Geir Åge Løset

Bilde av Geir Åge Løset
English version of this page
Brukernavn
Besøksadresse Blindernveien 31 None 0371 OSLO
Postadresse Postboks 1066 Blindern 0316 OSLO

Publikasjoner

  • Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Neumann, Ralf Stefan; Bjerregaard-Andersen, Kaare; Nilssen, Nicolay Rustad; Sollid, Ludvig Magne; Sandlie, Inger & Løset, Geir Åge (2018). Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system. PLoS ONE.  ISSN 1932-6203.  13(4), s e0195868 . doi: 10.1371/journal.pone.0195868 Vis sammendrag
  • Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva; Neumann, Ralf Stefan; Bergseng, Elin; Frigstad, Terje; Frick, Rahel; du Pré, Marie Fleur; Dalhus, Bjørn; Lundin, Knut Erik Aslaksen; Qiao, Shuo Wang; Sollid, Ludvig Magne; Sandlie, Inger & Løset, Geir Åge (2017). A TCRα framework–centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions. JCI Insight.  ISSN 2379-3708.  2(17) . doi: 10.1172/jci.insight.95193 Fulltekst i vitenarkiv.
  • Kara, Emrah; Manna, Dipankar; Løset, Geir Åge; Schneider, E L; Craik, C S & Kanse, Sandip (2017). Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates. Thrombosis and Haemostasis.  ISSN 0340-6245. . doi: 10.1160/TH17-02-0081 Fulltekst i vitenarkiv.
  • Grødeland, Gunnveig; Fredriksen, Agnete; Løset, Geir Åge; Vikse, Elisabeth Lea; Fugger, Lars & Bogen, Bjarne (2016). Antigen targeting to human HLA Class II molecules increases efficacy of DNA vaccination. Journal of Immunology.  ISSN 0022-1767.  197(9), s 3575- 3585 . doi: 10.4049/jimmunol.1600893
  • Høydahl, Lene Støkken; Nilssen, Nicolay Rustad; Gunnarsen, Kristin Støen; du Pré, Marie Fleur; Iversen, Rasmus; Roos, Norbert; Chen, Xi; Michaelsen, Terje Einar; Sollid, Ludvig Magne; Sandlie, Inger & Løset, Geir Åge (2016). Multivalent pIX phage display selects for distinct and improved antibody properties. Scientific Reports.  ISSN 2045-2322.  6 . doi: 10.1038/srep39066 Fulltekst i vitenarkiv.
  • Løset, Geir Åge; Berntzen, Gøril; Frigstad, Terje; Pollmann, Sylvie; Gunnarsen, Kristin Støen & Sandlie, Inger (2015). Phage display engineered T cell receptors as tools for the study of tumor peptide–MHC interactions. Frontiers in Oncology.  ISSN 2234-943X. . doi: 10.3389/fonc.2014.00378 Fulltekst i vitenarkiv.
  • Frigstad, Terje; Løset, Geir Åge; Sandlie, Inger & Bogen, Bjarne (2013). A Public T cell Receptor Recognized by a MonoclonalAntibody Specific for the D-J Junction of the b-chain. Scandinavian Journal of Immunology.  ISSN 0300-9475.  (78), s 345- 351 . doi: 10.1111/sji.12098
  • Gunnarsen, Kristin Støen; Kristinsson, Solveig Gunn; Justesen, Sune; Frigstad, Terje; Buus, Søren; Bogen, Bjarne; Sandlie, Inger & Løset, Geir Åge (2013). Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display. Scientific Reports.  ISSN 2045-2322.  3 . doi: 10.1038/srep01162 Fulltekst i vitenarkiv.
  • Løset, Geir Åge & Sandlie, Inger (2012). Next generation phage display by use of pVII and pIX as display scaffolds. Methods.  ISSN 1046-2023.  58(1), s 40- 46 . doi: 10.1016/j.ymeth.2012.07.005
  • Nilssen, Nicolay Rustad; Frigstad, Terje; Pollmann, Sylvie; Roos, Norbert; Bogen, Bjarne; Sandlie, Inger & Løset, Geir Åge (2012). DeltaPhage-a novel helper phage for high-valence pIX phagemid display. Nucleic Acids Research.  ISSN 0305-1048.  40(16) . doi: 10.1093/nar/gks341 Fulltekst i vitenarkiv.
  • Løset, Geir Åge; Bogen, Bjarne & Sandlie, Inger (2011). Expanding the Versatility of Phage Display I: Efficient Display of Peptide-Tags on Protein VII of the Filamentous Phage. PLoS ONE.  ISSN 1932-6203.  6(2) . doi: 10.1371/journal.pone.0014702 Fulltekst i vitenarkiv.
  • Løset, Geir Åge; Roos, Norbert; Bogen, Bjarne & Sandlie, Inger (2011). Expanding the Versatility of Phage Display II: Improved Affinity Selection of Folded Domains on Protein VII and IX of the Filamentous Phage. PLoS ONE.  ISSN 1932-6203.  6(2) . doi: 10.1371/journal.pone.0017433 Fulltekst i vitenarkiv.
  • Qiao, Shuo Wang; Raki, Melinda; Gunnarsen, Kristin Støen; Løset, Geir Åge; Lundin, Knut E A; Sandlie, Inger & Sollid, Ludvig Magne (2011). Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease. Journal of Immunology.  ISSN 0022-1767.  187(6), s 3064- 3071 . doi: 10.4049/jimmunol.1101526
  • Wälchli, Sebastien; Løset, Geir Åge; Kumari, Shraddha; Johansen, Jorunn; Yang, Weiwen; Sandlie, Inger & Olweus, Johanna (2011). A Practical Approach to T-Cell Receptor Cloning and Expression. PLoS ONE.  ISSN 1932-6203.  6(11) . doi: 10.1371/journal.pone.0027930 Fulltekst i vitenarkiv.
  • Gunnarsen, Kristin Støen; Lunde, Elin; Kristiansen, Per Eugen; Bogen, Bjarne; Sandlie, Inger & Løset, Geir Åge (2010). Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA. BMC Biotechnology.  ISSN 1472-6750.  10 . doi: 10.1186/1472-6750-10-8 Fulltekst i vitenarkiv.
  • Lunde, Elin; Løset, Geir Åge; Bogen, Bjarne & Sandlie, Inger (2010). Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins. BMC Biotechnology.  ISSN 1472-6750.  10 . doi: 10.1186/1472-6750-10-61 Fulltekst i vitenarkiv.
  • Løset, Geir Åge; Kristinsson, Solveig Gunn & Sandlie, Inger (2008). Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pill phenotype. BioTechniques.  ISSN 0736-6205.  44(4), s 551- 554 . doi: 10.2144/000112724 Vis sammendrag
  • Løset, Geir Åge; Lunde, Elin; Bogen, Bjarne; Brekke, OH & Sandlie, Inger (2007). Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance. Protein Engineering Design & Selection.  ISSN 1741-0126.  20, s 461- 472 . doi: 10.1093/protein/gzm044
  • Løset, Geir Åge; Løbersli, Inger; Kavlie, Anita; Stacy, John Eric; Borgen, Tine; Kausmally, Louise; Hvattum, Else; Simonsen, Bjørg; Befring Hovda, Maria & Brekke, Ole Henrik (2005). Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire. JIM - Journal of Immunological Methods.  ISSN 0022-1759.  299(1-2), s 47- 62 . doi: 10.1016/j.jim.2005.01.014
  • Løset, Geir Åge; Løbersli, Inger; Kavlie, Anita; Stacy, John; Borgen, Tine; Kausmally, Louise; Hvattum, Else; Hovda, Maria & Brekke, Ole Henrik (2005). Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repetoire. JIM - Journal of Immunological Methods.  ISSN 0022-1759.  299(01.feb), s 47- 62
  • Reiersen, Herald; Løbersli, Inger; Løset, Geir Åge; Hvattum, Else; Simonsen, Bjørg; Stacy, John Eric; McGregor, Duncan; FitzGerald, Kevin; Welschof, Martin; Brekke, Ole Henrik & Marvik, Ole Jørgen (2005). Covalent antibody display--an in vitro antibody-DNA library selection system. Nucleic Acids Research.  ISSN 0305-1048.  33(1) . doi: 10.1093/nar/gni010
  • Løset, Geir Åge; Roux, K.H.; Zhu, P.; Michaelsen, Terje Einar & Sandlie, Inger (2004). Differential segmental flexibility and reach dictate the antigen binding mode of chimeric IgD and IgM: Implications for the function of the B cell receptor. Journal of Immunology.  ISSN 0022-1767.  172, s 2925- 2934
  • Brekke, Ole Henrik & Løset, Geir Åge (2003). New technologies in therapeutic antibody development. Current opinion in pharmacology (Print).  ISSN 1471-4892.  3(5), s 544- 550 . doi: 10.1016/j.coph.2003.05.002
  • Thommesen, John Einar; Michaelsen, Terje Einar; Løset, Geir Åge; Sandlie, Inger & Brekke, Ole Henrik (2000). Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation. Molecular Immunology.  ISSN 0161-5890.  37(16), s 995- 1004

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  • Løset, Geir Åge; Mousavi, Seyed A. & Berg, Trond (2008). Sinusoidal liver cells and liver tolerance. Transworld Research Network.  ISBN 8178953641.  11 s.

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  • Johannesen, Hedda; Hoås Mykland, Helene; Heggelund, Julie Elisabeth; Bjerregaard-Andersen, Kaare; Løset, Geir Åge & Krengel, Ute (2018). An anti-ganglioside scFv for cancer therapies.
  • Kara, Emrah; Manna, Dipankar; Løset, Geir Åge; Schneider, Eric L.; Craik, Charles S. & Kanse, Sandip (2017). Analysis of the Substrate Specificity of Factor VII Activating Protease (FSAP) and Design of a Specific and Sensitive Peptide Substrate. Res Pract Thromb Haemost.  s 560- 560 . doi: 10.1002/rth2.12012
  • Mandecki, W.; Goldman, E.; Sandlie, Inger & Løset, Geir Åge (2015). Phage Display and Selection of Protein Ligands, In Emanuel Goldman & Laurence Green (ed.),  Practical Handbook of Microbiology, Third Edition.  CRC Press.  ISBN 9781466587397.  Chapter 9.  s 101 - 114
  • Johannesen, Hedda; Bousquet, Paula; Løset, Geir Åge & Krengel, Ute (2014). L`ASSASSINA PROTEIN THAT SPECIFICALLY KILLS TUMOUR CELLS.
  • Johannesen, Hedda; Krengel, Ute; Løset, Geir Åge & Bousquet, Paula (2014). The Assassin - Recombinant single-chain Fv production of the anti-tumour antibody 14F7.
  • Gunnarsen, Kristin Støen; Kristinsson, Solveig Gunn; Bogen, Bjarne; Sandlie, Inger & Løset, Geir Åge (2011). Thermostability Engineering of a Soluble Single Chain T Cell Receptor (scTCR) Using Phage Display. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 352- 352
  • Høydahl, Lene Støkken; Neumann, Ralf Stefan; Qiao, Shuo Wang; Sollid, Ludvig Magne; Sandlie, Inger & Løset, Geir Åge (2011). Development of a High Affinity TCR Reagent by Phage Display to Study Antigen Presentation in Celiac Disease. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 372- 372
  • Qiao, Shuo Wang; Raki, Melinda; Gunnarsen, Kristin Støen; Løset, Geir Åge; Sandlie, Inger & Sollid, Ludvig Magne (2011). Post-Translational Modification of Gluten Shapes the T Cell Response in Coeliac Disease by Direct Interaction with the T Cell Receptor. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 356- 356
  • Qiao, Shuo Wang; Raki, Melinda; Løset, Geir Åge; Sandlie, Inger & Sollid, Ludvig Magne (2010). TCR Vbeta Bias and Semi-Public T Cell Responses In DQ2-Gliadin-Alpha-II Specific T Cells From Coeliac Disease Patients. Scandinavian Journal of Immunology.  ISSN 0300-9475.  71(6), s 511- +
  • Gunnarsen, Kristin Støen; Kristinsson, Solveig Gunn; Bogen, Bjarne; Sandlie, Inger & Løset, Geir Åge (2009). Thermostability engineering of a soluble single chain T cell receptor using phage display.
  • Løset, Geir Åge; Lunde, Elin & Sandlie, Inger (2007). Soluble T cell receptors. Not quite like antibodies. NBS-nytt.  ISSN 0801-3535.  (3), s 14- 17
  • Løset, Geir Åge (2005). Antibody and T cell receptor engineering: Mechanistic studies and biotechnological applications. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 482.
  • Flobakk, Morten; Løset, Geir Åge; Rosenhave, Ellen Maryann; Sandlie, Inger; Aalen, Reidunn B.; Blomhoff, Heidi Kiil & Havnes, Jarle (2004). PBL på grunnkurset i cellebiologi og genetikk på Institutt for molekylær Biovitenskap. NBS-nytt.  ISSN 0801-3535.  (4), s 20- 26
  • Løset, Geir Åge (2000). A comparison of the antigen binding ability of antibodies characteristic of the primary immune respons.

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Publisert 4. nov. 2010 14:44 - Sist endret 29. mars 2011 13:47