We congratulate Kathrin H. Hopmann with her recent publication in Angewandte Chemie
Kathrin H. Hopmann, one of the Principal Investigators of the Hylleraas Centre, has together with her co-workers Annette Bayer and Janakiram Vaitla published a combined experimental and computational study in Angewandte Chemie entitled Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study
The study presents a method for the generation of vinyl carbenoids from sulfoxonium ylides and FeBr2. The novel method was applied in the synthesis of diverse heterocycles such as indolizines, pyrroles, 3‐pyrrolin‐2‐ones, and furans. A reaction pathway involving iron carbenoids was proposed based on a series of control experiments and DFT calculations. The computational work revealed that an experimentally observed intermediate in fact is an off-cycle species.
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