My research group focusses on the structure and function of the bacterial cell surface. Currently, we work on three main topics:
- Bacterial Adhesion: How do bacteria stick to surfaces, or in the case of pathogens, to host cells?
- Membrane transport: how are adhesion molecules transported to the cell surface? And can this process be inhibited with novel antimicrobial substances?
- Vaccines and Biomarkers: can we exploit bacterial surface proteins as vaccine candidates or as biomarkers, e.g. for improved clinical diagnostics?
Our work is typically comparative – we do not work on a single pathogenic “pet” organism, but instead compare related surface proteins from different species, studying their similarities and subtle differences. Our work is also interdisciplinary – we use methods from bioinformatics, structural biology and biophysics on top of classical methods from microbiology, molecular biology and biochemistry.
- MBV 3060 (Basic Microbiology)
- MBV 4910 (iGEM Competition)
Higher education and employment history
- since 2015 Full Professor, Department of Biosciences, UiO
- since 2013 Associate Professor, Department of Biosciences, UiO
- 2010 Habilitation, Department of Biology, University of Tübingen
- 2007-2013 Project Leader, Max Planck Institute for Developmental Biology, Tübingen
- 2003-2007 PostDoc, Max Planck Institute for Developmental Biology, Tübingen
- 2002 PhD, Department of Chemistry, TU Berlin
- 1991-1997, undergraduate studies in Biochemistry, FU Berlin
- 2009 Young Academics Award from the German Society for Hygiene and Microbiology
- 2008 and 2009 two 1-year stipends from the Bill & Melinda Gates Foundation
- Advisory Board Member, Molecular Microbiology (Wiley)
- Review Editor, Journal of Biological Chemistry
- Review Editor, Frontiers in Microbiology