Ada Greve

Scientific interest

Perineuronal nets (PNNs) are a specialised extracellular matrix that surrounds parvalbumin-expressing neurons in the brain. I am interested in the biochemical characterisation of PNNs in mice. For now my main focus is establishing a reliable protocol for organotypic slice culture for whole mouse brain. These tissue cultures will be labelled with radioactive sulphate to detect changes in the proteoglycan component of the perineuronal nets at different developmental stages and in response to knockouts of PNN-regulating proteins.

Teaching

In spring 2020, I was a teaching assistant for the BIOS1130 - Biokjemi I course.

Background

I obtained BSc (Hons) in Biochemistry at the University of Edinburgh. My bachelor thesis was focused on the effects of chlorpromazine and acetaminophen on HepaRG cell culture. I continued with MSc Biochemistry at the University of Tübingen. As part of that programme, I had the opportunity to complete two internships in the field of neural development at Max Planck Institute in Tübingen and at Sars Institute in Bergen. This has led me to work on human neurodegenerative diseases at UiB and, eventually, on neural plasticity at UiO.