Steven Ray Haakon Wilson
Jeg (og mine supre studenter!) utvikler fremgangsmåter og instrumenter for å måle stoffer i kroppen. Dette gir informasjon som hjelper å forstå sykdommer og lidelser. Min spesialitet er å måle på metabolitter/proteiner/legemidler i små prøver, med raske og automatisert utstyr. Stikkord i denne sammenheng er nano-væskekromatografi (nano-liquid chromatography) og massespektrometri.
Jeg er veldig glad i multidisiplinære prosjekter, og er medlem av forskningsmiljøene DIATECH@UiO and CHIP.
Sjekk meg ut på Twitter and Google Scholar.
Publikasjoner
"A multi-channeled open tubular enzyme reactor on-line coupled with mass spectrometry for detecting ricin". Ole Kristian Brandtzaeg, Bent-Tore Roen, Siri Enger, Elsa Lundanes, Steven Ray Wilson. Anal. Chem. 2017 89 (17), 8667-8673
"Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes". Roberg-Larsen H, Lund K, Seterdal KE, Solheim S, Vehus T, Solberg N, Krauss S, Lundanes E, Wilson SR. J Steroid Biochem Mol Biol. 2017 169, 22-28
"Kisspeptin, A Neuroendocrine Modulator of Sexual and Emotional Processing in Men". Alexander N Comninos, Matthew B Wall, Lysia Demetriou, Amar J Shah, Sophie Clarke, Shakunthala Narayanaswamy, Alexander Nesbitt, Chioma Izzi-Engbeaya, Julia K Prague, Ali Abbara, Risheka Ratnasabapathy, Victoria Salem, Gurjinder M Nijher, Channa N Jayasena, Mark Tanner, Paul Bassett, Amrish Mehta, Eugenii A Rabiner, Christoph Hönigsperger, Meire Ribeiro Silva, Ole Kristian Brandtzaeg, Elsa Lundanes, Steven Ray Wilson, Stephen R Bloom and Waljit S Dhillo. Journal of Clinical Investigation, 2017; 127(2):709–719.
"Proteomics tools reveal startlingly high amounts of oxytocin in plasma and serum". Brandtzaeg OK, Johnsen E, Roberg-Larsen H, Seip KF, MacLean EL, Gesquiere LR, Leknes S, Lundanes E, Wilson SR. Sci Rep. 6, Article number: 31693 (2016).
"Nano-LC in proteomics: recent advances and approaches". SR Wilson, T Vehus, HS Berg, E Lundanes. Bioanalysis 7 (14), 1799-1815
"On-line solid phase extraction-liquid chromatography, with emphasis on modern bioanalysis and miniaturized systems". M Rogeberg, H Malerod, H Roberg-Larsen, C Aass, SR Wilson, Journal of Pharmaceutical and Biomedical Analysis, 2014 Jan; 87:120-9
"Polylactide-co glycolide-rifampicin-nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes". Kalluru R, Fenaroli F, Westmoreland D, Ulanova L, Maleki A, Roos N, Paulsen Madsen M, Koster M, Eggerli Jacobsen W, Wilson SR, Roberg-Larsen H, Khuller GK, Singh A, Nyström B, Griffiths G. Journal of Cell Science, 2013 Jul 15;126:3043-54.
"Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor" Andrey Voronkov, Dan Holsworth, Jo Waaler, Steven Ray Wilson, Bie Ekblad, Harmonie Dahl, Huyen Dinh, Gerard Drewes, Carsten Hopf, Jens Preben Morth, Stefan Krauss. Journal of Medicinal Chemistry, 2013, 56 (7), 3012–3023.
"The novel tankyrase ½ inhibitor JW55 interferes with canonical Wnt signaling in colon carcinoma cell lines in vitro and reduces tumor growth in conditional APC mutant mice in vivo". Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Machonova O, Gradl D, von Kries JP, Krauss S. Cancer Research, 2012 Jun 1;72(11):2822-32.