Jedrzej Mieczyslaw Malecki

Bilde av Jedrzej Mieczyslaw Malecki
English version of this page
Mobiltelefon +47 99 47 91 07
Treffetider Mon-Fre, 8:30-16:00
Brukernavn
Besøksadresse Blindernveien 31 0371 Oslo
Postadresse Postboks 1066 Blindern 0316 Oslo

Faglige interesser

Her kan du skrive om faglige interesser.

Undervisning

<Lenke til studieprogram/emne>
<Lenke til studieprogram/emne>
...

Bakgrunn

Kort om tidligere arbeidserfaring og utdanning

Priser

<Navn og eventuelt lenke til pris 1>
<Navn og eventuelt lenke til pris 2>
...

Verv

<Navn og eventuelt lenke til verv 1>
<Navn og eventuelt lenke til verv 2>
...

Samarbeid

 

Emneord: Biokjemi, Molekylærbiologi

Publikasjoner

  • Davydova, Erna; Shimazu, Tadahiro; Schuhmacher, Maren Kirstin; Jakobsson, Magnus E.; Willemen, Hanneke L.D.M. & Liu, Tongri [Vis alle 28 forfattere av denne artikkelen] (2021). The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes. Nature Communications. ISSN 2041-1723. 12:891, s. 1–14. doi: 10.1038/s41467-020-20670-7. Fulltekst i vitenarkiv
  • Malecki, Jedrzej Mieczyslaw; O'Donohue, Marie-Francoise; Kim, Yeji; Jakobsson, Magnus; Gessa, Luca & Pinto, Rita [Vis alle 14 forfattere av denne artikkelen] (2021). Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function. Nucleic Acids Research (NAR). ISSN 0305-1048. 49(6), s. 3185–3203. doi: 10.1093/nar/gkab088. Fulltekst i vitenarkiv
  • Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders & Eijkelkamp, Niels [Vis alle 7 forfattere av denne artikkelen] (2019). Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration . Journal of Biological Chemistry. ISSN 0021-9258. 294(31), s. 11654–11664. doi: 10.1074/jbc.RA119.009045.
  • Pinto, Rita; Vågbø, Cathrine Broberg; Jakobsson, Magnus; Yeji, Kim; Baltissen, Marijke P & O'Donohue, Marie-Francoise [Vis alle 16 forfattere av denne artikkelen] (2019). The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids Research (NAR). ISSN 0305-1048. 48(2), s. 830–846. doi: 10.1093/nar/gkz1147. Fulltekst i vitenarkiv
  • Malecki, Jedrzej Mieczyslaw; Willemen, Hanneke L.D.M.; Pinto, Rita; Ho, Angela Yeuan Yen; Moen, Anders & Kjønstad, Ingrid Fadum [Vis alle 10 forfattere av denne artikkelen] (2018). Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase. Journal of Biological Chemistry. ISSN 0021-9258. 294(4), s. 1128–1141. doi: 10.1074/jbc.RA118.005473.
  • Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw & Falnes, Pål Øystein (2018). Regulation of eukaryotic elongation factor 1 alpha (eEF1A) by dynamic lysine methylation. RNA Biology. ISSN 1547-6286. 15(3), s. 314–319. doi: 10.1080/15476286.2018.1440875.
  • Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Halabelian, Levon; Nilges, Benedikt S.; Pinto, Rita & Kudithipudi, Srikanth [Vis alle 14 forfattere av denne artikkelen] (2018). The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Nature Communications. ISSN 2041-1723. 9:3411, s. 1–15. doi: 10.1038/s41467-018-05646-y. Fulltekst i vitenarkiv
  • Willemen, Hanneke L.D.M.; Kavelaars, Annemieke; Prado, Judith; Maas, MIrjam; Versteeg, Sabine & Nellissen, Lara J.J. [Vis alle 16 forfattere av denne artikkelen] (2018). Identification of FAM173B as a protein methyltransferase promoting chronic pain. PLoS Biology. ISSN 1544-9173. 16(2). doi: 10.1371/journal.pbio.2003452.
  • Malecki, Jedrzej Mieczyslaw; Jakobsson, Magnus; Ho, Angela Yeuan Yen; Moen, Anders; Rustan, Arild & Falnes, Pål (2017). Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. Journal of Biological Chemistry. ISSN 0021-9258. 292(43), s. 17950–17962. doi: 10.1074/jbc.M117.808451. Fulltekst i vitenarkiv
  • Malecki, Jedrzej Mieczyslaw; Aileni, Vinay Kumar; Ho, Angela Yeuan Yen; Schwarz, Juliane; Moen, Anders & Sørensen, Vigdis [Vis alle 10 forfattere av denne artikkelen] (2017). The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Research (NAR). ISSN 0305-1048. 45(8), s. 4370–4389. doi: 10.1093/nar/gkx002.
  • Jakobsson, Magnus; Malecki, Jedrzej Mieczyslaw; Nilges, Benedikt S.; Moen, Anders; Leidel, Sebastian A. & Falnes, Pål (2017). Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation. Nucleic Acids Research (NAR). ISSN 0305-1048. 45, s. 8239–8254. doi: 10.1093/nar/gkx432. Fulltekst i vitenarkiv
  • Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw & Randen, Ulla [Vis alle 10 forfattere av denne artikkelen] (2017). Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease. British Journal of Haematology. ISSN 0007-1048. 183(5), s. 838–842. doi: 10.1111/bjh.15063.
  • Malecki, Jedrzej Mieczyslaw; Dahl, Helge-Andre; Moen, Anders; Davydova, Erna & Falnes, Pål (2016). The METTL20 homologue from agrobacterium tumefaciens is a dual specificity protein-lysine methyltransferase that targets ribosomal protein L7/L12 and the β subunit of electron transfer flavoprotein (ETFβ). Journal of Biological Chemistry. ISSN 0021-9258. 291(18), s. 9581–9595. doi: 10.1074/jbc.M115.709261.
  • Falnes, Pål; Jakobsson, Magnus; Davydova, Erna; Ho, Angela Yeuan Yen & Malecki, Jedrzej Mieczyslaw (2016). Protein lysine methylation by seven-β-strand methyltransferases. Biochemical Journal. ISSN 0264-6021. 473(14), s. 1995–2009. doi: 10.1042/BCJ20160117.
  • Jakobsson, Magnus; Davydova, Erna; Malecki, Jedrzej Mieczyslaw; Moen, Anders & Falnes, Pål (2015). Saccharomyces cerevisiae eukaryotic elongation factor 1A (eEF1A) is methylated at Lys-390 by a METTL21-like methyltransferase. PLOS ONE. ISSN 1932-6203. 10(6). doi: 10.1371/journal.pone.0131426. Fulltekst i vitenarkiv
  • Malecki, Jedrzej Mieczyslaw; Ho, Angela Yeuan Yen; Moen, Anders; Dahl, Helge-Andre & Falnes, Pål (2015). Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity. Journal of Biological Chemistry. ISSN 0021-9258. 290(1), s. 423–434. doi: 10.1074/jbc.M114.614115.
  • Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Enserink, Jorrit & Jakobsson, Magnus [Vis alle 8 forfattere av denne artikkelen] (2014). Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). Journal of Biological Chemistry. ISSN 0021-9258. 289(44), s. 30499–30510. doi: 10.1074/jbc.M114.601658.
  • Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur & Wesche, Jørgen (2008). Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell. ISSN 1059-1524. 19, s. 3390–3403. doi: 10.1091/mbc.E07-12-1219.
  • Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P & Olsnes, Sjur (2006). FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry. ISSN 0021-9258. 281, s. 11405–11412.
  • Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine & Marcinkowska, Ewa [Vis alle 7 forfattere av denne artikkelen] (2005). Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow). ISSN 0006-2979. 44.
  • Malecki, Jedrzej M.; Wiedlocha, Antoni; Wesche, Jarlis & Olsnes, Sjur (2002). Vesicle transmembrane potential is required for translocation to cytosol externally added FGF-1. EMBO Journal. ISSN 0261-4189. 21, s. 4480–4490.

Se alle arbeider i Cristin

  • Malecka, Agnieszka Maria; Trøen, Gunhild; Delabie, Jan; Malecki, Jedrzej Mieczyslaw; Østlie, Ingunn & Tierens, Anne [Vis alle 9 forfattere av denne artikkelen] (2021). The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels. American Journal of Hematology. ISSN 0361-8609. doi: 10.1002/ajh.26205.
  • Malecka, Agnieszka Maria; Trøen, Gunhild; Tierens, Anne; Østlie, Ingunn; Malecki, Jedrzej Mieczyslaw & Randen, Ulla [Vis alle 9 forfattere av denne artikkelen] (2016). Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity. Haematologica. ISSN 0390-6078. 101(9), s. e361–e364. doi: 10.3324/haematol.2016.146126.

Se alle arbeider i Cristin

Publisert 25. jan. 2016 14:53 - Sist endret 2. mars 2016 19:39