mariwild

• Holland, Petter; Istre, Mette Stausland; Ali, Maryan Mohamed; Gedde-Dahl, Tobias; Buechner, Jochen & Wildhagen, Mari [Show all 12 contributors for this article] (2024). Epigenetic aging of human blood cells is influenced by the age of the host body. Aging Cell. ISSN 1474-9718. 23(5), p. 1–5. doi: 10.1111/acel.14112. Full text in Research Archive
• Holland, Petter; Wildhagen, Mari; Istre, Mette Stausland; Reiakvam, Olaug Marie; Dahl, John Arne & Søraas, Arne Vasli (2022). Cri du chat syndrome patients have DNA methylation changes in genes linked to symptoms of the disease. Clinical Epigenetics. 14(1). doi: 10.1186/s13148-022-01350-3. Full text in Research Archive
• Furumizu, Chihiro; Krabberød, Anders Kristian; Hammerstad, Marta; Alling, Renate; Wildhagen, Mari & Sawa, Shinichiro [Show all 7 contributors for this article] (2021). The sequenced genomes of non-flowering land plants reveal the innovative evolutionary history of peptide signaling. The Plant Cell. ISSN 1040-4651. 33(9), p. 2915–2934. doi: 10.1093/plcell/koab173. Full text in Research Archive Show summary

  Abstract An understanding of land plant evolution is a prerequisite for in-depth knowledge of plant biology. Here we extract and explore information hidden in the increasing number of sequenced plant genomes, from bryophytes to angiosperms, to elucidate a specific biological question—how peptide signaling evolved. To conquer land and cope with changing environmental conditions, plants have gone through transformations that must have required innovations in cell-to-cell communication. We discuss peptides mediating endogenous and exogenous changes by interaction with receptors activating intracellular molecular signaling. Signaling peptides were discovered in angiosperms and operate in tissues and organs such as flowers, seeds, vasculature, and 3D meristems that are not universally conserved across land plants. Nevertheless, orthologs of angiosperm peptides and receptors have been identified in nonangiosperms. These discoveries provoke questions regarding coevolution of ligands and their receptors, and whether de novo interactions in peptide signaling pathways may have contributed to generate novel traits in land plants. The answers to such questions will have profound implications for the understanding of the evolution of cell-to-cell communication and the wealth of diversified terrestrial plants. Under this perspective, we have generated, analyzed, and reviewed phylogenetic, genomic, structural, and functional data to elucidate the evolution of peptide signaling.

• Shi, Chunlin; Wangenheim, Daniel von; Herrmann, Ullrich; Wildhagen, Mari; Kulik, Ivan & Kopf, Andreas [Show all 16 contributors for this article] (2018). The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. ISSN 2055-026X. 4(8), p. 596–604. doi: 10.1038/s41477-018-0212-z. Full text in Research Archive
• Santiago, Julia; Brandt, Benjamin; Wildhagen, Mari; Hohmann, Ulrich; Hothorn, Ludwig A. & Butenko, Melinka Alonso [Show all 7 contributors for this article] (2016). Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission. eLIFE. 5(2016). doi: 10.7554/eLife.15075. Full text in Research Archive
• Czyzewicz, Nathan; Wildhagen, Mari; Cattaneo, Pietro; Stahl, Yvonne; Pinto, Karine Gustavo & Aalen, Reidunn B. [Show all 10 contributors for this article] (2015). Antagonistic peptide technology for functional dissection of CLE peptides revisited. Journal of Experimental Botany. ISSN 0022-0957. 66(17), p. 5367–5374. doi: 10.1093/jxb/erv284. Full text in Research Archive
• Estornell, Leandro H.; Wildhagen, Mari; Perez-Amador, Miguel A.; Talon, Manuel; Tadeo, Francisco R. & Butenko, Melinka Alonso (2015). The IDA peptide controls abscission in Arabidopsis and citrus. Frontiers in Plant Science. 6(NOVEMBER). doi: 10.3389/fpls.2015.01003. Full text in Research Archive
• Butenko, Melinka Alonso; Wildhagen, Mari; Albert, Markus; Jehle, Anna; Kalbacher, Hubert & Aalen, Reidunn B. [Show all 7 contributors for this article] (2014). Tools and strategies to match peptide-ligand receptor pairs. The Plant Cell. ISSN 1040-4651. 26(5), p. 1838–1847. doi: 10.1105/tpc.113.120071. Full text in Research Archive
• Aalen, Reidunn B.; Wildhagen, Mari; Stø, Ida Myhrer & Butenko, Melinka Alonso (2013). IDA: a peptide ligand regulating cell separation processes in Arabidopsis. Journal of Experimental Botany. ISSN 0022-0957. 64(17), p. 5253–5261. doi: 10.1093/jxb/ert338. Full text in Research Archive

View all works in NVA