Tore Bonge-Hansen

Førsteamanuensis - Organisk kjemi
Bilde av Tore Bonge-Hansen
English version of this page
Telefon +47 22855386
Rom Ø 303
Brukernavn
Besøksadresse Sem Sælands vei 26 0371 Oslo
Postadresse Postboks 1033 0315 Oslo

Faglige interesser

Forskningsfokus ligger innenfor fagområdene organisk syntese og medisinal kjemi.

Jeg arbeider med å utvikle nye metoder for asymmetrisk syntese av legemidler eller analoger av disse.

Hovedfokus innen medisinal kjemi er på sykdommer relatert til sentralnervesystemet, f. eks. angst, depresjon, Parkinson's og Alzheimers sykdom.

Undervisning

Emneord: Kjemi, Organisk kjemi

Publikasjoner

  • Peeters, Sara; Berntsen, Linn Neerbye; Rongved, Pål & Bonge-Hansen, Tore (2019). Cyclopropanation–ring expansion of 3-chloroindoles with α-halodiazoacetates: novel synthesis of 4-quinolone-3-carboxylic acid and norfloxacin. Beilstein Journal of Organic Chemistry. ISSN 2195-951X. 15, s. 2156–2160. doi: 10.3762/bjoc.15.212. Fulltekst i vitenarkiv
  • Levchenko, Vladimir; Sundsli, Bård Edgar Vestheim; Øien-Ødegaard, Sigurd; Tilset, Mats; Hansen, Finn Knut & Hansen, Tore Bonge (2018). Bottom-Up Synthesis of Acrylic and Styrylic Rh11 Carboxylate Polymer Beads: Solid-Supported Analogs Rh2(OAc)4. European Journal of Organic Chemistry. ISSN 1434-193X. s. 6150–6157. doi: 10.1002/ejoc.201800953.
  • Viktorsson, Elvar Örn; Grøthe, Bendik Melling; Aesoy, Reidun; Sabir, Misbah; Snellingen, Simen & Åstrand, Ove Alexander Høgmoen [Vis alle 11 forfattere av denne artikkelen] (2017). Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Bioorganic & Medicinal Chemistry. ISSN 0968-0896. 25(7), s. 2285–2293. doi: 10.1016/j.bmc.2017.02.058.
  • Mortén, Magnus; Hennum, Martin & Bonge-Hansen, Tore (2016). On the cause of low thermal stability of ethyl halodiazoacetates. Beilstein Journal of Organic Chemistry. ISSN 2195-951X. 12, s. 1590–1597. doi: 10.3762/bjoc.12.155.
  • Mortén, Magnus; Hennum, Martin & Bonge-Hansen, Tore (2015). Synthesis of quinoline-3-carboxylates by a Rh(II)-catalyzed cyclopropanation-ring expansion reaction of indoles with halodiazoacetates. Beilstein Journal of Organic Chemistry. ISSN 2195-951X. 11, s. 1944–1949. doi: 10.3762/bjoc.11.210.
  • Yadav, Vitthal Narayan; Comotti, Angiolina; Sozzani, Piero; Bracco, Silvia; Bonge-Hansen, Tore & Hennum, Martin [Vis alle 7 forfattere av denne artikkelen] (2015). Microporous Molecular Materials from Dipeptides Containing Non-proteinogenic Residues. Angewandte Chemie International Edition. ISSN 1433-7851. 54(52), s. 15684–15688. doi: 10.1002/anie.201507321.
  • Aasheim, Jens Harald; Fliegl, Heike; Uggerud, Einar; Bonge-Hansen, Tore & Eisenstein, Odile (2014). Stereoselectivity through a network of non-classical CH weak interactions: A prospective study of a bicyclic organocatalytic scaffold. New Journal of Chemistry. ISSN 1144-0546. 38(12), s. 5975–5982. doi: 10.1039/c4nj01460j.
  • Bolsønes, Marianne; Bonge, Hanne Therese & Bonge-Hansen, Tore (2014). Intramolecular cyclopropanation of bromodiazoacetates. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. ISSN 0936-5214. 25(2), s. 221–224. doi: 10.1055/s-0033-1340170.
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Bonge-Hansen, Tore (2013). N,N'-Bis(2-diazoacetyl)piperazine. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 69(8). doi: 10.1107/S1600536813018801.
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Bonge-Hansen, Tore (2013). A solid-state oxidation of 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfinate to 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfonate. Acta Crystallographica Section C: Crystal Structure Communications. ISSN 0108-2701. 69, s. 778–+. doi: 10.1107/S0108270113015011.
  • Rulli, Giuseppe; Fredriksen, Kim Alex; Duangdee, Nongnaphat; Bonge-Hansen, Tore; Berkessel, Albrecht & Gröger, Harald (2013). Asymmetric Organocatalytic Aldol Reaction in Water: Mechanistic Insights and Development of a Semi-Continuously Operating Process. Synthesis (Stuttgart). ISSN 0039-7881. 45(18), s. 2512–2519. doi: 10.1055/s-0033-1338509.
  • Schnaars, Christian; Hennum, Martin & Bonge-Hansen, Tore (2013). Nucleophilic Halogenations of Diazo Compounds, a Complementary Principle for the Synthesis of Halodiazo Compounds: Experimental and Theoretical Studies. Journal of Organic Chemistry. ISSN 0022-3263. 78(15), s. 7488–7497. doi: 10.1021/jo401050c.
  • Kaupang, Åsmund & Bonge-Hansen, Tore (2013). α-Bromodiazoacetamides – a new class of diazo compounds for catalyst-free, ambient temperature intramolecular C–H insertion reactions. Beilstein Journal of Organic Chemistry. ISSN 2195-951X. 9, s. 1407–1413. doi: 10.3762/bjoc.9.157.
  • Hughes, Rachael Anne; Tølløfsrud, Magnus; Bryant, Nathan; Kaboli, Massoud; Hennum, Martin & Bonge-Hansen, Tore (2013). Diastereoselective synthesis of cyclopropyl melatonin analogues. Tetrahedron Letters. ISSN 0040-4039. 54(4), s. 318–320. doi: 10.1016/j.tetlet.2012.11.037.
  • Thvedt, Thor Håkon Krane; Kristensen, Tor Erik Holt; Sundby, Eirik; Hansen, Tore & Hoff, Bård Helge (2011). Enantioselectivity, swelling and stability of 4-hydroxyprolinol containing acrylic polymer beads in the asymmetric reduction of ketones. Tetrahedron: asymmetry. ISSN 0957-4166. 22(24), s. 2172–2178. doi: 10.1016/j.tetasy.2011.12.001. Fulltekst i vitenarkiv
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2011). 2-Diazo-1-(1,1-dioxothiomorpholin-4-yl)ethanone. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 67, s. O1844–U2037. doi: 10.1107/S1600536811023774.
  • Yadav, Vitthal Narayan; Hansen, Tore & Gorbitz, Carl Henrik (2011). 1,1 '-(4,4 '-Bipiperidine-1,1 '-diyl)bis(2,2,2-trifluoroethanone). Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 67, s. O1691–U733. doi: 10.1107/S1600536811022434.
  • Bonge, Hanne Therese & Hansen, Tore (2011). Halodiazoacetates as useful tools for selective halo-functionalization. Pure and Applied Chemistry. ISSN 0033-4545. 83(3), s. 565–575. doi: 10.1351/PAC-CON-10-10-18.
  • Bonge, Hanne Therese; Kaboli, Massoud & Hansen, Tore (2010). Rh(II) catalysts with 4-hydroxyproline-derived ligands. Tetrahedron Letters. ISSN 0040-4039. 51(41), s. 5375–5377. doi: 10.1016/j.tetlet.2010.07.115.
  • Bonge, Hanne Therese & Hansen, Tore (2010). Insights on Rh(II) carbenoid reactivity. Tetrahedron Letters. ISSN 0040-4039. 51(41), s. 5378–5381. doi: 10.1016/j.tetlet.2010.07.116.
  • Bonge, Hanne Therese & Hansen, Tore (2010). Computational comparison of Rh-2(esp)(2) and Rh-2(O2CH)(4) as catalysts in a carbenoid reaction. Tetrahedron Letters. ISSN 0040-4039. 51(40), s. 5298–5301. doi: 10.1016/j.tetlet.2010.07.169.
  • Kristensen, Tor Erik Holt & Hansen, Tore (2010). Polymer-Supported Chiral Organocatalysts: Synthetic Strategies for the Road Towards Affordable Polymeric Immobilization. European Journal of Organic Chemistry. ISSN 1434-193X. s. 3179–3204. doi: 10.1002/ejoc.201000319.
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2010). tert-Butyl 4-(2-diazoacetyl)piperazine-1-carboxylate. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 66, s. O2199–U467. doi: 10.1107/S1600536810016211.
  • Bonge, Hanne Therese & Hansen, Tore (2010). Computational Study of Cyclopropanation Reactions with Halodiazoacetates. Journal of Organic Chemistry. ISSN 0022-3263. 75(7), s. 2309–2320. doi: 10.1021/jo100113b.
  • Kristensen, Tor Erik Holt; Vestli, Kristian; Jakobsen, Martin Gjerde; Hansen, Finn Knut & Hansen, Tore (2010). General Approach for Preparation of Polymer-Supported Chiral Organocatalysts via Acrylic Copolymerization. Journal of Organic Chemistry. ISSN 0022-3263. 75(5), s. 1620–1629. doi: 10.1021/jo902585j.
  • Bonge, Hanne Therese & Hansen, Tore (2010). Computational Study of C-H Insertion Reactions with Ethyl Bromodiazoacetate. European Journal of Organic Chemistry. ISSN 1434-193X. s. 4355–4359. doi: 10.1002/ejoc.201000531.
  • Gorbitz, Carl Henrik; Hansen, Tore & Vestli, Kristian (2009). (1S,5R)-1-(3,4-Dichlorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 65. doi: 10.1107/S1600536809007533.
  • Gorbitz, Carl Henrik; Hansen, Tore & Vestli, Kristian (2009). (1S,5R)-1-(4-Fluorophenyl)-3-azoniabicyclo[3.1.0]hexane chloride. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 65. doi: 10.1107/S1600536809006953.
  • Kristensen, Tor Erik Holt; Hansen, Finn Knut & Hansen, Tore (2009). The Selective O-Acylation of Hydroxyproline as a Convenient Method for the Large-Scale Preparation of Novel Proline Polymers and Amphiphiles. European Journal of Organic Chemistry. ISSN 1434-193X. s. 387–395. doi: 10.1002/ejoc.200800941.
  • Bonge, Hanne Therese & Hansen, Tore (2009). Intermolecular C-H and Si-H Insertion Reactions with Halodiazoacetates. Synthesis (Stuttgart). ISSN 0039-7881. s. 91–96. doi: 10.1055/s-0028-1083272.
  • Kristensen, Tor Erik Holt; Vestli, Kristian; Fredriksen, Kim A; Hansen, Finn Knut & Hansen, Tore (2009). Synthesis of Acrylic Polymer Beads for Solid-Supported Proline-Derived Organocatalysts. Organic Letters. ISSN 1523-7060. 11(14), s. 2968–2971. doi: 10.1021/ol901134v.
  • Rosenberg, Marianne Lenes; Aasheim, Jens Harald; Trebbin, M; Uggerud, Einar & Hansen, Tore (2009). Synthesis of a 1,3,4,5-tetrahydrobenzindole beta-ketoester. Tetrahedron Letters. ISSN 0040-4039. 50(47), s. 6506–6508. doi: 10.1016/j.tetlet.2009.09.032.
  • Kristensen, Tor Erik Holt; Vestli, Kristian; Hansen, Finn Knut & Hansen, Tore (2009). New Phenylglycine-Derived Primary Amine Organocatalysts for the Preparation of Optically Active Warfarin. European Journal of Organic Chemistry. ISSN 1434-193X. s. 5185–5191. doi: 10.1002/ejoc.200900664.
  • Bonge, Hanne Therese & Hansen, Tore (2008). Rhodium(II) catalysed three-component coupling: a novel reaction of in situ generated iodonium ylides. Tetrahedron Letters. ISSN 0040-4039. 49, s. 57–61. doi: 10.1016/j.tetlet.2007.11.021.
  • Kaupang, Åsmund; Bolsones, M; Gamadeku, T; Hansen, Tore; Hennum, MJ & Gorbitz, Carl Henrik (2008). 2SR,3RS)-Benzyl[4-chloro-1-(4-chlorophenyl)-1-methoxycarbonyl-2-butyl]ammonium chloride. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 64, s. O2038–U4798. doi: 10.1107/S1600536808030742.
  • Bonge, Hanne Therese; Pintea, Beniamin Nicolae & Hansen, Tore (2008). Highly efficient formation of halodiazoacetates and their use in stereoselective synthesis of halocyclopropanes. Organic and biomolecular chemistry. ISSN 1477-0520. 6(20), s. 3670–3672. doi: 10.1039/b814374a.
  • Bonge, Hanne Therese & Hansen, Tore (2007). Cyclopropanation of olefins with nitromethane. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. ISSN 0936-5214. doi: 10.1055/s-2006-958437.
  • Melby, Trude; Hughes, Rachael Anne & Hansen, Tore (2007). Diastereoselective synthesis of 1-aryl-2-amino-cyclopropane carboxylates. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. ISSN 0936-5214. s. 2277–2279. doi: 10.1055/s-2007-985587.
  • Bruvoll, M; Hansen, Tore & Uggerud, Einar (2007). Organocatalysis: quantum of nuclephilic addition to alpha,beta-unsaturated carbonyl compounds. Journal of Physical Organic Chemistry. ISSN 0894-3230. 20, s. 206–213. doi: 10.1002/poc.1170.
  • Roggen, Heidi; Kehler, J; Stensbol, TB & Hansen, Tore (2007). Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 17. doi: 10.1016/j.bmcl.2007.02.054.

Se alle arbeider i Cristin

  • Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars & Rongved, Pål (2016). Total synthesis and initial antileukemic evaluation of the phenazine 5,10-dioxide natural products iodinin and myxin.
  • Grøthe, Bendik Melling; Snellingen, Simen; Viktorsson, Elvar Örn; Prandina, Anthony; Åstrand, Ove Alexander Høgmoen & Bonge-Hansen, Tore [Vis alle 7 forfattere av denne artikkelen] (2015). The first efficient synthesis and preliminary biological effect of the 1,6-dihydroxyphenazine-N5,N10-dioxide (Iodinin) and 1-hydroxy-6-methoxyphenazine-N5,N10-dioxide (Myxin).
  • Levchenko, Vladimir; Øien-Ødegaard, Sigurd; Tilset, Mats & Bonge-Hansen, Tore (2015). Novel strategy for Synthesis of Rhodium(II)-containing Polymer Catalysts.
  • Kristensen, Tor Erik & Bonge-Hansen, Tore (2013). Polymer and Mesoporous Material Supported Organocatalysts. I Dalko, Peter I. (Red.), Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications, Volume 2. Wiley-VCH. ISSN 978-3-527-33236-6. s. 651–672. doi: 10.1002/9783527658862.ch23.
  • Hennum, Martin; Odden, Hege Hortemo; Gundersen, Lise-Lotte & Hansen, Tore (2012). Methodology towards the total synthesis of asmarines.
  • Kristensen, Tor Erik & Bonge-Hansen, Tore (2011). Synthesis of Chiral Catalysts Supported on Organic Polymers. I Gruttadauria, Michelangelo & Giacalone, Francesco (Red.), Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications. John Wiley & Sons. ISSN 978-0-470-64136-1. s. 209–256. doi: 10.1002/9781118087992.ch4.
  • Kristensen, Tor Erik & Hansen, Tore (2008). Immobilization of proline by polymerization of acrylic derivatives.
  • Bonge, Hanne Therese & Hansen, Tore (2008). Novel carbenoid reactions.
  • Rosenberg, Marianne Lenes & Hansen, Tore (2007). Synthesis of an analogue of Uhle's ketone.
  • Bonge, Hanne Therese & Hansen, Tore (2007). Nitromethane as a iodonium ylide precursor.
  • Hansen, Finn Knut; Hansen, Tore & Kristensen, Tor Erik (2007). Solid phase organocatalysis.
  • Aasheim, Jens & Hansen, Tore (2007). Investigating organocatalytic reactions by supercomputing.
  • Boman, Kjartan & Hansen, Tore (2007). New catalysts for asymmetric organocatalysis.
  • Berntsen, Linn Neerbye; Hansen, Tore Bonge & Rongved, Pål (2018). Rh(II)-catalyzed cyclopropanation-ring expansion of 7-azaindoles with halodiazoacetates and indoles with halodiazophosphonates. Kjemisk Institutt, Universitetet i Oslo.
  • Araba, Taofik Olasile; Bonge-Hansen, Tore & Hansen, Finn Knut (2016). Progress towards the synthesis and self-assembly of amphiphilic drug conjugates of Iodinin. Universitetet i Oslo.
  • Levchenko, Vladimir; Bonge-Hansen, Tore & Tilset, Mats (2016). Design and Synthesis of Novel Rh(II)-containing Polymer Catalysts. Organometallic Gold(III) Catalysis in Organic Synthesis. Universitetet i Oslo.
  • Grøthe, Bendik Melling; Bonge-Hansen, Tore & Rongved, Pål (2015). Syntese av myxin og myxinderivater som potensielle legemidler mot akutt myelogen leukemi. Universitetet i Oslo.
  • Yadav, Vitthal Narayan; Görbitz, Carl Henrik & Bonge-Hansen, Tore (2013). Design and Synthesis of Microporous Dipeptide Structures and Guanidinium-carboxylate-based Organic Supramolecular Materials. Universitetet i Oslo.
  • Bryukhovskiy, Alexey & Bonge-Hansen, Tore (2011). Design and synthesis of potential inhibitors of the transcription factor c-Myb. Kjemisk institutt, Universitetet i Oslo.

Se alle arbeider i Cristin

Publisert 12. juli 2010 14:42 - Sist endret 24. sep. 2012 11:24

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