Dirk Linke

Professor - Seksjon for genetikk og evolusjonsbiologi

English version of this page

E-post dirk.linke@ibv.uio.no

Telefon +47 22857654

Rom 3517

Brukernavn

Besøksadresse Blindernveien 31 0371 Oslo

Postadresse Postboks 1066 Blindern 0316 Oslo

Last ned visittkort

Academic Interests

My research group focusses on the structure and function of the bacterial cell surface. Currently, we work on three main topics:

Bacterial Adhesion: How do bacteria stick to surfaces, or in the case of pathogens, to host cells?
Membrane transport: how are adhesion molecules transported to the cell surface? And can this process be inhibited with novel antimicrobial substances?
Vaccines and Biomarkers: can we exploit bacterial surface proteins as vaccine candidates or as biomarkers, e.g. for improved clinical diagnostics?

Our work is typically comparative – we do not work on a single pathogenic “pet” organism, but instead compare related surface proteins from different species, studying their similarities and subtle differences. Our work is also interdisciplinary – we use methods from bioinformatics, structural biology and biophysics on top of classical methods from microbiology, molecular biology and biochemistry.

Teaching

MBV 3060 (Basic Microbiology)
MBV 4910 (iGEM Competition)
...

Higher education and employment history

since 2015 Full Professor, Department of Biosciences, UiO
since 2013 Associate Professor, Department of Biosciences, UiO
2010 Habilitation, Department of Biology, University of Tübingen
2007-2013 Project Leader, Max Planck Institute for Developmental Biology, Tübingen
2003-2007 PostDoc, Max Planck Institute for Developmental Biology, Tübingen
2002 PhD, Department of Chemistry, TU Berlin
1991-1997, undergraduate studies in Biochemistry, FU Berlin

Honoraria

2009 Young Academics Award from the German Society for Hygiene and Microbiology
2008 and 2009 two 1-year stipends from the Bill & Melinda Gates Foundation
...

Appointments

Advisory Board Member, Molecular Microbiology (Wiley)
Review Editor, Journal of Biological Chemistry
Review Editor, Frontiers in Microbiology

Sande, Maria; Ferreira, Debora; Rodrigues, Joana; Melo, Luis; Linke, Dirk & Silva, Carla [Vis alle 9 forfattere av denne artikkelen] (2022). Electrochemical Aptasensor for the Detection of the Key Virulence Factor YadA of Yersinia enterocolitica. Biosensors. ISSN 2079-6374. 12(8). doi: 10.3390/bios12080614.
Hermansen, Simen; Ryoo, David; Orwick-Rydmark, Marcella; Saragliadis, Athanasios; Gumbart, James C & Linke, Dirk (2022). The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli. Frontiers in Molecular Biosciences. ISSN 2296-889X. 9. doi: 10.3389/fmolb.2022.918480. Fulltekst i vitenarkiv
Vaca, Diana; Thibau, Arno; Leisegang, Matthias; Malmström, Johan; Linke, Dirk & Eble, Johannes A. [Vis alle 10 forfattere av denne artikkelen] (2022). Interaction of Bartonella henselae with Fibronectin Represents the Molecular Basis for Adhesion to Host Cells. Microbiology spectrum. ISSN 2165-0497. 10(3). doi: 10.1128/spectrum.00598-22. Fulltekst i vitenarkiv
Joudeh, Nadeem & Linke, Dirk (2022). Nanoparticle classification, physicochemical properties, characterization, and applications: a comprehensive review for biologists. Journal of Nanobiotechnology. ISSN 1477-3155. 20. doi: 10.1186/s12951-022-01477-8. Fulltekst i vitenarkiv
Thibau, Arno; Hipp, K.; Vaca, Diana; Chowdhury, Sounak; Malmström, Johan & Saragliadis, Athanasios [Vis alle 9 forfattere av denne artikkelen] (2022). Long-read sequencing reveals genetic adaptation of Bartonella adhesin A among different Bartonella henselae isolates. Frontiers in Microbiology. ISSN 1664-302X. 13. doi: 10.3389/fmicb.2022.838267. Fulltekst i vitenarkiv
Hermansen, Simen; Linke, Dirk & Leo, Jack Christopher (2022). Transmembrane β-barrel proteins of bacteria: From structure to function. I Donev, Rossen (Red.), Membrane Proteins. Academic Press. ISSN 978-0-323-98895-7. s. 113–161. doi: 10.1016/bs.apcsb.2021.07.002.
Meuskens, Ina; Leva-Bueno, Juan; Millner, Paul; Schütz, Monika; Peyman, Sally & Linke, Dirk (2022). The Trimeric Autotransporter Adhesin YadA of Yersinia enterocolitica Serotype O:9 Binds Glycan Moieties. Frontiers in Microbiology. ISSN 1664-302X. doi: 10.3389/fmicb.2021.738818.
Michalik, Marcin; Djahanshiri, Bardya; Leo, Jack C. & Linke, Dirk (2022). An Update on "Reverse Vaccinology": The Pathway from Genomes and Epitope Predictions to Tailored, Recombinant Vaccines. Methods in molecular biology. ISSN 1064-3745. 2412, s. 45–71. doi: 10.1007/978-1-0716-1892-9_4. Fulltekst i vitenarkiv
Beal, J.; Saragliadis, Athanasios & Linke, Dirk (2021). Comparative analysis of three studies measuring fluorescence from engineered bacterial genetic constructs. PLOS ONE. ISSN 1932-6203. 16(6). doi: 10.1371/journal.pone.0252263. Fulltekst i vitenarkiv
Mekasha, Sophanit & Linke, Dirk (2021). Secretion Systems in Gram-Negative Bacterial Fish Pathogens. Frontiers in Microbiology. ISSN 1664-302X. 12. doi: 10.3389/fmicb.2021.782673. Fulltekst i vitenarkiv
Chowdhury, Sounak; Khakzad, Hamed; Bergdahl, Gizem Ertürk; Lood, Rolf; Ekström, Simon & Linke, Dirk [Vis alle 9 forfattere av denne artikkelen] (2021). Streptococcus pyogenes Forms Serotype- and Local Environment-Dependent Interspecies Protein Complexes. mSystems. ISSN 2379-5077. 6(5). doi: 10.1128/mSystems.00271-21. Fulltekst i vitenarkiv
Campana Perilla, Ana Lucia; Joudeh, Nadeem; Linke, Dirk & Mikheenko, Pavlo (2021). Magnetic decoration of Escherichia coli loaded with Palladium nanoparticles , 2021 IEEE 10th International Conference on “Nanomaterials: Applications & Properties” (NAP – 2021). IEEE. ISSN 978-1-6654-3907-7. s. NCI01-1–NCI01-5. doi: 10.1109/NAP51885.2021.9568523. Fulltekst i vitenarkiv
Zhang, Zijian; Ryoo, David; Balusek, Curtis; Acharya, Atanu; Rydmark, Marcella Orwick & Linke, Dirk [Vis alle 7 forfattere av denne artikkelen] (2021). Inward-facing glycine residues create sharp turns in β-barrel membrane proteins. Biochimica et Biophysica Acta - Biomembranes. ISSN 0005-2736. 1863(10). doi: 10.1016/j.bbamem.2021.183662.
Joudeh, Nadeem; Saragliadis, Athanasios; Schulz, Christian; Voigt, Andre; Almaas, Eivind & Linke, Dirk (2021). Transcriptomic Response Analysis of Escherichia coli to Palladium Stress. Frontiers in Microbiology. ISSN 1664-302X. 12. doi: 10.3389/fmicb.2021.741836. Fulltekst i vitenarkiv
van Belkum, Alex; Almeida, Carina; Bardiaux, Benjamin; Barrass, Sarah V.; Butcher, Sarah J. & Çaykara, Tuğçe [Vis alle 34 forfattere av denne artikkelen] (2021). Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens. Diagnostics (Basel). ISSN 2075-4418. 11(7), s. 1–22. doi: 10.3390/diagnostics11071259. Fulltekst i vitenarkiv
Wimmi, Stephan; Balinovic, Alexander; Jeckel, Hannah; Selinger, Lisa; Lampaki, Dimitrios & Eisemann, Emma [Vis alle 11 forfattere av denne artikkelen] (2021). Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH. Nature Communications. ISSN 2041-1723. 12(1), s. 1–14. doi: 10.1038/s41467-021-21863-4. Fulltekst i vitenarkiv
Rooke, Jessica; Icke, Christopher; Wells, Timothy; Rossiter, Amanda; Browning, Douglas & Morris, Faye [Vis alle 12 forfattere av denne artikkelen] (2021). BamA and BamD Are Essential for the Secretion of Trimeric Autotransporter Adhesins. Frontiers in Microbiology. ISSN 1664-302X. 12. doi: 10.3389/fmicb.2021.628879. Fulltekst i vitenarkiv
Beal, J; Saragliadis, Athanasios & Linke, Dirk (2020). Robust estimation of bacterial cell count from optical density. Communications Biology. ISSN 2399-3642. 3(1). doi: 10.1038/s42003-020-01127-5. Fulltekst i vitenarkiv
Claxton, James Benedict; Joudeh, Nadeem; Røyne, Anja; Linke, Dirk & Mikheenko, Pavlo (2020). Sequential magnetic mapping of bacteria loaded with Pd-Fe nanoparticles , 2020 IEEE 10th International Conference on “Nanomaterials: Applications & Properties” (NAP – 2020). IEEE. ISSN 978-1-7281-8506-4. s. 01NIC01-1–01NIC01-5. doi: 10.1109/NAP51477.2020.9309619. Fulltekst i vitenarkiv
Campaña Perilla, Ana Lucia; Joudeh, Nadeem; Høyer, Henrik; Røyne, Anja; Linke, Dirk & Mikheenko, Pavlo (2020). Probing van der Waals and magnetic forces in bacteria with magnetic nanoparticles, 2020 IEEE 10th International Conference on “Nanomaterials: Applications & Properties” (NAP – 2020). IEEE. ISSN 978-1-7281-8506-4. s. 01NSSA03-1–01NSSA03-5. doi: 10.1109/NAP51477.2020.9309722. Fulltekst i vitenarkiv
Stephan, Mareike; Broeker, Nina; Saragliadis, Athanasios; Roos, Norbert; Linke, Dirk & Barbirz, Stefanie (2020). In vitro Analysis of O-Antigen-Specific Bacteriophage P22 Inactivation by Salmonella Outer Membrane Vesicles. Frontiers in Microbiology. ISSN 1664-302X. 11. doi: 10.3389/fmicb.2020.510638. Fulltekst i vitenarkiv
Hatlem, Daniel; Trunk, Thomas; Linke, Dirk & Leo, Jack Christopher (2020). Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins. I Leitao, JH (Red.), Microbial Virulence Factors. MDPI. ISSN 978-3-03936-946-1. s. 371–400. doi: 10.3390/ijms20092129. Fulltekst i vitenarkiv
Wróbel, Agnieszka Ewelina; Saragliadis, Athanasios; Pérez-Ortega, Jesús; Sittman, Carolin; Göttig, Stephan & Liskiewicz, Krystyna Anna [Vis alle 11 forfattere av denne artikkelen] (2020). The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. Environmental Microbiology. ISSN 1462-2912. 22(7), s. 2939–2955. doi: 10.1111/1462-2920.15051. Fulltekst i vitenarkiv
Ryoo, David; Rydmark, Marcella Orwick; Pang, Yui Tik; Lundquist, Karl P; Linke, Dirk & Gumbart, James C (2020). BamA is required for autotransporter secretion. Biochimica et Biophysica Acta - General Subjects. ISSN 0304-4165. 1864(7), s. 1–8. doi: 10.1016/j.bbagen.2020.129581. Fulltekst i vitenarkiv
Thibau, Arno; Dichter, Alexander A.; Vaca, Diana J.; Linke, Dirk; Goldman, Adrian & Kempf, Volkhard A.J. (2019). Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets. Medical Microbiology and Immmunology. ISSN 0300-8584. 209, s. 243–263. doi: 10.1007/s00430-019-00649-y. Fulltekst i vitenarkiv
Aoki, S.; Yoshimoto, Shogo; Ishikawa, M; Linke, Dirk; Lupas, Andrei & Hori, Katsutoshi (2019). Native display of a huge homotrimeric protein fiber on the cell surface after precise domain deletion. Journal of Bioscience and Bioengineering. ISSN 1389-1723. s. 1–6. doi: 10.1016/j.jbiosc.2019.09.022.
Saragliadis, Athanasios & Linke, Dirk (2019). Assay development for the discovery of small-molecule inhibitors of YadA adhesion to collagen. The Cell Surface. ISSN 2468-2330. 5, s. 1–11. doi: 10.1016/j.tcsw.2019.100025. Fulltekst i vitenarkiv
Finke, Sarah; Fagerlund, Annette; Smith, Veronika; Krogstad, Veronica; Zhang, Mimmi Jingxi & Saragliadis, Athanasios [Vis alle 9 forfattere av denne artikkelen] (2019). Bacillus thuringiensis CbpA is a collagen binding cell surface protein under c-di-GMP control. The Cell Surface. ISSN 2468-2330. 5, s. 1–12. doi: 10.1016/j.tcsw.2019.100032. Fulltekst i vitenarkiv
Tørresen, Ole K.; Star, Bastiaan; Mier, Pablo; Andrade-Navarro, Miguel A.; Bateman, Alex & Jarnot, Patryk [Vis alle 13 forfattere av denne artikkelen] (2019). Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases. Nucleic Acids Research (NAR). ISSN 0305-1048. 47(21), s. 10994–11006. doi: 10.1093/nar/gkz841. Fulltekst i vitenarkiv
Munoz Gonzalez, Florencia; Sycz, Gabriela; Alonso Paiva, Ivan M; Linke, Dirk; Zorreguieta, Angeles & Baldi, Pablo C [Vis alle 7 forfattere av denne artikkelen] (2019). The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection. Frontiers in Immunology. ISSN 1664-3224. 10, s. 1–16. doi: 10.3389/fimmu.2019.01775. Fulltekst i vitenarkiv
Wróbel, Agnieszka Ewelina; Leo, Jack Christopher & Linke, Dirk (2019). Overcoming fish defences: The virulence factors of Yersinia ruckeri. Genes. ISSN 2073-4425. 10(9), s. 1–20. doi: 10.3390/genes10090700. Fulltekst i vitenarkiv Vis sammendrag
Yersinia ruckeri is the causative agent of enteric redmouth disease, a bacterial infection of marine and freshwater fish. The disease mainly affects salmonids, and outbreaks have significant economic impact on fish farms all over the world. Vaccination routines are in place against the major serotypes of Y. ruckeri but are not effective in all cases. Despite the economic importance of enteric redmouth disease, a detailed molecular understanding of the disease is lacking. A considerable number of mostly omics-based studies have been performed in recent years to identify genes related to Y. ruckeri virulence. This review summarizes the knowledge on Y. ruckeri virulence factors. Understanding the molecular pathogenicity of Y. ruckeri will aid in developing more efficient vaccines and antimicrobial compounds directed against enteric redmouth disease.
Weidensdorfer, Marko; Ishikawa, Masahito; Hori, Katsutoshi; Linke, Dirk; Djahanshiri, Bardya & Iruegas, Ruben [Vis alle 17 forfattere av denne artikkelen] (2019). The Acinetobacter trimeric autotransporter adhesin Ata controls key virulence traits of Acinetobacter baumannii. Virulence. ISSN 2150-5594. 10(1), s. 68–81. doi: 10.1080/21505594.2018.1558693. Fulltekst i vitenarkiv
Micenková, Lenka; Bosak, Juraj; Kucera, Jiri; Hrala, Matej; Dolejsova, Tereza & Sedo, Ondrej [Vis alle 9 forfattere av denne artikkelen] (2019). Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains. Scientific Reports. ISSN 2045-2322. 9(1), s. 1–12. doi: 10.1038/s41598-019-47488-8. Fulltekst i vitenarkiv
Meuskens, Ina; Saragliadis, Athanasios; Leo, Jack Christopher & Linke, Dirk (2019). Type V secretion systems: An overview of passenger domain functions. Frontiers in Microbiology. ISSN 1664-302X. 10, s. 1–19. doi: 10.3389/fmicb.2019.01163. Fulltekst i vitenarkiv
Hatlem, Daniel; Trunk, Thomas; Linke, Dirk & Leo, Jack Christopher (2019). Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins. International Journal of Molecular Sciences. ISSN 1661-6596. 20(9), s. 1–19. doi: 10.3390/ijms20092129. Fulltekst i vitenarkiv Vis sammendrag
The SpyCatcher-SpyTag system was developed seven years ago as a method for protein ligation. It is based on a modified domain from a Streptococcus pyogenes surface protein (SpyCatcher), which recognizes a cognate 13-amino-acid peptide (SpyTag). Upon recognition, the two form a covalent isopeptide bond between the side chains of a lysine in SpyCatcher and an aspartate in SpyTag. This technology has been used, among other applications, to create covalently stabilized multi-protein complexes, for modular vaccine production, and to label proteins (e.g., for microscopy). The SpyTag system is versatile as the tag is a short, unfolded peptide that can be genetically fused to exposed positions in target proteins; similarly, SpyCatcher can be fused to reporter proteins such as GFP, and to epitope or purification tags. Additionally, an orthogonal system called SnoopTag-SnoopCatcher has been developed from an S. pneumoniae pilin that can be combined with SpyCatcher-SpyTag to produce protein fusions with multiple components. Furthermore, tripartite applications have been produced from both systems allowing the fusion of two peptides by a separate, catalytically active protein unit, SpyLigase or SnoopLigase. Here, we review the current state of the SpyCatcher-SpyTag and related technologies, with a particular emphasis on their use in vaccine development and in determining outer membrane protein localization and topology of surface proteins in bacteria.
Chauhan, Nandini; Hatlem, Daniel; Rydmark, Marcella Orwick; Schneider, Kenneth; Flötenmeyer, Matthias & Van Rossum, Barth-J [Vis alle 8 forfattere av denne artikkelen] (2019). Insights into the autotransport process of a trimeric autotransporter, Yersinia Adhesin A (YadA). Molecular Microbiology. ISSN 0950-382X. 111(3), s. 844–862. doi: 10.1111/mmi.14195. Fulltekst i vitenarkiv

Se alle arbeider i Cristin

Linke, Dirk (2022). How to apply for a PhD position... and how not to!
Hatlem, Daniel; Linke, Dirk Bernd Kurt & Andersen, Elisabeth K. (2022). Forskerprosjekt på antibiotika og blodforgiftning. [Internett]. Website Oslo Cancer Cluster.
Wimmi, Stephan; Balinovic, Alexander; Jeckel, Hannah; Selinger, Lisa; Lampaki, Dimitrios & Eisemann, Emma [Vis alle 11 forfattere av denne artikkelen] (2021). Author Correction: Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH (Nature Communications, (2021), 12, 1, (1625), 10.1038/s41467-021-21863-4). Nature Communications. ISSN 2041-1723. 12(1). doi: 10.1038/s41467-021-23080-5.
Mertes, Verena; Saragliadis, Athanasios; Ciani, Elia; Linke, Dirk; Colquhoun, Duncan J & Winther-Larsen, Hanne Cecilie (2021). Characterization of membrane vesicles from fish pathogens, their role in virulence and possible function as a vaccine in aquaculture.
Linke, Dirk (2021). Developing inhibitors that block adhesin-collagen interactions.
Linke, Dirk (2021). #FEMSmicroBlog: The balancing act between basic and applied science.
Fan, Enguo & Linke, Dirk (2021). the exchange program MISC - Options for internships at PMUC (with descriptions of current projects).
Hori, Katsutoshi & Linke, Dirk (2021). the exchange program MISC - Options for internships at Nagoya University (with descriptions of current projects by students).
Linke, Dirk; Økstad, Ole Andreas; Haugen, Håvard Jostein & Winther-Larsen, Hanne Cecilie (2021). The exchange program MISC - Options for internships at the University of Oslo (with descriptions of current projects).
Campana Perilla, Ana Lucia; Joudeh, Nadeem; Linke, Dirk & Mikheenko, Pavlo (2021). Magnetic decoration of Escherichia coli loaded with Palladium nanoparticles .
Chowdhury, Sounak; Linke, Dirk; Happonen, Lotta Johanna & Malmström, Johan (2021). Streptococcus pyogenes forms M protein specific host-environment dependent protein complexes.
Thibau, Arno; Linke, Dirk & Kempf, Volkhard A.J. (2021). Analysing the fibronectin binding properties and genomic variation of Bartonella henselae adhesin.
Leva-Bueno, Juan; Meuskens, Ina; Linke, Dirk; Millner, Paul & Peyman, Sally (2021). Impedimetric biosensor based on extracellular matrix protein-adhesin interaction.
Meuskens, Ina; Leva-Bueno, Juan; Millner, Paul; Schütz, Monika; Peyman, Sally & Linke, Dirk (2021). The Trimeric Autotransporter Adhesin YadA of Yersinia binds to glycan moieties.
Vaca, Diana; Thibau, Arno; Linke, Dirk; Happonen, Lotta Johanna; Malmström, Johan & Kempf, Volkhard A.J. (2021). Interaction between Bartonella adhesin A and fibronectin in bacterial adherence to human endothelial cells.
Linke, Dirk (2021). Using LPS-Binding Peptides To Detect Endotoxins.
Chowdhury, Sounak; Linke, Dirk; Happonen, Lotta Johanna & Malmström, Johan (2021). Streptococcus Pyogenes Forms M Protein Specific Host-microenvironment Dependent Protein Complexes.
Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2021). Analysing the Fibronectin Binding Properties of Bartonella henselae Adhesin A.
Leva, Juan; Meuskens, Ina; Linke, Dirk; Peyman, Sally & Millner, Paul (2021). Novel Electrochemical Biosensor for Pathogen Detection Based on Extracellular Matrix (ECM) Protein - Adhesin Interaction.
Meuskens, Ina & Linke, Dirk (2021). The Trimeric Autotransporter Adhesin YadA of Yersinia Binds to Glycan Moieties.
Vaca, Diana; Happonen, Lotta Johanna; Goldman, Adrian & Linke, Dirk (2021). Bacterial and Viral Adhesion; Two Sides of the Same Coin?
Butcher, Sarah Jane & Linke, Dirk (2021). Viral and Bacterial Adhesion - examples from current ViBrANT research.
Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2021). Analysing the fibronectin binding properties of B. henselae adhesin A .
Meuskens, Ina; Michalik, Marcin; Chauhan, Nandini; Linke, Dirk & Leo, Jack Christopher (2020). Corrigendum: A New Strain Collection for Improved Expression of Outer Membrane Proteins (Frontiers in Cellular and Infection Microbiology, (2017), 7, (464), 10.3389/fcimb.2017.00464). Frontiers in Cellular and Infection Microbiology. ISSN 2235-2988. 10. doi: 10.3389/fcimb.2020.00220.
Linke, Dirk (2020). LPS-Binding Peptides: New Tools for Endotoxin Detection and Removal?
Linke, Dirk (2020). Norsk kobber inn i kampen mot koronaviruset: verdens første selvrensende munnbind. [Internett]. Nordox website.
Linke, Dirk (2020). Dette munnbindet skal drepe koronaviruset. [Internett]. TV2 website. Vis sammendrag
This interview is about the antimicrobial effect of copper particles in facemasks
Campaña Perilla, Ana Lucia; Joudeh, Nadeem; Høyer, Henrik; Røyne, Anja; Linke, Dirk & Mikheenko, Pavlo (2020). Probing van der Waals and magnetic forces in bacteria with magnetic nanoparticles.
Claxton, James; Joudeh, Nadeem; Røyne, Anja; Linke, Dirk & Mikheenko, Pavlo (2020). Sequential magnetic mapping of bacteria loaded with Pd-Fe nanoparticles .
Linke, Dirk (2020). Palladium nanoparticles made by bacteria.
Linke, Dirk (2020). Biofilm-forming adhesins of the fish pathogen Yersinia ruckeri.
Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2020). Analysing the fibronectin binding properties of Bartonella henselae adhesin A.
Ryoo, David; Orwick-Rydmark, Marcella; Pang, Y; Lundqvist, Daniel; Linke, Dirk & Gumbart, JC (2020). Quantitative Comparisons of Competing Models of Autotransporter Passenger-Domain Secretion.
Thibau, Arno; Vaca, Diana; Linke, Dirk & Kempf, Volkhard A.J. (2019). Analysing the fibronectin binding domain of the Bartonella henselae adhesin A.
Orwick-Rydmark, Marcella & Linke, Dirk (2019). A novel antibiotic idea: Preventing bacterial stickiness. [Internett]. international.
Meuskens, Ina; Higson, Seamus & Linke, Dirk (2019). Innovative training networks: a new way of collaboration-propped PhD training. Medical Microbiology and Immmunology. ISSN 0300-8584. 209, s. 215–216. doi: 10.1007/s00430-019-00647-0.
Linke, Dirk (2019). The Gram-Negative Bacterial Cell Surface: How to Study Its Protein Components and How to Remove Endotoxin.
Mikheenko, Pavlo; Mikheenko, Iryna; Joudeh, Nadeem; Claxton, J. B.; Røyne, Anja & Linke, Dirk (2019). Imaging magnetism of biologically produced palladium nanoparticles .
Linke, Dirk & Joudeh, Nadeem (2019). Centre for Digital Life helps researchers right out of the gate (Senter for digitalt liv hjelper forskere ut av innovasjonsstartgropa). [Internett]. Center For Digital Life - Website.
Tietgen, M; Weidensdorfer, M; Leukert, L; Djahanshiri, Bardya; Iruegas, R & Ebersberger, Ingo [Vis alle 9 forfattere av denne artikkelen] (2019). Virulence of Acinetobacter baumannii depends on the Acinetobacter trimeric autotransporter adhesin (Ata).
Orwick-Rydmark, Marcella; Lindemann, Florian; Chauhan, Nandini; Yarava, J; Oschkinat, Hartmut & Van Rossum, Barth-J [Vis alle 7 forfattere av denne artikkelen] (2019). In situ structural and dynamic analysis of a membrane protein.
Linke, Dirk (2019). Type V secretion: membrane transport and anchoring of bacterial adhesins.
Joudeh, Nadeem & Linke, Dirk (2019). Bio-engineered Palladium Nanoparticles.
Joudeh, Nadeem & Linke, Dirk (2019). Bio-engineered Pd Nanoparticles.
Joudeh, Nadeem; Røyne, Anja; Mikheenko, Pavlo & Linke, Dirk (2019). Bio-Engineered Palladium Nanoparticles (BEDPAN).
Chowdhury, Sounak; Happonen, Lotta Johanna; Linke, Dirk & Malmström, Johan (2019). QUANTITATIVE AFFINITY-PURIFICATION AND SURFACE-ADSORPTION MASS SPECTROMETRY TO MAP STREPTOCOCCUS PYOGENES AND HUMAN PROTEIN INTERACTION.
Thibau, Arno; Vaca, Diana; Linke, Dirk; Ballhorn, Wibke & Kempf, Volkhard A.J. (2019). Analysing the Fibronectin Binding Domain of the Bartonella henselae Adhesin A.
Meuskens, Ina; Leva, Juan; Millner, Paul & Linke, Dirk (2019). Differential Adhesion of Trimeric Autotransporter Adhesins to Extracellular Matrix Proteins.
Leva, Juan; Meuskens, Ina; Gibson, Timothy M.; Linke, Dirk & Millner, Paul (2019). Biosensors for pathogen detection.
Saragliadis, Athanasios & Linke, Dirk (2019). Assay development for the discovery of small-molecule inhibitors of YadA adhesion to collagen.
Linke, Dirk (2019). Autotransporter Adhesins in the fish pathogen Yersinia ruckeri.
Røsjø, Bjarne; Orwick-Rydmark, Marcella; Linke, Dirk; Leo, Jack Christopher & Hatlem, Daniel (2019). Ny antibiotika-idé: Vil hindre bakteriene i å feste seg. [Internett]. TITAN.NO.
Linke, Dirk (2019). Insights into the autotransport process of a trimeric autotransporter, YadA.
Saragliadis, Athanasios & Linke, Dirk (2019). Screening for small-molecule inhibitors of YadA adhesion to collagen.
Orwick-Rydmark, Marcella; Van Rossum, Barth-J; Oschkinat, Hartmut & Linke, Dirk (2019). Towards the in situ structure of the Yersinia Adhesin A membrane anchor domain.
Meuskens, Ina & Linke, Dirk (2019). Binding of Yersinia Ahesin A to ECM molecules: a biosensor approach.
Hatlem, Daniel; Chauhan, Nandini; Orwick-Rydmark, Marcella; Schneider, Kenneth; Flötenmeyer, Matthias & Van Rossum, Barth-J [Vis alle 8 forfattere av denne artikkelen] (2019). Insights into the autotransport of a trimeric autotransporter.
Orwick-Rydmark, Marcella; Chauhan, Nandini; Van Rossum, Barth-J & Linke, Dirk (2019). Towards the structure of the YadA anchor domain in the native membrane.
Linke, Dirk & Saragliadis, Athanasios (2019). Bacterial adhesion to living and non-living surfaces.
Kandanur, Sai Priya Sarma; Linke, Dirk & Leo, Jack Christopher (2019). Hairpin Formation and Passenger Secretion in the Inverse Autotransporter Intimin.
Spence, Maria Helle; Linke, Dirk & Saragliadis, Athanasios (2022). Yersinia adhesins: Investigating the role of autotransporter adhesins in fish infection by Yersinia ruckeri. Universitetet i Oslo.
Hermansen, Simen; Linke, Dirk & Orwick-Rydmark, Marcella (2021). Investigating the effects of loop modifications on the folding of outer membrane protein X. Universitetet i Oslo.
Trunk, Thomas; Leo, Jack Christopher & Linke, Dirk (2020). Characterization and comparative analyses of type Vd-secreted phospholipases expressed in pathogenic bacteria. Universitetet i Oslo.
Wrobel, Agnieszka & Linke, Dirk (2019). Structural and functional studies of the Yersinia ruckeri inverse autotransporters. Universitetet i Oslo.

Se alle arbeider i Cristin

Publisert 16. okt. 2013 09:29 - Sist endret 29. jan. 2015 11:53

Prosjekter

LagLivLab

Forskergrupper

Centre for Integrative Microbial Evolution (CIME)