Tone Fredsvik Gregers

Senior lecturer, scientific leader KURT, head of science teacher education
Norwegian version of this page
Mobile phone 99697154 99697154
Room Ø468
Username
Visiting address Sem Sælands vei 24
Postal address 0316

Academic Interests

Education, scientific teaching, dissemination, pedagogy and didactics

Immunology, cell biology, molecular biology. More specifically intracellular transport and regulation of immune molecules.

Teaching

BIOS1110 - Celle- og molekylærbiologi

BIOS1120 - Fysiologi

BIOS3700 - Cellebiologi 2

BIOS5000 - Biologididaktikk i praksis

NAT2000 - Naturfag i praksis

NAT3000 - Realfaglig programmering i skolen

MNPED9000 - Teaching in STEM

Higher education and employment history

My education is from University of Oslo, with a master in cell biology (1997) and a PhD (dr. scient.) degree in cellular immunology. I worked for three years as a post. doc. at Institute of Cancer Research, the Radium Hospital in the lab of Professor Kirsten Sandvig, and then for 2 years as a scientific assistant in the lab of Professor Oddmund Bakke at Department of Molecular Biosciences, University of Oslo. June 2008 I started a new post. doc. period, financed by the Norwegian Research Council, as a group leader. 

In parallel with the research, I have taught several courses at the institute as well as supervised both PhD and master students. From September 2013 I left research in cellular immunology and started as a senior lecturer at the School Laboratory of Biology. Here I was involved in continuing education for teachers, taught high school students practical lab skills and developed teaching plans adapted to the science standards in science and biology. Since 2015, I have expanded my expertise in pedagogy and scientific teaching and work with both teaching and education quality at the Center for Teaching and Learning in Science (KURT).

Prices

Winner of Olav Thon Foundation's national price for excellent teaching 2022

Merited teacher at UiO 2021

The lecturer of the year at the Faculty of mathematics and natural sciences 2018 

The lecturer of the year at the Department of Biosciences 2017

The dissemination price at the Department of Biosciences 2016 

The innovation price at the Department of Biosciences 2011

Textbooks for lower secondary school

Solaris 8-10 - textbooks in natural sciences for grade 8-10

Dissemination

Author of the book "Alt du må vite om vaksiner"

Folkeopplysningen NRK sesong 2

Aftenposten Viten 2015

Aftenposten Viten 2018

Publications

  • Eliassen, June Edvarda; Bøe, Maria Vetleseter; Nederbragt, Lex; Berg, Marthe Mjøen & Gregers, Tone Fredsvik (2022). Motivasjon for beregningsorientert biologi og sammenhengen med matematikk R2 fra videregående opplæring. Nordic Journal of STEM Education. ISSN 2535-4574. 4(2), p. 58–70. doi: 10.5324/njsteme.v4i2.4026. Full text in Research Archive
  • Gregers, Tone Fredsvik & Lunde, Mai Lill Suhr (2021). Students' understanding of the cell and cellular structures. Nordic Studies in Science Education. ISSN 1504-4556. 17(2), p. 225–241. doi: 10.5617/NORDINA.7306. Full text in Research Archive
  • Sjøberg, Mari; Gregers, Tone Fredsvik; Ødegaard, Marianne & Tsigaridas, Kristin Glørstad (2020). Biologilæreres kryssing av kulturgrenser - fra en naturvitenskapelig kultur til en skolekultur. Nordic Studies in Science Education. ISSN 1504-4556. 16(1), p. 52–66. doi: 10.5617/NORDINA.6518. Full text in Research Archive
  • Solbakken, Monica Hongrø; Jentoft, Sissel; Reitan, Trond; Mikkelsen, Helene; Gregers, Tone Fredsvik & Bakke, Oddmund [Show all 8 contributors for this article] (2019). Disentangling the immune response and host-pathogen interactions in Francisella noatunensis infected Atlantic cod. Comparative Biochemistry and Physiology - Part D:Genomics and Proteomics. ISSN 1744-117X. 30, p. 333–346. doi: 10.1016/j.cbd.2019.04.004. Full text in Research Archive
  • Niazy, Naima; Temme, Sebastian; Bocuk, Derya; Giesen, Carmen; Konig, Angelika & Temme, Nadine [Show all 12 contributors for this article] (2017). Misdirection of endosomal trafficking mediated by herpes simplex virus-encoded glycoprotein B. The FASEB Journal. ISSN 0892-6638. 31(4), p. 1650–1667. doi: 10.1096/fj.201600521R.
  • Solbakken, Monica Hongrø; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Seppola, Marit; Gregers, Tone Fredsvik & Jakobsen, Kjetill Sigurd [Show all 7 contributors for this article] (2016). Evolutionary redesign of the Atlantic cod (Gadus morhua L.) Toll-like receptor repertoire by gene losses and expansions. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep25211. Full text in Research Archive
  • Sand, Kine Marita Knudsen; Landsverk, Ole J. B.; Berg-Larsen, Axel; Bakke, Oddmund & Gregers, Tone Fredsvik (2014). The human-specific invariant chain isoform Iip35 modulates Iip33 trafficking and function. Immunology and Cell Biology. ISSN 0818-9641. 92(9), p. 791–798. doi: 10.1038/icb.2014.54.
  • Waelchli, Sebastien; Kumari, Shraddha; Fallang, Lars-Egil; Sand, Kine Marita Knudsen; Yang, Weiwen & Landsverk, Ole J. B. [Show all 9 contributors for this article] (2014). Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. European Journal of Immunology. ISSN 0014-2980. 44(3), p. 774–784. doi: 10.1002/eji.201343671.
  • Berg-Larsen, Axel; Landsverk, Ole J. B.; Progida, Cinzia ; Gregers, Tone Fredsvik & Bakke, Oddmund (2013). Differential Regulation of Rab GTPase Expression in Monocyte-Derived Dendritic Cells upon Lipopolysaccharide Activation: A Correlation to Maturation-Dependent Functional Properties. PLOS ONE. ISSN 1932-6203. 8(9). doi: 10.1371/journal.pone.0073538.
  • Malmstrøm, Martin; Jentoft, Sissel; Gregers, Tone Fredsvik & Jakobsen, Kjetill Sigurd (2013). Unraveling the Evolution of the Atlantic Cod’s (Gadus morhua L.) Alternative Immune Strategy. PLOS ONE. ISSN 1932-6203. 8(9). doi: 10.1371/journal.pone.0074004. Full text in Research Archive
  • Gregers, Tone Fredsvik; Skånland, Sigrid Strand; Waelchli, Sebastien; Bakke, Oddmund & Sandvig, Kirsten (2013). BiP Negatively Affects Ricin Transport. Toxins. ISSN 2072-6651. 5(5), p. 969–982. doi: 10.3390/toxins5050969.
  • Skjeldal, Frode Miltzow; Strunze, Sten; Bergeland, Trygve; Walseng, Even; Gregers, Tone Fredsvik & Bakke, Oddmund (2012). The fusion of early endosomes induces molecular-motor-driven tubule formation and fission. Journal of Cell Science. ISSN 0021-9533. 125(8), p. 1910–1919. doi: 10.1242/jcs.092569.
  • Landsverk, Ole J. B.; Barois, Nicolas; Gregers, Tone Fredsvik & Bakke, Oddmund (2011). Invariant chain increases the half-life of MHC II by delaying endosomal maturation. Immunology and Cell Biology. ISSN 0818-9641. 89(5), p. 619–629. doi: 10.1038/icb.2010.143.
  • Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin & Gregers, Tone Fredsvik [Show all 42 contributors for this article] (2011). The genome sequence of Atlantic cod reveals a unique immune system. Nature. ISSN 0028-0836. 477(7363), p. 207–210. doi: 10.1038/nature10342. Full text in Research Archive
  • Landsverk, OJB; Bakke, Oddmund & Gregers, TF (2009). MHC II and the Endocytic Pathway: Regulation by Invariant Chain. Scandinavian Journal of Immunology. ISSN 0300-9475. 70(3), p. 184–193. doi: 10.1111/j.1365-3083.2009.02301.x.
  • Walchli, S; Skånland, Sigrid Strand; Gregers, Tone Fredsvik; Lauvrak, Silje Anett Ugland; Torgersen, Maria Lyngaas & Ying, M [Show all 9 contributors for this article] (2008). The mitogen-activated protein kinase p38 links Shiga toxin-dependent signaling and trafficking. Molecular Biology of the Cell. ISSN 1059-1524. 19(1), p. 95–104. doi: 10.1091/mbc.E07-06-0565.
  • Slominska-Wojewodzka, M; Gregers, Tone Fredsvik; Waelchli, Sebastien & Sandvig, Kirsten (2006). EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol. Molecular Biology of the Cell. ISSN 1059-1524. 17, p. 1664–1675.
  • Michaelsen, Terje Einar; Thommesen, John E.; Ihle, Øistein; Gregers, Tone F.; Sandin, Randi Helene & Brekke, Ole Henrik [Show all 7 contributors for this article] (2006). A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells. European Journal of Immunology. ISSN 0014-2980. 36(1), p. 129–138. doi: 10.1002/eji.200535178. Full text in Research Archive

View all works in Cristin

  • Eliassen, June Edvarda; Bøe, Maria Vetleseter; Nederbragt, Lex & Gregers, Tone Fredsvik (2021). Motivasjon for beregningsorientert biologi og sammenhengen med matematikk R2 fra videregående opplæring.
  • Erlien, Wenche; Sørborg, Øystein; Gregers, Tone Fredsvik; Haug, Berit S & Korsager, Majken (2021). Virus og vaksine.
  • Tellefsen, Cathrine Wahlstrøm; Tsigaridas, Kristin Glørstad & Gregers, Tone Fredsvik (2018). Science teacher education as an asset and an opportunity for educational development in STEM disciplinary departments.
  • Gregers, Tone Fredsvik (2015). Slik fungerer vaksinene i barnevaksinasjonsprogrammet. Aftenposten Viten. ISSN 2464-3033.
  • Gregers, Tone Fredsvik & Sørbye, Sveinung Wergeland (2014). Derfor blir menn sykere av influensa. [Internet]. ABC nyheter.
  • Wälchli, Sebastien; Landsverk, Ole J. B.; Fallang, Lars-Egil; Olweus, Johanna; Bakke, Oddmund & Gregers, Tone Fredsvik (2012). Invariant chain as a tool to load antigenic peptides on MHC class I. Molecular Immunology. ISSN 0161-5890. 51(1), p. 16–16. doi: 10.1016/j.molimm.2012.02.039.
  • Sand, Kine Marita Knudsen; Landsverk, Ole J. B.; Bakke, Oddmund & Gregers, Tone Fredsvik (2012). Intracellular trafficking of the human invariant chain isoforms, Iip33 and Iip35. Molecular Immunology. ISSN 0161-5890. 51(1), p. 30–30. doi: 10.1016/j.molimm.2012.02.081.
  • Berg-Larsen, Axel; Landsverk, Ole J. B.; Gregers, Tone Fredsvik & Bakke, Oddmund (2012). Rab GTPases are differentially regulated during DC maturation. Molecular Immunology. ISSN 0161-5890. 51(1), p. 8–8. doi: 10.1016/j.molimm.2012.02.016.
  • Kucera, Ana; Bakke, Oddmund & Gregers, Tone Fredsvik (2012). Direct targeting of invariant chain to the MHC II loading compartment. Molecular Immunology. ISSN 0161-5890. 51(1), p. 20–21. doi: 10.1016/j.molimm.2012.02.054.
  • Landsverk, Ole J. B.; Gregers, Tone Fredsvik & Bakke, Oddmund (2012). Differential regulation of MHC II and invariant chain expression during maturation of monocyte derived dendritic cells and how invariant chain increases the half-life of MHC II by delaying endosomal maturation. Molecular Immunology. ISSN 0161-5890. 51(1), p. 7–7. doi: 10.1016/j.molimm.2012.02.012.
  • Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin & Gregers, Tone Fredsvik [Show all 18 contributors for this article] (2011). The genome of Atlantic cod reveals a unique immune system.
  • Kucera, Ana; Bakke, Oddmund & Gregers, Tone Fredsvik (2011). Direct Targeting of Invariant Chain to the MHC II Loading Compartment. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 362–362.
  • Berg-Larsen, Axel; Landsverk, Ole J. B.; Gregers, Tone Fredsvik & Bakke, Oddmund (2011). Rab GTPases are Differentially Regulated Duringe DC Maturation. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 361–361.
  • Sand, Kine Marita Knudsen; Bakke, Oddmund & Gregers, Tone Fredsvik (2011). The Role of li p35 in MHC Class II Antigen Presentation. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 358–358.
  • Kucera, Ana; Bakke, Oddmund & Gregers, Tone Fredsvik (2011). The Role of Inhibitory NKR-P1 Receptors in the Gut. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 362–363.

View all works in Cristin

Published Nov. 4, 2010 2:38 PM - Last modified Aug. 2, 2022 11:20 PM