Ryan Scott Wilkins defended his PhD thesis

Doctoral candidate Ryan Scott Wilkins at the Department of Chemistry, UiT The Arctic University of Norway, defended his thesis "Mechanisms of enzyme adaptation to extreme environments: The rational design of a thermophilic chorismate mutase" for the degree of Philosophiae Doctor.

Photo of Ryan Scott Wilkins

Ryan Scott Wilkins

Trial lecture 

February 26th, 10:15 AM, Store Auditorium B302, Realfagsbygget

Trial lecture title:

“Protein engineering and design: from early beginnings to now”

The trial lecture was live streamed for everyone else.

Summary 

Extremophiles, especially those living in high-temperature environments, exhibit unique enzymatic mechanisms that allow survival under conditions detrimental to most life forms. Of particular interest is thermophiles, which are able to thrive at temperatures at which psychrophiles and mesophiles unfold and cease to function. The mechanisms by which these enzymes are able to overcome this temperature extreme are not yet well understood, leading to an increasing interest in studying how they function. Thermophiles have a multitude of applications under extreme conditions in industrial processes such as pharmaceuticals, waste management, and textiles, so a more complete understanding of these molecular mechanisms can lead to the development of novel enzymes for these purposes.

    Evaluation committee, Supervisors and Leader of defense

    Evaluation committee

    • Professor Fahmi Himo, Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University (1. Opponent)
    • Professor Ute Krengel, Department of Chemistry, University of Oslo (2. Opponent)
    • Professor Luca Frediani, Department of Chemistry, UiT (intern member and leader of the committee)
    • Researcher Bin Gao, Department of Chemistry, UiT (set member during the public defense)

    Supervisors 

    • Professor Bjørn Olav Brandsdal, Department of Chemistry, UiT (main supervisor)
    • Project Manager Geir Villy Isaksen, Helse Nord IKT
    • Post.doc. Bjarte Aarmo Lund, Department of Chemistry, UiT

    Leader of defense

    • Professor John Sigurd Mjøen Svendsen, Department of Chemistry, UiT
Tags: Hylleraas Centre for Quantum Molecular Sciences, Hylleraas
Published Mar. 1, 2024 8:22 PM - Last modified May 27, 2024 1:23 PM