The study presents a method for the generation of vinyl carbenoids from sulfoxonium ylides and FeBr2. The novel method was applied in the synthesis of diverse heterocycles such as indolizines, pyrroles, 3‐pyrrolin‐2‐ones, and furans. A reaction pathway involving iron carbenoids was proposed based on a series of control experiments and DFT calculations. The computational work revealed that an experimentally observed intermediate in fact is an off-cycle species.
We congratulate Kathrin H. Hopmann with her recent publication in Angewandte Chemie
Kathrin H. Hopmann, one of the Principal Investigators of the Hylleraas Centre, has together with her co-workers Annette Bayer and Janakiram Vaitla published a combined experimental and computational study in Angewandte Chemie entitled Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study
Published Oct. 23, 2018 2:40 PM
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