rozabl

Image of person
Could not get user data from external service

Academic interests

I have a broad range of academic interests including molecular biology, bioinformatics, several omics studies, structural biology, phylogenetics and so on. I have an increasing interest in my current field of study, which is transcriptional regulation and post translational modification, particularly SUMOylation. I have always been highly interested in interdisciplinary field of research and my current position is a great opportunity to entertain my long held interest. In my study I combine both molecular biological techniques (wet lab approach) as well as several bioinformatic analyses (dry lab approaches). Some of the bioinformatics approaches that I frequently use include

  • Genome wide analyses
    • Analysis of transcriptomic data (RNAseq)
    • Analysis of epigenomic data (ATACseq, ChIPseq)
  • 3D-structure prediction of proteins
  • Integration of protein structural information and evolutionary sequence conservation for identifying functionally important residues
  • Sequence evolutionary conservation and phylogeny 

Background

I have a B.Sc in Biology (Genetics and Molecular biology) from Ambo University in Ethiopia and an M.Sc in Biotechnology from Addis Ababa University in Ethiopia. I have a second masters degree in Molecular Biosciences with a project in Applied and structural bioinformatics that I obtained from department of Biosciences at the University of Oslo.

 

Publications

  • Rodriguez- Castañeda, Fernando; Lemma, Roza Berhanu; Cuervo Torre, Ignacio; Bengtsen, Mads; Moen, Lisa Marie; Ledsaak, Marit; Eskeland, Ragnhild & Gabrielsen, Odd Stokke (2018). The SUMO protease SENP1 and the chromatin remodeller CHD3 interact and jointly affect chromatin accessibility and gene expression. Journal of Biological Chemistry.  ISSN 0021-9258.  293(40), s 15439- 15454 . doi: 10.1074/jbc.RA118.002844 Show summary
  • Fuglerud, Bettina Maria; Lemma, Roza Berhanu; Wanichawan, Pimthanya; Sundaram, Arvind; Eskeland, Ragnhild & Gabrielsen, Odd Stokke (2017). A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function. Nucleic Acids Research.  ISSN 0305-1048.  45(13), s 7681- 7696 . doi: 10.1093/nar/gkx364

View all works in Cristin

Published Aug. 29, 2017 11:14 PM - Last modified Nov. 15, 2017 8:42 PM

Research groups