Reidun Sirevåg

Professor emerita

Academic Interests

I have an interest in the general biology of microorganisms.

I have always been interested in the physiology, biochemistry and molecular biology of various phototrophic bacteria. The recent years I have especially worked with proteins from phototrophic bacteria living at a high temperature in hot springs. I have also worked on more applied projects in industrial collaborations, to develop rapid molecular methods to detect bacteria in drinking water.

 

Teaching

MBV3060- General microbiology

MBV4130- The biology of the prokaryotes

 

Employment history

Adjunct, Ris gymnas 1961-1966

Scientific assistant, UiO  1966-1972

Associate Professor, UiO 1977-1988

Professor of microbiology, UiO 1988-2009

General secretary of The Norwegian Academy of Science and Letters 2001-2009

 

Higher education

Cand.mag. natural sciences UiO, 1961

M.Sc. in microbiology from Vassar College, N.Y,  1968. Thesis about sporulation in Bacillus.

Dr. philos. UiO  1977. Thesis ”Carbon metabolism in Chlorobium thiosulfatophilum”.

Sabbatical at Harvard University, 1970/71

Sabbatical at UCSB, Santa Barbara, California 1986/87

Sabbatical at UCSB, Santa Barbara, California 2002

 

Appointments

Member of the board of Centre for Ecological and Evolutionary Syntethsis (CEES), UiO

Member of the board of the basic science programme VISTA (financed by Statoil in a collaboration with The Norwegian Academy of Science and Letters

Member of the prize committee for a good learning environment, UiO

Collaborations

Presently I collaborate with groups at the Norwegian Institute of Public Health in a project concerning Legionella.

 

Publications

  • Anglès d'Auriac, Marc B & Sirevåg, Reidun (2018). Multiplex PCR for the simultaneous detection of the Enterobacterial gene wecA, the Shiga Toxin genes (stx1 and stx2) and the Intimin gene (eae). BMC Research Notes.  ISSN 1756-0500.  11(360), s 1- 7 . doi: 10.1186/s13104-018-3457-8 Full text in Research Archive. Show summary
  • Lærum, Ole Didrik; Helsvig, Kim Gunnar & Sirevåg, Reidun (2009). The Norwegian Academy of Science and Letters: current revival of a time-honoured institution. International Journal of Technology Management.  ISSN 0267-5730.  46(1-2), s 27- 37
  • Nederbragt, Alexander J; Balasingham, Anusha; Sirevåg, Reidun; Utkilen, Hans Chr.; Jakobsen, Kjetill S & Anderson-Glenna, Mary (2008). Multiple-locus variable-number tandem repeat analysis of Legionella pneumophila using multi-colored capillary electrophoresis. Journal of Microbiological Methods.  ISSN 0167-7012.  73(2), s 111- 117 . doi: 10.1016/j.mimet.2008.02.007
  • Gulliksen, A; Solli, Lars Anders; Drese, KS; Karlsen, F; Sorensen, O; Karlsen, F; Rogne, H; Hovig, Johannes Eivind; Rogne, H; Hovig, E; Sirevåg, Reidun & Sirevag, R (2005). Parallel nanoliter detection of cancer markers using polymer microchips. Lab on a Chip.  ISSN 1473-0197.  5
  • Gulliksen, Anja; Solli, Lars Anders; Drese, Klaus Stefan; Sørensen, Olaf; Karlsen, Frank; Rogne, Henrik; Hovig, Eivind & Sirevåg, Reidun (2005). Parallel nanoliter detection of cancer markers using polymer microchips. Lab on a Chip.  ISSN 1473-0197.  5(4), s 416- 420 Show summary
  • Eijsink, Vincent; Bjørk, Alexandra; Gåseidnes, Sigrid; Sirevåg, Reidun; Synstad, Bjørnar; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability. Journal of Biotechnology.  ISSN 0168-1656.  113, s 105- 120
  • Gulliksen, A; Solli, Christian; Solli, Lars; Karlsen, F; Rogne, H; Hovig, E; Hovig, Eivind; Nordstrøm, Trine; Nordstrom, T; Sirevag, R & Sirevåg, Reidun (2004). Real-time nucleic acid sequence-based amplification in nanoliter volumes. Analytical Chemistry.  ISSN 0003-2700.  76, s 9- 14
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Sirevåg, Reidun & Eijsink, Vincent (2004). Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  341, s 1215- 1226
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2004). Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  341, s 1215- 1226
  • Eijsink, Vincent; Gåseidnes, Sigrid; Synstad, Bjørnar; Bjørk, Alexandra; Sirevåg, Reidun; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability. Journal of Biotechnology.  ISSN 0168-1656.  113, s 105- 120
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  334, s 811- 821
  • Bjørk, Alexandra; Mantzilas, Dimitrios; Sirevåg, Reidun & Eijsink, Vincent G. H. (2003). Electrostatic interactions across the dimer-dimer interface contribute to the pH-dependent stability of a tetrameric malate dehydrogenase. FEBS Letters.  ISSN 0014-5793.  553, s 423- 426
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2003). Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface. ?.  334, s 811- 821
  • Bjørk, Alexandra; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2003). A network of salt bridges contributes to the pH-dependent stability and oligomerization state of a tetrameric malate dehydrogenase. FEBS Letters.  ISSN 0014-5793.  553, s 423- 426
  • Dalhus, Bjørn; Saarinen, Markuu; Sauer, Uwe H.; Eker, Per; Johansson, Kenth; Karlsson, Andreas; Ramaswamy, S.; Bjørk, Alexandra; Synstad, Bjørnar; Naterstad, Kristine; Sirevåg, Reidun & Eklund, Hans (2002). Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases. Journal of Molecular Biology.  ISSN 0022-2836.  318(3), s 707- 721 . doi: 10.1016/S0022-2836(02)00050-5 Show summary
  • Anglès d'Auriac, Marc B; Roberts, Hildegarde; Shaw, Terri; Sirevåg, Reidun; Hermansen, Leonila Fajardo & Berg, James D (2000). Field Evaluation of a Semiautomated Method for Rapid and Simple Analysis of Recreational Water Microbiological Quality. Applied and Environmental Microbiology.  ISSN 0099-2240.  66(10), s 4401- 4407 . doi: 10.1128/AEM.66.10.4401-4407.2000 Show summary
  • Kolstø, Anne-Brit; Naterstad, K. & Sirevåg, Reidun (1995). Physical map of the genome of the green phototrophic bacterium Chlorobium tepidum. Journal of Bacteriology.  ISSN 0021-9193.  (177), s 5480- 5484
  • Naterstad, K.; Kolstø, Anne-Brit & Sirevåg, Reidun (1995). Physical map of the genome of the green phototropic bacterium Chlorobium tepidum. Journal of Bacteriology.  ISSN 0021-9193.  177, s 5480- 5484

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  • Østerud, Øyvind; Sirevåg, Reidun & Lærum, Ole Didrik (red.) (2009). Det Norske Videnskaps-Akademi Årbok 2008. Novus Forlag.  ISBN 9788270995547.  410 s.

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  • Sirevåg, Reidun (2018). Diktatur kan være nyttig. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Sirevåg, Reidun (2018). Et bioteknologisk eventyr med store politiske følger. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Buchanan, Bob B.; Sirevåg, Reidun; Fuchs, Georg; Ivanovksy, Ruslan N.; Igarashi, Yasuo; Ishii, Masaharu; Tabita, F. Robert & Berg, Ivan A. (2017). The Arnon-Buchanan cycle; a retrospective, 1966-2016. Photosynthesis Research.  ISSN 0166-8595.  134(2), s 117- 131 . doi: 10.1007/s11120-017-0429-0
  • Helsvig, Kim Gunnar; Sirevåg, Reidun & Lærum, Ole Didrik (2006). Norwegian Academy of Science and Letters. From National Policy to Global Science. Allea Biennial Yearbook.  s 121- 133
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2004). Stabilization of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2004). Stabilization of a tetrameric malate dehydrogenase.
  • Eijsink, Vincent; Bjørk, Alexandra; Gåseidnes, Sigrid; Sirevåg, Reidun; Synstad, Bjørnar; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability.
  • Benestad, Ingun; Ytteborg, Elisabeth; Vanberg, Christin & Sirevåg, Reidun (2003). Two operons for chaperones in Chloroflexus aurantiacus.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Malate dehydrogenase from mesophilic and thermophilic green bacteria.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Structural basis for protein thermostability; analysis of interactions within a protein oligomer and engeneering towards higher thermostability.
  • Bjørk, Alexandra; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2003). Stabilization of tetrameric malate dehydrogenase from Chloroflexus aurantiacus by engineering of an ionic network in the dimer-dimer interface.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). STABILIZATION OF TETRAMERIC MALATE DEHYDROGENASE FROM CHLOROFLEXUS AURANTIACUS BY ENGINEERING AN IONIC NETWORK IN THE DIMER-DIMER INTERFACE.
  • Bjørk, Alexandra; Mantzilas, Dimitrios; Dalhus, Bjørn; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). STABILIZATION OF TETRAMERIC MALATE DEHYDROGENASE FROM CHLOROFLEXUS AURANTIACUS BY ENGINEERING AN IONIC NETWORK IN THE DIMER-DIMER INTERFACE.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eijsink, Vincent G. H.; Mantzilas, Dimitrios & Sirevåg, Reidun (2002). Analysis of an ionic network within a protein oligomer and engeneering towards higher thermostability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Sirevåg, Reidun & Eklund, Hans (2002). Structural basis for protein thermostability - crystal structures of thermostable tetrameric malate dehydrogenases.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2002). Stabilization of tetrameric malate dehydrogenase from Chloroflexus aurantiacus by engineering an ionic network in the dimer-dimer interface.
  • Eijsink, Vincent; Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris & Sirevåg, Reidun (2002). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2001). Mutations at the dimer-dimer interface in tetrameric malate dehydrogenase from Chloroflexus aurantiacus have large effects on thermal stability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eklund, Hans & Sirevåg, Reidun (2001). Crystal structures of MDHs from thermophilic bacteria: structural basis for protein thermostability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Sirevåg, Reidun & Eklund, Hans (2001). Crystal structure of MDHs from thermophilic bacteria - structural basis for thermophilic protein stability.
  • Vanberg, Christin; Bjørk, Alexandra & Sirevåg, Reidun (2001). The moderate thermophilic green gliding bacterium Chloroflexus aurantiacus contains to alleles for chaperonins.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2001). Mutations at the dimer-dimer interface in tetrameric malate dehydrogenase from Chloroflexus aurantiacus have large effects on thermal stability.
  • Bjørk, Alexandra; Eijsink, Vincent G. H. & Sirevåg, Reidun (2000). Thermostability of tetrameric malate dehydrogenase from the green, gliding bacterium Chloroflexus aurantiacus.
  • Vanberg, Christin; Bjørk, Alexandra & Sirevåg, Reidun (2000). Molecular chaperones from the moderate thermophilic, green gliding bacterium Chloroflexus aurantiacus.
  • Bjørk, Alexandra; Molden, Tor; Torgunrud, Annette & Sirevåg, Reidun (1999). Thermostable malate dehydrogenases from phototrophic bacteria. Show summary
  • Karlsen, Frank; Andreassen, Trine-Merethe; Rabone, Marian; Skrodenyte, Vesta; Sirevåg, Reidun; Eckner, Karl; D´Auriac, Marc Angles; Berg, James; Bergseth, Steinar & Charnock, Colin (1999). Development of molecular methods for rapid detection of coliform bacteria in water. Show summary
  • Molden, Tor; Bjørk, Alexandra; Tooming, Ave & Sirevåg, Reidun (1999). Thermostability in Chloroflexus aurantiacus. Show summary
  • Molden, Tor; Bjørk, Alexandra; Tooming, Ave & Sirevåg, Reidun (1999). Thermostability in Chloroflexus aurantiacus. Show summary
  • Tooming, Ave & Sirevåg, Reidun (1999). Induction of molecular chaperones in the thermophilic green bacterium Chloroflexus aurantiacus. Show summary

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Published Mar. 23, 2011 11:26 PM - Last modified Nov. 23, 2018 2:13 PM