Gaute Tomas Einevoll

• Hagen, Espen; Chambers, Anna; Einevoll, Gaute; Pettersen, Klas Henning; Enger, Rune & Stasik, Alexander Johannes (2021). RippleNet: a Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection. Neuroinformatics. ISSN 1539-2791. 19, s. 493–514. doi: 10.1007/s12021-020-09496-2. Fulltekst i vitenarkiv Vis sammendrag

  Hippocampal sharp wave ripples (SPW-R) have been identified as key bio-markers of important brain functions such as memory consolidation and decision making. Understanding their underlying mechanisms in healthy and pathological brain function and behaviour rely on accurate SPW-R detection. In this multidisciplinary study, we propose a novel, self-improving artificial intelligence (AI) detection method in the form of deep Recurrent Neural Networks (RNN) with Long Short-Term memory (LSTM) layers that can learn features of SPW-R events from raw, labeled input data. The approach contrasts conventional routines that typically relies on hand-crafted, heuristic feature extraction and often laborious manual curation. The algorithm is trained using supervised learning on hand-curated data sets with SPW-R events obtained under controlled conditions. The input to the algorithm is the local field potential (LFP), the low-frequency part of extracellularly recorded electric potentials from the CA1 region of the hippocampus. Its output predictions can be interpreted as time-varying probabilities of SPW-R events for the duration of the inputs. A simple thresholding applied to the output probabilities is found to identify times of SPW-R events with high precision. The non-causal, or bidirectional variant of the proposed algorithm demonstrates consistently better accuracy compared to the causal, or unidirectional counterpart. Reference implementations of the algorithm, named ‘RippleNet’, are open source, freely available, and implemented using a common open-source framework for neural networks (tensorflow.keras) and can be easily incorporated into existing data analysis workflows for processing experimental data.

• Puppo, Francesca; Sadegh, Sanaz; Trujillo, Cleber A.; Thunemann, Martin; Campbell, Evan P. & Vandenberghe, Matthieu [Vis alle 17 forfattere av denne artikkelen] (2021). All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors. Frontiers in Cellular Neuroscience. ISSN 1662-5102. 15. doi: 10.3389/fncel.2021.671549. Fulltekst i vitenarkiv
• Martínez-Cañada, Pablo; Ness, Torbjørn V; Einevoll, Gaute; Fellin, Tommaso & Panzeri, Stefano (2021). Computation of the electroencephalogram (EEG) from network models of point neurons. PLoS Computational Biology. ISSN 1553-734X. 17(4). doi: 10.1371/JOURNAL.PCBI.1008893. Fulltekst i vitenarkiv
• Born, Gregory; Schneider-Soupiadis, Felix A.; Erisken, Sinem; Vaiceliunaite, Agne; Lao, Chu Lan & Mobarhan, Milad [Vis alle 9 forfattere av denne artikkelen] (2021). Corticothalamic feedback sculpts visual spatial integration in mouse thalamus. Nature Neuroscience. ISSN 1097-6256. doi: 10.1038/s41593-021-00943-0.
• Næss, Solveig; Halnes, Geir; Hagen, Espen; Hagler, Donald J.; Dale, Anders M. & Einevoll, Gaute [Vis alle 7 forfattere av denne artikkelen] (2021). Biophysically detailed forward modeling of the neural origin of EEG and MEG signals. NeuroImage. ISSN 1053-8119. 225. doi: 10.1016/j.neuroimage.2020.117467. Fulltekst i vitenarkiv
• Sætra, Marte Julie; Einevoll, Gaute & Halnes, Geir (2021). An electrodiffusive neuron-extracellular-glia model for exploring the genesis of slow potentials in the brain. PLoS Computational Biology. ISSN 1553-734X. doi: 10.1371/journal.pcbi.1008143.
• Valstad, Mathias; Roelfs, Daniël; Slapø, Nora B.; Timpe, Clara M. F.; Rai, Ahsan & Matziorinis, Anna Maria [Vis alle 24 forfattere av denne artikkelen] (2021). Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder. Schizophrenia Bulletin. ISSN 0586-7614. 47(6), s. 1751–1760. doi: 10.1093/schbul/sbab049.
• Buccino, Alessio Paolo & Einevoll, Gaute (2020). MEArec: A fast and customizable testbench simulator for ground-truth extracellular spiking activity. Neuroinformatics. ISSN 1539-2791. 19, s. 185–204. doi: 10.1007/s12021-020-09467-7. Fulltekst i vitenarkiv
• Næss, Solveig; Halnes, Geir; Hagen, Espen; Hagler, Donald J.; Dale, Anders M. & Einevoll, Gaute [Vis alle 7 forfattere av denne artikkelen] (2020). Biophysical modeling of the neural origin of EEG and MEG signals. BioRxiv. ISSN 0362-4331. doi: 10.1101/2020.07.01.181875.
• Ness, Torbjørn Vefferstad; Halnes, Geir; Næss, Solveig; Pettersen, Klas Henning & Einevoll, Gaute (2020). Computing extracellular electric potentials from neuronal simulations. arXiv.org. ISSN 2331-8422.
• Sætra, Marte Julie; Einevoll, Gaute & Halnes, Geir (2020). An electrodiffusive, ion conserving Pinsky-Rinzel model with homeostatic mechanisms. PLoS Computational Biology. ISSN 1553-734X. 16(4), s. 1–36. doi: 10.1371/journal.pcbi.1007661. Fulltekst i vitenarkiv
• Geddes, Justen; Einevoll, Gaute; Acar, Evrim & Stasik, Alexander Johannes (2020). Multi-Linear Population Analysis (MLPA) of LFP Data Using Tensor Decompositions. Frontiers in Applied Mathematics and Statistics. ISSN 2297-4687. doi: 10.3389/fams.2020.00041. Fulltekst i vitenarkiv
• Valstad, Mathias; Moberget, Torgeir; Roelfs, Daniël Thomas Heimen; Slapø, Nora Berz; Timpe, Clara Marie Fides & Beck, Dani [Vis alle 18 forfattere av denne artikkelen] (2020). Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals. NeuroImage. ISSN 1053-8119. doi: 10.1016/j.neuroimage.2020.117302. Fulltekst i vitenarkiv
• Dai, Kael; Gratiy, Sergey L.; Billeh, Yazan; Xu, Richard; Cai, Binghuang & Cain, Nicholas [Vis alle 12 forfattere av denne artikkelen] (2020). Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits. PLoS Computational Biology. ISSN 1553-734X. 16(11). doi: 10.1371/journal.pcbi.1008386. Fulltekst i vitenarkiv
• Skaar, Jan-Eirik Welle; Stasik, Alexander Johannes; Hagen, Espen; Ness, Torbjørn V & Einevoll, Gaute (2020). Estimation of neural network model parameters from local field potentials (LFPs). PLoS Computational Biology. ISSN 1553-734X. 16(3). doi: 10.1371/journal.pcbi.1007725. Fulltekst i vitenarkiv
• Ellingsrud, Ada Johanne; Solbrå, Andreas Våvang; Einevoll, Gaute; Halnes, Geir & Rognes, Marie Elisabeth (2020). Finite element simulation of ionic electrodiffusion in cellular geometries. Frontiers in Neuroinformatics. ISSN 1662-5196. 14, s. 1–18. doi: 10.3389/fninf.2020.00011. Fulltekst i vitenarkiv
• Sætra, Marte Julie; Solbrå, Andreas Våvang; Devor, Anna; Sakadžić, Sava; Dale, Anders M. & Einevoll, Gaute (2020). Spatially Resolved Estimation of Metabolic Oxygen Consumption From Optical Measurements in Cortex. Neurophotonics. ISSN 2329-423X. 7(3). doi: 10.1117/1.NPh.7.3.035005. Fulltekst i vitenarkiv
• Mäki-Marttunen, Tuomo; Iannella, Nicolangelo Libero; Edwards, Andrew; Einevoll, Gaute & Blackwell, Kim T. (2020). A unified computational model for cortical post-synaptic plasticity. eLIFE. ISSN 2050-084X. 9, s. 1–37. doi: 10.7554/eLife.55714. Fulltekst i vitenarkiv
• Hagen, Espen; Chambers, Anna; Einevoll, Gaute; Pettersen, Klas Henning; Enger, Rune & Stasik, Alexander Johannes (2020). RippleNet: A Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection. bioRxiv - the preprint server for biology. doi: 10.1101/2020.05.11.087874. Fulltekst i vitenarkiv Vis sammendrag

  Hippocampal sharp wave ripples (SPW-R) have been identified as key bio-markers of important brain functions such as memory consolidation and decision making. SPW-R detection typically relies on hand-crafted feature extraction, and laborious manual curation is often required. In this multidisciplinary study, we propose a novel, self-improving artificial intelligence (AI) method in the form of deep Recurrent Neural Networks (RNN) with Long Short-Term memory (LSTM) layers that can learn features of SPW-R events from raw, labeled input data. The algorithm is trained using supervised learning on hand-curated data sets with SPW-R events. The input to the algorithm is the local field potential (LFP), the low-frequency part of extracellularly recorded electric potentials from the CA1 region of the hippocampus. The output prediction can be interpreted as the time-varying probability of SPW-R events for the duration of the input. A simple thresholding applied to the output probabilities is found to identify times of events with high precision. The reference implementation of the algorithm, named ‘RippleNet’, is open source, freely available, and implemented using a common open-source framework for neural networks (tensorflow.keras) and can be easily incorporated into existing data analysis workflows for processing experimental data.

• Tennøe, Simen; Hodne, Kjetil; Haug, Trude; Weltzien, Finn-Arne; Einevoll, Gaute & Halnes, Geir (2019). [Re] Fast-Activating Voltage- and Calcium-Dependent Potassium (BK) Conductance Promotes Bursting in Pituitary Cells: A Dynamic Clamp Study. ReScience. ISSN 2430-3658. 5(1). doi: 10.5281/zenodo.2611252. Fulltekst i vitenarkiv

Se alle arbeider i Cristin

• Bjorå, Charlotte Sletten; Einevoll, Gaute; Ellingsen-Dalskau, Kristian & Jemterud, Torkild (2021). Abels tårn. [Radio]. NRK P2.
• Einevoll, Gaute & Røyne, Anja (2020). Om løsninger på klimakrisen. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Grøn, Øyvind (2020). Om Einstein og resten av fysikken hans. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute; Tunstad, Erik & Riiser-Larsen, Vibeke (2020). Om neandertalerne. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Grødeland, Gunnveig (2020). Om vaksiner, spesielt koronavaksiner. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute; Bjaalie, Jan G. & Plesser, Hans Ekkehard (2020). Om hjerneforskning og Human Brain Project . [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Grøn, Øyvind (2020). Om Einstein og relativitetsteoriene hans. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Støstad, Hanna Nyborg (2020). Om evolusjonsteorien og naturens mangfold. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & McFadden, Johnjoe (2020). On quantum biology. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Carroll, Sean M (2020). On the physics world view and the interpretation of quantum mechanics. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Raklev, Are (2020). Om partikkelfysikk og jakten på Higgs-bosonet. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Nyborg, Karine (2020). Om klimaøkonomi. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Egeland, Kjølv (2020). Om faren for atomkrig. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Elgarøy, Øystein (2020). Om universet og Big Bang teorien. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Lönn-Stensrud, Jessica (2020). Om bakterier. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Samset, Bjørn Hallvard (2020). Om klimafysikk. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Østby, Hilde (2020). Om kreativitet. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Sejnowski, Terrence J. (2020). On AI and the underlying algorithms . [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Newth, Eirik (2020). Om romfart. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute & Rose, Sunniva (2020). Om kjernekraft og forskningsformiding. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute; Samset, Bjørn Hallvard; Sverdrup-Thygeson, Anne; Svihus, Birger; Østby, Hilde & Røyne, Anja [Vis alle 7 forfattere av denne artikkelen] (2020). Om å gi alle jordas mennesker gode liv uten å ødelegge miljøet. [Internett]. Podcast: Vett og vitenskap med Gaute Einevoll.
• Einevoll, Gaute (2020). Towards multipurpose biophysics-based mathematical models of cortical circuits.
• Einevoll, Gaute (2020). Towards multipurpose biophysics-based mathematical models of cortical circuits.
• Einevoll, Gaute (2020). Towards multipurpose biophysics-based mathematical models of cortical circuits.
• Einevoll, Gaute (2020). Deltagelse i UNGFORSK,Vitenparken/NMBU (virtual).
• Einevoll, Gaute (2020). Kan du tenke deg tynn? [Internett]. forskning.no.
• Einevoll, Gaute (2020). Digital brains are key in understanding how the human brain works, and how it can be fixed when broken. [Internett]. Science Norway.
• Einevoll, Gaute (2020). Nei, det er ingen krise i fysikken. [Internett]. forskning.no.
• Einevoll, Gaute (2020). Det har aldri vært mer aktuelt med en norsk astronaut enn n ̊a. [Fagblad]. Tekna Magasinet.
• Einevoll, Gaute (2020). Tar mikrofonen i egne hender. [Fagblad]. Forskerforum.
• Einevoll, Gaute (2020). Deltagelse i Abels Tårn. [Radio]. NRK.
• Einevoll, Gaute (2020). Deltagelse i Reiseradioen. [Radio]. NRK.
• Einevoll, Gaute (2020). Deltagelse i Abels Tårn. [Radio]. NRK.
• Einevoll, Gaute (2020). Deltagelse i Abels Tårn. [Radio]. NRK.
• Einevoll, Gaute (2020). Deltagelse i Abels Tårn. [Radio]. NRK.
• Einevoll, Gaute (2020). Kan vi regne ut hvordan vi tenker?
• Einevoll, Gaute (2020). Towards a multipurpose cortical network model.
• Einevoll, Gaute (2020). Kan hjernen gå tom for plass? [Internett]. forskning.no.
• Einevoll, Gaute (2020). Deltagelse i podcasten Romkapsel. [Internett]. Podcast.
• Einevoll, Gaute (2020). Deltager i podcasten Teknokratiet. [Internett]. Podcast: Teknokratiet.
• Einevoll, Gaute & Pettersen, Klas Henning (2020). Deltagelse i podcasten NORDE. [Internett]. Podcast.
• Einevoll, Gaute & Pettersen, Klas Henning (2020). Deltagelse i podcasten NORDE. [Internett]. Podcast.
• Mäki-Marttunen, Tuomo; Edwards, Andrew G; Einevoll, Gaute & Blackwell, Kim T (2020). Biochemically detailed single compartmental model for neocortical postsynaptic long term plasticity.
• Einevoll, Gaute (2020). Leveraging data, tools and models to gain new insights in mouse visual cortex.
• Einevoll, Gaute (2020). Why model brain signals?
• Iannella, Nicolangelo Libero; Prydz, Kristian; Malthe-Sørensen, Anders; Einevoll, Gaute & Fyhn, Marianne (2020). A framework for modelling neuronal-ECM signalling.
• Einevoll, Gaute & Spurkland, Anne (2020). Om koronaviruset – Med Anne Spurkland #14. [Internett]. Vett og Viten.
• Einevoll, Gaute & Spurkland, Anne (2020). Om coronaviruset. En oppdatering – med Anne Spurkland #21. [Internett]. Vett og Viten.
• Stasik, Alexander Johannes; Hagen, Espen; Skaar, Jan Eirik; Ness, Torbjørn V & Einevoll, Gaute (2019). Estimating parameters of biological neuronal networks using Convolutional Neural Networks.
• Røyne, Anja & Einevoll, Gaute (2019). Vett og vitenskap: Om grunnstoffer. [Internett]. Podcast.
• Hagen, Espen; Stasik, Alexander Johannes; Billeh, Yazan; Siegle, Joshua H.; Dai, Kael & Rimehaug, Atle Eskeland [Vis alle 14 forfattere av denne artikkelen] (2019). Comparing spikes and the local field potential (LFP) in V1 between experimental data and a comprehensive biophysical model.
• Stasik, Alexander Johannes; Hagen, Espen; Skaar, Jan Eirik; Ness, Torbjørn V & Einevoll, Gaute (2019). Estimating parameters of biological neuronal networks using Convolutional Neural Networks.
• Cañada, Pablo Martinez; Ness, Torbjørn V; Einevoll, Gaute; Fellin, Tommaso & Panzeri, Stefano (2019). Computing the Electroencephalogram (EEG) from Point-Neuron Networks.
• Sætra, Marte Julie; Einevoll, Gaute & Halnes, Geir (2019). A two-compartment neuron model with ion conservation and ion pumps.
• Mäki-Marttunen, Tuomo; Einevoll, Gaute; Devor, Anna; Phillips, Wiliam; Dale, Anders M. & Andreassen, Ole Andreas (2019). A computational model of the spontaneous activity of gonadotropin-releasing cells in the teleos fish medaka.
• Einevoll, Gaute & Østby, Hilde (2019). Podcast #5 om hukommelse i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Halnes, Geir; Tennøe, Simen; Einevoll, Gaute; Haug, Trude; Weltzien, Finn-Arne & Hodne, Kjetil (2019). A computational model of the spontaneous activity of gonadotrophin-releasing cells in the teleost fish models.
• Einevoll, Gaute & Sverdrup-Thygeson, Anne (2019). Podcast #6 om insekter i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Næss, Solveig; Halnes, Geir; Hagen, Espen; Hagler, Donald J.; Dale, Anders M. & Einevoll, Gaute [Vis alle 7 forfattere av denne artikkelen] (2019). Biophysical modelling of EEG signals.
• Einevoll, Gaute (2019). Deltagelse i Abels Tårn (NRK P2, NRK2). [TV]. NRK.
• Einevoll, Gaute (2019). Deltagelse i paneldebatt om hjernen og den nevrovitenskapelige revolusjon.
• Einevoll, Gaute (2019). Using AI to interpret electrical brain signals. Bernstein Feature 2019.
• Einevoll, Gaute (2019). Deltagelse i Abels Tårn, NRK P2. [Radio]. NRK.
• Einevoll, Gaute (2019). Deltagelse i podcasten Mentaltrener. [Internett]. Podcast.
• Einevoll, Gaute & Nordengen, Kaja (2019). Podcast #2 om hjernen i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Einevoll, Gaute (2019). Podcast #1: Splitter ny podcast i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Einevoll, Gaute & Øygard, Svein Harald (2019). Podcast #7 om å være Islands sentralbanksjef i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Einevoll, Gaute (2019). The too large role of statistics in neuroscience.
• Einevoll, Gaute (2019). Dommer i Forsker Grand Prix. [TV]. NRK.
• Einevoll, Gaute (2019). Hjerneforsker: Du lager din egen, personlige modell av virkeligheten. [Internett]. forskning.no.
• Einevoll, Gaute (2019). Lager kunstig tale av hjernesignaler. [Internett]. NRK Viten.
• Einevoll, Gaute (2019). Towards multipurpose biophysics-based mathematical models of cortical circuits.
• Einevoll, Gaute (2019). Kunstig syn - hjelper blinde å se igjen. [Fagblad]. Optikeren.
• Einevoll, Gaute (2019). Deltagelse i Slettan & Martin tar helg i NRK P1. [Radio]. NRK.
• Einevoll, Gaute & Svihus, Birger (2019). Podcast #3 om mat i podcasten Vett og vitenskap med Gaute Einevoll. [Internett]. Podcast.
• Hagen, Espen; Næss, Solveig; Ness, Torbjørn V & Einevoll, Gaute (2019). LFPy: Multimodal Modeling of Extracellular Neuronal Recordings in Python.
• Berthet, Pierre; Einevoll, Gaute & Ness, Torbjørn V (2019). Excitability of cortical neurons by electrical stimulation from the cortical surface.
• Einevoll, Gaute (2019). Evaluating the merit of candidate brain models with brain simulations.
• Einevoll, Gaute (2019). Physics of the mind.
• Einevoll, Gaute (2019). Towards a brain theory.

Se alle arbeider i Cristin