Xia Sheng

PhD Student
Image of Xia Sheng
Norwegian version of this page
Room 3603
Visiting address Blindernveien 31 0316 OSLO
Postal address Postboks 1066 Blindern 0316 OSLO


The highly prostate enriched STAMP1 protein, previously identified in our lab, belongs to a family of six transmembrane proteins with a conserved oxido-reductase domain. We previously found that STAMP1 is critical for prostate cancer cell growth and survival in vitro and in vivo. The goal of my project is to characterize the functional role of STAMP1 in prostate cancer progression. I am especially interested in as to how STAMP1 affects the critical signaling pathways in prostate cancer cells.


  • Zhang, Tingting; Li, Ningning; Sun, Chaoyang; Jin, Yang & Sheng, Xia (2020). MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?. EMBO Molecular Medicine.  ISSN 1757-4676.  12(5), s 1- 12 . doi: 10.15252/emmm.201911845
  • Sheng, Xia; Nenseth, Hatice Zeynep; Qu, Su; Kuzu, Ömer Faruk; Frahnow, Turid; Simon, Lukas; Greene, Stephanie; Zeng, Qingping; Fazli, Ladan; Rennie, Paul S.; Mills, Ian Geoffrey; Danielsen, Håvard Emil; Theis, Fabian; Patterson, John B.; Jin, Yang & Saatcioglu, Fahri (2019). IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nature Communications.  ISSN 2041-1723.  10:323, s 1- 12 . doi: 10.1038/s41467-018-08152-3 Full text in Research Archive.
  • Wang, Yu; Wang, Kai; Jin, Yang & Sheng, Xia (2019). Endoplasmic reticulum proteostasis control and gastric cancer. Cancer Letters.  ISSN 0304-3835.  449, s 263- 271 . doi: 10.1016/j.canlet.2019.01.034
  • Wang, Yu; Wang, Ziyi; Yu, Wenyang; Sheng, Xia; Zhang, Haolin; Han, Yingying; Yuan, Zhengrong & Weng, Qiang (2018). Seasonal expressions of androgen receptor, estrogen receptors and cytochrome P450 aromatase in the uteri of the wild daurian ground squirrels (Spermophilus dauricus). European journal of histochemistry.  ISSN 1121-760X.  62(1), s 75- 82 . doi: 10.4081/ejh.2018.2889
  • Winje, Ivan; Sheng, Xia; Hansson, Kenth-Arne; Solbrå, Andreas Våvang; Tennøe, Simen; Saatcioglu, Fahri; Bruusgaard, Jo C. & Gundersen, Kristian (2018). Cachexia does not induce loss of myonuclei or muscle fibres during xenografted prostate cancer in mice. Acta Physiologica.  ISSN 1748-1708.  s 1- 9 . doi: 10.1111/apha.13204
  • Urbanucci, Alfonso; Barfeld, Stefan Jörg; Kytölä, Ville; Itkonen, Harri; Coleman, Ilsa M.; Vodák, Daniel; Sjöblom, Liisa; Sheng, Xia; Minner, Sarah; Burdelski, Christoph; Kivinummi, Kati K.; Kohvakka, Annika; Kregel, Steven; Takhar, Mandeep; Alshalalfa, Mohammed; Davicioni, Elai; Erho, Nicholas; Lloyd, Paul; Karnes, R. Jeffrey; Ross, Ashley E.; Schaeffer, Edward M.; Vander Griend, Donald J; Knapp, Stefan; Corey, Eva; Feng, Felix Y.; Nelson, Peter S.; Saatcioglu, Fahri; Knudsen, Karen E.; Tammela, Teuvo L.J.; Sauter, Guido; Schlomm, Thorsten; Nykter, Matti; Visakorpi, Tapio & Mills, Ian Geoffrey (2017). Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer. Cell reports.  ISSN 2211-1247.  19(10), s 2045- 2059 . doi: 10.1016/j.celrep.2017.05.049 Full text in Research Archive.
  • Wang, Junjie; Wang, Ying; Zhu, Manyu; Zhang, Fengwei; Sheng, Xia; Zhang, Haolin; Han, Yingying; Yuan, Zhengrong & Weng, Qiang (2017). Seasonal expression of luteinizing hormone receptor and follicle stimulating hormone receptor in testes of the wild ground squirrels (Citellus dauricus Brandt). Acta Histochemica.  ISSN 0065-1281.  119(7), s 727- 732 . doi: 10.1016/j.acthis.2017.09.004
  • Xi, Liqin; Liu, Yuning; Tang, Zeqi; Sheng, Xia; Zhang, Haolin; Weng, Qiang & Xu, Meiyu (2017). Expression of leptin receptor in the oviduct of Chinese brown frog (Rana dybowskii). American Journal of Physiology. Regulatory Integrative and Comparative Physiology.  ISSN 0363-6119.  312(6), s R912- R918 . doi: 10.1152/ajpregu.00020.2017
  • Zhang, Fengwei; Liu, Qian; Wang, Ziyi; Xie, Wenqian; Sheng, Xia; Zhang, Haolin; Yuan, Zhengrong; Han, Yingying & Weng, Qiang (2017). Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus). Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-16973-3
  • Zhang, Fengwei; Wang, Yu; Han, Wentao; Wang, Junjie; Zhang, Haolin; Sheng, Xia; Yuan, Zhengrong; Weng, Qiang & Han, Yingying (2017). Seasonal changes of androgen receptor, estrogen receptors and aromatase expression in the hippocampus of the wild male ground squirrels (Citellus dauricus Brandt). General and Comparative Endocrinology.  ISSN 0016-6480.  249, s 93- 100 . doi: 10.1016/j.ygcen.2017.05.009
  • Sikkeland, Jørgen; Sheng, Xia; Jin, Yang & Saatcioglu, Fahri (2016). STAMPing at the crossroads of normal physiology and disease states. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  425, s 26- 36 . doi: 10.1016/j.mce.2016.02.013
  • Storm, Margrethe Larsdatter; Sheng, Xia; Arnoldussen, Yke Jildouw & Saatcioglu, Fahri (2016). Prostate cancer and the unfolded protein response. OncoTarget.  ISSN 1949-2553.  7(33), s 54051- 54066 . doi: 10.18632/oncotarget.9912 Full text in Research Archive. Show summary
  • Zhou, Jiao; Li, Juan; Wang, Rong; Sheng, Xia; Zong, Shixiang; Weng, Qiang & Luo, Youqing (2016). Ecdysteroid titers and expression of Halloween genes and ecdysteroid receptor in relation to overwintering and the long larval phase in the seabuckthorn carpenterworm, Holcocerus hippophaecolus. Entomologia Experimentalis et Applicata.  ISSN 0013-8703.  160(2), s 133- 146 . doi: 10.1111/eea.12472
  • Jin, Yang; Ling, Wang; Qu, Su; Sheng, Xia; Kristian, Alexandr; Mælandsmo, Gunhild; Pällmann, Nora; Yuca, Erkan; Tekedereli, Ibrahim; Gorgulu, Kivanc; Alpay, Neslihan; Sood, Anil K.; Lopez-Berestein, Gabriel; Fazli, Ladan; Rennie, Paul S.; Risberg, Bjørn Åke; Wæhre, Haakon; Danielsen, Håvard Emil; Ozpolat, Bulent & Saatcioglu, Fahri (2015). STAMP2 increases oxidative stress and is critical for prostate cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  7(3), s 315- 331 . doi: 10.15252/emmm.201404181 Full text in Research Archive.
  • Sheng, Xia; Arnoldussen, Yke Jildouw; Storm, Margrethe Larsdatter; Tesikova, Martina; Nenseth, Hatice Zeynep; Zhao, Sen; Fazli, Ladan; Rennie, Paul S.; Risberg, Bjørn Åke; Wæhre, Haakon; Danielsen, Håvard Emil; Mills, Ian Geoffrey; Jin, Yang; Hotamisligil, Gökhan S & Saatcioglu, Fahri (2015). Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  7(6), s 788- 801 . doi: 10.15252/emmm.201404509 Full text in Research Archive. Show summary
  • Li, Juan; Zhou, Jiao; Sun, Rongbo; Zhang, Haolin; Zong, Shixiang; Luo, Youqing; Sheng, Xia & Weng, Qiang (2013). cDNA CLONING AND SEQUENCE DETERMINATION OF THE PHEROMONE BIOSYNTHESIS ACTIVATING NEUROPEPTIDE FROM THE SEABUCKTHORN CARPENTERWORM, Holcocerus hippophaecolus (LEPIDOPTERA: COSSIDAE). Archives of Insect Biochemistry and Physiology.  ISSN 0739-4462.  82(4), s 183- 195 . doi: 10.1002/arch.21084

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Published June 7, 2016 12:28 PM