Our researchers in the media

By CHRISTINA LARSON, Associated Press Published: August 16, 2018, 6:00 AM

Federico Fenaroli †, Urska Repnik †, Yitian Xu ‡, Kerstin Johann §, Simon Van Herck ∥, Pradip Dey ⊥, Frode Miltzov Skjeldal †, Dominik M. Frei †, Shahla Bagherifam #, Agnese Kocere †, Rainer Haag ⊥, Bruno G. De Geest ∥, Matthias Barz §, David G. Russell ‡, and Gareth Griffiths * † † Department of Biosciences, University of Oslo, Blindernveien 31, 0371 Oslo, Norway ‡ Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, C5 109 VMC, Ithaca, New York 14853, United States § Institute for Organic Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 10-14, 55099 Mainz, Germany ∥ Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium ⊥ Institute of Chemistry and Biochemistry−Organic Chemistry, Free University of Berlin, Takustrasse 3, 14195 Berlin, Germany # Department of Radiation Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, N-0310 Oslo, Norway ACS Nano, Article ASAP DOI: 10.1021/acsnano.8b04433 Publication Date (Web): August 6, 2018 Copyright © 2018 American Chemical Society *E-mail: g.w.griffiths@ibv.uio.no. Cite this: ACS Nano XXXX, XXX, XXX-XXX

Muslinger som lever på eller i bunnen er omgitt av milliarder av partikler med organisk materiale på – mat de trenger for å leve. Likevel blir de påvirket av ørsmå biter av plast mellom de andre partiklene.

KOMPAS.com - Viking adalah salah satu suku yang terkenal dengan keberanian dan profesinya sebagai perompak. Namun siapa sangka, suku penjelajah samudra itu ternyata harus mengaku kalah pada walrus, mamalia laut yang hidup di belahan Bumi utara.

Fra to enkeltceller til fullt ferdig menneske. Katharina Vestre, Linnea Vestre (ill.): DET FØRSTE MYSTERIET. Historien om deg - før du ble fodt

Loven i utakt med teknologien: Genredigering kan gjøre drømmer til virkelighet. Men de teknologiske fremskrittene setter dagens lovverk på prøve.

Forskere danner egne bedrifter: I det nye laboratoriet Sharelab på Blindern møtes forskere, bedriftsutviklere og investorer.

Forskere ved UiO har designet en DNA-vaksine som programmerer kroppens egne celler til å mobilisere immunforsvaret.

KOMPAS.com - Viking adalah salah satu suku yang terkenal dengan keberanian dan profesinya sebagai perompak. Namun siapa sangka, suku penjelajah samudra itu ternyata harus mengaku kalah pada walrus, mamalia laut yang hidup di belahan Bumi utara.

The allometric relationship between brain and body size among vertebrates is often considered a manifestation of evolutionary constraints. However, birds and mammals have undergone remarkable encephalization, in which brain size has increased without corresponding changes in body size. Here, we explore the hypothesis that a reduction of phenotypic integration between brain and body size has facilitated encephalization in birds and mammals. Using a large dataset comprising 20,213 specimens across 4,587 species of jawed vertebrates, we show that the among-species (evolutionary) brain–body allometries are remarkably constant, both across vertebrate classes and across taxonomic levels. Birds and mammals, however, are exceptional in that their within-species (static) allometries are shallower and more variable than in other vertebrates. These patterns are consistent with the idea that birds and mammals have reduced allometric constraints that are otherwise ubiquitous across jawed vertebrates. Further exploration of ontogenetic allometries in selected taxa of birds, fishes and mammals reveals that birds and mammals have extended the period of fetal brain growth compared to fishes. Based on these findings, we propose that avian and mammalian encephalization has been contingent on increased variability in brain growth patterns.

The collapse in the walrus tusk trade triggered an economic crisis for early Viking colonists in Greenland that led to the downfall of its settlements and churches, according to new research.

I marinai norreni furono probabilmente i primi europei a sbarcare in quello che qualche secolo dopo sarebbe diventato il Continente americano [13 agosto 2018]

WASHINGTON (AP) — Clues to the mystery of why Viking colonies in Greenland flourished and fell have been found in the DNA of medieval walrus bones housed in more than a dozen European museums.

Mostakim SK †, Soutick Nandi †, Rakesh Kumar Singh ‡, Vishal Trivedi ‡, and Shyam Biswas * † † Department of Chemistry and ‡ Malaria Research Group, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India Inorg. Chem., Article ASAP DOI: 10.1021/acs.inorgchem.8b01310 Publication Date (Web): August 9, 2018 Copyright © 2018 American Chemical Society *Phone: 91-3612583309. Fax: 91-3612582349. E-mail: sbiswas@iitg.ernet.in. Cite this: Inorg. Chem. XXXX, XXX, XXX-XXX Synopsis Boronic acid functionalized Hf-based UiO-66 metal−organic framework was synthesized under solvothermal conditions. It could detect the peroxynitrite (ONOO − ) rapidly in 10 mM HEPES buffer at pH 7.4 with high selectivity. It displayed an extraordinary detection limit (9.0 nM). The probe was also employed for the bioimaging of ONOO − in living cells.

Abstract Image The first boronic acid functionalized Hf-based UiO-66 (UiO = University of Oslo) metal–organic framework (MOF) having the ability to detect both extracellular and intracellular peroxynitrite is presented. The Hf-UiO-66-B(OH) 2material ( 1 ) was synthesized under solvothermal conditions from a mixture of HfCl 4and 2-borono-1,4-benzenedicarboxylic acid [H 2BDC–B(OH) 2] ligand in DMF in the presence of formic acid (modulator) at 130 °C for 48 h. The desolvated material ( 1′ ) was utilized as a fluorescent turn-on probe for the rapid sensing of extracellular peroxynitrite (ONOO – ) under conditions mimicking those of biological medium (10 mM HEPES buffer, pH 7.4). Selective sensing of ONOO – over other ROS/RNS was also achieved by 1′. The oxidative cleavage of attached boronic acid groups forming corresponding hydroxy-functionalized ligands can be accounted for the fluorescent increment phenomenon in the presence of ONOO –. The probe showed extraordinary sensitivity (detection limit = 9.0 nM) toward ONOO – in 10 mM HEPES buffer at pH 7.4. Probe-loaded cells did not exhibit cytotoxicity and morphological deformities. It is remarkable that the probe inside the cells responded toward the peroxynitrite solution to give an intense blue fluorescent signal. The fluorescence microscopy study with J774A.1 macrophage cells unambiguously demonstrated that probe 1′ is suitable to image peroxynitrite in living cells.

For years, archaeologists have wondered why the Norse settled on Greenland's inhospitable, ice-bound edges at the end of the first millennium A.D. The living certainly wasn't easy-so why did they stay, and how did they survive?

Clues to the mystery of why Viking colonies in Greenland flourished and fell have been found in the DNA of medieval walrus bones housed in more than a dozen European museums.

© Christian Koch Madsen via Associated Press This 2009 photo provided by Christian Koch Madsen shows the ruins of the Hvalsey Church, part of an abandoned Viking colony, in southern Greenland.

Collapsing ivory market, not climate change, may have doomed Greenland settlements

Clues to the mystery of why Viking colonies in Greenland flourished and fell have been found in the DNA of medieval walrus bones housed in more than a dozen European museums.

The Icelandic Sagas tell of Erik the Red: exiled for murder in the late 10th century he fled to southwest Greenland, establishing its first Norse settlement.

A new study reveals how the Norse eked out a good life on the icy island by cornering the market in this exotic wildlife product.

The Icelandic Sagas tell of Erik the Red: exiled for murder in the late 10th century he fled to southwest Greenland, establishing its first Norse settlement.

Caster Semenya of South Africa celebrates winning the 800m final at the Commonwealth Games.

This is an example of an elaborately-carved ecclesiastical walrus ivory plaque from the beginning of the medieval walrus ivory trade, featuring the figure of Christ, together with St Mary and St Peter, and believed to date from the 10th or 11th century. Found in North Elmham, Norfolk, UK, in the 19th century, and currently exhibited in the University of Cambridge s Museum of Archaeology and Anthropology.

An ‘overreliance on a single commodity’ may have led to the downfall of Erik the Red’s Greenland colony

New DNA analysis reveals that, before their mysterious disappearance, the Norse colonies of Greenland had a 'near monopoly'on Europe's walrus ivory supply. An overreliance on this trade may have contributed to Norse Greenland's collapse when the medieval market declined.

Collapsing ivory market, not climate change, may have doomed Greenland settlements

This 2009 photo provided by Christian Koch Madsen shows the ruins of the Hvalsey Church, part of an abandoned Viking colony, in southern Greenland. For almost five hundred years, the Norse descendants of Erik the Red built churches and manor homes and expanded their settlements on the icy fringes of European civilization.

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

The collapse in the walrus tusk trade triggered an economic crisis for early Viking colonists in Greenland that led to the downfall of its settlements and churches, according to new research.

This 2009 photo provided by Christian Koch Madsen shows the ruins of the Hvalsey Church, part of an abandoned Viking colony, in southern Greenland. For almost five hundred years, the Norse descendants of Erik the Red built churches and manor homes and expanded their settlements on the icy fringes of European civilization.

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

WASHINGTON – Clues to the mystery of why Viking colonies in Greenland flourished and fell have been found in the DNA of medieval walrus bones housed in more than a dozen European museums.

WASHINGTON – Clues to the mystery of why Viking colonies in Greenland flourished and fell have been found in the DNA of medieval walrus bones housed in more than a dozen European museums.

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Photo: AP Walrus bones provide clues to mystery of lost Viking colony

Photo: AP Walrus bones provide clues to mystery of lost Viking colony

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Photo: AP Walrus bones provide clues to mystery of lost Viking colony

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

Photo: AP Walrus bones provide clues to mystery of lost Viking colony

Author: Associated Press Published: 7:45 AM EDT August 8, 2018 Updated: 7:55 AM EDT August 8, 2018

This 2009 photo provided by Christian Koch Madsen shows the ruins of the Hvalsey Church, part of an abandoned Viking colony, in southern Greenland. For almost five hundred years, the Norse descendants of Erik the Red built churches and manor homes and expanded their settlements on the icy fringes of European civilization.