We are using aNK60-CPA Cloud PointAnalyzer from PhaseTechnology for characterizing changes in turbidity and cloud pointdetermination of our thermoresponsive samples. The instrument uses a scanningdiffusive light scattering technique to determine the turbidity changes of thesample. The sample volume needed is only 0.15 ml, and the temperature is veryaccurately controlled within the range (-60 oC to +60 oC)using Peltier elements. The heating/cooling rates can be set within the range0-30 oC/min. With this instrument even very small changes in theturbidity can be determined.
The instrument cannot be used on very acidic/basic samples, since thesecan destroy the reflective surface of the mirror. Bubble formation during theheating/cooling cycle can be a problem for some samples.