Deregulation of stress signaling pathways has an important role in cancer cells. My focus is on stress response pathways in prostate cancer cells that are involved in homeostasis and protection from apoptosis. I use in vitro and in vivo model systems to explore the molecular mechanisms of how these pathways may affect prostate carcinogenesis.
- Jin, Yang; Ling, Wang; Qu, Su; Sheng, Xia; Kristian, Alexandr; Mælandsmo, Gunhild; Pällmann, Nora; Yuca, Erkan; Tekedereli, Ibrahim; Gorgulu, Kivanc; Alpay, Neslihan; Sood, Anil K.; Lopez-Berestein, Gabriel; Fazli, Ladan; Rennie, Paul S.; Risberg, Bjørn Åke; Wæhre, Haakon; Danielsen, Håvard Emil; Ozpolat, Bulent & Saatcioglu, Fahri (2015). STAMP2 increases oxidative stress and is critical for prostate cancer. EMBO Molecular Medicine. ISSN 1757-4676. 7(3), s 315- 331 . doi: 10.15252/emmm.201404181 Full text in Research Archive.