idamst

• Reinar, William Brynildsen; Greulich, Anne; Stø, Ida Myhrer; Knutsen, Jonfinn Mordekai Blix; Reitan, Trond & Tørresen, Ole K. [Show all 9 contributors for this article] (2023). Adaptive protein evolution through length variation of short tandem repeats in Arabidopsis. Science Advances. 9(12), p. 1–10. doi: 10.1126/sciadv.add6960. Full text in Research Archive Show summary

  Intrinsically disordered protein regions are of high importance for biotic and abiotic stress responses in plants. Tracts of identical amino acids accumulate in these regions and can vary in length over generations because of expansions and retractions of short tandem repeats at the genomic level. However, little attention has been paid to what extent length variation is shaped by natural selection. By environmental association analysis on 2514 length variable tracts in 770 whole-genome sequenced Arabidopsis thaliana, we show that length variation in glutamine and asparagine amino acid homopolymers, as well as in interaction hotspots, correlate with local bioclimatic habitat. We determined experimentally that the promoter activity of a light-stress gene depended on polyglutamine length variants in a disordered transcription factor. Our results show that length variations affect protein function and are likely adaptive. Length variants modulating protein function at a global genomic scale has implications for understanding protein evolution and eco-evolutionary biology.

• Stø, Ida Myhrer; Orr, Russell; Fooyontphanich, Kim; Jin, Xu; Knutsen, Jonfinn Mordekai Blix & Fischer, Urs [Show all 9 contributors for this article] (2015). Conservation of the abscission signaling peptide IDA during Angiosperm evolution: Withstanding genome duplications and gain and loss of the receptors HAE/HSL2. Frontiers in Plant Science. 6(OCTOBER). doi: 10.3389/fpls.2015.00931. Full text in Research Archive
• Aalen, Reidunn B.; Wildhagen, Mari; Stø, Ida Myhrer & Butenko, Melinka Alonso (2013). IDA: a peptide ligand regulating cell separation processes in Arabidopsis. Journal of Experimental Botany. ISSN 0022-0957. 64(17), p. 5253–5261. doi: 10.1093/jxb/ert338. Full text in Research Archive
• Kumpf, Robert; Shi, Chunlin; Larrieu, Antoine; Stø, Ida Myhrer; Butenko, Melinka Alonso & Péret, Benjamin [Show all 9 contributors for this article] (2013). Floral organ abscission peptide IDA and its HAE/HSL2 receptors control cell separation during lateral root emergence. Proceedings of the National Academy of Sciences of the United States of America (PNAS). ISSN 0027-8424. 110(13), p. 5235–5240. doi: 10.1073/pnas.1210835110. Full text in Research Archive

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• Herrmann, Ullrich; WILDHAGEN, Mari; Stø, Ida Myhrer; Butenko, Melinka Alonso & Aalen, Reidunn B. (2014). Secreted IDA-LIKE peptide ligands and their receptors regulate crucial aspects of root development – root cap sloughing, gravitropism and meristem length. Full text in Research Archive

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