We congratulate Kathrin H. Hopmann with her recent publication in Angewandte Chemie

Kathrin H. Hopmann, one of the Principal Investigators of the Hylleraas Centre, has together with her co-workers Annette Bayer and Janakiram Vaitla published a combined experimental and computational study in Angewandte Chemie entitled Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study

The study presents a method for the generation of vinyl carbenoids from sulfoxonium ylides and FeBr2. The novel method was applied in the synthesis of diverse heterocycles such as indolizines, pyrroles, 3‐pyrrolin‐2‐ones, and furans. A reaction pathway involving iron carbenoids was proposed based on a series of control experiments and DFT calculations. The computational work revealed that an experimentally observed intermediate in fact is an off-cycle species.

Link to the article:

Published Oct. 23, 2018 2:40 PM - Last modified Oct. 23, 2018 2:40 PM