About the NMR Center

The "University of Oslo NMR Center" is located at the Department of Chemistry University of Oslo.

In rooms in the east wing: Ø322, 332, 334, 338 and 340

Short old history

Originally the "Organic NMR" laboratory serviced only the Section for Organic Chemistry at the Department of Chemistry, but has over the years grown into a multi disciplinary NMR Center. As most NMR laboratories for Organic Chemistry the laboratory housed a variety of low field instruments originally. The first spectrometer arriving was a Varian A60 instrument (1966), followed by a Varian HA100-15D instrument (1969), a Jeol FX60 instrument (1974), a Varian XL 300 instrument (1983) and finally a JEOL PMX60 spectrometer (1987). None of these instruments are in use any more. The XL-300 magnet quenched during a large dynamite blast when the Helga Engs Building was constructed at the Blindern campus. The Chemistry building was shaking heavily and it was not possible to charge the XL 300 magnet after that incident. The "Physical NMR" laboratory initially installed a Bruker CXP 200 NMR instrument in 1981. The instrument was upgraded to a DMX 200 system in 1995. The 200 MHz magnet was still alive until mid 2009 when it was shut down - while at the same time SINTEF in Oslo purchased a new solid state Bruker Avance III 500 MHz instrument. A Maran Ultra low field (0.5 T) NMR instrument intended for relaxation and diffusion studies was installed in 2003.  The Varian Gemini 200 instrument from 1989 was owned jointly with the School of Pharmacy, University of Oslo - which owned 25% of the instrument. The gemini 200 instrument was the first instrument to be set up as a self service instrument. Prior to this purchase an engineer was responsible to acquire and plot 1H and 13C spectra for the whole organic chemistry section. This was actually a horrible job for that person, constantly pressed to produce more and more spectra.

Professor Per Kolsaker set up the Gemini 200 instrument for self service and he has probably never got enough credit for this job. Kolsaker´s contribution in this respect to turning the NMR facility into a modern facility has regretfully largely been overlooked.


The University of Oslo NMR Center, to a large extent, still services the NMR needs for Organic Chemistry, but the Center is now also servicing research in;  pharmacy, polymer chemistry, nuclear chemistry, organometallic chemistry, homogeneous catalysis, organic analytical chemistry, inorganic chemistry, medicinal chemistry, material- and nano science, galenic pharmacy, medicinal pharmacy, botany, natural product identification, brain metabolism research, metabolomics studies, algae toxin research, protein structure elucidation and many other research Fields.

Current Instruments

The University of Oslo NMR Center houses eight superconducting NMR instruments: one Bruker AVI 600 equipped with a TCI (1H13C15N) cryo probe and a BACS 60 sample changer, one Bruker DRX 500 instrument, one Bruker AVII 400 instrument with an old magnet originating from Norsk Hydro Hærøya, the magnet production year 1999 with a BACS 120 sample changer and one Bruker AVIII HD 400 instrument installed March 2015, with an old magnet produced in 2001 coming from Astra Zeneca in Sødetalje as well as new electronics. This instrument is equipped with a BACS 60 sample changer.  Additionally we have two walk up instruments to be run manually: one Bruker DPX 300 and one Bruker DPX 200 instrument. In addition the laboratory houses a second 600 MHz NMR instrument, a Bruker AVII 600 instrument with a TCI (1H13C15N) cryo probe where running expenses are shard with School of Pharmacy UiO (22%), the applied science organization the Veterinary Institute (22%), Department of Biosciences UiO (28%) and the Department of Chemistry (28%). This instrument  is dedicated to studies of biomolecules.  The last installation consists of a Bruker AVIII HD 800 instrument equipped with a TCI (1H13C15N) cryo probe. This instrument had three quenches during installation before it  was possible to charge the magnet on Friday November 27th 2015 when the magnetic coil was subcooled to a temperature of 3 Kelvin. A total of 4500 liter of liquid helium was used during all the charging processes.  The total cost for the helium was 450.000 NOK.   


Please contact the scientific leader of the Center if you need to perform NMR experiments. 


Liquid state NMR

Professor Frode Rise

Senior Engineer Dirk Petersen

Published Jan. 13, 2011 3:09 PM - Last modified Dec. 9, 2020 2:01 PM