Kirsten Sandvig

Professor emerita - Institutt for biovitenskap
Image of Kirsten Sandvig
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Visiting address Sem Sælands vei 24
Postal address Postboks 1032 Blindern

Academic Interests

Intracellular transport of endocytosed ligands, endocytic mechanisms, transport of protein toxins from plants and bacteria. Toxins are used as probes to characterize intracellular transport and they are studied since they can be used in diagnosis and therapy of cancer. For more information, please see my home-page at Oslo University Hospital: http://www.ous-research.no/sandvig/

Teaching

MBV4240/MBV9240 - BIochemical mechanisms in intracellular transport

 

Publications

  • Hessvik, Nina Pettersen; Sagini, Krizia; Romero, Silvana Angelica Troncoso; Ramirez, Manuel; Rodriguez, Marta & Tutturen, Astrid Elisabeth Voorham [Show all 11 contributors for this article] (2023). siRNA screening reveals that SNAP29 contributes to exosome release. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 80. doi: 10.1007/s00018-023-04822-8. Full text in Research Archive
  • Skotland, Tore; Llorente, Alicia & Sandvig, Kirsten (2023). Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function? Cold Spring Harbor Perspectives in Biology. ISSN 1943-0264. 15(8), p. 1–18. doi: 10.1101/cshperspect.a041415.
  • Bousquet, Paula; Manna, Dipankar; Sandvik, Joe Alexander; Arntzen, Magnus Øverlie; Moreno, Ernesto & Sandvig, Kirsten [Show all 7 contributors for this article] (2022). SILAC-based quantitative proteomics and microscopy analysis of cancer cells treated with the N-glycolyl GM3-specific anti-tumor antibody 14F7. Frontiers in Immunology. ISSN 1664-3224. 13. doi: 10.3389/fimmu.2022.994790. Full text in Research Archive
  • Skotland, Tore; Iversen, Tore Geir; Llorente, Alicia & Sandvig, Kirsten (2022). Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges. Advanced Drug Delivery Reviews. ISSN 0169-409X. 186, p. 1–17. doi: 10.1016/j.addr.2022.114326. Full text in Research Archive
  • Sandvig, Kirsten; Kavaliauskiene, Simona; Myrann, Anne-Grethe; Iversen, Tore Geir & Skotland, Tore (2022). Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC. Toxins. ISSN 2072-6651. 14(5), p. 1–13. doi: 10.3390/toxins14050360. Full text in Research Archive
  • Skotland, Tore & Sandvig, Kirsten (2022). Need for more focus on lipid species in studies of biological and model membranes. Progress in lipid research. ISSN 0163-7827. 86, p. 1–12. doi: 10.1016/j.plipres.2022.101160. Full text in Research Archive
  • Øverbye, Anders; Torgersen, Maria Lyngaas; Sønstevold, Tonje; Iversen, Tore Geir; Mørch, Ýrr Asbjørg & Skotland, Tore [Show all 7 contributors for this article] (2021). Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: Toxicity and changes in the proteome of breast, colon and prostate cancer cells. Nanotoxicology. ISSN 1743-5390. 15(7), p. 865–884. doi: 10.1080/17435390.2021.1924888. Full text in Research Archive
  • Rudolph, Michael J.; Poon, Amanda Y.; Kavaliauskiene, Simona; Myrann, Anne-Grethe; Reynolds-Peterson, Claire & Davis, Simon A. [Show all 9 contributors for this article] (2021). Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface. Journal of Molecular Biology (JMB). ISSN 0022-2836. 433(15), p. 1–20. doi: 10.1016/j.jmb.2021.167086.
  • Sandvig, Kirsten; Kavaliauskiene, Simona & Skotland, Tore (2021). The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport. Toxins. ISSN 2072-6651. 13(6). doi: 10.3390/toxins13060377. Full text in Research Archive
  • Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg & Snipstad, Sofie [Show all 13 contributors for this article] (2021). Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft. Nanomaterials. ISSN 2079-4991. 11(5). doi: 10.3390/nano11051140. Full text in Research Archive
  • Skotland, Tore; Iversen, Tore Geir & Sandvig, Kirsten (2021). Cellular uptake of nanoparticles: Involvement of caveolae? Precision Nanomedicine (PRNANO). ISSN 2639-9431. 4(2), p. 782–786. doi: 10.33218/001c.22201. Full text in Research Archive
  • Valsalakumari, Remya; Yadava, Sunil Kumar; Szwed, Marzena; Pandya, Abhilash D.; Mælandsmo, Gunhild Mari & Torgersen, Maria Lyngaas [Show all 10 contributors for this article] (2021). Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells. . International Journal of Pharmaceutics. ISSN 0378-5173. 597(120217). doi: 10.1016/j.ijpharm.2021.120217. Full text in Research Archive
  • Skotland, Tore & Sandvig, Kirsten (2021). Transport of nanoparticles across the endothelial cell layer. Nano Today. ISSN 1748-0132. 36. doi: 10.1016/j.nantod.2020.101029. Full text in Research Archive
  • Tsjokajev, Ahmad; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Anne Berit Dyve, Lingelem; Skotland, Tore & Sandvig, Kirsten [Show all 7 contributors for this article] (2020). Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase. Journal of chromatography. B. ISSN 1570-0232. 1160, p. 1–6. doi: 10.1016/j.jchromb.2020.122384. Full text in Research Archive
  • Sønstevold, Tonje; Engedal, Nikolai; Mørch, Ýrr Asbjørg; Iversen, Tore Geir; Skotland, Tore & Sandvig, Kirsten [Show all 7 contributors for this article] (2020). Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation. Journal of Biomedical Nanotechnology. ISSN 1550-7033. 16(4), p. 432–445. doi: 10.1166/jbn.2020.2906. Full text in Research Archive
  • Torgersen, Maria Lyngaas; Judge, Peter J.; Bada Juarez, Juan F.; Pandya, Abhilash D.; Fusser, Markus & Davies, Charlie W. [Show all 12 contributors for this article] (2020). Physicochemical characterization, toxicity and in vivo biodistribution studies of a discoidal, lipid-based drug delivery vehicle: Lipodisq nanoparticles containing doxorubicin. Journal of Biomedical Nanotechnology. ISSN 1550-7033. 16(4), p. 419–431. doi: 10.1166/jbn.2020.2911. Full text in Research Archive
  • Lingelem, Anne Berit Dyve; Kavaliauskiene, Simona; Halsne, Ruth; Klokk, Tove Irene; Surma, Michal A. & Klose, Christian [Show all 8 contributors for this article] (2020). Diacylglycerol Kinase and Phospholipase D Inhibitors Alter the Cellular Lipidome and Endosomal Sorting Towards the Golgi Apparatus. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. doi: 10.1007/s00018-020-03551-6. Full text in Research Archive
  • Skotland, Tore; Sagini, Krizia; Sandvig, Kirsten & Llorente, Alicia (2020). An emerging focus on lipids in extracellular vesicles. Advanced Drug Delivery Reviews. ISSN 0169-409X. 159, p. 308–321. doi: 10.1016/j.addr.2020.03.002. Full text in Research Archive
  • Skotland, Tore; Kavaliauskiene, Simona & Sandvig, Kirsten (2020). The role of lipid species in membranes and cancer-related changes. Cancer Metastasis Review. ISSN 0167-7659. 39, p. 343–360. doi: 10.1007/s10555-020-09872-z. Full text in Research Archive
  • Pandya, Abhilash D.; Øverbye, Anders; Saharia, Priyanka; Gaware, Vivek S.; Høgset, Håkon & Masson, Már [Show all 11 contributors for this article] (2020). Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer. Biomacromolecules. ISSN 1525-7797. 21, p. 1489–1498. doi: 10.1021/acs.biomac.0c00061. Full text in Research Archive
  • Szwed, Marzena; Torgersen, Maria Lyngaas; Kumari, Remya Valsala; Yadava, Sunil Kumar; Pust, Sascha & Iversen, Tore Geir [Show all 9 contributors for this article] (2020). Biological response and cytotoxicity induced by lipid nanocapsules . Journal of Nanobiotechnology. ISSN 1477-3155. 18(5). doi: 10.1186/s12951-019-0567-y. Full text in Research Archive
  • Pandya, Abhilash D.; Jäger, Eliézer; Fam, Shahla Bagheri; Höcherl, Anita; Jäger, Alessandro & Sincari, Vladimir [Show all 12 contributors for this article] (2019). Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy. International Journal of Nanomedicine. ISSN 1176-9114. 14, p. 6269–6285. doi: 10.2147/IJN.S208938. Full text in Research Archive
  • Skotland, Tore & Sandvig, Kirsten (2019). The role of PS 18:0/18:1 in membrane function. Nature Communications. ISSN 2041-1723. 10(1), p. 1–10. doi: 10.1038/s41467-019-10711-1. Full text in Research Archive
  • Sowa-Rogozińska, Natalia; Sominska, Hanna; Nowakowska-Gołacka, Jowita; Sandvig, Kirsten & Słomińska-Wojewódzka, Monika (2019). Intracellular transport and cytotoxicity of the protein toxin ricin. Toxins. ISSN 2072-6651. 11:350(6), p. 1–37. doi: 10.3390/toxins11060350. Full text in Research Archive
  • Szwed, Marzena; Sønstevold, Tonje; Øverbye, Anders; Engedal, Nikolai; Grallert, Beata & Mørch, Ýrr Asbjørg [Show all 11 contributors for this article] (2019). Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death. Nanotoxicology. ISSN 1743-5390. 13(6), p. 761–782. doi: 10.1080/17435390.2019.1576238. Full text in Research Archive
  • Skotland, Tore; Hessvik, Nina Pettersen; Sandvig, Kirsten & Llorente Martinez, Alicia (2019). Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology. Journal of Lipid Research. ISSN 0022-2275. 60, p. 9–18. doi: 10.1194/jlr.R084343. Full text in Research Archive
  • Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F. & Kildal, Wanja [Show all 16 contributors for this article] (2018). Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft. Journal of Controlled Release. ISSN 0168-3659. 293, p. 183–192. doi: 10.1016/j.jconrel.2018.11.029. Full text in Research Archive
  • Sandvig, Kirsten; Kavaliauskiene, Simona & Skotland, Tore (2018). Clathrin-independent endocytosis: an increasing degree of complexity. Histochemistry and Cell Biology. ISSN 0948-6143. 150, p. 107–118. doi: 10.1007/s00418-018-1678-5. Full text in Research Archive
  • Sulheim, Einar; Iversen, Tore Geir; To, Vu; Klinkenberg, Geir; Sletta, Håvard & Schmid, Ruth [Show all 12 contributors for this article] (2017). Cytotoxicity of poly(Alkyl cyanoacrylate) nanoparticles. International Journal of Molecular Sciences. ISSN 1661-6596. 18(11). doi: 10.3390/ijms18112454. Full text in Research Archive
  • Taubenschmid, Jasmin; Stadlmann, Johannes; Jost, Markus; Klokk, Tove Irene; Rillahan, Cory D. & Leibbrandt, Andreas [Show all 16 contributors for this article] (2017). A vital sugar code for ricin toxicity. Cell Research. ISSN 1001-0602. 27(11), p. 1351–1364. doi: 10.1038/cr.2017.116.
  • Øverbye, Anders; Holsæter, Ann Mari; Fusser, Markus; Skalko-Basnet, Natasa; Iversen, Tore Geir & Torgersen, Maria Lyngaas [Show all 12 contributors for this article] (2017). Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide. OncoTarget. ISSN 1949-2553. 8(44), p. 76921–76934. doi: 10.18632/oncotarget.20217. Full text in Research Archive
  • Vestad, Beate; Llorente, Alicia; Neurauter, Axl; Phuyal, Santosh; Kierulf, Bente & Kierulf, Peter [Show all 10 contributors for this article] (2017). Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study. Journal of Extracellular Vesicles. ISSN 2001-3078. 6(1), p. 1–11. doi: 10.1080/20013078.2017.1344087. Full text in Research Archive
  • Simm, Roger; Kvalvaag, Audun Sverre Myrset; van Deurs, Bo; Lindback, Toril & Sandvig, Kirsten (2017). Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network. Experimental Cell Research. ISSN 0014-4827. 357(1), p. 67–78. doi: 10.1016/j.yexcr.2017.04.025.
  • Skotland, Tore; Sandvig, Kirsten & Llorente, Alicia (2017). Lipids in exosomes: Current knowledge and the way forward. Progress in lipid research. ISSN 0163-7827. 66, p. 30–41. doi: 10.1016/j.plipres.2017.03.001. Full text in Research Archive
  • Hardes, Kornelia; Ivanova, Teodora; Thaa, Bastian; McInerney, Gerald M; Klokk, Tove Irene & Sandvig, Kirsten [Show all 9 contributors for this article] (2017). Elongated and shortened peptidomimetic inhibitors of the proprotein furin. ChemMedChem. ISSN 1860-7179. 12(8), p. 613–620. doi: 10.1002/cmdc.201700108.
  • Ailte, Ieva; Anne Berit Dyve, Lingelem; Kvalvaag, Audun Sverre Myrset; Kavaliauskiene, Simona; Brech, Andreas & Koster, Gerbrand [Show all 10 contributors for this article] (2017). Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis. Traffic: The moving front of cell biology. ISSN 1398-9219. 18(3), p. 176–191. doi: 10.1111/tra.12468. Full text in Research Archive
  • Kavaliauskiene, Simona; Anne Berit Dyve, Lingelem; Skotland, Tore & Sandvig, Kirsten (2017). Protection against Shiga Toxins. Toxins. ISSN 2072-6651. 9(2). doi: 10.3390/toxins9020044. Full text in Research Archive
  • Manna, Dipankar; Pust, Sascha; Torgersen, Maria Lyngaas; Cordara, Gabriele; Kunzler, Markus & Krengel, Ute [Show all 7 contributors for this article] (2017). Polyporus squamosus lectin 1a (PSL1a) exhibits cytotoxicity in mammalian cells by disruption of focal adhesions, inhibition of protein synthesis and induction of apoptosis. PLOS ONE. ISSN 1932-6203. 12(1). doi: 10.1371/journal.pone.0170716. Full text in Research Archive
  • Skotland, Tore; Ekroos, Kim; Kauhanen, Dimple; Simolin, Helena; Seierstad, Therese & Berge, Viktor [Show all 8 contributors for this article] (2017). Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers. European Journal of Cancer. ISSN 0959-8049. 70, p. 122–132. doi: 10.1016/j.ejca.2016.10.011.
  • Ling, Wang; Skotland, Tore; Berge, Viktor; Sandvig, Kirsten & Llorente, Alicia (2017). Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 98, p. 80–85. doi: 10.1016/j.ejps.2016.09.023.
  • Torgersen, Maria Lyngaas; Klokk, Tove Irene; Kavaliauskiene, Simona; Klose, Christian; Simons, Kai & Skotland, Tore [Show all 7 contributors for this article] (2016). The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. OncoTarget. ISSN 1949-2553. 7(52), p. 86871–86888. doi: 10.18632/oncotarget.13508.
  • Kavaliauskiene, Simona; Torgersen, Maria Lyngaas; Lingelem , Anne Berit Dyve; Klokk, Tove Irene; Lintonen, Tuulia & Simolin, Helena [Show all 9 contributors for this article] (2016). Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport. OncoTarget. ISSN 1949-2553. 7(48), p. 79885–79900. doi: 10.18632/oncotarget.13089.
  • Hessvik, Nina Pettersen; Øverbye, Anders; Brech, Andreas; Torgersen, Maria Lyngaas; Jakobsen, Ida Seim & Sandvig, Kirsten [Show all 7 contributors for this article] (2016). PIKfyve inhibition increases exosome release and induces secretory autophagy. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 73(24), p. 4717–4737. doi: 10.1007/s00018-016-2309-8.
  • Skotland, Tore; Ekroos, Kim; Kavaliauskiene, Simona; Bergan, Jonas; Kauhanen, Dimple & Lintonen, Tuulia [Show all 7 contributors for this article] (2016). Determining the turnover of glycosphingolipid species by stable-isotope tracer lipidomics. Journal of Molecular Biology (JMB). ISSN 0022-2836. 428(24), p. 4856–4866. doi: 10.1016/j.jmb.2016.06.013.
  • Hjelseth, Ieva Ailte; Lingelem , Anne Berit Dyve; Kavaliauskiene, Simona; Bergan, Jonas; Kvalvaag, Audun Sverre Myrset & Myrann, Anne-Grethe [Show all 8 contributors for this article] (2016). Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep30336.
  • Asp, Nagham Theres; Kvalvaag, Audun Sverre Myrset; Sandvig, Kirsten & Pust, Sascha (2016). Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins. OncoTarget. ISSN 1949-2553. 7(18), p. 25443–25460. doi: 10.18632/oncotarget.8327.
  • Herrera, Cristina; Klokk, Tove Irene; Cole, Richard; Sandvig, Kirsten & Mantis, Nicholas J (2016). A bispecific antibody promotes aggregation of ricin toxin on cell surfaces and alters dynamics of toxin internalization and trafficking. PLOS ONE. ISSN 1932-6203. 11:0156893(6). doi: 10.1371/journal.pone.0156893.
  • Róg, Tomasz; Orłowski, Adam; Llorente, Alicia; Skotland, Tore; Sylvänne, Tuulia & Kauhanen, Dimple [Show all 9 contributors for this article] (2016). Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters. Data in Brief. ISSN 2352-3409. 7, p. 1171–1174. doi: 10.1016/j.dib.2016.03.067.
  • Yermakova, Anastasiya; Klokk, Tove Irene; O'Hara, Joanne M.; Cole, Richard; Sandvig, Kirsten & Mantis, Nicholas J. (2016). Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep22721.
  • Klokk, Tove Irene; Kavaliauskiene, Simona & Sandvig, Kirsten (2016). Cross-linking of glycosphingolipids at the plasma membrane: Consequences for intracellular signaling and traffic. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 73(6), p. 1301–1316. doi: 10.1007/s00018-015-2049-1.
  • Rog, Tomasz; Orlowski, Adam; Llorente, Alicia; Skotland, Tore; Sylvänne, Tuulia & Kauhanen, Dimple [Show all 9 contributors for this article] (2016). Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner. Biochimica et Biophysica Acta - Biomembranes. ISSN 0005-2736. 1858(2), p. 281–288. doi: 10.1016/j.bbamem.2015.12.003.
  • Kymre, Linn Furebotten; Simm, Roger; Skotland, Tore & Sandvig, Kirsten (2015). Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells. Pathogens and Disease. ISSN 2049-632X. 73(9), p. 1–9. doi: 10.1093/femspd/ftv083.
  • Øverbye, Anders; Skotland, Tore; Koehler, Christian; Thiede, Bernd; Seierstad, Therese & Berge, Viktor [Show all 8 contributors for this article] (2015). Identification of prostate cancer biomarkers in urinary exosomes. OncoTarget. ISSN 1949-2553. 6(30), p. 30357–30376. doi: 10.18632/oncotarget.4851.
  • Kavaliauskiene, Simona; Skotland, Tore; Sylvänne, Tuulia; Simolin, Helena; Klokk, Tove Irene & Torgersen, Maria Lyngaas [Show all 10 contributors for this article] (2015). Novel actions of 2-deoxy-D-glucose: Protection against Shiga toxins and changes in cellular lipids. Biochemical Journal. ISSN 0264-6021. 470, p. 23–37. doi: 10.1042/BJ20141562.
  • Skotland, Tore; Iversen, Tore Geir; Torgersen, Maria Lyngaas & Sandvig, Kirsten (2015). Cell-penetrating peptides: Possibilities and challenges for drug delivery in vitro and in vivo. Molecules. ISSN 1431-5157. 20(7), p. 13313–13323. doi: 10.3390/molecules200713313.
  • Sandvig, Kirsten; Lingelem, Anne Berit Dyve; Skotland, Tore & Bergan, Jonas (2015). Shiga toxins: Properties and action on cells. In Alouf, Joseph E; Ladant, Daniel & Popoff, Michel R (Ed.), The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition. Elsevier. ISSN 978-0-12-800188-2. p. 267–286.
  • Slominska-Wojewodzka, Monika & Sandvig, Kirsten (2015). The role of lectin-carbohydrate interactions in the regulation of ER-associated protein degradation. Molecules. ISSN 1431-5157. 20(6), p. 9816–9846. doi: 10.3390/molecules20069816.
  • Lingelem, Anne Berit Dyve; Hjelseth, Ieva Ailte; Simm, Roger; Torgersen, Maria Lyngaas & Sandvig, Kirsten (2015). Geldanamycin enhances retrograde transport of Shiga toxin in HEp-2 cells. PLOS ONE. ISSN 1932-6203. 10:e0129214(5). doi: 10.1371/journal.pone.0129214.
  • Hardes, Kornelia; Becker, Gero L.; Lu, Yinghui; Dahms, Sven O.; Köhler, Susanne & Beyer, Wolfgang [Show all 14 contributors for this article] (2015). Novel furin inhibitors with potent anti-infectious activity. ChemMedChem. ISSN 1860-7179. 10(7), p. 1218–1231. doi: 10.1002/cmdc.201500103.
  • Phuyal, Santosh; Skotland, Tore; Hessvik, Nina Pettersen; Simolin, Helena; Øverbye, Anders & Brech, Andreas [Show all 10 contributors for this article] (2015). The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells. Journal of Biological Chemistry. ISSN 0021-9258. 290, p. 4225–4237. doi: 10.1074/jbc.M114.593962.
  • Sokołowska, Iwona; Piłka, Ewa S.; Sandvig, Kirsten; Węgrzyn, Grzegorz & Słomińska-Wojewódzka, Monika (2015). Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells. BMC Cell Biology. ISSN 1471-2121. 16(1). doi: 10.1186/s12860-015-0047-7.
  • Holland, Petter; Torgersen, Maria Lyngaas; Sandvig, Kirsten & Simonsen, Anne (2014). LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis. Traffic: The moving front of cell biology. ISSN 1398-9219. 15(12), p. 1390–1405. doi: 10.1111/tra.12227.
  • Bergan, Jonas; Skotland, Tore; Anne Berit Dyve, Lingelem; Simm, Roger; Spilsberg, Bjørn & Lindback, Toril [Show all 10 contributors for this article] (2014). The ether lipid precursor hexadecylglycerol protects against Shiga toxins. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 71, p. 4285–4300. doi: 10.1007/s00018-014-1624-1.
  • Cordara, Gabriele; Winter, Harry C.; Goldstein, Irwin J.; Krengel, Ute & Sandvig, Kirsten (2014). The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 447(4), p. 586–589. doi: 10.1016/j.bbrc.2014.04.043.
  • Asp, Nagham; Pust, Sascha & Sandvig, Kirsten (2014). Flotillin depletion affects ErbB protein levels in different human breast cancer cells. BBA - Molecular Cell Research. ISSN 0167-4889. 1843(9), p. 1987–1996. doi: 10.1016/j.bbamcr.2014.04.013.
  • Yermakova, Anastasiya; Klokk, Tove Irene; Cole, Richard; Sandvig, Kirsten & Mantis, Nicholas J (2014). Antibody-mediated inhibition of ricin toxin retrograde transport. mBio. ISSN 2161-2129. 5(2). doi: 10.1128/mBio.00995-13.
  • Phuyal, Santosh; Hessvik, Nina Pettersen; Skotland, Tore; Sandvig, Kirsten & Llorente, Alicia (2014). Regulation of exosome release by glycosphingolipids and flotillins. The FEBS Journal. ISSN 1742-464X. 281(9), p. 2214–2227. doi: 10.1111/febs.12775.
  • Kavaliauskiene, Simona; Nymark, Carl-Martin; Bergan, Jonas; Simm, Roger; Sylvänne, Tuulia & Simolin, Helena [Show all 9 contributors for this article] (2014). Cell density-induced changes in lipid composition and intracellular trafficking. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 71(6), p. 1097–1116. doi: 10.1007/s00018-013-1441-y.
  • Kvalvaag, Audun Sverre Myrset; Pust, Sascha & Sandvig, Kirsten (2014). Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport. Communicative & Integrative Biology. ISSN 1942-0889. 7. doi: 10.4161/cib.28129.
  • Sandvig, Kirsten; Bergan, Jonas; Kavaliauskiene, Simona & Skotland, Tore (2014). Lipid requirements for entry of protein toxins into cells. Progress in lipid research. ISSN 0163-7827. 54(1), p. 1–13. doi: 10.1016/j.plipres.2014.01.001.
  • Slominska-Wojewodska, Monika; Pawlik, A; Sokolowska, Iwona; Antoniewicz, J; Wegrzyn, Grzegorz & Sandvig, Kirsten (2014). The role of EDEM2 versus EDEM1 in ricin transport fro the endoplasmic reticulum to the cytosol. Biochemical Journal. ISSN 0264-6021. 457(3), p. 485–496. doi: 10.1042/BJ20130155.
  • Pust, Sascha; Klokk, Tove Irene; Musa, Nagham; Jenstad, Monica; Risberg, Bjørn Åke & Erikstein, Bjørn K [Show all 11 contributors for this article] (2013). Flotillins as regulators of ErbB2 levels in breast cancer. Oncogene. ISSN 0950-9232. 32(29), p. 3443–3451. doi: 10.1038/onc.2012.357.
  • Bergan, Jonas; Skotland, Tore; Sylvänne, Tuulia; Simolin, Helena; Ekroos, Kim & Sandvig, Kirsten (2013). The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells. PLOS ONE. ISSN 1932-6203. 8(9). doi: 10.1371/journal.pone.0075904.
  • Llorente, Alicia; Skotland, Tore; Sylvänne, Tuulia; Kauhanen, Dimple; Rog, Tomasz & Orlowski, Adam [Show all 9 contributors for this article] (2013). Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1831(7), p. 1302–1309. doi: 10.1016/j.bbalip.2013.04.011.
  • Slominska-Wojewodska, Monika & Sandvig, Kirsten (2013). Ricin and ricin-containing immunotoxins: insights into intracellular transport and mechanism of action in vitro. Antibodies. ISSN 2073-4468. 2(2), p. 236–269. doi: 10.3390/antib2020236.
  • Hessvik, Nina Pettersen; Sandvig, Kirsten & Llorente, Alicia (2013). Exosomal miRNA as biomarkers for prostate cancer. Frontiers in Genetics. ISSN 1664-8021. p. 1–9. doi: 10.3389/fgene.2013.00036.
  • Sandvig, Kirsten; Skotland, Tore; Van Deurs, Bo & Klokk, Tove Irene (2013). Retrograde transport of protein toxins through the Golgi apparatus. Histochemistry and Cell Biology. ISSN 0948-6143. 140(3), p. 317–326. doi: 10.1007/s00418-013-1111-z.
  • Kvalvaag, Audun Sverre Myrset; Pust, Sascha; Sundet, Kristine Ingrid; Simm, Roger; Sandvig, Kirsten & Engedal, Kim Nikolai (2013). The ERM Proteins Ezrin and Moesin Regulate Retrograde Shiga Toxin Transport. Traffic: The moving front of cell biology. ISSN 1398-9219. 14(7), p. 839–852. doi: 10.1111/tra.12077.
  • Gregers, Tone Fredsvik; Skånland, Sigrid Strand; Waelchli, Sebastien; Bakke, Oddmund & Sandvig, Kirsten (2013). BiP Negatively Affects Ricin Transport. Toxins. ISSN 2072-6651. 5(5), p. 969–982. doi: 10.3390/toxins5050969.
  • Iversen, Tore Geir; Frerker, Nadine & Sandvig, Kirsten (2012). Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism. Journal of Nanobiotechnology. ISSN 1477-3155. 10. doi: 10.1186/1477-3155-10-33.

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  • Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F. & Kildal, Wanja [Show all 16 contributors for this article] (2022). Corrigendum to “Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft”, [Journal of Control Release, 293 (2019) 183–192, (Journal of Control Release, (2019) 293(183-192) (S0168365918306928), (10.1016/j.jconrel.2018.11.029)). Journal of Controlled Release. ISSN 0168-3659. 349. doi: 10.1016/j.jconrel.2022.06.040.
  • Torgersen, Maria Lyngaas; Szwed, Marzena; Sønstevold, Tonje; Øverbye, Anders; Engedal, Nikolai & Grallert, Beata [Show all 11 contributors for this article] (2018). Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death.
  • Rodriguez, Marta; Bajo-Santos, Cristina; Hessvik, Nina Pettersen; Lorenz, Susanne; Fromm, Bastian & Berge, Viktor [Show all 9 contributors for this article] (2017). Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes. Molecular Cancer. ISSN 1476-4598. 16:156, p. 1–6. doi: 10.1186/s12943-017-0726-4.
  • Sulheim, Einar; Iversen, Tore Geir; To, Vu; Klinkenberg, Geir; Sletta, Håvard & Schmid, Ruth [Show all 12 contributors for this article] (2017). Cytotoxicity of Poly (alkyl cyanoacrylate) Nanoparticles.
  • Manna, Dipankar; Krengel, Ute & Sandvig, Kirsten (2016). Structure-function characterization and cytotoxicity studies of fungal chimerolections. NBS-nytt. ISSN 0801-3535.
  • Manna, Dipankar; Cordara, Gabriele; Sandvig, Kirsten & Krengel, Ute (2016). I Robot- Biological nanomachines for fungal defense.
  • Øverbye, Anders; Holsæter, Ann Mari; Skalko-Basnet, Natasa; Tore-Geir, Iversen; Torgersen, Maria Lyngaas & Sønstevold, Tonje [Show all 8 contributors for this article] (2016). Biodegradable nanoparticles in cancer diagnosis and therapy (NANOCAN):Ceramide modulation of liposomal doxorubicin.
  • Manna, Dipankar; Cordara, Gabriele; Pust, Sascha; Goldstein, Irwin J; Winter, Harry C. & Krengel, Ute [Show all 7 contributors for this article] (2015). PSL1a: a new member in the growing family of fungal chimerolectin.
  • Skotland, Tore; Iversen, Tore Geir & Sandvig, Kirsten (2014). Development of nanoparticles for clinical use. Nanomedicine. ISSN 1743-5889. 9(9), p. 1295–1299. doi: 10.2217/NNM.14.81.
  • O'Hara, Joanne; Klokk, Tove Irene; Sandvig, Kirsten & Mantis, Nicholas (2012). RTA-specific monoclonal antibodies neutralize ricin toxin intracellularly. Journal of Immunology. ISSN 0022-1767. 188.
  • Kvalvaag, Audun Sverre Myrset & Sandvig, Kirsten (2015). Shiga toxin: Uptake and transport in cancer cells. Akademika Publishing.
  • Seim Jakobsen, Ida; Llorente, Alicia & Sandvig, Kirsten (2014). Exosome release: Role of PIKfyve and ERM proteins. 7Letras.
  • Svensson, Karin; Klokk, Tove Irene & Sandvig, Kirsten (2014). The role of evectin-2 and its binding partner PS in toxin transport. 7Letras.
  • Sandvig, Kirsten; Simm, Roger & Kymre, LInn (2014). Structure-function relationship of Shiga toxins. Role of the A-subunit in complex stability and endocytosis. 7Letras.
  • Phuyal, Santosh; Llorente, Alicia & Sandvig, Kirsten (2014). Composition and cellular release of exosomes from cancer cells. Akademika publishing.
  • Asp, Nagham; Sandvig, Kirsten; Pust, Sascha & Klokk, Tove Irene (2014). Regulation of ErbB2 and ErbB3 Growth factor receptors in human breast cancer. Akademika Publishing.
  • Cordara, Gabriele; Krengel, Ute & Sandvig, Kirsten (2013). Structure-function studies on the Marasmius oreades agglutinin (MOA), a cytotoxic protease. Akademika Publishing.
  • Sandvig, Kirsten & Bergan, Jonas (2013). Investigation of membrane dynamics in cancer cells by following Shiga toxin. Universitetet i Oslo.
  • Sandvig, Kirsten & Gargul, Anne Grete (2013). In vitro studies of nanosized iron oxide particles. Universitetet i Oslo.
  • Lingelem, Anne Berit Dyve & Sandvig, Kirsten (2012). Intracellular transport of Shiga toxin and ricin. Unipub forlag.

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Published Nov. 4, 2010 2:48 PM - Last modified Aug. 29, 2023 2:37 PM

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