Yang Jin

Bilde av Yang Jin
English version of this page
Besøksadresse 0316 OSLO Blindernveien 31
Postadresse Postboks 1066 Blindern 0316 Oslo


Prostate enriched STAMP1 and STAMP2 belong to a family of six transmembrane proteins that share a conserved oxido-reductase domain. We have previously shown that both proteins are critical for prostate cancer cell growth and survival in vitro and in vivo, as well as being associated with prostate cancer progression. My work focuses on exploring the exact functions of STAMPs and the molecular mechanisms underlying their effects in prostate cancer cells.


  • Jin, Yang & Saatcioglu, Fahri (2020). Targeting the unfolded protein response in hormone-regulated cancers. Trends in Cancer.  ISSN 2405-8033.  6(2), s 160- 171 . doi: 10.1016/j.trecan.2019.12.001
  • Zhang, Tingting; Li, Ningning; Sun, Chaoyang; Jin, Yang & Sheng, Xia (2020). MYC and the unfolded protein response in cancer: synthetic lethal partners in crime?. EMBO Molecular Medicine.  ISSN 1757-4676.  12:e11845, s 1- 12 . doi: 10.15252/emmm.201911845
  • Jalili, Mahsa; Jin, Yang; Bones, Atle M.; Olsen, Yngvar; Vadstein, Olav; Østensen, Mari-Ann; Buonocore, Francesco; Gerdol, Marco; Pallavicini, Alberto & Scapigliati, Giuseppe (2019). Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry. Scientific Reports.  ISSN 2045-2322.  9(27), s 1- 16 . doi: 10.1038/s41598-018-37266-3 Fulltekst i vitenarkiv.
  • Pällmann, Nora; Livgård, Marte; Tesikova, Martina; Nenseth, Hatice Zeynep; Akkus, Erman; Sikkeland, Jørgen; Jin, Yixin; Koc, Dogukan; Kuzu, Ömer Faruk; Pradhan, Manohar; Danielsen, Håvard Emil; Kahraman, Nermin; Mokhlis, Hamada M.; Ozpolat, Bulent; Banerjee, Partha P.; Uren, Aykut; Fazli, Ladan; Rennie, Paul S.; Jin, Yang & Saatcioglu, Fahri (2019). Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. Oncogene.  ISSN 0950-9232.  38, s 6301- 6318 . doi: 10.1038/s41388-019-0879-2 Fulltekst i vitenarkiv.
  • Sheng, Xia; Nenseth, Hatice Zeynep; Qu, Su; Kuzu, Ömer Faruk; Frahnow, Turid; Simon, Lukas; Greene, Stephanie; Zeng, Qingping; Fazli, Ladan; Rennie, Paul S.; Mills, Ian Geoffrey; Danielsen, Håvard Emil; Theis, Fabian; Patterson, John B.; Jin, Yang & Saatcioglu, Fahri (2019). IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nature Communications.  ISSN 2041-1723.  10:323, s 1- 12 . doi: 10.1038/s41467-018-08152-3 Fulltekst i vitenarkiv.
  • Shi, Jihua; Guo, Wen-Zhi; Jin, Yang; Zhang, Hua-Peng; Pang, Chun; Li, Jie; Line, Pål Dag & Zhang, Shui-Jun (2019). Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence. Cancer Medicine.  ISSN 2045-7634.  8(3), s 1269- 1278 . doi: 10.1002/cam4.2006 Fulltekst i vitenarkiv.
  • Xu, Cheng; Wang, Yunfei; Tu, Qiu; Zhang, Zhiye; Chen, Mengrou; Mwangi, James; Li, Yaxiong; Jin, Yang; Zhao, Xudong & Lai, Ren (2018). Targeting surface nucleolin induces autophagy-dependent cell death in pancreatic cancer via AMPK activation. Oncogene.  ISSN 0950-9232.  s 1- 13 . doi: 10.1038/s41388-018-0556-x
  • Jin, Yang; Nenseth, Hatice Zeynep & Saatcioglu, Fahri (2017). Role of PLZF as a tumor suppressor in prostate cancer. OncoTarget.  ISSN 1949-2553.  8(41), s 71317- 71324 . doi: 10.18632/oncotarget.19813
  • Cui, Xue-Yan; Tinholt, Mari; Stavik, Benedicte; Dahm, Anders Erik A; Kanse, Sandip; Jin, Yang; Seidl, Sebastian; Sahlberg, Kristine Kleivi; Iversen, Nina; Skretting, Grethe & Sandset, Per Morten (2016). Effect of hypoxia on tissue factor pathway inhibitor expression in breast cancer. Journal of Thrombosis and Haemostasis.  ISSN 1538-7933.  14(2), s 387- 396 . doi: 10.1111/jth.13206
  • Lindstad, Torstein; Qu, Su; Sikkeland, Jørgen; Jin, Yang; Kristian, Alexandr; Mælandsmo, Gunhild; Collas, Philippe & Saatcioglu, Fahri (2016). STAMP2 is required for human adipose-derived stem cell differentiation and adiposite-facilitated prostrate cancer grown in vivo.. OncoTarget.  ISSN 1949-2553.  8(54), s 91817- 91827 . doi: 10.18632/oncotarget.11131
  • Sikkeland, Jørgen; Sheng, Xia; Jin, Yang & Saatcioglu, Fahri (2016). STAMPing at the crossroads of normal physiology and disease states. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  425, s 26- 36 . doi: 10.1016/j.mce.2016.02.013
  • Jin, Yang; Ling, Wang; Qu, Su; Sheng, Xia; Kristian, Alexandr; Mælandsmo, Gunhild; Pällmann, Nora; Yuca, Erkan; Tekedereli, Ibrahim; Gorgulu, Kivanc; Alpay, Neslihan; Sood, Anil K.; Lopez-Berestein, Gabriel; Fazli, Ladan; Rennie, Paul S.; Risberg, Bjørn Åke; Wæhre, Haakon; Danielsen, Håvard Emil; Ozpolat, Bulent & Saatcioglu, Fahri (2015). STAMP2 increases oxidative stress and is critical for prostate cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  7(3), s 315- 331 . doi: 10.15252/emmm.201404181 Fulltekst i vitenarkiv.
  • Sheng, Xia; Arnoldussen, Yke Jildouw; Storm, Margrethe Larsdatter; Tesikova, Martina; Nenseth, Hatice Zeynep; Zhao, Sen; Fazli, Ladan; Rennie, Paul S.; Risberg, Bjørn Åke; Wæhre, Haakon; Danielsen, Håvard Emil; Mills, Ian Geoffrey; Jin, Yang; Hotamisligil, Gökhan S & Saatcioglu, Fahri (2015). Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Molecular Medicine.  ISSN 1757-4676.  7(6), s 788- 801 . doi: 10.15252/emmm.201404509 Fulltekst i vitenarkiv. Vis sammendrag
  • Sikkeland, Jørgen; Jin, Yang & Saatcioglu, Fahri (2014). Methods to assess lipid accumulation in cancer cells. Methods in Enzymology.  ISSN 0076-6879.  542, s 407- 423 . doi: 10.1016/B978-0-12-416618-9.00021-2
  • Jin, Yang; Qu, Su; Tesikova, Martina; Ling, Wang; Kristian, Alexandr; Mælandsmo, Gunhild; Kong, Haiying; Zhang, Tianzhou; Jerónimo, Carmen; Teixeira, Manuel; Yuca, Erkan; Tekedereli, Ibrahim; Gorgulu, Kivanc; Alpay, Nelihan; Sood, Anil K.; Lopez-Berestein, Gabriel; Danielsen, Håvard Emil; Ozpolat, Bulent & Saatcioglu, Fahri (2013). Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  110(28), s E2572- E2581 . doi: 10.1073/pnas.1304318110
  • Lindstad, Torstein; Jin, Yang; Ling, Wang; Qu, Su & Saatcioglu, Fahri (2010). STAMPs at the Crossroads of Cancer and Nutrition. Nutrition and Cancer.  ISSN 0163-5581.  62(7), s 891- 895 . doi: 10.1080/01635581.2010.509836
  • Ling, Wang; Jin, Yang; Arnoldussen, Yke Jildouw; Jonson, Ida; Qu, Su; Mælandsmo, Gunhild; Kristian, Alexandr; Risberg, Bjørn; Wæhre, Haakon; Danielsen, Håvard Emil & Saatcioglu, Fahri (2010). STAMP1 Is Both a Proliferative and an Antiapoptotic Factor in Prostate Cancer. Cancer Research.  ISSN 0008-5472.  70(14), s 5818- 5828 . doi: 10.1158/0008-5472.CAN-09-4697

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Publisert 4. nov. 2010 14:41 - Sist endret 7. juni 2016 15:33