Nina Frederike J Edin

Førsteamanuensis - Biofysikk og medisinsk fysikk
Bilde av Nina Frederike J Edin
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Telefon +47-22855492
Mobiltelefon +47 92812070
Rom KV330
Brukernavn
Besøksadresse Kjemibygget
Postadresse Postboks 1048 Blindern 0316 OSLO

Faglige interesser

Det vitenskapelige hovedinteresse-området er cellulære effekter av stråling og hypoksi

Jeg er spesielt opptatt av følgende:

  • Mekanismer indusert av stråling med lave doserater, som kan beskytte mod senere bestråling og mod noen typer kjemoterapi
  • TGFbeta3 og stråling
  • Nye måter å gi protonbestråling og utnytte protoner fysiske egenskaper i kreftbehandling
  • Immunogene effekter av protonstråling
  • Stråling og hypoksi 
  • DNA-uavhengige strålinginduserte mekanismer
  • Beskytter små stråledoser ved lave doserater mot kreft?

 

Emneord: Biomedisinsk fysikk, Biofysikk, Medisinsk fysikk, Strålingsfysikk, Strålingsbiofysikk, Kreft, Strålevern, Hypoxi, Lavdosestråling, Cellekinetikk, Celle- og molekylærbiologi, Livsvitenskap - life science

Publikasjoner

  • Grigalavicius, Mantas; Mastrangelopoulou, Maria; Berg, Kristian; Arous, D; Ménard, Mathilde; Raabe-Henriksen, T; Brondz, Efim; Siem, Sunniva; Görgen, Andreas; Edin, Nina Frederike J; Malinen, Eirik & Theodossiou, Theodossis (2019). Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production. Nature Communications.  ISSN 2041-1723.  10(1) . doi: 10.1038/s41467-019-12042-7
  • Printzell, Lisa; Reseland, Janne Elin; Edin, Nina Frederike J & Ellingsen, Jan Eirik (2019). Effects of ionizing irradiation and interface backscatter on human mesenchymal stem cells cultured on titanium surfaces. European Journal of Oral Sciences.  ISSN 0909-8836. . doi: 10.1111/eos.12654
  • Bousquet, Paula; Sandvik, Joe Alexander; Edin, Nina Frederike J & Krengel, Ute (2018). Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  495(1), s 1562- 1566 . doi: 10.1016/j.bbrc.2017.11.183 Fulltekst i vitenarkiv.
  • Mikalsen, Stine Gyland; Edin, Nina Frederike J; Sandvik, Joe Alexander & Pettersen, Erik O (2018). Separation of two sub-groups with different DNA content after treatment of T-47D breast cancer cells with low dose-rate irradiation and intermittent hypoxia. Acta Radiologica.  ISSN 0284-1851.  59(1), s 26- 33 . doi: 10.1177/0284185117699999
  • Mikalsen, Stine Gyland; Mikalsen, Lars Tore G; Sandvik, Joe Alexander; Aarnes, Eva-Katrine; Fenne, Siri; Flatmark, Kjersti; Lyng, Heidi; Edin, Nina Frederike J & Pettersen, Erik O (2018). Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model. Acta Oncologica.  ISSN 0284-186X.  57(9), s 1216- 1224 . doi: 10.1080/0284186X.2018.1457223
  • Dahle, Tordis Johnsen; Rykkelid, Anne Marit; Stokkevåg, Camilla Hanquist; Mairani, Andrea; Görgen, Andreas; Edin, Nina Frederike J; Rørvik, Eivind; Fjæra, Lars Fredrik; Malinen, Eirik & Ytre-Hauge, Kristian (2017). Monte Carlo simulations of a low energy proton beamline for radiobiological experiments. Acta Oncologica.  ISSN 0284-186X.  56(6), s 779- 786 . doi: 10.1080/0284186X.2017.1289239
  • Edin, Nina Frederike J; Altaner, Čestmír; Altanerova, Veronica; Ebbesen, Peter & Pettersen, Erik O (2016). Low-Dose-Rate Irradiation for 1 Hour Induces Protection Against Lethal Radiation Doses but Does Not Affect Life Span of DBA/2 Mice. Dose-Response.  ISSN 1559-3258.  14(4) . doi: 10.1177/1559325816673901
  • Edin, Nina Frederike J; Altaner, Čestmír; Altanerova, Veronica & Ebbesen, Peter (2015). TGF-Bdependent modification of radiosensitivity in reporter cells exposed to serum from whole-body low dose-rate irradiated mice. Dose-Response.  ISSN 1559-3258.  13(1) . doi: 10.2203/dose-response.14-015.Edin
  • Edin, Nina Frederike J; Christoffersen, Stine; Fenne, Siri; Sandvik, Joe Alexander & Pettersen, Erik O (2015). Cell inactivation by combined low dose-rate irradiation and intermittent hypoxia. International Journal of Radiation Biology.  ISSN 0955-3002.  91(4), s 336- 345 . doi: 10.3109/09553002.2014.996262
  • Edin, Nina Frederike J (2014). The role of interleukin-13 in the removal of hyper-radiosensitivity by priming irradiation. Journal of radiation research.  ISSN 0449-3060.  55(6), s 1066- 1074 . doi: 10.1093/jrr/rru053 Fulltekst i vitenarkiv.
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Chang, Cheng; Bergersen, Linda Hildegard & Pettersen, Erik O (2014). The roles of TGF-β3 and peroxynitrite in removal of hyper-radiosensitivity by priming irradiation. International Journal of Radiation Biology.  ISSN 0955-3002.  90(7), s 527- 537 . doi: 10.3109/09553002.2014.906767
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Vollan, Hilde Synnøve; Reger, Katharina; Görlach, Agnes & Pettersen, Erik O (2013). The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation. Journal of radiation research.  ISSN 0449-3060.  54(6), s 1015- 1028 . doi: 10.1093/jrr/rrt061
  • Chang, Cheng; Edin, Nina Frederike J; Lauritzen, Knut Husø; Aspmodal, Ida; Christoffersen, Stine; Jian, Liu; Rasmussen, Lene Juel; Pettersen, Erik O; Gao, Xiaoqun & Bergersen, Linda Hildegard (2012). Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells. Cellular Oncology.  ISSN 1570-5870.  35(3), s 217- 227 . doi: 10.1007/s13402-012-0081-9
  • Edin, Nina Frederike J; Olsen, Dag Rune; Sandvik, Joe Alexander; Malinen, Eirik & Pettersen, Erik O (2012). Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenation. International Journal of Radiation Biology.  ISSN 0955-3002.  88(4), s 311- 319 . doi: 10.3109/09553002.2012.646046
  • Edin, Nina Frederike J; Olsen, Dag Rune; Stokke, Trond; Sandvik, Joe Alexander; Ebbesen, Peter & Pettersen, Erik O (2009). Mechanisms of the elimination of low dose hyper-radiosensitivity in T-47D cells by low dose-rate priming. International Journal of Radiation Biology.  ISSN 0955-3002.  85(12), s 1157- 1165 . doi: 10.3109/09553000903242107
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Olsen, Dag Rune & Pettersen, Erik O (2009). The elimination of low dose hyper-radiosensitivity by transfer of irradiated-cell conditioned medium depends on dose rate. Radiation Research.  ISSN 0033-7587.  171(1), s 22- 32
  • Edin, Nina Frederike J; Olsen, Dag Rune; Stokke, T & Pettersen, Erik O (2007). Recovery of low-dose hyper-radiosensitivity following a small priming dose depends on priming dose-rate. International Journal of Low Radiation.  ISSN 1477-6545.  4(1), s 69- 86 . doi: 10.1504/IJLR.2007.014491
  • Pettersen, Erik O; Bjørhovde, Ingunn; Søvik, Åste; Edin, Nina Frederike J; Zachar, V; Hole, Eli Olaug; Sandvik, Joe Alexander & Ebbesen, P (2007). Response of chronic hypoxic cells to low dose-rate irradiation. International Journal of Radiation Biology.  ISSN 0955-3002.  83 . doi: 10.1080/09553000701287791

Se alle arbeider i Cristin

  • Edin, Nina Frederike J (2019). The role of TGF-beta3 in radioresistance.
  • Edin, Nina Frederike J; Rykkelid, Anne Marit; Görgen, Andreas; Baker, Agnes; Siem, Sunniva; Ytre-Hauge, Kristian & Malinen, Eirik (2019). Very high yield of double strand breaks found at the distal end of the proton Bragg peak. Radiotherapy and Oncology.  ISSN 0167-8140.  133, s 594- 594
  • Rykkelid, Anne Marit; Tormodsrud, Vera; Siem, Sunniva; Görgen, Andreas; Ytre-Hauge, Kristian; Malinen, Eirik & Edin, Nina Frederike J (2019). Very high RBE values found at the distal end of the proton Bragg peak.
  • Rykkelid, Anne Marit; Siem, Sunniva; Ytre-Hauge, Kristian; Malinen, Eirik & Edin, Nina Frederike J (2018). Very high relative biological effectiveness found at the distal end of the proton Bragg peak. Radiotherapy and Oncology.  ISSN 0167-8140.  127, s 1259- 1259
  • Dahle, Tordis Johnsen; Rykkelid, Anne Marit; Stokkevåg, Camilla Hanquist; Görgen, Andreas; Edin, Nina Frederike J; Malinen, Eirik & Ytre-Hauge, Kristian (2017). Monte Carlo simulations of a low-energy proton beam and estimation of LET distributions. Radiotherapy and Oncology.  ISSN 0167-8140.  123, s 179- 180
  • Hole, Eli Olaug; Edin, Nina Frederike J; Malinen, Eirik; Pettersen, Erik O & Sagstuen, Einar (2017). Biophysics and medical physics at UiO: Research and education. An incomplete overview..
  • Rykkelid, Anne Marit; Siem, Sunniva; Görgen, Andreas; Ytre-Hauge, Kristian; Brondz, Efim; Sandvik, Joe Alexander; Pettersen, Erik O; Malinen, Eirik & Edin, Nina Frederike J (2017). A high-resolution proton irradiator for in vitro studies of relative biological effectiveness.
  • Frettem, Åshild Kvammen; Edin, Nina Frederike J; Galtung, Hilde & Søland, Tine Merete (2016). Tumour associated Aquaporin-3 and hypoxia in an oral squamous cell carcinoma cell line.
  • Edin, Nina Frederike J (2014). Induction of protection against radiation damage.
  • Edin, Nina Frederike J; altaner, cestmir; Altanerova, Veronica & Ebbesen, Peter (2014). TGF-3 IN PROTECTION AGAINST RADIATION DAMAGE.
  • Christoffersen, Stine; Sandvik, Joe Alexander; Pettersen, Erik O & Edin, Nina Frederike J (2012). Cell respiration, hypoxia and low dose rate radiation.
  • Edin, Nina Frederike J (2012). Cycling hypoxia and inverse radiomodifying effects of oxygen at ultra-low radiation doses.
  • Edin, Nina Frederike J (2012). Hvor farlig er radioaktiv stråling?.
  • Edin, Nina Frederike J & Ebbesen, Peter (2012). Effect of small doses whole-body γ-radiation given at low dose-rate to mice with normal micro-flora.
  • Edin, Nina Frederike J; Pettersen, Erik O; Sandvik, Joe Alexander; Bergersen, Linda Hildegard; Chang, Cheng; Vollan, Hilde Synnøve; Görlach, Agnes; Reger, Katharina & Ebbesen, Peter (2012). The role of TGFb3 and induced nitric oxide synthase activity in connection with induced resistance against low dose hyper-radiosensitivity.
  • Edin, Nina Frederike J (2011). Low dose-rate gamma irradiation can protect against subsequent high dose-rate irradiation .
  • Edin, Nina Frederike J (2011). Molecular mechanisms for induction of sustained elimination of low dose hyper-radiosensitivity.
  • Edin, Nina Frederike J (2011). The mechanism by which reoxygenation and low dose-rate radiation turn off hyper-radiosensitivity.
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Chang, Cheng; Vollan, Hilde Synnøve; Reger, Katharina; Görlach, Agnes; Bergersen, Linda Hildegard & Pettersen, Erik O (2011). Molecular mechanisms for induction of sustained elimination of low dose hyper-radiosensitivity.
  • Edin, Nina Frederike J (2008). Elimination of low dose hyper-radiosensitivity in T-47D cells. Then significance of dose-rate and oxygen level.
  • Edin, Nina Frederike J; Olsen, Dag Rune; Sandvik, Joe Alexander; Stokke, Trond & Pettersen, Erik O (2008). Mechanisms of the elimination of low dose hyper-radiosensitivity in T-47D cells by low dose-rate priming.
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Olsen, Dag Rune & Pettersen, Erik O (2007). LOW DOSE HYPER-RADIOSENSITIVITY IN T-47D CELLS.
  • Edin, Nina Frederike J; Olsen, Dag Rune & Pettersen, Erik O (2006). Lav-dosis hypersensitivitet hos T-47D brystkræftceller.
  • Edin, Nina Frederike J; Sandvik, Joe Alexander; Olsen, Dag Rune & Pettersen, Erik O (2006). Intracellular signalling through medium transfer and low dose hyper-radiosensitivity.
  • Edin, Nina Frederike J; Olsen, Dag Rune & Pettersen, Erik O (2005). Recovery of low-dose HRS following a small priming dose depends on priming dose rate.

Se alle arbeider i Cristin

Publisert 4. nov. 2010 12:13 - Sist endret 14. aug. 2018 13:18

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