; Rykke, Morten; Hiorth, Marianne & Smistad, Gro (2009). The influence of formulation factors on the interactions between liposomes and hydroxyapatite.
Hiorth, Marianne ; Skøien, Terje & Sande, Sverre Arne (2008). Immersion coating of two different types of pellets intended for colon drug delivery.
Hiorth, Marianne ; Skøien, Terje & Sande, Sverre Arne (2008). Immersion coating of two different types of pellets intended for colon drug delivery.

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Published Nov. 3, 2010 3:38 PM - Last modified June 21, 2022 2:38 PM

Projects

Fungal beta-glucan particles

Research groups

Site-specific Drug Delivery (SiteDel)