Dirk Linke

Image of Dirk Linke
Norwegian version of this page
Phone +47 22857654
Room 3517
Username
Visiting address Blindernveien 31 None 0371 OSLO
Postal address Postboks 1066 Blindern 0316 OSLO

Academic Interests

My research group focusses on the structure and function of the bacterial cell surface. Currently, we work on three main topics:

  1. Bacterial Adhesion: How do bacteria stick to surfaces, or in the case of pathogens, to host cells?
  2. Membrane transport: how are adhesion molecules transported to the cell surface? And can this process be inhibited with novel antimicrobial substances?
  3. Vaccines and Biomarkers: can we exploit bacterial surface proteins as vaccine candidates or as biomarkers, e.g. for improved clinical diagnostics?

Our work is typically comparative – we do not work on a single pathogenic “pet” organism, but instead compare related surface proteins from different species, studying their similarities and subtle differences. Our work is also interdisciplinary – we use methods from bioinformatics, structural biology and biophysics on top of classical methods from microbiology, molecular biology and biochemistry.
 

Teaching

  • MBV 3060 (Basic Microbiology)
  • MBV 4910 (iGEM Competition)
  • ...


Higher education and employment history

  • since 2015 Full Professor, Department of Biosciences, UiO
  • since 2013 Associate Professor, Department of Biosciences, UiO
  • 2010 Habilitation, Department of Biology, University of Tübingen
  • 2007-2013 Project Leader, Max Planck Institute for Developmental Biology, Tübingen
  • 2003-2007 PostDoc, Max Planck Institute for Developmental Biology, Tübingen
  • 2002 PhD, Department of Chemistry, TU Berlin
  • 1991-1997, undergraduate studies in Biochemistry, FU Berlin
     

Honoraria

  • 2009 Young Academics Award from the German Society for Hygiene and Microbiology
  • 2008 and 2009 two 1-year stipends from the Bill & Melinda Gates Foundation
  • ...

Appointments

  • Advisory Board Member, Molecular Microbiology (Wiley)
  • Review Editor, Journal of Biological Chemistry
  • Review Editor, Frontiers in Microbiology

Publications

  • Ryoo, David; Rydmark, Marcella Orwick; Pang, Yui Tik; Lundquist, Karl P; Linke, Dirk & Gumbart, James C (2020). BamA is required for autotransporter secretion. Biochimica et Biophysica Acta - General Subjects.  ISSN 0304-4165.  1864(7), s 1- 8 . doi: 10.1016/j.bbagen.2020.129581
  • Aoki, S.; Yoshimoto, Shogo; Ishikawa, M; Linke, Dirk; Lupas, Andrei & Hori, Katsutoshi (2019). Native display of a huge homotrimeric protein fiber on the cell surface after precise domain deletion. Journal of Bioscience and Bioengineering.  ISSN 1389-1723.  s 1- 6 . doi: 10.1016/j.jbiosc.2019.09.022
  • Chauhan, Nandini; Hatlem, Daniel; Rydmark, Marcella Orwick; Schneider, Kenneth; Flötenmeyer, Matthias; Van Rossum, Barth-J; Leo, Jack Christopher & Linke, Dirk (2019). Insights into the autotransport process of a trimeric autotransporter, Yersinia Adhesin A (YadA). Molecular Microbiology.  ISSN 0950-382X.  111(3), s 844- 862 . doi: 10.1111/mmi.14195 Full text in Research Archive.
  • Finke, Sarah; Fagerlund, Annette; Smith, Veronika; Krogstad, Veronica; Zhang, Mimmi Jingxi; Saragliadis, Athanasios; Linke, Dirk; Nielsen-Leroux, Christina & Økstad, Ole Andreas (2019). Bacillus thuringiensis CbpA is a collagen binding cell surface protein under c-di-GMP control. The Cell Surface.  ISSN 2468-2330.  5, s 1- 12 . doi: 10.1016/j.tcsw.2019.100032 Full text in Research Archive.
  • Hatlem, Daniel; Trunk, Thomas; Linke, Dirk & Leo, Jack Christopher (2019). Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins. International Journal of Molecular Sciences.  ISSN 1422-0067.  20(9), s 1- 19 . doi: 10.3390/ijms20092129 Full text in Research Archive. Show summary
  • Meuskens, Ina; Saragliadis, Athanasios; Leo, Jack Christopher & Linke, Dirk (2019). Type V secretion systems: An overview of passenger domain functions. Frontiers in Microbiology.  ISSN 1664-302X.  10, s 1- 19 . doi: 10.3389/fmicb.2019.01163 Full text in Research Archive.
  • Micenková, Lenka; Bosak, Juraj; Kucera, Jiri; Hrala, Matej; Dolejsova, Tereza; Sedo, Ondrej; Linke, Dirk; Fiser, Radovan & Smajs, David (2019). Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains. Scientific Reports.  ISSN 2045-2322.  9(1), s 1- 12 . doi: 10.1038/s41598-019-47488-8 Full text in Research Archive.
  • Munoz Gonzalez, Florencia; Sycz, Gabriela; Alonso Paiva, Ivan M; Linke, Dirk; Zorreguieta, Angeles; Baldi, Pablo C & Ferrero, Mariana C (2019). The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection. Frontiers in Immunology.  ISSN 1664-3224.  10, s 1- 16 . doi: 10.3389/fimmu.2019.01775 Full text in Research Archive.
  • Saragliadis, Athanasios & Linke, Dirk (2019). Assay development for the discovery of small-molecule inhibitors of YadA adhesion to collagen. The Cell Surface.  ISSN 2468-2330.  5, s 1- 11 . doi: 10.1016/j.tcsw.2019.100025
  • Thibau, Arno; Dichter, Alexander A.; Vaca, Diana J.; Linke, Dirk; Goldman, Adrian & Kempf, Volkhard A.J. (2019). Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets. Medical Microbiology and Immmunology.  ISSN 0300-8584.  s 1- 21 . doi: 10.1007/s00430-019-00649-y Full text in Research Archive.
  • Tørresen, Ole K.; Star, Bastiaan; Mier, Pablo; Andrade-Navarro, Miguel A.; Bateman, Alex; Jarnot, Patryk; Gruca, Aleksandra; Grynberg, Marcin; Kajava, Andrey V.; Promponas, Vasilis J.; Anisimova, Maria; Jakobsen, Kjetill Sigurd & Linke, Dirk (2019). Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases. Nucleic Acids Research.  ISSN 0305-1048.  47(21), s 10994- 11006 . doi: 10.1093/nar/gkz841 Full text in Research Archive.
  • Weidensdorfer, Marko; Ishikawa, Masahito; Hori, Katsutoshi; Linke, Dirk; Djahanshiri, Bardya; Iruegas, Ruben; Ebersberger, Ingo; Riedel-Christ, Sara; Enders, Giulia; Leukert, Laura; Kraiczy, Peter; Rothweiler, Florian; Cinatl, Jindrich; Berger, Jürgen; Hipp, Katharina; Kempf, Volkhard A.J. & Gottig, Stephan (2019). The Acinetobacter trimeric autotransporter adhesin Ata controls key virulence traits of Acinetobacter baumannii. Virulence.  ISSN 2150-5594.  10(1), s 68- 81 . doi: 10.1080/21505594.2018.1558693 Full text in Research Archive.
  • Wróbel, Agnieszka Ewelina; Leo, Jack Christopher & Linke, Dirk (2019). Overcoming fish defences: The virulence factors of Yersinia ruckeri. Genes.  ISSN 2073-4425.  10(9), s 1- 20 . doi: 10.3390/genes10090700 Full text in Research Archive. Show summary
  • Leo, Jack Christopher & Linke, Dirk (2018). A unified model for BAM function that takes into account type Vc secretion and species differences in BAM composition. AIMS Microbiology.  ISSN 2471-1888.  4(3), s 455- 468 . doi: 10.3934/microbiol.2018.3.455 Full text in Research Archive. Show summary
  • Wrobel, Agnieszka; Ottoni, Claudio; Leo, Jack Christopher & Linke, Dirk (2018). pYR4 From a Norwegian Isolate of Yersinia ruckeri Is a Putative Virulence Plasmid Encoding Both a Type IV Pilus and a Type IV Secretion System. Frontiers in Cellular and Infection Microbiology.  ISSN 2235-2988.  8, s 1- 14 . doi: 10.3389/fcimb.2018.00373 Full text in Research Archive. Show summary
  • Meuskens, Ina; Michalik, Marcin; Chauhan, Nandini; Linke, Dirk & Leo, Jack Christopher (2017). A New Strain Collection for Improved Expression of Outer Membrane Proteins. Frontiers in Cellular and Infection Microbiology.  ISSN 2235-2988.  7 . doi: 10.3389/fcimb.2017.00464 Full text in Research Archive. Show summary
  • Michalik, Marcin; Rydmark, Marcella Orwick; Habeck, Michael; Alva, Vikram; Arnold, Thomas & Linke, Dirk (2017). An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins. PLOS ONE.  ISSN 1932-6203.  12(8) . doi: 10.1371/journal.pone.0182016 Full text in Research Archive.
  • Mühlenkamp, Melanie C.; Hallstrom, Teresia; Autenrieth, Ingo B.; Bohn, Erwin; Linke, Dirk; Rinker, Janina; Riesbeck, Kristian; Singh, Birendra; Leo, Jack Christopher; Hammerschmidt, Sven; Zipfel, Peter F. & Schütz, Monika (2017). Vitronectin binds to a specific stretch within the head region of yersinia adhesin a and thereby modulates yersinia enterocolitica host interaction. Journal of Innate Immunity.  ISSN 1662-811X.  9(1), s 33- 51 . doi: 10.1159/000449200 Full text in Research Archive.
  • Wrobel, Agnieszka; Ottoni, Claudio; Leo, Jack Christopher; Gulla, Snorre & Linke, Dirk (2017). The repeat structure of two paralogous genes, Yersinia ruckeri invasin (yrInv) and a “Y. ruckeri invasin-like molecule”, (yrIlm) sheds light on the evolution of adhesive capacities of a fish pathogen.. Journal of Structural Biology.  ISSN 1047-8477.  201(2), s 171- 183 . doi: 10.1016/j.jsb.2017.08.008
  • Curkić, I; Schütz, Monika; Oberhettinger, Philipp; Diard, P; Claassen, M; Linke, Dirk & Hardt, W (2016). Epitope-Tagged Autotransporters as Single-Cell Reporters for Gene Expression by a Salmonella Typhimurium wbaP Mutant. PLOS ONE.  ISSN 1932-6203.  11(5) . doi: 10.1371/journal.pone.0154828 Full text in Research Archive.
  • Fan, Enguo; Chauhan, Nandini; Udatha, D.B.R.K. Gupta; Leo, Jack Christopher & Linke, Dirk (2016). Type V secretion systems in bacteria, In Indira T. Kudva; Nancy A. Cornick; Paul J. Plummer; Qijing Zhang; Tracy L. Nicholson; John P. Bannantine & Bryan H. Bellaire (ed.),  Virulence Mechanisms of Bacterial Pathogens.  ASM International.  ISBN 9781555819279.  Chapter 11.  s 305 - 335
  • Koiwai, Kotaro; Hartmann, Marcus; Linke, Dirk; Lupas, Andrei & Hori, Katsutoshi (2016). Structural basis for toughness and flexibility in the C-terminal passenger domain of an acinetobacter trimeric autotransporter adhesin. Journal of Biological Chemistry.  ISSN 0021-9258.  291(8), s 3705- 3724 . doi: 10.1074/jbc.M115.701698 Full text in Research Archive.
  • Leo, Jack Christopher; Oberhettinger, Philipp; Yoshimoto, Shogo; Udatha, D.B.R.K. Gupta; Morth, Jens Preben; Schutz, Monika; Hori, Katsutoshi & Linke, Dirk (2016). Secretion of the Intimin passenger domain is driven by protein folding. Journal of Biological Chemistry.  ISSN 0021-9258.  291(38), s 20096- 20112 . doi: 10.1074/jbc.M116.731497 Full text in Research Archive.

View all works in Cristin

  • Linke, Dirk (2020). Biofilm-forming adhesins of the fish pathogen Yersinia ruckeri.
  • Ryoo, David; Orwick-Rydmark, Marcella; Pang, Y; Lundqvist, Daniel; Linke, Dirk & Gumbart, JC (2020). Quantitative Comparisons of Competing Models of Autotransporter Passenger-Domain Secretion.
  • Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2020). Analysing the fibronectin binding properties of Bartonella henselae adhesin A.
  • Chauhan, Nandini; Hatlem, Daniel; Orwick-Rydmark, Marcella; Schneider, Kenneth; Linke, Dirk & Leo, Jack Christopher (2019). Using the SpyCatcher-SpyTag technology for topology mapping of outer membrane proteins in Gram-negative bacteria.
  • Chowdhury, Sounak; Happonen, Lotta Johanna; Linke, Dirk & Malmström, Johan (2019). QUANTITATIVE AFFINITY-PURIFICATION AND SURFACE-ADSORPTION MASS SPECTROMETRY TO MAP STREPTOCOCCUS PYOGENES AND HUMAN PROTEIN INTERACTION.
  • Hatlem, Daniel; Chauhan, Nandini; Orwick-Rydmark, Marcella; Schneider, Kenneth; Flötenmeyer, Matthias; Van Rossum, Barth-J; Leo, Jack Christopher & Linke, Dirk (2019). Insights into the autotransport of a trimeric autotransporter.
  • Joudeh, Nadeem & Linke, Dirk (2019). Bio-engineered Palladium Nanoparticles.
  • Joudeh, Nadeem & Linke, Dirk (2019). Bio-engineered Pd Nanoparticles.
  • Joudeh, Nadeem; Røyne, Anja; Mikheenko, Pavlo & Linke, Dirk (2019). Bio-Engineered Palladium Nanoparticles (BEDPAN).
  • Kandanur, Sai Priya Sarma; Linke, Dirk & Leo, Jack Christopher (2019). Hairpin Formation and Passenger Secretion in the Inverse Autotransporter Intimin.
  • Leukert, L; Weidensdorfer, M; Djahanshiri, Bardya; Linke, Dirk; Kempf, Volkhard A.J. & Gottig, Stephan (2019). The Acinetobacter Trimeric Autotransporter Adhesin Ata Controls Key Virulence Traits of Acinetobacter baumannii.
  • Leva, Juan; Meuskens, Ina; Gibson, Timothy M.; Linke, Dirk & Millner, Paul (2019). Biosensors for pathogen detection.
  • Linke, Dirk (2019). Autotransporter Adhesins in the fish pathogen Yersinia ruckeri.
  • Linke, Dirk (2019). Insights into the autotransport process of a trimeric autotransporter, YadA.
  • Linke, Dirk (2019). The Gram-Negative Bacterial Cell Surface: How to Study Its Protein Components and How to Remove Endotoxin.
  • Linke, Dirk (2019). Type V secretion: membrane transport and anchoring of bacterial adhesins.
  • Linke, Dirk & Joudeh, Nadeem (2019, 15. desember). Centre for Digital Life helps researchers right out of the gate (Senter for digitalt liv hjelper forskere ut av innovasjonsstartgropa). [Internett].  Center For Digital Life - Website.
  • Linke, Dirk & Saragliadis, Athanasios (2019). Bacterial adhesion to living and non-living surfaces.
  • Meuskens, Ina; Higson, Seamus & Linke, Dirk (2019). Innovative training networks: a new way of collaboration-propped PhD training. Medical Microbiology and Immmunology.  ISSN 0300-8584.  209, s 215- 216 . doi: 10.1007/s00430-019-00647-0
  • Meuskens, Ina; Leva, Juan; Millner, Paul & Linke, Dirk (2019). Differential Adhesion of Trimeric Autotransporter Adhesins to Extracellular Matrix Proteins.
  • Meuskens, Ina & Linke, Dirk (2019). Binding of Yersinia Ahesin A to ECM molecules: a biosensor approach.
  • Mikheenko, Pavlo; Mikheenko, Iryna; Joudeh, Nadeem; Claxton, J. B.; Røyne, Anja & Linke, Dirk (2019). Imaging magnetism of biologically produced palladium nanoparticles.
  • Orwick-Rydmark, Marcella; Chauhan, Nandini; Van Rossum, Barth-J & Linke, Dirk (2019). Towards the structure of the YadA anchor domain in the native membrane.
  • Orwick-Rydmark, Marcella; Lindemann, Florian; Chauhan, Nandini; Yarava, J; Oschkinat, Hartmut; Van Rossum, Barth-J & Linke, Dirk (2019). In situ structural and dynamic analysis of a membrane protein.
  • Orwick-Rydmark, Marcella & Linke, Dirk (2019, 05. juni). A novel antibiotic idea: Preventing bacterial stickiness. [Internett].  international.
  • Orwick-Rydmark, Marcella; Van Rossum, Barth-J; Oschkinat, Hartmut & Linke, Dirk (2019). Towards the in situ structure of the Yersinia Adhesin A membrane anchor domain.
  • Røsjø, Bjarne; Orwick-Rydmark, Marcella; Linke, Dirk; Leo, Jack Christopher & Hatlem, Daniel (2019, 13. mai). Ny antibiotika-idé: Vil hindre bakteriene i å feste seg. [Internett].  TITAN.NO.
  • Saragliadis, Athanasios & Linke, Dirk (2019). Assay development for the discovery of small-molecule inhibitors of YadA adhesion to collagen.
  • Saragliadis, Athanasios & Linke, Dirk (2019). Screening for small-molecule inhibitors of YadA adhesion to collagen.
  • Thibau, Arno; Vaca, Diana; Linke, Dirk; Ballhorn, Wibke & Kempf, Volkhard A.J. (2019). Analysing the Fibronectin Binding Domain of the Bartonella henselae Adhesin A.
  • Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2019). Analysing the fibronectin binding domain of the Bartonella henselae adhesin A.
  • Tietgen, M; Weidensdorfer, M; Djahanshiri, Bardya; Linke, Dirk; Kempf, Volkhard A.J. & Gottig, Stephan (2019). Virulence of Acinetobacter baumannii depends on the Acinetobacter trimeric autotransporter adhesin Ata.
  • Tietgen, M; Weidensdorfer, M; Leukert, L; Djahanshiri, Bardya; Iruegas, R; Ebersberger, Ingo; Linke, Dirk; Kempf, Volkhard A.J. & Gottig, Stephan (2019). Virulence of Acinetobacter baumannii depends on the Acinetobacter trimeric autotransporter adhesin (Ata).
  • Balusek, Curtis; Linke, Dirk & Gumbart, JC (2018). The effect of beta-barrel geometry on ion conduction through Escherichia coli OmpX.
  • Hatlem, Daniel; Chauhan, Nandini; Rydmark, Marcella Orwick; Schneider, Kenneth; Floetenmeyer, Matthias; Leo, Jack Christopher & Linke, Dirk (2018). Insights into the autotransporter process of a trimeric autotransporter, Yersinia Adhesin A (YadA).
  • Hatlem, Daniel & Linke, Dirk (2018). Insights into the autotransporter process of a trimeric autotransporter, Yersinia Adhesin A (YadA).
  • Joudeh, Nadeem; Leo, Jack Christopher; Torgeman, Eric & Linke, Dirk (2018). Mechanism of Palladium and Gold uptake and reduction in E. coli.
  • Joudeh, Nadeem & Linke, Dirk (2018, 20. oktober). BEDPAN - Nanoparticles from Bacteria. [Internett].  Digital Life Website.
  • Khalil, Hawzeen; Øgaard, Jonas; Linke, Dirk & Leo, Jack Christopher (2018). Co-aggregation properties of trimeric autotransporter adhesins.
  • Leo, Jack Christopher; Oberhettinger, Philipp; Schuetz, Monika & Linke, Dirk (2018). Type Ve secretion: the mechanism of inverse autotransport.
  • Leo, Jack Christopher; Schütz, Monika & Linke, Dirk (2018). Type Ve Secretion in Enterobacteria.
  • Linke, Dirk (2018). Structural Biology of Membrane Proteins: Expression Tricks, and to Solubilize or Not to Solubilize.
  • Linke, Dirk (2018). Trimeric Autotransporter Adhesins and routes to their inhibition.
  • Linke, Dirk & Meuskens, Ina (2018). Adhesion of Yersinia Adhesin A to Collagen.
  • Linke, Dirk & Saragliadis, Athanasios (2018). Trimeric Autotransporter Adhesins - Understanding adhesive function and screening for inhibitors.
  • Linke, Dirk & Saragliadis, Athanasios (2018). Trimeric Autotransporter Adhesins - understanding adhesive function and screening for inhibitors.
  • Wrobel, Agnieszka; Ottoni, Claudio; Leo, Jack Christopher & Linke, Dirk (2018). The repeat structure of two paralogous genes, Yersinia ruckeri invasin (yrInv) and a “Y. ruckeri invasin-like molecule”, (yrIlm) sheds light on the evolution of adhesive capacities of a fish pathogen.
  • Wrobel, Agnieszka; Saragliadis, Athanasios; Leo, Jack Christopher; Ottoni, Claudio & Linke, Dirk (2018). Type Ve autotransporters in Yersinia ruckeri.
  • Økstad, Ole Andreas Løchen & Linke, Dirk (2018). Hvor farlig er antibiotikaresistens?. Ingeniørenes Stemme.  Vinter 2018, s 37- 37
  • Hatlem, Daniel; Leo, Jack Christopher; Saragliadis, Athanasios; Krengel, Ute & Linke, Dirk (2017). Bacterial adhesion: Characterization of trimeric autotransporter binding.
  • Joudeh, Nadeem; Leo, Jack Christopher; Torgeman, Eric; Mikheenko, Pavlo & Linke, Dirk (2017). Mechanism of Palladium and Gold uptake and transport in E. coli.
  • Joudeh, Nadeem & Linke, Dirk (2017). Mechanism of palladium and gold uptake and transport in E. coli.
  • Leo, Jack Christopher & Linke, Dirk (2017). Inverse autotransport: the mechanism of type Ve secretion​..
  • Leo, Jack Christopher; Oberhettinger, Philipp; Schütz, Monika & Linke, Dirk (2017). Inverse autotransport: the mechanism of type Ve secretion.
  • Linke, Dirk (2017). Do we have to purify membrane proteins? Solid-state NMR in the native membrane.
  • Linke, Dirk (2017). Trimeric Autotransporter Evolution.
  • Linke, Dirk (2017). Trimeric Autotrasnporter Adhesins: Stucture, Function, and Evolution.
  • Linke, Dirk (2017). Trimeric autotransporter adhesins (TAAs) and routes to their inhibition.
  • Linke, Dirk (2017). Type Ve secretion in Gram-negative Bacteria.
  • Liskiewicz, Krystyna; Wrobel, Agnieszka; Leo, Jack Christopher & Linke, Dirk (2017). Identification of potential adhesin receptors from Yersinia ruckeri.
  • Michalik, Marcin; Orwick-Rydmark, Marcella; Arnold, Thomas; Habeck, Michael & Linke, Dirk (2017). An evolutionarily conserved motif forms a folding core in Outer membrane proteins.
  • Orwick-Rydmark, Marcella; Chauhan, Nandini; Shahid, Shakeel & Linke, Dirk (2017). Solid-state NMR studies on Yersinia YadA: from autotransport to drug screening.
  • Saragliadis, Athanasios & Linke, Dirk (2017). STRUCTURE-FUNCTION RELATIONSHIP IN BACTERIAL ADHESINS.
  • Schneider, Kenneth; Haugen, Håvard Jostein & Linke, Dirk (2017). Assay Development: Adhesin Interaction with Implant Materials.
  • Torgeman, Eric; Linke, Dirk & Leo, Jack Christopher (2017). Biosynthesis of gold and palladium nanoparticles via bacteria.
  • Weidensdorfer, M; Linke, Dirk; Kempf, Volkhard A.J. & Gottig, Stephan (2017). Establishing of a dynamic human ex vivo infection model for analyzing endothelial adherence of Acinetobacter baumannii.
  • Wrobel, Agnieszka; Leo, Jack Christopher; Ottoni, Claudio; Gulla, Snorre & Linke, Dirk (2017). Comparative structure-function analysis of adhesins from different Yersinia ruckeri strains.
  • Wrobel, Agnieszka & Linke, Dirk (2017). The repeat structure of two paralogous invasin genes from Yersinia ruckeri sheds light on the evolution of adhesive capacities of a Fish pathogen.
  • Wrobel, Agnieszka; Ottoni, Claudio; Leo, Jack Christopher & Linke, Dirk (2017). IDENTIFICATION AND CHARACTERIZATION OF INVERSE AUTOTRANSPORTERS FROM A FISH PATHOGEN, YERSINIA RUCKERI.
  • Wrobel, Agnieszka; Ottoni, Claudio; Leo, Jack Christopher & Linke, Dirk (2017). IDENTIFICATION AND CHARACTERIZATION OF INVERSE AUTOTRANSPORTERS FROM A FISH PATHOGEN, YERSINIA RUCKERI..
  • Hatlem, Daniel; Kempf, Volkhard A.J.; Krengel, Ute & Linke, Dirk (2016). Bacterial adhesion: Characterization of trimeric autotransporter binding.
  • Leo, Jack Christopher & Linke, Dirk (2016). Inverse autotransport: surface export of Intimin and other type Ve secretion systems.
  • Leo, Jack Christopher & Linke, Dirk (2016). Secretion of the Intimin Passenger Domain Is Driven by Protein Folding..
  • Leo, Jack Christopher & Linke, Dirk (2016). Type Ve secretion - inverse autotransport​.
  • Leo, Jack Christopher; Oberhettinger, Philipp; Schütz, Monika; Hori, Katsutoshi; Yoshimoto, Shogo & Linke, Dirk (2016). The secretion of the Intimin passenger is driven by protein folding.
  • Leo, Jack Christopher; Yoshimoto, Shogo; Oberhettinger, Philipp; Schütz, Monika; Hori, Katsutoshi & Linke, Dirk (2016). The secretion of the Intimin passenger domain is driven by protein folding..
  • Linke, Dirk (2016, 10. februar). NRK Forbrukerinspektørene. [TV].  NRK. Show summary

View all works in Cristin

Published Oct. 16, 2013 9:37 AM - Last modified Jan. 29, 2015 11:58 AM

Projects

No ongoing projects