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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Prydz, Kristian & Shapaval, Volha
[Show all 7 contributors for this article]
(2023).
Assessment of genetically modified maize Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA-GMO-DE-2018-149).
VKM Report.
ISSN 2535-4019.
2023:21,
p. 1–14.
Full text in Research Archive
Show summary
Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 was produced by conventional breeding of the GM maize events Bt11, MIR162, MIR604, MON 89034, 5307 and GA21. Accordingly, Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 maize produces the transgenic proteins in the individual GM maize events (Cry1Ab, PAT, Vip3Aa20, PMI, mCry3A, MIR604 PMI, Cry1A.105, Cry2Ab2, eCry3.1Ab and mEPSPS). Event Bt11 maize expresses the insecticidal protein Cry1Ab that protects against feeding damage caused by certain lepidopteran pests and the phosphinothricin acetyltransferase (PAT) protein for weed control by providing tolerance to herbicide products containing glufosinate ammonium.
Event MIR162 maize expresses the insecticidal protein Vip3Aa20 that protects against feeding damage caused by certain lepidopteran pests and the PMI protein which enables transformed plant cells to utilise mannose as a primary carbon source and therefore used as a selectable marker in the development of the MIR162 maize. Event MIR604 maize expresses the insecticidal protein mCry3A that protects against feeding damage caused by certain coleopteran pests and the MIR604 PMI protein which enables transformed plant cells to utilise mannose as a primary carbon source and therefore used as a selectable marker in the development of the MIR604 maize. Event MON 89034 maize expresses the insecticidal proteins Cry1A.105 and Cry2Ab2 that protect against feeding damage caused by certain lepidopteran pests. Event 5307 maize expresses the insecticidal protein eCry3.1Ab that protects against feeding damage caused by certain coleopteran pests and the PMI protein which enables transformed plant cells to utilise mannose as a primary carbon source and therefore used as a selectable
marker in the development of the 5307 maize. Event GA21 expresses the double-mutated 5-enolpyruvylshikimate-3-phosphate synthase enzyme (mEPSPS) for weed control by providing tolerance to herbicide products containing
glyphosate.The scientific documentation provided in the application for genetically modified maize Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 is adequate for risk assessment, and in accordance with EFSA guidance on risk assessment of genetically modified plants for use in food or feed. The VKM GMO panel does not consider the introduced modifications in maize Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 to imply potential specific health or
environmental risks in Norway, compared to EU-countries The EFSA opinion is adequate also for Norwegian considerations. Therefore, a full risk assessment of maize Bt11 x MIR162 x MIR604 x MON 89034 x 5307 x GA21 was not performed by the VKM GMO Panel.
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Meuskens, Ina; Kristiansen, Per Eugen; Bardiaux, Benjamin; Koynarev, Vladimir Rosenov; Hatlem, Daniel & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Strain variations in a bacterial adhesin lead to different binding partners in the pathogen Yersinia enterocolitica
.
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified maize MON 87419 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2017-140).
VKM Report.
ISSN 2535-4019.
15,
p. 1–14.
Full text in Research Archive
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified maize GA21 x T25 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2016-137).
VKM Report.
ISSN 2535-4019.
14,
p. 1–14.
Full text in Research Archive
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified maize MON 95379 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2020‐170).
VKM Report.
ISSN 2535-4019.
12,
p. 1–14.
Full text in Research Archive
Show summary
Event MON 95379 is a genetically modified maize developed by a two-step process. In the first step, immature embryos of maize inbred line LH244 were co-cultured with a disarmed Agrobacterium tumefaciens (also known as Rhizobium radiobacter) strain ABI containing the vector PV-ZMIR522223. In the second step, selected R2 lines were crossed with maize inbred LH244 line expressing Crerecombinase, which had been transformed with vector PVZMOO513642. In the resulting plants, the CP4 EPSPS-cassette (used for selection of transformed plants) was excised by the Cre recombinase, and the Cre gene was subsequently segregated away, through conventional breeding, to obtain maize MON 95379.
Maize MON 95379 expresses Cry1B.868, a chimeric protein containing domains from Cry1A, Cry1B and Cry1C naturally expressed in Bacillus thuringiensis, and Cry1Da_7, an optimised version of Cry1Da carrying four amino acids substitutions to increase its activity.
The two Cry proteins expressed in maize MON 95379 provide protection against targeted pests within the order of butterflies and moths (Lepidoptera) including fall armyworm (Spodoptera frugiperda), sugarcane borer (Diatraea saccharalis) and corn earworm (Helicoverpa zea).
The scientific documentation provided in the application for genetically modified maize MON 95379 is adequate for risk assessment, and in accordance with EFSA guidance on risk assessment of genetically modified plants for use in food or feed. The VKM GMO panel does not consider the introduced modifications in event MON 95379 to imply potential specific health or environmental risks in Norway, compared to EU-countries. The EFSA opinion is adequate also for Norwegian considerations. Therefore, a full risk assessment of event MON 95379 was not performed by the VKM GMO Panel.
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified soybean 40‐3‐2 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (renewal application EFSA-GMO-RX-023).
VKM Report.
ISSN 2535-4019.
11,
p. 1–14.
Full text in Research Archive
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified soybean MON 87701 × MON 89788 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (renewal application EFSAGMO-RX-022).
VKM Report.
ISSN 2535-4019.
10,
p. 1–14.
Full text in Research Archive
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified soybean MON 87701 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (renewal application EFSA-GMO-RX-021).
VKM Report.
ISSN 2535-4019.
9,
p. 1–14.
Full text in Research Archive
Show summary
Event MON 87701 is a genetically modified soybean developed via Agrobacterium
tumefaciens transformation. MON 87701 plants contain the transgene cry1Ac which encodes the protein Cry1Ac. The protein Cry1Ac provides resistance against specific lepidopteran pests.
The scientific documentation provided in the renewal application (EFSA-GMO-RX-021) for soybean MON 87701 is adequate for risk assessment, and in accordance with EFSA guidance on risk assessment of genetically modified plants for use in food or feed. The VKM GMO panel does not consider the introduced modifications in soybean MON 87701 to imply potential specific health or environmental risks in Norway, compared to EU-countries. The EFSA opinion is adequate also for Norwegian considerations. Therefore, a full risk assessment of event MON 87701 was not performed by the VKM GMO Panel.
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified cotton 281‐24‐236 × 3006‐210‐23 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA-GMORX-019).
VKM Report.
ISSN 2535-4019.
02,
p. 1–14.
Full text in Research Archive
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified maize DP41143 x MON890343 x MON 874113 x DAS40278-9 and sub-combinations for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA GMO-NL-2020-171).
VKM Report.
ISSN 2535-4019.
01,
p. 1–16.
Full text in Research Archive
Show summary
Genetically modified maize DP41149 x MON 890349 x MON 874119 x DAS-40278-9 was developed by crossing to combine four single events: DP4114, MON 89034, MON 87411 and DAS-40278-9.
DP4114 express the Cry1F protein to confer protection against certain lepidopteran pests, the Cry34Ab1 and Cry35Ab1 proteins to confer protection against certain coleopteran pests and PAT protein to confer tolerance to glufosinate-ammonium-containing herbicides. MON 89034 express the Cry1A.105 and Cry2Ab2 proteins to confer protection against certain lepidopteran pests. MON 87411 express the Cry3Bb1 protein to confer protection against certain coleopteran larvae and the DvSnf7 dsRNA confer protection against western corn
rootworm, and the CP4 EPSPS protein for tolerance to glyphosate containing herbicides.
DAS-40278-9 express the AAD-1 protein to catalyse the degradation of the general class ofherbicides known as aryloxyphenoxypropionates (AOPP) and to confer tolerance to 2,4- dichlorophenoxyacetic acid (2,4-D) herbicides.
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Sanden, Monica; Ager-Wick, Eirill; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes & Prydz, Kristian
[Show all 9 contributors for this article]
(2023).
Assessment of genetically modified maize MON 87429 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2019-161).
VKM Report.
ISSN 2535-4019.
3,
p. 1–14.
Full text in Research Archive
Show summary
Event MON 87429 is a genetically modified maize developed via Agrobacterium tumefaciens transformation. MON 87429 plants contain the transgenes pat, dmo, ft_t and cp4 epsps. Maize MON 87429 encodes the DMO, PAT and FT_T proteins. In addition, maize MON 87429 encodes the CP4 EPSPS protein and utilises an endogenous maize RNAi regulatory element to suppress its expression in pollen. This results in a lack of viable pollen and thus male sterility when MON 87429 plants are exposed to glyphosate-containing herbicides at growth stages ranging from V8 to V13. This is part of a hybridisation system to be used in inbred lines to facilitate the hybrid seeds production. This is not considered an agronomic trait since the application of glyphosate outside the specific growth stages does not lead to male sterile plants but reduces plant yield compared to plants not expressing the same trait. The scientific documentation provided in the application for genetically modified maize MON 87429 is adequate for risk assessment, and in accordance with EFSA guidance on risk assessment of genetically modified plants for use in food or feed. The VKM GMO panel does
not consider the introduced modifications in event MON 87429 to imply potential specific health or environmental risks in Norway, compared to EU-countries. The EFSA opinion is adequate also for Norwegian considerations. Therefore, a full risk assessment of event MON87429 was not performed by the VKM GMO Panel
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Prydz, Kristian
(2022).
The 2022 Nobel Prize in physiology or medicine.
NBS-nytt.
ISSN 0801-3535.
4,
p. 6–9.
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Prydz, Kristian
(2022).
Nekrolog Fredrik Størmer.
NBS-nytt.
ISSN 0801-3535.
3,
p. 17–17.
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Prydz, Kristian
(2022).
Anders Jahres (store) medisinske pris for 2022 er tildelt Harald Stenmark.
NBS-nytt.
ISSN 0801-3535.
3,
p. 12–14.
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Prydz, Kristian
(2022).
Good to be back! Successful NBS winter meeting in Tromsø.
NBS-nytt.
ISSN 0801-3535.
2,
p. 14–17.
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Iannella, Nicolangelo Libero; Prydz, Kristian; Malthe-Sørensen, Anders; Einevoll, Gaute & Fyhn, Marianne
(2020).
A framework for modelling neuronal-ECM signalling.
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Iannella, Nicolangelo Libero; Prydz, Kristian; Malthe-Sørensen, Anders; Einevoll, Gaute & Fyhn, Marianne
(2019).
A new framework for modelling neural-ECM signaling.
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Iannella, Nicolangelo Libero; Prydz, Kristian; Malthe-Sørensen, Anders; Einevoll, Gaute & Fyhn, Marianne
(2019).
A new framework for modelling neural-ECM signalling and interaction.
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Vuong, Tram Thu; Rønning, Sissel Beate; Suso, Henri-Pierre; Kenny, Enda; Schmidt, Ralf & Hart, J
[Show all 9 contributors for this article]
(2016).
Eggshell Membrane – An Equivalent of Extracellular Matrix (ECM) in Avian Egg has Modulating Wound Healing Properties.
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Heggelund, Julie Elisabeth; Prydz, Kristian & Krengel, Ute
(2014).
Cholera blood-group dependence investigated by X-ray crystallography, CaCo-2 cells and ELISA.
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Prydz, Kristian
(2013).
Nobelpris for studier av vesikkeltransport.
Tidsskrift for Den norske legeforening.
ISSN 0029-2001.
23-24(133),
p. 2466–2466.
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Prydz, Kristian
(2013).
Nobelprisen i fysiologi eller medisin 2013.
NBS-nytt.
ISSN 0801-3535.
37(4),
p. 6–7.
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Prydz, Kristian
(2013).
Studentenes innsats øker studiekvaliteten.
Aftenposten (morgenutg. : trykt utg.).
ISSN 0804-3116.
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Prydz, Kristian
(2013).
Nobelpris for celle-oppdagelser Dagsnytt atten NRK 07.10.2013.
[Radio].
Norsk rikskringkasting NRK Dagsnytt atten.
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Prydz, Kristian
(2013).
Om Nobelprisen i medisin (eller fysiologi)NRK EKKO 8.10.2013.
[Radio].
Norsk rikskringkasting (NRK) EKKO.
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Heggelund, Julie Elisabeth; Prydz, Kristian & Krengel, Ute
(2013).
Cholera toxin's blood-group dependence investigated with CaCo-2 cells and ELISA.
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Grøndahl, Frøy; Tveit, Heidi & Prydz, Kristian
(2012).
Easy HPLC-based separation and quantitation of chondroitin sulphate and hyaluronan disaccharides after chondroitinase ABC treatment.
-
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Prydz, Kristian
(2011).
Bioprospektering - nytt ord men gammel virksomhet.
Nytt fra nord.
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Prydz, Kristian
(2009).
How many ways through the Golgi maze?
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Akslen, Linn Kristin Aasen; Fagereng, Gro Live; Tveit, Heidi & Prydz, Kristian
(2009).
A direct transport route from the ER to the plasma membrane?
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Prydz, Kristian
(2008).
How many ways through the Golgi maze?
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Rehn, Tommy Aune; Borge, BA; Lunde, Per Kristian; Grøndahl, Frøy; Aronsen, Jon magnus & Sjaastad, Ivar
[Show all 11 contributors for this article]
(2008).
Temporary alterations in skeletal muscle extracellular matrix during progression of congestive heart failure in rats.
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Rehn, Tommy Aune; Borge, BA; Lunde, Per Kristian; Munkvik, Morten; Sneve, Marianne Lunde & Grøndahl, Frøy
[Show all 12 contributors for this article]
(2008).
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats.
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Prydz, Kristian
(2006).
Djupedals bevegelige mål.
Forskerforum.
ISSN 0800-1715.
38(10),
p. 32–33.
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Prydz, Kristian
(2006).
Synthesis of proteoglycans and the roads to the cell surface.
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Mantzilas, Dimitrios & Prydz, Kristian
(2004).
Fra organisme til molekyl.Multimedia.
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Grøndahl, Frøy; Elmi, Ayan & Prydz, Kristian
(2004).
Effects of Bafilomycin A1 on synthesis and sorting of proteoglycans and the glycoprotein gp80 in Madin-Darby canine kidney (MDCK) cells.
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Prydz, Kristian
(2002).
Feighet og mot blant akademikere og journalister.
Aftenposten (morgenutg. : trykt utg.).
ISSN 0804-3116.
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Prydz, Kristian
(2001).
Sugars without any GAGs?
Journal of Cell Science.
ISSN 0021-9533.
114,
p. 627–628.
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Prydz, Kristian
(2001).
Carbohydrate recognition systems.
Journal of Cell Science.
ISSN 0021-9533.
114.
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Prydz, Kristian
(2001).
Biologisk forskning i Norge som slaktoffer.
NBS-nytt.
ISSN 0801-3535.
25(1),
p. 36–38.
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Prydz, Kristian
(2001).
Hva norsk forskning kan lære - og ikke lære - av norsk idrett.
NBS-nytt.
ISSN 0801-3535.
p. 26–28.
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Borrebæk, Jørgen; Prydz, Kristian & Kolset, Svein Olav
(2001).
Effect of the AGE-product CML-BSA on proteoglycan biosynthesis in kidney epithelial cells.
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Tveit, Heidi; Vuong, Tram Thu; Grøndahl, Frøy; Kolset, Svein Olav & Prydz, Kristian
(2001).
Sorting of proteolycans in the secretory pathway of epithelial MDCK cells.
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Vuong, Tram Thu; Prydz, Kristian & Kolset, Svein Olav
(2001).
Proteoglycan expression and enzyme secretion in polarized human colon carcinoma Caco-2 cells.
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Heggelund, Julie Elisabeth; Krengel, Ute & Prydz, Kristian
(2015).
Cholera toxin – carbohydrate interaction as the basis for cholera blood-group dependence.
Akademika publishing.
ISSN 1501-7710.