Abstract:
In this talk I'll try to introduce a new computational approach to examine allele specific effects in hybrids using NGS data. This new approach is subsequently used to understand transcriptomic as well as epigenomic changes of two heterotic tomato crosses. To achieve this, the genomes of the three used tomato variants were de novo assembled, annotated and correlated using an improved orthology mapping. Insights on epigenetic observations from this study will be presented including DNA-methylation and small-RNAs.