A living muscle cell of a mouse injected with a oligonucleotide (green) and dextran (red). Notice the uptake of DNA in the nuclei and the gathering of 'fundamental' nuclei by the synapsis where the acetylcholin receptors are marked in red. The fiber diameter is ca. 30µm.
Our main research interest involves how activities in the neural system influences synapses and target cells. This subject has relevance to neurobiology and health issues associated with physical activity. In addition to standard molecular techniques, our groups specializes in microscopy and in vivo imaging of single cells. We have developed a technique in which single cells are made transgenic in intact animals by injecting DNA expression vectors intra cellular.
New study by the Gundersen lab demonstrates that brief exposure to performance-enhancing drugs may have permanent effects.
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