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Nyman, Anna Armika Tussilago; Aachmann, Finn Lillelund; Rise, Frode; Ballance, Simon; Samuelsen, Anne Berit C.. Structural characterization of a branched (1 → 6)-α-mannan and β-glucans isolated from the fruiting bodies of Cantharellus cibarius. Carbohydrate Polymers 2016 ;Volum 146. s. 197-207
Samuelsen, Anne Berit C.; Rise, Frode; Wilkins, Alistair L.; Teveleva, Lioubov; Nyman, Anna Armika Tussilago; Aachmann, Finn Lillelund. The edible mushroom Albatrellus ovinus contains a α-L-fuco-α-D-galactan, α-D-glucan, a branched (1→6)-β-D-glucan and a branched (1→3)-β-D-glucan. Carbohydrate Research 2019 ;Volum 471. s. 28-38
Nytoft, H. P.; Vukovic, N. S.; Kildahl-Andersen, G.; Rise, F.; Zivotic, D. R.; Stojanovic, K. A.; Identification of a novel series of benzohopanes and its geochemical significance, Energy & Fuels, 2016, 30, 5563-5575.
Nytoft, H. P.; Kildahl-Andersen, G.; Rise, F.; Unusual hexacyclic oleananes in Late Cretaceous/Tertiary terrigenous oils: NMR characterisation of the major hexacyclic oleanane in Niger Delta oil, Org. Geochem., 2016, 101, 196-206.
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Goodman CD, Hoang A, Diallo D, Malterud KE, McFadden GI, Wangensteen H. Anti-plasmodial effects of Zanthoxylum zanthoxyloides. Planta Medica, 2019; 85:1073-1079
Seethapathy GS, Tadesse M, Urumarudappa SKJ, Gunaga S, Vasudeva R, Malterud KE, Shaanker RU, de Boer HJ, Ravikanth G, Wangensteen H. Authentication of Garcinia fruits and food supplements using DNA barcoding and NMR spectroscopy. Scientific Reports 2018; 8:10561
Areta J, Austarheim I, Wangensteen H, Capelli C. Metabolic and performance effects of Yerba Mate on well-trained cyclists. Medicine & Science in Sports & Exercise. 2018; 50:817-826
Ho GTT, Nguyen TKY, Kase ET, Tadesse M, Barsett H, Wangensteen H. Enhanced glucose uptake in human liver cells and inhibition of carbohydrate hydrolyzing enzymes by Nordic berry extracts. Molecules. 2017; 22:1806
Ho GTT, Kase ET, Wangensteen H, Barsett H. Phenolic elderberry extracts, anthocyanins, procyanidins, and metabolites influence glucose and fatty acid uptake in human skeletal muscle cells. Journal of Agricultural and Food Chemistry. 2017; 65:2677-2685
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Nguyen TL, Rusten A, Bugge MS, Malterud KE, Diallo D, Paulsen BS, Wangensteen H. Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers. Journal of Ethnopharmacology. 2016; 192:450-458
Goodman CD, Austarheim I, Mollard V, Mikolo B, Malterud KE, McFadden GI, Wangensteen H. Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite. Malaria Journal, 2016; 15: 481
Wangensteen H, Ho GTT, Tadesse M, Miles CO, Moussavi N, Mikolo B, Malterud KE. A new benzophenanthridine alkaloid and other bioactive constituents from the stem bark of Zanthoxylum heitzii. Fitoterapia. 2016; 109: 196-200
Moussavi N, Malterud KE, Mikolo B, Dawes D, Chandre F, Corbel V, Massamba D, Overgaard H, Wangensteen H. Identification of chemical constituents of Zanthoxylum heitzii stem bark and their insecticidal activity against the malaria mosquito Anopheles gambiae. Parasites & Vectors. 2015; 8: 503
Solum, E.J, Hansen, T. V., Aesoy, R., Herfindal, L. “New CDK8 inhibitors as potential anti-leukemic agents – design, synthesis and biological evaluation.” Eur. J. Med. Chem., 2020, submitted.
Nolsøe, J. M. J., Underhaug, J., Aursnes, M., Stenstrøm, Y. H., Hansen, T. V. ”A Hyperconjugative Model Applied to Structural Assignment of Alicyclic Natural Products,” J. Org. Chem. 2020, 85, manuscript.
Sønderskov, J.,Tungen,J. E., Palmas, F., Dalli, J., Serhan, C. N., Stenstrøm, Y., Hansen, T. V. Tetrahedron Lett., 2020, 61, https://doi.org/10.1016/j.tetlet.2019.151510.
Kristianslund, R., Hansen, T. V.”Enantioselective Bromolactonization of Aryl Functionalized Alkenoic Acids.” Tetrahedron Lett., 2020, 61, in revision.
Nesman, J. I., Tungen, J. E., Vik, A., Hansen, T. V. “Stereoselective Synthesis of the Specialized Pro-resolving and Anti-inflammatory Mediator Resolvin E1“, Tetrahedron, 2020, 76, 130821.
Nolsøe, J. M. J., Aursnes, M., Stenstrøm, Y. H., Hansen, T. V. “Some Biogenetic Considerations Regarding The Marine Natural Product (-)-Mucosin.“ Molecules 2019, 24, 4147.
Vik, A, Kuda, O., Hansen, T. V. “Synthesis of both enantiomers of the docosahexaenoic ester of 13-hydroxyoctadecadienoic acid (13-DHAHLA)“ Tet. Lett., 2019, 60, 15331.
Nesman, J. I., Primdahl, K. G., Tungen, J. E., Palmas, F., Dalli, J., Hansen, T. V. “Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA“, Molecules 2019, 24, 3328.
Fosshaug, L. E., Colas, R. A, Anstensrud, A. K., Gregersen, I., Nymo, S., Michelsen, A., Vinge, L. E., Øie, E., Gullestad, L., Halvorsen, B., Hansen, T. V., Aukrust, P., Dalli, J., Yndestad, A. ”Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction. ” EBioMedicine. 2019, 46, 264.
Tungen, J. E., Kristianslund, R., Vik A., Hansen, T. V. “Organoselenium Accelerated Bromolactonization Reaction.” J. Org. Chem. 2019, 84, 11373.
Arnesen, H., Alazraq, N., Tungen, J. E., Södling, H., Matthews, J., Paulsen, S. M., Nebb, N., Sylte, I., Hansen, T. V., Sæther, T. ”Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPAR-selective agonist”. Bioorg. Med. Chem. 2019, 29, 4059.
Tungen, J. E.; Gerstmann, L.; Vik, A.; De Mateis, R.; Colas, R. A.; Dalli, J.; Chiang, N.; Serhan, C. N.; Kalesse, M.; Hansen, T. V. “Resolving inflammation - Synthesis, Configurational Assignment and Biological Evaluations of RvD1n-3 DPA.” Chem. Eur. J. 2019, 25, 1476.
Johansson, S.R.; Johannessen, T.; Ellefsen, C. F.; Ristun, M. S.; Antonsen, S.; Hansen, T. V.; Stenstrøm, Y.; Nolsøe, J. M. J. “A Convenient Protocol for the Synthesis of Fatty Acid Amides.” SynLett, 2019, 30, 213.
Frigerio, F.; Pasqualini, G.; Craparotta, I.; Marchini, S.; van Vliet, E. A.; Foerch, P.; Vandenplas, C.; Leclercq, K.; Aronica, E.; Porcu, L.; Pistorius, K.; Colas, R. A.; Hansen, T. V.; Perretti, M.; Kaminski, R. M.; Dalli, J.; Vezzani, A. “n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis.” Brain, 2018, 141, 3130.
Nolsøe, J. M. J.; Antonsen, S.; Görbitz, C. H.; Hansen, T. V.; Nesman, J. I.; Røhr, Å. K.; Stenstrøm, Y. H. ”First Total Synthesis of (–)-Mucosin and Revision of Structure” J. Org. Chem. 2018, 86, 15066.
92. Kristianslund, R.; Vik A.; Hansen, T. V. “A convenient synthesis of phenols”. Synth. Commun., 2018, 48, 2809.
91. Tungen, J. E., Aursnes, M., Ramon, S., Colas, R. A., Serhan, C. N., Olberg, D. E., Nuruddin, S., Willoch, F., Hansen, T.V. “Synthesis of Protectin D1 Analogs: Novel Pro-resolution and Radiotracer Agents”. Org. Biomol. Chem. 2018, 16, 6818.
Sæther, T., Paulsen, S. M., Tungen, J. E., Vik, A., Aursnes, M., Holen, T., Hansen, T. V., Nebb, H. I. “Synthesis and Biological Evaluations of Marine Oxohexadecenoic Acids: PPARα/γ Dual Agonism and Anti-Diabetic Target Gene Effects.” Eur. J. Med. Chem., 2018, 155, 736.
Selent, J., Stepniewski, T. M., Fontanals, M., Rodríguez-Espigares, I., Giorgino, T. Primdahl, K. G., Vik, A., Stenstrøm, Y., Hansen T. V. “Synthesis, molecular modelling studies and biological evaluation of new oxoeoicosanoid receptor 1 agonists”. Bioorg. Med. Chem. 2018, 26, 3580.
Pistorius, K. D. F., Souza, P. R., Primdahl, K. G., Colas, R. A., Vik, A., Hansen, T. V., Dalli, J. “PDn-3 DPA pathway regulates human monocyte differentiation and macrophage function”. Cell Chem. Biol., 2018, 25, 749.
Al-Kazaale, N., Tran, P. T., Haidari, F., Solum, E. J., Liekens, S., Vervaeke, P., Sylte, I., Cheng, J.-J., Vik, A., Hansen, T. V. “Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol”. Steroids 2018, 136, 47.
Ricci, F.; Carrassa, L.; Christodoulou, M. S.; Passarella, Danielle; Michel, B; Benhida, R.; Martinet, Nadine; Hunyadi, A.; Ioannou, E.; Roussis, V.; Musso, L.; Dallavalle, S.; Silvestri, R.; Westwood, N.; Mori, Mattia; Ingallina, C.; Botta, Bruno; Kavetsou, E.; Detsi, A.; Majer, Z.; Hudecz, F.; Bősze, S.; Kaminska, B.; Hansen, T. V.; Bertrand, P.; Athanassopoulos, C. M. & Damia, G. “A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells.” Comb. Chem. & High Throughput Screening. 2018, 21, 50.
Kristianslund, R.; Aursnes, M.; Tungen, J. E.; Hansen, T. V. “Synthesis, Biological Investigation, and Structural Revision of Sielboldianin A” J. Nat. Prod. 2018, 81, 1007.
Sørvik, I. B., Solum, E. J., Labba, N. A., Hansen, T.V., Paulsen, R. Free Rad. Res. 2018, 52, 273.
Gregersen, I. S., Askevold, Ø., Tandberg, E., Sagen, E. L., Yang, K., Holm, S.; Pedersen, T. M., Skjelland, M., Krohg-Sørensen, K. Hansen, T. V., Dahl, T. B., Otterdal, K. Espevik, T. Aukrust, P., Yndestad, A., Halvorsen, B. Bente. “Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation” PLoS ONE. 2017, ISSN 1932-6203. 12(11).
Primdahl, K. G., Tungen, J. E., De Souza, P. R. S., Colas, R. A., Dalli, J., Hansen, T. V., Vik A. “Stereocontrolled Synthesis and Investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA.“ Org. Biomol. Chem. 2017, 15, 8606-8613.
Antonsen, S.G., Gallantree-Smith, H.C, Görbitz, C. H., Hansen, T. V., Stenstrøm, Y. H., Nolsøe, J. M. J. “Stereopermutation on the Putative Structure of the Marine Natural Product Mucosin.” Molecules 2017, 22, 1720.
Kaupang, Å., Laitinen,T., Poso, A., Hansen, T. V. “Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of x-ray crystallographic.” Proteins, 2017, 85, 1684.
Gansbeke, K. V., Solum, E. J., Liekens, S., Vik, A., Hansen, T. V. “Regioselective monoalkylation of 17-estradiol for the synthesis of cytotoxic estrogens.” Steroids 2017, 124, 54.
Gobbetti, T., Dalli, J., Colas, R. A., Canova, D. F., Aursnes, M., Bonnet, D., Alric, L., Vergnolle, N., Deraison, C., Hansen, T. V., Serhan, C. N., Perretti, P. “Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection.” Proc. Natl. Acad. Sci. USA. 2017, 114, 3963.
Tian, Y., Aursnes, M., Hansen, T. V., Tungen, J. E., Galpin, J. D., Leisle, L., Ahern, C. A., Xu, R., Heinemann, S. H., Hoshi, T. “Atomic determinants of BK channel activation by polyunsaturated fatty acids.” Proc. Natl. Acad. Sci. USA. 2016, 113, 13905.
Kristianslund, R.; Aursnes, M.; Tungen, J. E.; Hansen, T. V. “Squaramide catalyzed enantioselective iodolactonization of allenoic acids.” Tet. Lett. 2016, 57, 5232.
Primdahl, K. G., Aursnes, M., Walker, M. E., Colas, R. A., Serhan, C. N., Dalli, J., Hansen, T. V., Vik A. “Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins.” J. Nat. Prod. 2016, 79, 2693.
Aursnes, A., Tungen, J. E., Hansen, T.V. “Enantioselective Organocatalyzed Bromolactonizations: Applications in Natural Product Synthesis.“ J. Org. Chem. 2016, 81, 8287.
Filippova, L., Antonsen, S., Stenstrøm, Y., Hansen, T. V. “Synthesis of Obscuraminol A using an organocatalyzed enantioselective Henry reaction.” Tetrahedron, 2016, 72, 6572.
Gallantree-Smith, H.C, Antonsen, S.G., Görbitz, C. H., Hansen, T. V., Nolsøe, J. M. J., Stenstrøm, Y. H. “Total synthesis based on the originally claimed structure of mucosin” Org. Biomol. Chem. 2016, 14, 8433.
Hansen, T. V., Dalli, J., Serhan, C. N. “Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double dioxygenation Isomers.” RSC Advances, 2016, 6, 28820.
Ramon, S., Dalli, J., Sanger, J. M., Winkler, J. W., Aursnes, M., Tungen, J. E., Hansen, T. V., Serhan, C. N. “The Protectin PCTR1 enhances resolution of infectious inflammation and is produced by human M2 macrophages”. Amer. J. Phys., 2016, 186, 962.
Primdahl, K. G., Stenstrøm, Y., Hansen, T. V., Vik, A. “Synthesis of 5-(S)-HETE, 5-(S)-HEPE and (+)-zooxanthellactone: three hydroxylated polyunsaturated fatty acid metabolites.” Chem. Phys. Lipids, 2016, 196, 1.
Kaupang, Å., Kase, E. T., Vo, C. X. T., Amundsen, M., Vik, A., Hansen, T. V. “Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPAR/ antagonists: Effects on the affinity and selectivity towards PPAR/.” Bioorg. Med. Chem. 2016, 24, 247.
Kaupang, Å., Hildonen, S., Halvorsen, T. G., Mortén, M., Vik, A., Hansen, T. V. “Involvement of Covalent Interactions in the Mode of Action of PPARβ/δ Antagonists.” RSC Advances, 2015, 5, 76483.
Tungen, J. E., Aursnes, A., Vlasakov, I., Colas, R. A., Dalli, J., Serhan, C. N., Hansen, T. V. “Synthesis of the 16S,17S-epoxy-Protectin Intermediate in the Biosynthesis of Protectins by Human Macrophages.” J. Nat. Prod. 2015, 78, 2924.
Primdahl, K. G, Aursnes, M., Tungen, J. E., Hansen, T. V.,Vik, A. “An efficient synthesis of leukotriene B4” Org. Biomol. Chemistry 2015, 13, 5412.
Solum E. J., Cheng, Sylte, I., Vik, A., Hansen, T. V. “Synthesis, biological evaluations and molecular modeling of new analogs of the anti-cancer agent 2-methoxyestradiol: Potent inhibitors of angiogenesis.” RSC Advances, 2015, 5, 32497.
Filippova, L., Hansen, T. V., Stenstrøm, Y. “Cu (II)-catalyzed asymmetric Henry reaction with a novel C1-symmetric aminopinane-derived ligand”Molecules 2015, 20, 6224.
Filippova, L., Aarum, I., Ringdal, M., Dahl, M. K., Hansen, T. V., Stenstrøm, Y. “Synthesis of (all-Z)-hentriaconta-3,6,9,12,15,19,22,25,28-nonaene. “Org. Biomol. Chemistry 2015, 13, 4680.
Kaupang, A., Paulsen, S. M., Steindal, C. C., Ravna, A. W., Sylte, I., Halvorsen, T. G., Thoresen, G. H., Hansen, T. V. “Synthesis, biological evaluation and molecular modeling studies of the PPAR δ antagonist CC618”. Eur. J. Med. Chem., 2015, 94, 229.
Tungen, J. E., Aursnes, M., Hansen, T. V. “Stereoselective Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator Maresin 1. “Tetrahedron Lett., 2015, 56, 1843.
Nolsøe, J. M., Aursnes, M., Tungen, J. E., Hansen, T. V. “Dienals derived from pyridinium salts and their subsequent application in natural product synthesis”. J. Org. Chem., 2015, 80, 5377-5385.
Solum, E. J., Akselsen, Ø. W., Vik, A., Hansen, T. V. “Synthesis and pharmacological effects of the anti-cancer agent 2-methoxyestradiol”, Curr. Pharm. Design., 2015, 21, 5453-5466.
Vik, A., Dalli, J., Hansen, T. V. ”Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid”. Bioorg. Med. Chem. Lett., 2017, 27, 2259.
Hansen, T. V., Dalli, J., Serhan, C. N. “The Novel Lipid Mediator PD1n-3 DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions.” Prostaglandins Other Lipid Mediat. 2017, 133, 103-110.
Vik, A., Hansen, T. V. “Synthetic manipulations of polyunsaturated fatty acids as a convenient strategy for the synthesis of bioactive compounds.” Org. Biomol. Chem. 2018, 16, 9319-9333.
Hansen, T. V., Vik, A., Serhan, C. N. “The Protectin Family of Specialized Pro-Resolving Mediators: Potent Immunoresolvents Enabling Innovative Approaches to Target Obesity and Diabetes.” Frontiers in Pharmacology. 2019, doi:10.3389/fphar.2018.01582.
Kristianslund, R., Tungen, J. E., Hansen, T. V. “Enantioselective Iodolactonizations”. Org. Biomol. Chem., 2019, 19, 3079.
Vik, A., Hansen, T. V. “Fatty Acids and their Derivatives.” In From Biosynthesis to Total Synthesis. Ed.: A. L. Zografos, Wiley, Wiley ISBN 978-1-118-75173-2, 2016, 130 – 161.
Hansen, T. V., Skattebøl, L. “Ortho-Formylations of Phenols. Preparation of 3-bromo salicylaldehyde. Chapter 132”. In Comprehensive Organic Chemistry Experiments for the Laboratory, Royal Society of Chemistry, Ed.: Afonso, C. A. M., Candeias, N. R., Simão, D. P., Trindade, A. F., Coelho, J. A. S., Tan, B., Franzén, R. 2016, ISBN 978-1-84973-963-4.
G. Isapour, R. Lund, K. Zhu, Z. Quan, K. D. Knudsen , and B. Nyström Schizophrenic Micellization in Aqueous Solutions of the pH- and Temperature Responsive Pentablock Terpolymer PDEAEMAx-b-PNIPAAMy-b-PEGz-b-PNIPAAMy-b-PDEAEMA European Polymer Journal 70, 79 (2015).(DRX 500)
J. Lyngsø, N. Al Manasir, M. A. Behrens, K. Zhu, A.-L. Kjøniksen, B. Nyström, and J. Skov Pedersen Small-angle X-ray Scattering Studies of Thermo-Responsive poly(N-isopropylacrylamide) Star Polymers in Water. Macromolecules 48, 2235 (2015). (DPX 300)
S. Bekhradnia, J. Stensgaard Diget, T. Zinn, K. Zhu, S. A. Sande, B. Nyström, and R. Lund Charged Diblock Copolymer Stars in Dilute Solutions: Synthesis, Structure, and Chain Conformations Macromolecules 48, 2637 (2015). (AVI 600)
R. Pamies, K. Zhu, A.-L. Kjøniksen, and B. Nyström Temperature Effects on the Stability of Gold Nanoparticles in the Presence of a Cationic Thermoresponsive Copolymer Journal of Nanoparticle Research 18 (11), 1-12 (2016). (DPX 300)
F. Kahnamouei, K. Zhu,, R. Lund, K. D. Knudsen, and B. Nyström Self-assembly of a Hydrophobically End-capped Charged Amphiphilic Triblock Copolymer: Effects of Temperature and Salinity RSC Advances 5, 46916 (2015). (DPX 300)
B. Claro, K. Zhu, S. Bagherifam , S. G. Silva, G. Griffiths, K. D. Knudsen, E. F. Marques, and B. Nyström Phase Behavior, Microstructure and Cytotoxicity in Mixtures of a Charged Triblock Copolymer and an Ionic Surfactant European Polymer Journal 75, 461 (2016). (AVI 600)
N. Khameh Khorshid, K. Zhu, K. D. Knudsen, S. Bekhradnia, S. A. Sande, and B. Nyström Novel Structural Changes during Temperature-Induced Self-assembling and Gelation of PLGA-PEG-PLGA Triblock Copolymer in Aqueous Solutions Macromolecular Bioscience 16, 1838-1852 (2016). (DPX 300)
J. Eilsø Nielsen, K. Zhu, S. A. Sande, L. Kováčik, D. Cmarko, K. D. Knudsen, and B. Nyström Structural and Rheological Properties of Temperature-Responsive Amphiphilic Triblock Copolymers in Aqueous Media Journal Physical Chemistry B 121, 4885−4899 (2017). (AVII 400)
N. Gjerde, K. Zhu, B. Nyström, and K. D. Knudsen Effect of PCL end-groups on the self-assembling process of Pluronic in aqueous media Phys. Chem. Chem. Phys. 20, 2585-2596 (2018). (DPX 300)
Nesman, J. I.; Tungen, J. E.; Vik, A.; Hansen, T. V., Stereoselective synthesis of the specialized pro-resolving and anti-inflammatory mediator resolvin E1. Tetrahedron. 2020, 76, 130821.
Vik, A.; Hansen, T. V.; Kuda, O., Synthesis of both enantiomers of the docosahexaenoic acid ester of 13-hydroxyoctadecadienoic acid (13-DHAHLA). Tetrahedron Lett. 2019, 60 (52), 151331.
Tungen, J. E.; Kristianslund, R.; Vik, A.; Hansen, T. V., Organoselenium Accelerated Bromolactonization Reaction. J. Org. Chem. 2019, 84 (18), 11373-11381
Tungen, J. E.; Gerstmann, L.; Vik, A.; De Matteis, R.; Colas, R. A.; Dalli, J.; Chiang, N.; Serhan, C. N.; Kalesse, M.; Hansen, T. V., Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. Chemistry 2019, 25 (6), 1476-1480.
al-Kazaale, N.; Tran, P. T.; Haidari, F.; Solum, E. J.; Liekens, S.; Vervaeke, P.; Sylte, I.; Cheng, J.-J.; Vik, A.; Hansen, T. V., Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol. Steroids 2018, 136, 47-55.
Stepniewski, T. M.; Torrens-Fontanals, M.; Rodriguez-Espigares, I.; Giorgino, T.; Primdahl, K. G.; Vik, A.; Stenstroem, Y.; Selent, J.; Hansen, T. V., Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorg. Med. Chem. 2018, 26 (12), 3580-3587.
Saether, T.; Paulsen, S. M.; Tungen, J. E.; Vik, A.; Aursnes, M.; Holen, T.; Hansen, T. V.; Nebb, H. I., Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects. Eur. J. Med. Chem. 2018, 155, 736-753.
Pistorius, K.; Souza, P. R.; De Matteis, R.; Austin-Williams, S.; Primdahl, K. G.; Vik, A.; Mazzacuva, F.; Colas, R. A.; Marques, R. M.; Hansen, T. V.; Dalli, J., PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function. Cell Chem Biol 2018, 25 (6), 749-760.e9.
Kristianslund, R.; Vik, A.; Hansen, T. V., A convenient synthesis of phenols. Synthetic Communications 2018, 48 (21), 2809-2814.
Primdahl, K. G.; Tungen, J. E.; De Souza, P. R. S.; Colas, R. A.; Dalli, J.; Hansen, T. V.; Vik, A., Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA. Org. Biomol. Chem. 2017, 15, 8606- 8613.
Gansbeke, K. V.; Solum, E. J.; Liekens, S.; Vik, A.; Hansen, T. V., Regioselective monoalkylation of 17β-estradiol for the synthesis of cytotoxic estrogens. Steroids 2017, 124, 54-59.
Kaupang, A.; Kase, E. T.; Vo, C. X. T.; Amundsen, M.; Vik, A.; Hansen, T. V., Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ. Bioorg. Med. Chem. 2016, 24 (2), 247-260.
Primdahl, K. G.; Aursnes, M.; Walker, M. E.; Colas, R. A.; Serhan, C. N.; Dalli, J.; Hansen, T. V.; Vik, A., Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. J. Nat. Prod. 2016, 79 (10), 2693-2702.
Primdahl, K. G.; Stenstroem, Y.; Hansen, T. V.; Vik, A., Synthesis of 5-(S)-HETE, 5-(S)-HEPE and (+)-zooxanthellactone: Three hydroxylated polyunsaturated fatty acid metabolites. Chem. Phys. Lipids 2016, 196, 1-4.
Tungen, J. E.; Aursnes, M.; Vik, A., Synthesis of Ieodomycin D. Synlett 2016, 27 (17), 2497-2499.
Kaupang, A.; Hildonen, S.; Halvorsen, T. G.; Morten, M.; Vik, A.; Hansen, T. V., Involvement of covalent interactions in the mode of action of PPARβ/δ antagonists. RSC Adv. 2015, 5 (93), 76483-76490.
Primdahl, K. G.; Tungen, J. E.; Aursnes, M.; Hansen, T. V.; Vik, A., An efficient total synthesis of leukotriene B4. Org. Biomol. Chem. 2015, 13 (19), 5412-5417.
Solum, E. J.; Akselsen, O. W.; Vik, A.; Hansen, T. V., Synthesis and Pharmacological Effects of the Anti-Cancer Agent 2-Methoxyestradiol. Curr. Pharm. Des. 2015, 21 (38), 5453-5466.
Solum, E. J.; Cheng, J.-J.; Sylte, I.; Vik, A.; Hansen, T. V., Synthesis, biological evaluation and molecular modeling of new analogs of the anti-cancer agent 2-methoxyestradiol: potent inhibitors of angiogenesis. RSC Adv. 2015, 5 (41), 32497-32504.
Peeters, Sara; Berntsen, Linn Neerbye; Rongved, Pal; Bonge-Hansen, Tore Beilstein Journal of Organic Chemistry (2019), 15, 2156-2160.
Levchenko, Vladimir; Sundsli, Bard; Oien-Odegaard, Sigurd; Tilset, Mats; Hansen, Finn K.; Bonge-Hansen, Tore European Journal of Organic Chemistry (2018), 2018(44), 6150-6157.
Viktorsson, Elvar Orn; Melling Groethe, Bendik; Aesoy, Reidun; Sabir, Misbah; Snellingen, Simen; Prandina, Anthony; Hoegmoen Aastrand, Ove Alexander; Bonge-Hansen, Tore; Doeskeland, Stein Ove; Herfindal, Lars; et al Bioorganic & Medicinal Chemistry (2017), 25(7), 2285-2293.
Morten, Magnus; Hennum, Martin; Bonge-Hansen, Tore Beilstein Journal of Organic Chemistry (2016), 12, 1590-1597.
Morten, Magnus; Hennum, Martin; Bonge-Hansen, Tore Beilstein Journal of Organic Chemistry (2015), 11, 1944-1949.
Yadav, Vitthal N.; Comotti, Angiolina; Sozzani, Piero; Bracco, Silvia; Bonge-Hansen, Tore; Hennum, Martin; Goerbitz, Carl Henrik Angewandte Chemie, International Edition (2015), 54(52), 15684-15688.
N. Moussavi, K.E. Malterud, B. Mikolo, D. Dawes, F. Chandre, V. Corbel, D. Massamba, H.J. Overgaard, H. Wangensteen: Identification of chemical constituents of Zanthoxylum heitzii stem bark and their insecticidal activity against the malaria mosquito Anopheles gambiae. Parasites & Vectors 8(2015), 503 (8pp).
H. Wangensteen, G.T.T. Ho, M. Tadesse, C.O. Miles, N. Moussavi, B. Mikolo, K.E. Malterud: A new benzophenanthridine alkaloid and other bioactive constituents from the stem bark of Zanthoxylum heitzii. Fitoterapia 109 (2016), 196-200.
C.D. Goodman, I. Austarheim, V. Mollard, B. Mikolo, K.E. Malterud, G.I. McFadden, H. Wangensteen: Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite. Malaria Journal 15 (2016), 481. (Erratum: Malaria Journal 15 (2016), 560).
T.L. Nguyen, A. Rusten, M.S. Bugge, K.E. Malterud, D. Diallo, B.S. Paulsen, H. Wangensteen: Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers. Journal of Ethnopharmacology 192 (2016), 450-458.
G.S. Seethapathy, M. Tadesse, J.U.S. Kumar, S. Gunaga, R. Vasudeva, K.E. Malterud, R.U.S. Shaanker, H.J. de Boer, G. Ravikanth, H. Wangensteen: Authentication of Garcinia fruits and food supplements using DNA barcoding and NMR raises quality concerns for food supplements. Scientific Reports 8 (2018), 10561 (12 sider + supplement, 45 sider)
C.D. Goodman, Q.T. Hoang, D. Diallo, K.E. Malterud, G.I. McFadden, H. Wangensteen: Anti-plasmodial effects of Zanthoxylum zanthoxyloides. Planta Medica 85 (2019), 1073-1079 + supplement, 22 sider.
F. Lawal, M.J. Bapela, S.A. Adebayo, S.M. Nkadimeng, K.E. Malterud, L.J. McGaw, T.E. Tshikalange: Anti-inflammatory potential of South African medicinal plants used in the treatment of sexually transmitted infections. South African Journal of Botany 125 (2019), 62-71.
I. C. Hvinden, H. Engen Berg, D. Sachse, E. Skaga, F. S. Skottvoll, E. Lundanes, C. J. Sandberg, E. O. Vik-Mo, F. Rise & S. R. Wilson, "Nuclear magnetic resonance spectroscopy to identify metabolite biomarkers of non-responsiveness to targeted therapy in glioblastoma tumor stem cells", Journal of Proteome Research 18, 2012-2020 (2019) doi:10.1021/acs.jproteome.8b00801
D.-J. Pang, C. Huang, M.-L. Chen, Y.-L. Chen, Y.-P. Fu, B. S. Paulsen, F. Rise, B.-Z. Zhang, Z.-L. Chen, R.-Y. Jia, L.-X. Li, X. Song, B. Feng, X.-Q. Ni, Z.-Q. Yin & Y.-F. Zou, "Characterization of inulin-type fructan from Platycodon grandiflorus and study on its prebiotic and immunomodulating activity", Molecules 24, (2019) doi:10.3390/molecules24071199
J. S. Murray, A. I. Selwood, D. T. Harwood, R. van Ginkel, J. Puddick, L. L. Rhodes, F. Rise & A. L. Wilkins, "44-methylgambierone, a new gambierone analogue isolated from Gambierdiscus australes",Tetrahedron Letters , (2019) doi:10.1016/j.tetlet.2019.01.043
A. B. C. Samuelsen, F. Rise, A. L. Wilkins, L. Teveleva, A. A. T. Nyman & F. L. Aachmann, "The edible mushroom Albatrellus ovinus contains a α-l-fuco-α-d-galactan, α-d-glucan, a branched (1 → 6)-β-d-glucan and a branched (1 → 3)-β-d-glucan", Carbohydr. Res. 471, 28-38 (2019) doi:10.1016/j.carres.2018.10.012
A. J. Foss, C. O. Miles, I. A. Samdal, K. E. Løvberg, A. L. Wilkins, F. Rise, J. A. H. Jaabæk, P. C. McGowan & M. T. Aubel, "Analysis of free and metabolized microcystins in samples following a bird mortality event", Harmful Algae 80, 117-129 (2018)
doi:10.1016/j.hal.2018.10.006 J. Wåhlander, M. Amedjkouh & L.-L. Gundersen,
"Synthesis directed towards trans-clerodanes employing an exo-selective Diels-Alder reaction as a key-step", Monatsh. Chem. , 1-10 (2018) doi:10.1007/s00706-018-2277-9
M. S. M. Holmsen, A. Nova, K. Hylland, D. S. Wragg, S. Øien-Ødegaard, R. H. Heyn & M. Tilset, "Synthesis of a (N, C, C) Au (III) pincer complex via C sp3-H bond activation: increasing catalyst robustness by rational catalyst design", Chemical Communications 54, 11104-11107 (2018) doi:10.1039/c8cc05489d
M. S. M. Holmsen, F. S. Ihlefeldt, S. Øien-Ødegaard, E. Langseth, Y. Wencke, R. H. Heyn & M. Tilset, "Markovnikov at gold: nucleophilic addition to alkenes at Au (III)", Organometallics 37, 1937-1947 (2018) doi:10.1021/acs.organomet.8b00218 J. E. Jakobsson & P. J. Riss, "Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex", RSC Advances 8, 21288-21291 (2018) doi:10.1039/c8ra03757d C. W. Wold, C. Kjeldsen, A. Corthay, F. Rise, B. E. Christensen, J. Ø. Duus & K. T. Inngjerdingen, "Structural characterization of bioactive heteropolysaccharides from the medicinal fungus Inonotus obliquus (Chaga)", Carbohydrate Polymers 185, 27-40 (2018) doi:10.1016/j.carbpol.2017.12.041
N. T. Kenton, D. Adu-Ampratwum, A. A. Okumu, Z. Zhang, Y. Chen, S. Nguyen, J. Xu, Y. Ding, P. McCarron, J. Kilcoyne, F. Rise, A. L. Wilkins, C. O. Miles & C. J. Forsyth, "Total Synthesis of (6R,10R,13R,14R,16R,17R,19S,20R,21R,24S, 25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 Reveals Non-Identity with the Natural Product", Angewandte Chemie International Edition 57, 805-809 (2017) doi:10.1002/anie.201711006
N. T. Kenton, D. Adu-Ampratwum, A. A. Okumu, P. McCarron, J. Kilcoyne, F. Rise, A. L. Wilkins, C. O. Miles & C. J. Forsyth, "Stereochemical Definition of the Natural Product (6R ,10R ,13R , 14R ,16R ,17R ,19S ,20S ,21R ,24S ,25S ,28S ,30S ,32R ,33R ,34R ,36S ,37S ,39R )-Azaspiracid-3 by Total Synthesis and Comparative Analyses", Angewandte Chemie International Edition 57, 810-813 (2017) doi:10.1002/anie.201711008
S. Furse, M. Jakubec, F. Rise, H. E. Williams, C. E. Rees & Ø. Halskau, "Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle", Scientific Reports 7, 8012 (2017) doi:10.1038/s41598-017-06855-z
Y. N. Georgiev, B. S. Paulsen, H. Kiyohara, M. Ciz, M. H. Ognyanov, O. Vasicek, F. Rise, P. N. Denev, A. Lojek, T. G. Batsalova, B. M. Dzhambazov, H. Yamada, R. Lund, H. Barsett, A. I. Krastanov, I. Z. Yanakieva & M. G. Kratchanova, "Tilia tomentosa pectins exhibit dual mode of action on phagocytes as Β-glucuronic acid monomers are abundant in their rhamnogalacturonans I", Carbohydrate Polymers 175, 178-191 (2017) doi:10.1016/j.carbpol.2017.07.073
Y. N. Georgiev, B. S. Paulsen, H. Kiyohara, M. Ciz, M. H. Ognyanov, O. Vasicek, F. Rise, P. N. Denev, H. Yamada, A. Lojek, V. Kussovski, H. Barsett, A. I. Krastanov, I. Z. Yanakieva & M. G. Kratchanova, "The common lavender (Lavandula angustifolia Mill.) pectic polysaccharides modulate phagocytic leukocytes and intestinal Peyer’s patch cells", Carbohydrate Polymers 174, 948-959 (2017) doi:10.1016/j.carbpol.2017.07.011
H. P. Nytoft, G. Kildahl-Andersen & F. Rise, "Unusual hexacyclic oleananes in Late Cretaceous/Tertiary terrigenous oils: NMR characterisation of the major hexacyclic oleanane in Niger Delta oil", Org. Geochem. 101, 196-206 (2016) doi:10.1016/j.orggeochem.2016.08.016
A. Stanic, S. Uhlig, M. Sandvik, F. Rise, A. L. Wilkins & C. O. Miles, "Characterization of Deoxynivalenol-Glutathione Conjugates Using Nuclear Magnetic Resonance Spectroscopy and Liquid Chromatography-High-Resolution Mass Spectrometry.", J. Agric. Food Chem. 64, 6903-6910 (2016) doi:10.1021/acs.jafc.6b02853
D.-J. Pang, C. Huang, M.-L. Chen, Y.-L. Chen, Y.-P. Fu, B. S. Paulsen, F. Rise, B.-Z. Zhang, Z.-L. Chen, R.-Y. Jia, L.-X. Li, X. Song, B. Feng, X.-Q. Ni, Z.-Q. Yin & Y.-F. Zou, "Characterization of inulin-type fructan from Platycodon grandiflorus and study on its prebiotic and immunomodulating activity", Molecules 24, (2019) doi:10.3390/molecules24071199
J. S. Murray, A. I. Selwood, D. T. Harwood, R. van Ginkel, J. Puddick, L. L. Rhodes, F. Rise & A. L. Wilkins, "44-methylgambierone, a new gambierone analogue isolated from Gambierdiscus australes", Tetrahedron Letters , (2019) doi:10.1016/j.tetlet.2019.01.043
A. B. C. Samuelsen, F. Rise, A. L. Wilkins, L. Teveleva, A. A. T. Nyman & F. L. Aachmann, "The edible mushroom Albatrellus ovinus contains a α-l-fuco-α-d-galactan, α-d-glucan, a branched (1 → 6)-β-d-glucan and a branched (1 → 3)-β-d-glucan", Carbohydr. Res. 471, 28-38 (2019) doi:10.1016/j.carres.2018.10.012
A. J. Foss, C. O. Miles, I. A. Samdal, K. E. Løvberg, A. L. Wilkins, F. Rise, J. A. H. Jaabæk, P. C. McGowan & M. T. Aubel, "Analysis of free and metabolized microcystins in samples following a bird mortality event", Harmful Algae 80, 117-129 (2018) doi:10.1016/j.hal.2018.10.006 J. Wåhlander, M. Amedjkouh & L.-L. Gundersen, "Synthesis directed towards trans-clerodanes employing an exo-selective Diels-Alder reaction as a key-step", Monatsh. Chem. , 1-10 (2018) M. S. M. Holmsen, A. Nova, K. Hylland, D. S. Wragg, S. Øien-Ødegaard, R. H. Heyn & M. Tilset, "Synthesis of a (N, C, C) Au (III) pincer complex via C sp3-H bond activation: increasing catalyst robustness by rational catalyst design", Chemical Communications 54, 11104-11107 (2018) doi:10.1039/c8cc05489d M. S. M. Holmsen, F. S. Ihlefeldt, S. Øien-Ødegaard, E. Langseth, Y. Wencke, R. H. Heyn & M. Tilset, "Markovnikov at gold: nucleophilic addition to alkenes at Au (III)", Organometallics 37, 1937-1947 (2018) doi:10.1021/acs.organomet.8b00218 J. E. Jakobsson & P. J. Riss
"Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex", RSC Advances 8, 21288-21291 (2018) doi:10.1039/c8ra03757d
C. W. Wold, C. Kjeldsen, A. Corthay, F. Rise, B. E. Christensen, J. Ø. Duus & K. T. Inngjerdingen, Structural characterization of bioactive heteropolysaccharides from the medicinal fungus Inonotus obliquus (Chaga)", arbohydrate Polymers 185, 27-40 (2018) oi:10.1016/j.carbpol.2017.12.041
N. T. Kenton, D. Adu-Ampratwum, A. A. Okumu, Z. Zhang, Y. Chen, S. Nguyen, J. Xu, Y. Ding, P. McCarron, J. Kilcoyne, F. Rise, A. L. Wilkins, C. O. Miles & C. J. Forsyth, Total Synthesis of (6R,10R,13R,14R,16R,17R,19S,20R,21R,24S, 25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 Reveals Non-Identity with the Natural Product", ngewandte Chemie International Edition 57, 805-809 (2017) oi:10.1002/anie.201711006
N. T. Kenton, D. Adu-Ampratwum, A. A. Okumu, P. McCarron, J. Kilcoyne, F. Rise, A. L. Wilkins, C. O. Miles & C. J. Forsyth, Stereochemical Definition of the Natural Product (6R ,10R ,13R , 14R ,16R ,17R ,19S ,20S ,21R ,24S ,25S ,28S ,30S ,32R ,33R ,34R ,36S ,37S ,39R )-Azaspiracid-3 by Total Synthesis and Comparative Analyses", ngewandte Chemie International Edition 57, 810-813 (2017) oi:10.1002/anie.201711008
S. Furse, M. Jakubec, F. Rise, H. E. Williams, C. E. Rees & Ø. Halskau, Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle", cientific Reports 7, 8012 (2017) oi:10.1038/s41598-017-06855-z
Y. N. Georgiev, B. S. Paulsen, H. Kiyohara, M. Ciz, M. H. Ognyanov, O. Vasicek, F. Rise, P. N. Denev, A. Lojek, T. G. Batsalova, B. M. Dzhambazov, H. Yamada, R. Lund, H. Barsett, A. I. Krastanov, I. Z. Yanakieva & M. G. Kratchanova, Tilia tomentosa pectins exhibit dual mode of action on phagocytes as Β-glucuronic acid monomers are abundant in their rhamnogalacturonans I" arbohydrate Polymers 175, 178-191 (2017) oi:10.1016/j.carbpol.2017.07.073 .
N. Georgiev, B. S. Paulsen, H. Kiyohara, M. Ciz, M. H. Ognyanov, O. Vasicek, F. Rise, P. N. Denev, H. Yamada, A. Lojek, V. Kussovski, H. Barsett, A. I. Krastanov, I. Z. Yanakieva & M. G. Kratchanova,"The common lavender (Lavandula angustifolia Mill.) pectic polysaccharides modulate phagocytic leukocytes and intestinal Peyer’s patch cells", arbohydrate Polymers 174, 948-959 (2017) oi:10.1016/j.carbpol.2017.07.011
P. Nytoft, G. Kildahl-Andersen & F. Rise, Unusual hexacyclic oleananes in Late Cretaceous/Tertiary terrigenous oils: NMR characterisation of the major hexacyclic oleanane in Niger Delta oil", rg. Geochem. 101, 196-206 (2016) oi:10.1016/j.orggeochem.2016.08.016
A.Stanic, S. Uhlig, M. Sandvik, F. Rise, A. L. Wilkins & C. O. Miles, Characterization of Deoxynivalenol-Glutathione Conjugates Using Nuclear Magnetic Resonance Spectroscopy and Liquid Chromatography-High-Resolution Mass Spectrometry.", . Agric. Food Chem. 64, 6903-6910 (2016) oi:10.1021/acs.jafc.6b02853
H. P. Nytoft, N. Vuković, G. Kildahl-Andersen, F. Rise, D. Životić & K. Stojanovic, Identification of a novel series of benzohopanes and its geochemical significance", Eergy & Fuels 30, 5563-5575 (2016) oi:10.1021/acs.energyfuels.6b00799
C. O. Miles, M. Sandvik, H. E. Nonga, A. Ballot, A. L. Wilkins, F. Rise, J. A. H. Jaabaek & J. I. Loader, "onjugation of microcystins with thiols is reversible: Base-catalyzed deconjugation for chemical analysis", Cemical research in toxicology 29, 860-870 2016)doi:10.1021/acs.chemrestox.6b00028
A. A. T. Nyman, F. L. Aachmann, F. Rise, S. Ballance & A. B. C. Samuelsen,
"Structural characterization of a branched (1→6)-α-mannan and β-glucans isolated from the fruiting bodies of Cantharellus cibarius." Cbohydrate Polymers 146, 197-207 (2016)"Identification of a novel series of benzohopanes and its geochemical significance",Energy & Fuels 30, 5563-5575 (2016) Doi10.1021/acs.energyfuels.6b00799
C. O. Miles, M. Sandvik, H. E. Nonga, A. Ballot, A. L. Wilkins, F. Rise, J. A. H. Jaabaek & J. I. Loader, "Conjugation of microcystins with thiols is reversible: Base-catalyzed deconjugation for chemical analysis", Chemical research in toxicology 29, 860-870 (2016) doi:10.1021/acs.chemrestox.6b00028
A. A. T. Nyman, F. L. Aachmann, F. Rise, S. Ballance & A. B. C. Samuelsen,"Structural characterization of a branched (1→6)-α-mannan and β-glucans isolated from the fruiting bodies of Cantharellus cibarius.",Carbohydrate Polymers 146, 197-207 (2016)