Cell Signaling and Cancer - Saatcioglu
Our research focuses on the molecular mechanisms by which hormones, in particular the male hormone testosterone, regulate intracellular signaling events resulting in cellular responses. In addition, we are interested in stress signaling pathways and their functional role in normal and cancer cells. We are studying how disruption in these signaling events, especially in prostate cancer cells, have disease promotion effects.
Welcome to the Saatcioglu lab
We use molecular, biochemical, cell biological, genetic, and bioinformatics approaches, including preclinical and clinical materials and data sets, to determine how inappropriate regulation of these signaling pathways contributes to tumor progression and treatment resistance. By understanding the molecular and cell biological framework of these signaling events, we aim to identify novel biomarkers and therapeutic targets for cancer, one of the greatest global threats to human health.