Anders Åsberg

• Ponthier, Laure; Amutmizguine, Julie; Franck, Benedicte; Åsberg, Anders; Ovetchkine, Philippe & Destere, Alexandre [Vis alle 9 forfattere av denne artikkelen] (2024). Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning. Clinical Pharmacokinetics. ISSN 0312-5963. 63(4), s. 539–550. doi: 10.1007/s40262-024-01362-7.
• Helanterä, Ilkka; Dörje, Christina; Ortiz, Fernanda; Reisæter, Anna Varberg; Hammarström, Clara Louise & Lauronen, Jouni [Vis alle 11 forfattere av denne artikkelen] (2024). Very Low Frequency of Pathological Findings in One-year Protocol Biopsies of Uneventful Standard Risk Kidney Transplant Recipients: Results from the Nordic Protocol Biopsy Study. Transplantation direct. ISSN 2373-8731. 10(5). doi: 10.1097/TXD.0000000000001621.
• Ponthier, Laure; Autmizguine, Julie; Franck, Benedicte; Åsberg, Anders; Ovetchkine, Philippe & Destere, Alexandre [Vis alle 9 forfattere av denne artikkelen] (2024). Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning. Clinical Pharmacokinetics. ISSN 0312-5963. doi: 10.1007/s40262-024-01362-7.
• Boerstra, Brittany A.; Boenink, Rianne; Astley, Megan E.; Bonthuis, Marjolein; ElHafeez, Samar Abd & Monzón, Federico Arribas [Vis alle 19 forfattere av denne artikkelen] (2024). The ERA Registry Annual Report 2021: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 17(2). doi: 10.1093/ckj/sfad281.
• Strømmen, Ruth Cecilie; Godang, Kristin; Finnes, Trine Elisabeth; Smerud, Knut Terje; Reisæter, Anna Varberg & Hartmann, Anders [Vis alle 9 forfattere av denne artikkelen] (2023). Trabecular Bone Score Improves Early After Successful Kidney Transplantation Irrespective of Antiresorptive Therapy and Changes in Bone Mineral Density. Transplantation direct. ISSN 2373-8731. 10(1). doi: 10.1097/TXD.0000000000001566. Fulltekst i vitenarkiv
• Kvitne, Kine Eide; Hovd, Markus; Johnsen, Line Kristin; Wegler, Christine; Karlsson, Cecilia & Artursson, Per [Vis alle 14 forfattere av denne artikkelen] (2023). Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals. Clinical Pharmacokinetics. ISSN 0312-5963. doi: 10.1007/s40262-023-01320-9. Fulltekst i vitenarkiv
• Bakkagloglu, Seven A; Vidal, Enrico; Bonthuis, Marjolein; Neto, Gisela; Paripovic, Dusan & Åsberg, Anders [Vis alle 12 forfattere av denne artikkelen] (2023). European chronic kidney disease registries for children not on kidney replacement therapy: tools for improving health systems and patient-centred outcomes. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 16(11), s. 1980–1985. doi: 10.1093/ckj/sfad204. Fulltekst i vitenarkiv
• Vethe, Nils Tore; Åsberg, Anders; Andersen, Anders Mikal; Skauby, Ragnhild Kristine Heier; Bergan, Stein & Midtvedt, Karsten (2023). Clinical performance of volumetric finger-prick sampling for the monitoring of tacrolimus, creatinine and haemoglobin in kidney transplant recipients. British Journal of Clinical Pharmacology. ISSN 0306-5251. 89(12), s. 3690–3701. doi: 10.1111/bcp.15870. Fulltekst i vitenarkiv
• Fløde, Mari; Hermann, Monica; Haugstvedt, Anne; Søfteland, Eirik; Igland, Jannicke & Åsberg, Anders [Vis alle 8 forfattere av denne artikkelen] (2023). High number of hypoglycaemic episodes identified by CGM among home-dwelling older people with diabetes: an observational study in Norway. BMC Endocrine Disorders. ISSN 1472-6823. 23. doi: 10.1186/s12902-023-01472-6. Fulltekst i vitenarkiv
• Kared, Hassen; Alirezaylavasani, Amin; Lund, Kathrine Persgård; Chopra, Adity; Tietze, Lisa & de Matos Kasahara, Taissa [Vis alle 17 forfattere av denne artikkelen] (2023). Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients. EBioMedicine. ISSN 2352-3964. 97. doi: 10.1016/j.ebiom.2023.104833. Fulltekst i vitenarkiv
• Kindem, Ingvild Andrea; Åsberg, Anders; Midtvedt, Karsten & Bjerre, Anna Kristina (2023). Optimizing medication adherence with home-monitoring – A feasibility study using capillary microsampling and mHealth in solid organ-transplanted adolescents. Pediatric Transplantation. ISSN 1397-3142. 27(7). doi: 10.1111/petr.14590. Fulltekst i vitenarkiv
• Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Soeren & Mollnes, Tom Eirik [Vis alle 11 forfattere av denne artikkelen] (2023). Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study. Frontiers in Immunology. ISSN 1664-3224. 14. doi: 10.3389/fimmu.2023.1253991. Fulltekst i vitenarkiv
• Handin, Niklas; Yuan, Di; Ölander, Magnus; Wegler, Christine; Karlsson, Cecilia & Jansson-Löfmark, Rasmus [Vis alle 10 forfattere av denne artikkelen] (2023). Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis. Computational and Structural Biotechnology Journal. ISSN 2001-0370. 21, s. 4361–4369. doi: 10.1016/j.csbj.2023.08.037. Fulltekst i vitenarkiv Vis sammendrag

  Human liver tissue is composed of heterogeneous mixtures of different cell types and their cellular stoichiometry can provide information on hepatic physiology and disease progression. Deconvolution algorithms for the identification of cell types and their proportions have recently been developed for transcriptomic data. However, no method for the deconvolution of bulk proteomics data has been presented to date. Here, we show that proteomes, which usually contain less data than transcriptomes, can provide useful information for cell type deconvolution using different algorithms. We demonstrate that proteomes from defined mixtures of cell lines, isolated primary liver cells, and human liver biopsies can be deconvoluted with high accuracy. In contrast to transcriptome-based deconvolution, liver tissue proteomes also provided information about extracellular compartments. Using deconvolution of proteomics data from liver biopsies of 56 patients undergoing Roux-en-Y gastric bypass surgery we show that proportions of immune and stellate cells correlate with inflammatory markers and altered composition of extracellular matrix proteins characteristic of early-stage fibrosis. Our results thus demonstrate that proteome deconvolution can be used as a molecular microscope for investigations of the composition of cell types, extracellular compartments, and for exploring cell-type specific pathological events. We anticipate that these findings will allow the refinement of retrospective analyses of the growing number of proteome datasets from various liver disease states and pave the way for AI-supported clinical and preclinical diagnostics.

• Kipp, Anne Christina; Marti, Hans Peter; Babickova, Janka; Nakken, Sigrid; Leh, Sabine & Strøm Halden, Thea Anine [Vis alle 11 forfattere av denne artikkelen] (2023). Glomerular proteomic profiling reveals early differences between preexisting and de novo type 2 diabetes in human renal allografts. BMC Nephrology. ISSN 1471-2369. 24. doi: 10.1186/s12882-023-03294-z. Fulltekst i vitenarkiv
• Thorsen, Inga Strand; Bleskestad, Inger Hjørdis; Åsberg, Anders; Jonsson, Grete; Skadberg, Øyvind & Heldal, Kristian [Vis alle 7 forfattere av denne artikkelen] (2023). Klotho and Fibroblast Growth Factor 23 Are Independent of Vitamin D, and Unlike Vitamin D, Are Not Associated With Graft- and Patient Survival After Kidney Transplantation. Transplantation direct. ISSN 2373-8731. 9(9). doi: 10.1097/TXD.0000000000001522. Fulltekst i vitenarkiv
• Astley, Megan E; Boenink, Rianne; ElHafeez, Samar Abd; Trujillo-Aleman, Sara; Arribas, Federico & Åsberg, Anders [Vis alle 36 forfattere av denne artikkelen] (2023). The ERA Registry Annual Report 2020: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 16(8), s. 1330–1354. doi: 10.1093/ckj/sfad087. Fulltekst i vitenarkiv
• Åsberg, Anders; Hovd, Markus Herberg; Kjellevold, Stig Arne; Stenehjem, Aud Eldrid; Wien, Tale Norbye & Broch, Lars Ulrik [Vis alle 15 forfattere av denne artikkelen] (2023). Humoral Response After 6 or More Successive Doses of SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients-Should We Keep Vaccinating? Transplantation. ISSN 0041-1337. 107(10), s. e279–e280. doi: 10.1097/TP.0000000000004732. Fulltekst i vitenarkiv
• Vinknes, Kathrine Jørgensen; Olsen, Thomas; Zare, Hasse Khiabani; Bastani, Nasser Ezzatkhah; Stolt, Emma Theresia Kjelland & Dahl, Anja Falkenhaug [Vis alle 11 forfattere av denne artikkelen] (2023). Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study. Diabetes, obesity and metabolism. ISSN 1462-8902. 25(11), s. 3161–3170. doi: 10.1111/dom.15210. Fulltekst i vitenarkiv
• Blom, Kjersti Benedicte; Kro, Grete Anette Birkeland; Midtvedt, Karsten; Jenssen, Trond; Reisæter, Anna Varberg & Rollag, Halvor [Vis alle 15 forfattere av denne artikkelen] (2023). Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management. Transplantation. ISSN 0041-1337. 107(8), s. 1846–1853. doi: 10.1097/TP.0000000000004615. Fulltekst i vitenarkiv
• Hovd, Markus Herberg; Åsberg, Anders; Munthe, Ludvig Andre; Heldal, Kristian; Reisæter, Anna Varberg & Vaage, John T. [Vis alle 8 forfattere av denne artikkelen] (2023). Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study. EClinicalMedicine. ISSN 2589-5370. 60. doi: 10.1016/j.eclinm.2023.102035. Fulltekst i vitenarkiv
• Kvitne, Kine Eide; Drevland, Ole Martin; Haugli, Nora; Skadberg, Eline Supannee Setu; Zare, Hasse Khiabani & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2023). Intraindividual Variability in Absolute Bioavailability and Clearance of Midazolam in Healthy Individuals. Clinical Pharmacokinetics. ISSN 0312-5963. 62(7), s. 981–987. doi: 10.1007/s40262-023-01257-z. Fulltekst i vitenarkiv
• Boenink, Rianne; Kramer, Anneke; Tuinhout, Rosalie E.; Savoye, Emilie; Åsberg, Anders & Idrizi, Alma [Vis alle 38 forfattere av denne artikkelen] (2023). Trends in kidney transplantation rate across Europe: study from the ERA Registry. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 38(6), s. 1528–1539. doi: 10.1093/ndt/gfac333. Fulltekst i vitenarkiv
• Drevland, Ole Martin; Robertsen, Ida; Gustavsen, Marte Theie; Kveim, Hanne Kamilla; Hovd, Markus Herberg & Midtvedt, Karsten [Vis alle 7 forfattere av denne artikkelen] (2023). Impact of Fasting Status and Circadian Variation on the Pharmacokinetics of Mycophenolate Mofetil and the Glucuronide Metabolite in Renal Transplant Recipients. Transplantation direct. ISSN 2373-8731. 9(3). doi: 10.1097/TXD.0000000000001448. Fulltekst i vitenarkiv
• Hovd, Markus Herberg; Robertsen, Ida; Woillard, Jean-Baptiste & Åsberg, Anders (2023). A Method for Evaluating Robustness of Limited Sampling Strategies—Exemplified by Serum Iohexol Clearance for Determination of Measured Glomerular Filtration Rate. Pharmaceutics. ISSN 1999-4923. 15(4). doi: 10.3390/pharmaceutics15041073. Fulltekst i vitenarkiv
• Bleskestad, Inger Hjørdis; Skadberg, Øyvind; Åsberg, Anders & Gøransson, Lasse Gunnar (2023). Glycated albumin and post-transplant diabetes mellitus in kidney transplant recipients. Annals of Clinical Biochemistry. ISSN 0004-5632. 60(2), s. 109–116. doi: 10.1177/00045632231152074.
• Hovd, Markus Herberg; Robertsen, Ida; Johnson, Line Kristin; Krogstad, Veronica; Wegler, Christine & Kvitne, Kine Eide [Vis alle 16 forfattere av denne artikkelen] (2023). Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance. Clinical Pharmacokinetics. ISSN 0312-5963. 62(5), s. 725–735. doi: 10.1007/s40262-023-01235-5. Fulltekst i vitenarkiv
• Kindem, Ingvild Andrea; Bjerre, Anna Kristina; Hammarström, Clara Louise; Naper, Christian; Midtvedt, Karsten & Åsberg, Anders (2022). Kidney-transplanted Adolescents—Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000–2020. Transplantation. ISSN 0041-1337. 107(5), s. 1206–1212. doi: 10.1097/TP.0000000000004431. Fulltekst i vitenarkiv
• Rossignol, P; Duarte, K.; Bresso, E; Åsberg, Anders; Devignes, DM & Eriksson, N [Vis alle 22 forfattere av denne artikkelen] (2022). NT-proBNP and stem cell factor plasma concentrations are independently associated with cardiovascular outcomes in end-stage renal disease hemodialysis patients. European Heart Journal Open (EHJ Open). 2(6). doi: 10.1093/ehjopen/oeac069. Fulltekst i vitenarkiv
• Tran, Trung; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa & Kolderup, Heidi Anette [Vis alle 40 forfattere av denne artikkelen] (2022). Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants. npj Vaccines. ISSN 2059-0105. 7(1). doi: 10.1038/s41541-022-00586-7. Fulltekst i vitenarkiv
• Hemmelder, Marc H.; Noordzij, Marlies; Vart, Priya; Hilbrands, Luuk B.; Jager, Kitty J. & Abrahams, Alferso C. [Vis alle 233 forfattere av denne artikkelen] (2022). Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 37(6), s. 1140–1151. doi: 10.1093/ndt/gfac008.
• Storås, Andrea; Åsberg, Anders; Halvorsen, Pål; Riegler, Michael Alexander & Strumke, Inga (2022). Predicting Tacrolimus Exposure in Kidney Transplanted Patients Using Machine Learning. I Shen, Linlin; González, Alejandro Rodríguez; Santosh, KC; Lai, Zhihui; Sicilia, Rosa; Almeida, João Rafael & Kane, Bridget (Red.), 2022 IEEE 35th International Symposium on Computer-Based Medical Systems (CBMS). IEEE (Institute of Electrical and Electronics Engineers). ISSN 978-1-6654-6770-4. s. 38–43. doi: 10.1109/CBMS55023.2022.00014. Fulltekst i vitenarkiv
• Vart, Priya; Duivenvoorden, Raphaël; Adema, Aaltje; Covic, Adrian; Finne, Patrik & Braak, Nicole Heijtink-ter [Vis alle 235 forfattere av denne artikkelen] (2022). Sex differences in COVID-19 mortality risk in patients on kidney function replacement therapy. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-22657-4.
• Tsarpali, Vasiliki; Midtvedt, Karsten; Lønning, Kjersti; Bernklev, Tomm; Åsberg, Anders & Lippe, Nanna von der [Vis alle 8 forfattere av denne artikkelen] (2022). Poor physical function trajectory predicts impaired patient survival in older recipients of deceased donor kidneys: A prospective cohort study. Transplantation direct. ISSN 2373-8731. 8(11). doi: 10.1097/TXD.0000000000001374. Fulltekst i vitenarkiv Vis sammendrag

  Optimized health-related quality of life (HRQOL) at the time of kidney transplantation (KT) is associated with improved survival. In older KT recipients, we aimed to prospectively evaluate if HRQOL evolution during the first posttransplant year was associated with long-term patient survival. Methods: Recipients older than 65 y at KT who received an organ from a deceased brain-dead donor and survived >12 mo posttransplant were eligible. HRQOL was assessed pre-KT, at 10 wk, 6 mo, and 12 mo post-KT, using the Kidney Disease Quality of Life Short Form version 1.3 survey. A mixed-effect model was used to explore HRQOL evolution during the first posttransplant year in long-term survivors compared with nonsurvivors. Distinct HRQOL clusters were identified using a group-based trajectory modeling and their association with patient survival was investigated with Cox proportional hazard regression models. Results: We included 192 elderly recipients of deceased brain-dead donor kidneys who were transplanted from 2013 to 2020. Eleven died during the first year leaving 181 for evaluation (male, 125; mean age at KT, 72 y [65-84 y]). During a median observation time post-KT of 4.9 y (11.1-8.5 y), 57 recipients died. In survivors, all the generic and kidney-specific HRQOL domains substantially improved during the first year, whereas in nonsurvivors HRQOL deteriorated. Three longitudinal HRQOL trajectories indicating poor, fair, and good HRQOL evolution were identified. Poor physical function trajectory was significantly associated with higher mortality risk independent of covariates, as compared with good physical trajectory (hazard ratio, 2.38; 95% confidence interval, 1.15-5.01). Conclusions: In elderly KT recipients, detection of declining posttransplant physical function may imply impaired survival. Systematic HRQOL monitoring following KT provides added value when evaluating mortality and may guide therapeutic decisions.

• Kvitne, Kine Eide; Åsberg, Anders; Johnson, Line Kristin; Wegler, Christine; Hertel, Jens Kristoffer & Artursson, Per [Vis alle 14 forfattere av denne artikkelen] (2022). Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity. Clinical and Translational Science (CTS). ISSN 1752-8054. 15(11), s. 2685–2696. doi: 10.1111/cts.13394. Fulltekst i vitenarkiv Vis sammendrag

  Previous studies have not accounted for the close link between type 2 diabetes mellitus (T2DM) and obesity when investigating the impact of T2DM on cytochrome P450 (CYP) activities. The aim was to investigate the effect of T2DM on in vivo activities and protein expressions of CYP2C19, CYP3A, CYP1A2, and CYP2C9 in patients with obesity. A total of 99 patients from the COCKTAIL study (NCT02386917) were included in this cross-sectional analysis; 29 with T2DM and obesity (T2DM-obesity), 53 with obesity without T2DM (obesity), and 17 controls without T2DM and obesity (controls). CYP activities were assessed after the administration of a cocktail of probe drugs including omeprazole (CYP2C19), midazolam (CYP3A), caffeine (CYP1A2), and losartan (CYP2C9). Jejunal and liver biopsies were also obtained to determine protein concentrations of the respective CYPs. CYP2C19 activity and jejunal CYP2C19 concentration were 63% (−0.39 [95% CI: −0.82, −0.09]) and 40% (−0.09 fmol/μg protein [95% CI: −0.18, −0.003]) lower in T2DM-obesity compared with the obesity group, respectively. By contrast, there were no differences in the in vivo activities and protein concentrations of CYP3A, CYP1A2, and CYP2C9. Multivariable regression analyses also indicated that T2DM was associated with interindividual variability in CYP2C19 activity, but not CYP3A, CYP1A2, and CYP2C9 activities. The findings indicate that T2DM has a significant downregulating impact on CYP2C19 activity, but not on CYP3A, CYP1A2, and CYP2C9 activities and protein concentrations in patients with obesity. Hence, the effect of T2DM seems to be isoform-specific.

• Destere, Alexandre; Marquet, Pierre; Gandonnière, Charlotte Salmon; Åsberg, Anders; Loustaud-Ratti, Véronique & Carrier, Paul [Vis alle 10 forfattere av denne artikkelen] (2022). A Hybrid Model Associating Population Pharmacokinetics with Machine Learning: A Case Study with Iohexol Clearance Estimation. Clinical Pharmacokinetics. ISSN 0312-5963. 61(8), s. 1157–1165. doi: 10.1007/s40262-022-01138-x.
• Khan, Sana Ahsan; Åsberg, Anders & Jenssen, Trond Geir (2022). Anticoagulation and safety of renal transplant biopsy. Clinical Transplantation. ISSN 0902-0063. 36(8). doi: 10.1111/ctr.14715.
• Gjerstad, Ann Christin; Skrunes, Rannveig; Tøndel, Camilla; Åsberg, Anders; Leh, Sabine & Klingenberg, Claus Andreas [Vis alle 9 forfattere av denne artikkelen] (2022). Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up. Pediatric nephrology (Berlin, West). ISSN 0931-041X. 38(4), s. 1249–1256. doi: 10.1007/s00467-022-05706-y. Fulltekst i vitenarkiv
• Tantisattamo, Ekamol; Imhof, Celine; Jager, Kitty J.; Hilbrands, Luuk B.; Guidotti, Rebecca & Islam, Mahmud [Vis alle 18 forfattere av denne artikkelen] (2022). Association of obesity with 3-month mortality in kidney failure patients with COVID-19. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 15(7), s. 1348–1360. doi: 10.1093/ckj/sfac083.
• Duivenvoorden, Raphael; Vart, Priya; Noordzij, Marlies; Soares dos Santos, Augusto C.; Zulkarnaev, Alexey B. & Franssen, Casper F.M. [Vis alle 20 forfattere av denne artikkelen] (2022). Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of COVID-19. Transplantation. ISSN 0041-1337. 106(5), s. 1012–1023. doi: 10.1097/TP.0000000000004075.
• Kvitne, Kine Eide; Hole, Kristine; Krogstad, Veronica; Wollmann, Birgit Malene Tovik; Wegler, Christine & Johnson, Line Kristin [Vis alle 19 forfattere av denne artikkelen] (2022). Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range. European Journal of Clinical Pharmacology. ISSN 0031-6970. 78(8), s. 1289–1299. doi: 10.1007/s00228-022-03336-9. Fulltekst i vitenarkiv Vis sammendrag

  Purpose Variability in cytochrome P450 3A4 (CYP3A4) metabolism is mainly caused by non-genetic factors, hence providing a need for accurate phenotype biomarkers. Although 4β-hydroxycholesterol (4βOHC) is a promising endogenous CYP3A4 biomarker, additional investigations are required to evaluate its ability to predict CYP3A4 activity. This study investigated the correlations between 4βOHC concentrations and hepatic and intestinal CYP3A4 protein expression and ex vivo microsomal activity in paired liver and jejunum samples, as well as in vivo CYP3A4 phenotyping (midazolam) in patients with a wide body weight range. Methods The patients (n = 96; 78 with obesity and 18 normal or overweight individuals) were included from the COCKTAIL-study (NCT02386917). Plasma samples for analysis of 4βOHC and midazolam concentrations, and liver (n = 56) and jejunal (n = 38) biopsies were obtained. The biopsies for determination of CYP3A4 protein concentration and microsomal activity were obtained during gastric bypass or cholecystectomy. In vivo CYP3A4 phenotyping was performed using semi-simultaneous oral (1.5 mg) and intravenous (1.0 mg) midazolam. Results 4βOHC concentrations were positively correlated with hepatic microsomal CYP3A4 activity (ρ = 0.53, p < 0.001), and hepatic CYP3A4 concentrations (ρ = 0.30, p = 0.027), but not with intestinal CYP3A4 concentrations (ρ = 0.18, p = 0.28) or intestinal microsomal CYP3A4 activity (ρ = 0.15, p = 0.53). 4βOHC concentrations correlated weakly with midazolam absolute bioavailability (ρ =  − 0.23, p = 0.027) and apparent oral clearance (ρ = 0.28, p = 0.008), but not with systemic clearance (ρ =  − 0.03, p = 0.81). Conclusion These findings suggest that 4βOHC concentrations reflect hepatic, but not intestinal, CYP3A4 activity. Further studies should investigate the potential value of 4βOHC as an endogenous biomarker for individual dose requirements of intravenously administered CYP3A4 substrate drugs.

• Destere, Alexandre; Gandonniere, Charlotte Salmon; Åsberg, Anders; Loustaud-Ratti, Véronique; Carrier, Paul & Ehrmann, Stephan [Vis alle 9 forfattere av denne artikkelen] (2022). A single Bayesian estimator for iohexol clearance estimation in ICU, liver failure and renal transplant patients. British Journal of Clinical Pharmacology. ISSN 0306-5251. 88(6), s. 2793–2801. doi: 10.1111/bcp.15197.
• Kvitne, Kine Eide; Krogstad, Veronica; Wegler, Christine; Johnson, Line Kristin; Kringen, Marianne K. & Hovd, Markus Herberg [Vis alle 19 forfattere av denne artikkelen] (2022). Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity. British Journal of Clinical Pharmacology. ISSN 0306-5251. 88(9), s. 4121–4133. doi: 10.1111/bcp.15349. Fulltekst i vitenarkiv Vis sammendrag

  Roux-en-Y gastric bypass (RYGB) may influence drug disposition due to surgery-induced gastrointestinal alterations and/or subsequent weight loss. The objective was to compare short- and long-term effects of RYGB and diet on the metabolic ratios of paraxanthine/caffeine (cytochrome P450 [CYP] 1A2 activity), 5-hydroxyomeprazole/omeprazole (CYP2C19 activity) and losartan/losartan carboxylic acid (CYP2C9 activity), and cross-sectionally compare these CYP-activities with normal-to-overweight controls. Methods This trial included patients with severe obesity preparing for RYGB (n = 40) or diet-induced (n = 41) weight loss, and controls (n = 18). Both weight loss groups underwent a 3-week low-energy diet (<1200 kcal/day, weeks 0-3) followed by a 6-week very-low-energy diet or RYGB (both <800 kcal/day, weeks 3-9). Follow-up time was 2 years, with four pharmacokinetic investigations. Results Mean ± SD weight loss from baseline was similar in the RYGB-group (13 ± 2.4%) and the diet group (10.5 ± 3.9%) at week 9, but differed at year 2 (RYGB −30 ± 6.9%, diet −3.1 ± 6.3%). From weeks 0 to 3, mean (95% confidence interval [CI]) CYP2C19 activity similarly increased in both groups (RYGB 43% [16, 55], diet 48% [22, 60]). Mean CYP2C19 activity increased by 30% (2.6, 43) after RYGB (weeks 3-9), but not in the diet-group (between-group difference −0.30 [−0.63, 0.03]). CYP2C19 activity remained elevated in the RYGB group at year 2. Baseline CYP2C19 activity was 2.7-fold higher in controls compared with patients with obesity, whereas no difference was observed in CYP1A2 and CYP2C9 activities. Conclusion Our findings suggest that CYP2C19 activity is lower in patients with obesity and increases following weight loss. This may be clinically relevant for drug dosing. No clinically significant effect on CYP1A2 and CYP2C9 activities was observed.

• Krogstad, Veronica; Elgstøen, Katja B. Prestø; Johnsen, Linda Flaa; Hartmann, Anders; Mørkrid, Lars & Åsberg, Anders (2022). High Plasma Oxalate Levels Early After Kidney Transplantation Are Associated With Impaired Long-Term Outcomes. Transplant International. ISSN 0934-0874. 35. doi: 10.3389/ti.2022.10240. Fulltekst i vitenarkiv Vis sammendrag

  Background: Elevated levels of oxalate are common in renal failure patients and non-hyperoxaluria disease, and may cause damage after transplantation. We examined outcomes after 15 years for 167 kidney transplant recipients who had plasma oxalate measured early after transplantation. Analyses included plasma oxalate, recipient age, donor age, live donor, HLA-DR mismatch, mGFR, and smoking. Results: Median age was 52 years (range 18–81), 63% were male and 38% had live donors. Median plasma oxalate concentration 10 weeks after transplantation was 9.0 μmol/L (range 2.7–53.0), one third above the upper reference limit (11.0 μmol/L). Multivariable analysis revealed upper quartile plasma oxalate (>13.0 μmol/L, p = 0.008), recipient age (p < 0.001), deceased donor (p = 0.003), and current smoking (p < 0.001) as significant factors associated with patient survival. Upper quartile plasma oxalate (p = 0.021), recipient age (p = 0.001), deceased donor kidney (p = 0.001), HLA-DR mismatch (p = 0.015), and current smoking (p = 0.014) were also associated with graft loss. Factors associated with death censored graft losses were donor age (p = 0.012), deceased donor (p = 0.032), and HLA-DR mis-matched kidneys (p = 0.005) but plasma oxalate was not (p = 0.188). Conclusions: Plasma oxalate in the upper quartile early after transplantation was significantly associated with impaired long-term patient survival and graft losses, but not when censored for death.

• Tsarpali, Vasiliki; Midtvedt, Karsten; Lønning, Kjersti; Bernklev, Tomm; Åsberg, Anders & Fawad, Haris [Vis alle 10 forfattere av denne artikkelen] (2022). A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study. Transplantation direct. ISSN 2373-8731. 8(4). doi: 10.1097/TXD.0000000000001307. Fulltekst i vitenarkiv Vis sammendrag

  Kidney transplantation (KT) is considered the best treatment for end-stage kidney disease (ESKD). In the increasing elderly ESKD population, KT should be reserved for carefully selected candidates who are expected to experience favorable outcomes. We aimed to prospectively evaluate pretransplant recipient factors that may predict patient survival and can eventually guide therapeutic decisions in elderly with ESKD. Methods: Recipient factors were evaluated in KT candidates aged ≥65 y. Comorbidity was assessed at waitlisting according to the Liu comorbidity index (LCI). Health-related quality of life outcomes were measured using the Kidney Disease Quality of Life Short Form, version 1.3. The Cox proportional hazard regression was used to evaluate predictors of patient survival. Results: We included 192 recipients, with a mean age of 72.1 (4.1) y, who were transplanted with kidneys from deceased brain-dead donors. During a median observation period of 4.6 (3.2-6.3) y, 66 recipients died. Elevated LCI consistently predicted poor patient survival. In recipients with LCI ≥4, dialysis >2 y comprised a 2.5-fold increase in mortality risk compared with recipients on dialysis ≤2 y. Self-reported pretransplant physical function was also proven to be a significant positive predictor of survival. Conclusion: The implementation of LCI and a physical function score during the evaluation of older kidney transplant candidates may improve the selection and thereby optimize posttransplant outcomes.

• Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Søren Erik & Mollnes, Tom Eirik [Vis alle 10 forfattere av denne artikkelen] (2022). Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality. American Journal of Transplantation. ISSN 1600-6135. 22, s. 2016–2027. doi: 10.1111/ajt.17047. Fulltekst i vitenarkiv Vis sammendrag

  In the general population low-grade inflammation has been established as a risk factor for all-cause mortality. We hypothesized that an inflammatory milieu beyond the time of recovery from the surgical trauma could be associated with increased long-term mortality in kidney transplant recipients (KTRs). This cohort study included 1044 KTRs. Median follow-up time post-engraftment was 10.3 years. Inflammation was assessed 10 weeks after transplantation by different composite inflammation scores based on 21 biomarkers. We constructed an overall inflammation score and five pathway-specific inflammation scores (fibrogenesis, vascular inflammation, metabolic inflammation, growth/angiogenesis, leukocyte activation). Mortality was assessed with Cox regression models adjusted for traditional risk factors. A total of 312 (29.9%) patients died during the follow-up period. Hazard ratio (HR) for death was 4.71 (95% CI:2.85-7.81, p

• Wegler, Christine; Wisniewski, Jacek R.; Robertsen, Ida; Christensen, Hege; Hertel, Jens Kristoffer & Hjelmesæth, Jøran Sture [Vis alle 10 forfattere av denne artikkelen] (2022). Drug disposition protein quantification in matched human jejunum and liver from donors with obesity. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 111(5), s. 1142–1154. doi: 10.1002/cpt.2558. Fulltekst i vitenarkiv Vis sammendrag

  Mathematical models, such as physiologically based pharmacokinetic (PBPK) models, are used to predict e.g., drug disposition and toxicity. However, populations differ in the abundance of proteins involved in these processes. To improve the building and refinement of such models, they must take into account these inter-individual variabilities. In this study, we used global proteomics to characterize the protein composition of jejunum and liver from 37 donors with obesity enrolled in the COCKTAIL study. Liver protein levels from the 37 donors were further compared with those from donors without obesity. We quantified thousands of proteins and could present the expression of several drug-metabolizing enzymes, for the first time, in jejunum, many of which belong to the cytochrome P450 (e.g., CYP2U1) and the amine oxidase [flavin-containing] (e.g., MAOA) families. Although we show that many metabolizing enzymes had greater expression in liver, others had higher expression in jejunum (such as, MAOA and CES2), indicating the role of the small intestine in extrahepatic drug metabolism. We further show that proteins involved in drug disposition are not correlated in the two donor-matched tissues. These proteins also do not correlate with physiological factors such as BMI, age, and inflammation status in either tissue. Furthermore, the majority of these proteins are not differently expressed in donors with or without obesity. Nonetheless, inter-individual differences were considerable, with implications for personalized prediction models and systems pharmacology.

• Rønning, Marit; Hjellvik, Vidar; Sakshaug, Solveig; Blix, Hege Salvesen; Midtvedt, Karsten & Reisæter, Anna Varberg [Vis alle 8 forfattere av denne artikkelen] (2022). Use of Statins in Kidney Transplant Recipients in Norway . International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 19(3). doi: 10.3390/ijerph19031370. Fulltekst i vitenarkiv
• Blom, Kjersti Benedicte; Åsberg, Anders; Sjaastad, Ivar; Kalleberg, Karl Trygve; Søraas, Arne Vasli & Midtvedt, Karsten [Vis alle 7 forfattere av denne artikkelen] (2021). Kidney Transplant Recipient Behavior During the Early COVID-19 Pandemic: A National Survey Study in Norway. Kidney Medicine. 4(2). doi: 10.1016/j.xkme.2021.09.006. Fulltekst i vitenarkiv
• Heldal, Kristian; Åsberg, Anders; Abedini, Sadollah; Jenssen, Trond Geir; Reisæter, Anna Varberg & Bergan, Stein [Vis alle 7 forfattere av denne artikkelen] (2021). Estimert glomerulær filtrasjonshastighet som mål på nyrefunksjon. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 142(1), s. 48–51. doi: 10.4045/tidsskr.21.0501. Fulltekst i vitenarkiv Vis sammendrag

  Estimert glomerulær filtrasjonshastighet er etablert som klinisk rutinemål for nyrefunksjon, men estimatet har begrensninger og kan ikke brukes i alle kliniske situasjoner. Estimert glomerulær filtrasjonshastighet har en høy variasjonskoeffisient, og ved avvik i pasientens høyde, vekt eller muskelmasse kan estimatet bli unøyaktig. Hvis det er avgjørende å ha et nøyaktig mål på nyrefunksjonen, kan man måle glomerulær filtrasjonshastighet ved hjelp av en eksogen substans.

• Jager, Kitty J; Åsberg, Anders; Collart, Frédéric; Couchoud, Cécile; Evans, Marie & Finne, Patrik [Vis alle 9 forfattere av denne artikkelen] (2021). A snapshot of European registries on chronic kidney disease patients not on kidney replacement therapy. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 37(1), s. 8–13. doi: 10.1093/ndt/gfab252. Fulltekst i vitenarkiv
• Langberg, Nina Elisabeth Borthen; Jenssen, Trond Geir; Haugen, Anders; Mjøen, Geir; Birkeland, Kåre Inge & Åsberg, Anders [Vis alle 8 forfattere av denne artikkelen] (2021). Endothelial Dysfunction and 6-Year Risk of Mortality in Kidney Transplant Recipients. Transplantation direct. ISSN 2373-8731. 8(1), s. 1–6. doi: 10.1097/TXD.0000000000001262. Fulltekst i vitenarkiv
• Stillemans, Gabriel; Paquot, Adrien; Muccioli, Giulio G.; Hoste, Emilia; Panin, Nadtha & Åsberg, Anders [Vis alle 9 forfattere av denne artikkelen] (2021). Atorvastatin population pharmacokinetics in a real-life setting: Influence of genetic polymorphisms and association with clinical response. Clinical and Translational Science (CTS). ISSN 1752-8054. 15(3), s. 667–679. doi: 10.1111/cts.13185. Fulltekst i vitenarkiv
• Ville, Simon; Lorent, Marine; Kerleau, Clarisse; Åsberg, Anders; Legendre, Chrostopher & Morelon, Emmanuel [Vis alle 18 forfattere av denne artikkelen] (2021). Timing of Kidney Clamping and Deceased Donor Kidney Transplant Outcomes. American Society of Nephrology. Clinical Journal. ISSN 1555-9041. 16(11), s. 1704–1714. doi: 10.2215/CJN.03290321.
• Montero, Nuria; Toapanta, Néstor; Pallarès, Natàlia; Crespo, Marta; Diekmann, Fritz & Guirado, Lluis [Vis alle 25 forfattere av denne artikkelen] (2021). Deciphering transplant outcomes of expanded kidney allografts donated after controlled circulatory death in the current transplant era. A call for caution. Transplant International. ISSN 0934-0874. 34(12), s. 2494–2506. doi: 10.1111/tri.14131.
• Witczak, Bartlomiej J; Pischke, Søren E.; Reisæter, Anna V.; Midtvedt, Karsten; Ludviksen, Judith K & Heldal, Kristian [Vis alle 10 forfattere av denne artikkelen] (2021). Elevated Terminal C5b-9 Complement Complex 10 Weeks Post Kidney Transplantation Was Associated With Reduced Long-Term Patient and Kidney Graft Survival. Frontiers in Immunology. ISSN 1664-3224. 12. doi: 10.3389/fimmu.2021.738927. Fulltekst i vitenarkiv
• Bleskestad, Kristiane Birkeland; Nordheim, Espen; Lindahl, Jørn Petter Hanto; Midtvedt, Karsten; Pihlstrøm, Hege K. & Horneland, Rune [Vis alle 10 forfattere av denne artikkelen] (2021). Insulin secretion and action after pancreas transplantation. A retrospective single-center study. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 81(5), s. 365–370. doi: 10.1080/00365513.2021.1926535. Fulltekst i vitenarkiv
• Kvitne, Kine Eide; Robertsen, Ida; Skovlund, Eva; Christensen, Hege Staaland; Krogstad, Veronica & Wegler, Christine [Vis alle 18 forfattere av denne artikkelen] (2021). Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity – a non-randomized three-armed controlled trial. Clinical and Translational Science (CTS). ISSN 1752-8054. doi: 10.1111/cts.13142. Fulltekst i vitenarkiv
• Jørgensen, Hanne Skou; Eide, Ivar Anders; Jenssen, Trond; Åsberg, Anders; Bollerslev, Jens & Godang, Kristin [Vis alle 9 forfattere av denne artikkelen] (2021). Marine n-3 polyunsaturated fatty acids and bone mineral density in kidney transplant recipients: A randomized, placebo-controlled trial. Nutrients. ISSN 2072-6643. 13(7). doi: 10.3390/nu13072361. Fulltekst i vitenarkiv
• Franck, Bénédicte; Autmizguine, Julie; Åsberg, Anders; Théorêt, Yves; Marquet, Pierre & Ovetchkine, Philippe [Vis alle 7 forfattere av denne artikkelen] (2021). Thoroughly validated Bayesian estimator and limited sampling strategy for dose Individualization of ganciclovir and valganciclovir in pediatric transplant recipients. Clinical Pharmacokinetics. ISSN 0312-5963. 60(11), s. 1449–1462. doi: 10.1007/s40262-021-01034-w.
• Jakulj, Lily; Kramer, Anneke; Åsberg, Anders; de Meester, Johan; de Pablos, Carmen Santiuste & Helve, Jaakko [Vis alle 19 forfattere av denne artikkelen] (2021). Recovery of kidney function in patients treated with maintenance dialysis—a report from the ERA-EDTA Registry. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 36(6), s. 1078–1087. doi: 10.1093/ndt/gfaa368.
• Kindem, Ingvild Andrea; Bjerre, Anna Kristina; Åsberg, Anders; Midtvedt, Karsten; Bergan, Stein & Vethe, Nils Tore (2021). Tacrolimus Measured in Capillary Volumetric Microsamples in Pediatric Patients—A Cross-Validation Study. Therapeutic Drug Monitoring. ISSN 0163-4356. 43(3), s. 371–375. doi: 10.1097/FTD.0000000000000873. Fulltekst i vitenarkiv
• Onsøien, Mari Olsen; Midtvedt, Karsten; Reisæter, Anna Varberg; Aasarød, Knut; Waldum-Grevbo, Bård & Vikse, Bjørn Egil [Vis alle 8 forfattere av denne artikkelen] (2021). Blood Pressure Treatment in Kidney Transplant Recipients—Can We Improve? Transplantation direct. ISSN 2373-8731. 7(4), s. 1–7. doi: 10.1097/TXD.0000000000001142. Fulltekst i vitenarkiv Vis sammendrag

  Background. Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach target blood pressure (BP) ≤130/80 mm Hg. The aim of this study was to identify the determinants of failure to achieve BP control. Methods. In conjunction with the 2018 annual data reporting, additional questions were added for recipients with BP >130/80 mm Hg (treating physician´s target BP for each patient, reasons for not achieving target, method of measurement). Results. Annual forms were received from 98% (3407 of 3486) of KTx recipients, with 1787 (52%) reporting a BP >130/80 mm Hg (“above-target” group). These recipients were older, mostly male, with higher body mass index and serum creatinine levels (P < 0.05) compared with patients with controlled hypertension (“on-target” group). Valid survey answers were available for 84% of the “above-target” group (Survresp) with no significant demographic differences versus nonresponders (Survnonresp). Among Survresp, 32% were under antihypertensive dose titration, whereas dose-limiting side effects were reported in 7%. Target BP was confirmed to 130/80 mm Hg for 60% of Survresp. In recipients for whom the treating physician set target BP >130/80 mm Hg, 51% did not reach these individual targets. The number of antihypertensive drugs was significantly higher in the “above-target” group versus “on-target” group (mean 2.1 ± 1.2 versus 1.8 ± 1.3) and 36% versus 25% used ≥3 antihypertensive drugs (P < 0.05). Automatic attended BP measurement was utilized by 51%. Conclusions. In KTx recipients, a higher BP target achievement seems possible, potentially in the range of 75%-80%.

• Bergan, Stein; Brunet, Mercé; Hesselink, Dennis A.; Johnson-Davis, Kamisha L; Kunicki, Pawel K & Lemaitre, Florian [Vis alle 38 forfattere av denne artikkelen] (2021). Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic Drug Monitoring. ISSN 0163-4356. 43(2), s. 150–200. doi: 10.1097/FTD.0000000000000871.
• Nordheim, Espen; Lindahl, Jørn Petter Hanto; Carlsen, Rasmus Kirkeskov; Åsberg, Anders; Birkeland, Kåre I. & Horneland, Rune [Vis alle 9 forfattere av denne artikkelen] (2021). Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach. Endocrine Connections. ISSN 2049-3614. 10(2), s. 230–239. doi: 10.1530/EC-20-0519. Fulltekst i vitenarkiv
• Kramer, Anneke; Boenink, Rianne; Stel, Vianda S.; de Pablos, Carmen Santiuste; Tomovic, Filip & Golan, Eliezer [Vis alle 46 forfattere av denne artikkelen] (2021). The ERA-EDTA Registry Annual Report 2018: A summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 14(1), s. 107–123. doi: 10.1093/ckj/sfaa271.
• Hilbrands, Luuk B.; Duivenvoorden, Raphal; Vart, Priya; Franssen, Casper F.M.; Hemmelder, Marc H. & Jager, Kitty J. [Vis alle 188 forfattere av denne artikkelen] (2020). COVID-19-related mortality in kidney transplant and dialysis patients: Results of the ERACODA collaboration. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 35(11), s. 1973–1983. doi: 10.1093/ndt/gfaa261.
• Pippias, Maria; Jager, Kitty J; Åsberg, Anders; Berger, Stefan P; Finne, Patrik & Heaf, James G. [Vis alle 11 forfattere av denne artikkelen] (2020). Young deceased donor kidneys show a survival benefit over older donor kidneys in transplant recipients aged 20–50 years: a study by the ERA–EDTA Registry . Nephrology, Dialysis and Transplantation. ISSN 0931-0509. doi: 10.1093/ndt/gfy268.
• Bjerre, Anna Kristina; Mjøen, Geir; Line, Pål Dag; Naper, Christian; Reisæter, Anna Varberg & Åsberg, Anders (2020). Five decades with grandparent donors: The Norwegian strategy and experience. Pediatric Transplantation. ISSN 1397-3142. 24(6). doi: 10.1111/petr.13751. Fulltekst i vitenarkiv
• Skauby, Ragnhild Kristine Heier; Gustavsen, Marte Theie; Andersen, Anders Mikal; Bjerre, Anna Kristina; Åsberg, Anders & Midtvedt, Karsten [Vis alle 8 forfattere av denne artikkelen] (2020). Prednisolone and Prednisone Pharmacokinetics in Adult Renal Transplant Recipients. Therapeutic Drug Monitoring. ISSN 0163-4356. 43(2), s. 247–255. doi: 10.1097/FTD.0000000000000835.
• Gustavsen, Marte Theie; Midtvedt, Karsten; Robertsen, Ida; Woillard, Jean-Baptiste; Debord, Jean & Klaasen, Rolf [Vis alle 9 forfattere av denne artikkelen] (2020). Fasting Status and Circadian Variation Must be Considered When Performing AUC-based Therapeutic Drug Monitoring of Tacrolimus in Renal Transplant Recipients. Clinical and Translational Science (CTS). ISSN 1752-8054. 13(6), s. 1327–1335. doi: 10.1111/cts.12833.
• Thorsteinsdottir, Hjørdis; Christensen, Jacob J.; Holven, Kirsten Bjørklund; Tveiterås, Målfrid; Brun, Henrik & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2020). Cardiovascular risk factors are inversely associated with omega-3 polyunsaturated fatty acid plasma levels in pediatric kidney transplant recipients. Journal of renal nutrition. ISSN 1051-2276. 31(3), s. 278–285. doi: 10.1053/j.jrn.2020.06.002. Vis sammendrag

  Objectives High plasma levels of the omega-3 fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid, and docosapentaenoic acid associates with positive outcomes in adult renal transplant recipients. However, data from pediatric populations are scarce. The aim of the study was to assess the fatty acid profile in a pediatric renal transplantation cohort and to examine the associations between plasma omega-3 fatty acids and cardiovascular disease (CVD) risk factors. Methods In this cross-sectional study comprising 53 children (median age, 12.2 years; 32 boys) with a renal transplant, we assessed the prevalence of CVD risk factors as well as markers of end organ damage: carotid intima-media thickness (cIMT) and left ventricular mass index. The associations between plasma omega-3 fatty acids and CVD risk factors were assessed. Results Twenty-five (47%) patients were preemptively transplanted. Seventy-six percent had dyslipidemia and 51% had hypertension. The mean left ventricular mass index was 40.4 ± 14.3 g/m 2.7, and 14% had left ventricular hypertrophy. The mean cIMT was 0.41 ± 0.04 mm. In a multivariate linear regression, EPA levels were inversely associated to blood pressure (β coeff. = −0.37, P = .007), triglycerides (β coeff. = −0.44, P = .01), and high-density lipoprotein cholesterol (β coeff. = −0.41, P = .01). Conclusion EPA levels are inversely associated with components of the metabolic syndrome, which may provide support for specific dietary advice or supplementation in this patient population. cIMT is less pronounced in our cohort than in comparable cohorts with lower rate of preemptive transplantations. Our results need replication in prospective cohorts.

• Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria & Hjelmesæth, Jøran [Vis alle 15 forfattere av denne artikkelen] (2020). Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes . Journal of Pharmaceutical Sciences. ISSN 0022-3549. 110(1), s. 432–437. doi: 10.1016/j.xphs.2020.10.027. Fulltekst i vitenarkiv
• Wegler, Christine; Garcia, Luna Prieto; Klinting, Signe; Robertsen, Ida; Wisniewski, Jacek R. & Hjelmesæth, Jøran [Vis alle 10 forfattere av denne artikkelen] (2020). Proteomics‐informed prediction of rosuvastatin plasma profiles in patients with a wide range of body weight. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 109(3), s. 762–771. doi: 10.1002/cpt.2056. Fulltekst i vitenarkiv
• Egeland, Erlend Johannessen; Witczak, Bartlomiej J; Zare, Hasse Khiabani; Christensen, Hege Staaland; Åsberg, Anders & Robertsen, Ida (2020). Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End‐Stage Renal Disease. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 108(4), s. 866–873. doi: 10.1002/cpt.1875.
• Kramer, Anneke; Boenink, Rianne; Noordzij, Marlies; Bosdriesz, Jizzo; Stel, Vianda S. & Beltrán, Palma [Vis alle 46 forfattere av denne artikkelen] (2020). The ERA-EDTA Registry Annual Report 2017: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 13(4), s. 693–709. doi: 10.1093/ckj/sfaa048.
• Luis-Lima, Sergio; Mas-Sanmartin, Carolina; Rodríguez-Rodríguez, Ana Elena; Porrini, Esteban; Ortiz, Alberto & Gaspari, Flavio [Vis alle 12 forfattere av denne artikkelen] (2020). A simplified iohexol-based method to measure renal function in sheep models of renal disease. Biology (Basel). ISSN 2079-7737. 9:259(9), s. 1–12. doi: 10.3390/biology9090259.
• Gustavsen, Marte Theie; Midtvedt, Karsten; Vethe, Nils Tore; Robertsen, Ida; Bergan, Stein & Åsberg, Anders (2020). Tacrolimus area under the concentration versus time curve monitoring, using home-based volumetric absorptive capillary microsampling. Therapeutic Drug Monitoring. ISSN 0163-4356. 42(3), s. 407–414. doi: 10.1097/FTD.0000000000000697.
• Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders & Hartmann, Anders [Vis alle 8 forfattere av denne artikkelen] (2020). Endothelial function after pancreas transplantation - A single-center observational study. Clinical Transplantation. ISSN 0902-0063. 34:e13815(3), s. 1–7. doi: 10.1111/ctr.13815. Fulltekst i vitenarkiv
• Wegler, Christine; Ölander, Magnus; Wisniewski, JR; Lundquist, Patrick; Zettl, K & Åsberg, Anders [Vis alle 9 forfattere av denne artikkelen] (2020). Global variability analysis of mRNA and protein concentrations across and within human tissues. NAR Genomics and Bioinformatics. ISSN 2631-9268. 2(1), s. 1–11. doi: 10.1093/nargab/lqz010. Fulltekst i vitenarkiv
• Blom, Kjersti Benedicte; Bergo, Kaja Knudsen; Espe, Emil Knut Stenersen; Rosseland, Vigdis; Grøtta, Ole Jørgen & Mjøen, Geir [Vis alle 17 forfattere av denne artikkelen] (2019). Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study. Blood Pressure. ISSN 0803-7051. 29(2), s. 1–13. doi: 10.1080/08037051.2019.1684817. Fulltekst i vitenarkiv
• Åsberg, Anders; Bjerre, Anna Kristina; Almaas, Runar; Luis-Lima, Sergio; Robertsen, Ida & Salvador, Cathrin Lytomt [Vis alle 10 forfattere av denne artikkelen] (2019). Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance. Kidney International Reports. ISSN 2468-0249. 5(2), s. 189–198. doi: 10.1016/j.ekir.2019.11.012. Fulltekst i vitenarkiv
• Tantiyvarong, Pichaya; Kramer, Anneke; Heaf, James; Finne, Patrik; Åsberg, Anders & Cases, Aleix [Vis alle 10 forfattere av denne artikkelen] (2019). Changes in clinical indicators related to the transition from dialysis to kidney transplantation—data from the ERA–EDTA Registry. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 13(2), s. 188–198. doi: 10.1093/ckj/sfz062.
• Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Wegler, Christine & Angeles, Philip Carlo Soriano [Vis alle 13 forfattere av denne artikkelen] (2019). A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity. Drug Metabolism And Disposition. ISSN 0090-9556. 48(1), s. 8–17. doi: 10.1124/DMD.119.087940.
• Vethe, Nils Tore; Gustavsen, Marte Theie; Midtvedt, Karsten; Lauritsen, May Ellen; Andersen, Anders Mikal & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2019). Tacrolimus Can Be Reliably Measured With Volumetric Absorptive Capillary Microsampling Throughout the Dose Interval in Renal Transplant Recipients. Therapeutic Drug Monitoring. ISSN 0163-4356. 41(5), s. 607–614. doi: 10.1097/FTD.0000000000000655.
• Chandra, Anupam; Midtvedt, Karsten; Åsberg, Anders & Eide, Ivar Anders (2019). Immunosuppression and Reproductive Health After Kidney Transplantation. Transplantation. ISSN 0041-1337. 103(11). doi: 10.1097/TP.0000000000002903.
• Lorent, Marine; Foucher, Yohann; Kerleau, Clarisse; Brouard, Sophie; Baayen, Corine & Lebouter, Sabrina [Vis alle 10 forfattere av denne artikkelen] (2019). The EKiTE network (epidemiology in kidney transplantation - a European validated database): an initiative epidemiological and translational European collaborative research. BMC Nephrology. ISSN 1471-2369. 20:365, s. 1–10. doi: 10.1186/s12882-019-1522-8.
• Kramer, Anneke; Pippias, Maria; Noordzij, Marlies; Stel, Vianda S.; Andrusev, Anton M. & Aparicio-Madre, Manuel I. [Vis alle 41 forfattere av denne artikkelen] (2019). The European Renal Association – European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report 2016: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 12(5), s. 702–720. doi: 10.1093/ckj/sfz011.
• Legendre, Christophe M.; Viebahn, Richard; Crespo, Marta; Dor, Frank; Gustafsson, Bengt & Samuel, Undine [Vis alle 17 forfattere av denne artikkelen] (2019). Beyond Survival in Solid Organ Transplantation: A Summary of Expert Presentations from the Sandoz 6th Standalone Transplantation Meeting, 2018. Transplantation. ISSN 0041-1337. 103(9S), s. S1–S13. doi: 10.1097/TP.0000000000002846.
• Angeles, Philip Carlo Soriano; Robertsen, Ida; Seeberg, Lars Thomas; Krogstad, Veronica; Skattebu, Julie & Sandbu, Rune [Vis alle 8 forfattere av denne artikkelen] (2019). The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review. Obesity Reviews. ISSN 1467-7881. 20(9), s. 1299–1311. doi: 10.1111/obr.12869. Fulltekst i vitenarkiv Vis sammendrag

  Anatomical changes in the gastrointestinal tract and subsequent weight loss may influence drug disposition and thus drug dosing following bariatric surgery. This review systematically examines the effects of bariatric surgery on drug pharmacokinetics, focusing especially on the mechanisms involved in restricting oral bioavailability. Studies with a longitudinal before‐after design investigating the pharmacokinetics of at least one drug were reviewed. The need for dose adjustment following bariatric surgery was examined, as well as the potential for extrapolation to other drugs subjected to coinciding pharmacokinetic mechanisms. A total of 22 original articles and 32 different drugs were assessed. The majority of available data is based on Roux‐en‐Y gastric bypass (RYGBP) (18 of 22 studies), and hence, the overall interpretation is more or less limited to RYGBP. In the case of the majority of studied drugs, an increased absorption rate was observed early after RYGBP. The effect on systemic exposure allows for a low degree of extrapolation, including between drugs subjected to the same major metabolic and transporter pathways. On the basis of current understanding, predicting the pharmacokinetic change for a specific drug following RYGBP is challenging. Close monitoring of each individual drug is therefore recommended in the early postsurgical phase. Future studies should focus on the long‐term effects of bariatric surgery on drug disposition, and they should also aim to disentangle the effects of the surgery itself and the subsequent weight loss.

• Gustavsen, Marte Theie; Midtvedt, Karsten; Lønning, Kjersti; Jacobsen, Thea Johnsen; Reisæter, Anna Varberg & De Geest, Sabina [Vis alle 9 forfattere av denne artikkelen] (2019). Evaluation of tools for annual capture of adherence to immunosuppressive medications after renal transplantation – a single‐centre open prospective trial. Transplant International. ISSN 0934-0874. 32(6), s. 614–625. doi: 10.1111/tri.13412.
• Strøm Halden, Thea Anine; Kvitne, Kine Eide; Midtvedt, Karsten; Rajakumar, Laavanyaah; Robertsen, Ida & Brox, Jan [Vis alle 10 forfattere av denne artikkelen] (2019). Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus. Diabetes Care. ISSN 0149-5992. 42(6), s. 1067–1074. doi: 10.2337/dc19-0093. Fulltekst i vitenarkiv
• Brunet, Mercé; van Gelder, Teun; Åsberg, Anders; Haufroid, Vincent; Hesselink, Dennis A. & Langman, Loralie [Vis alle 37 forfattere av denne artikkelen] (2019). Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report. Therapeutic Drug Monitoring. ISSN 0163-4356. 41(3), s. 261–307. doi: 10.1097/FTD.0000000000000640.
• Skulberg, Arne Kristian; Åsberg, Anders; Zare, Hasse Khiabani; Røstad, Hilde; Tylleskär, Ida & Dale, Ola (2019). Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial. Addiction. ISSN 0965-2140. 114(5), s. 859–867. doi: 10.1111/add.14552. Fulltekst i vitenarkiv
• Thorsen, Inga Strand; Bleskestad, Inger Hjørdis; Åsberg, Anders; Hartmann, Anders; Skadberg, Øyvind & Brede, Cato [Vis alle 10 forfattere av denne artikkelen] (2019). Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study. Clinical Transplantation. ISSN 0902-0063. 33:e13517(5), s. 1–12. doi: 10.1111/ctr.13517. Fulltekst i vitenarkiv
• Eide, Ivar Anders; Rashidi, Forough; Lønning, Kjersti; Oldereid, Nan Birgitte; Reisæter, Anna Varberg & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2019). Contraceptive Choices and Counseling in Norwegian Female Renal Transplant Recipients. Transplantation Proceedings. ISSN 0041-1345. 51(2), s. 470–474. doi: 10.1016/j.transproceed.2019.01.068.
• Klaasen, Rolf; Egeland, Erlend Johannessen; Chan, Wai Joe; Midtvedt, Karsten; Svensson, My Hanna Sofia & Bolstad, Nils [Vis alle 12 forfattere av denne artikkelen] (2019). A Fully Automated Method for the Determination of Serum Belatacept and Its Application in a Pharmacokinetic Investigation in Renal Transplant Recipients. Therapeutic Drug Monitoring. ISSN 0163-4356. 41(1), s. 11–18. doi: 10.1097/FTD.0000000000000580.
• Ussif, Mohammed Al-Amin; Åsberg, Anders; Strøm Halden, Thea Anine; Nordheim, Espen; Hartmann, Anders & Jenssen, Trond Geir (2019). Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation. BMC Nephrology. ISSN 1471-2369. 20:12, s. 1–6. doi: 10.1186/s12882-018-1171-3. Fulltekst i vitenarkiv
• Eide, Ivar Anders; Reinholt, Finn P.; Jenssen, Trond Geir; Hartmann, Anders; Schmidt, Erik B. & Åsberg, Anders [Vis alle 9 forfattere av denne artikkelen] (2019). Effects of marine n-3 fatty acid supplementation in renal transplantation: A randomized controlled trial. American Journal of Transplantation. ISSN 1600-6135. 19, s. 790–800. doi: 10.1111/ajt.15080.
• Krogstad, Veronica; Vethe, Nils Tore; Robertsen, Ida; Hasvold, Grete; Ose, Anne-Marthe Due & Hermann, Monica [Vis alle 12 forfattere av denne artikkelen] (2018). Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies. Therapeutic Drug Monitoring. ISSN 0163-4356. 40(3), s. 292–300. doi: 10.1097/FTD.0000000000000510.
• Egeland, Erlend Johannessen; Reisæter, Anna Varberg; Robertsen, Ida; Midtvedt, Karsten; Strøm, Erik Heyerdahl & Holdaas, Hallvard [Vis alle 8 forfattere av denne artikkelen] (2018). High tacrolimus clearance ? a risk factor for development of interstitial fibrosis and tubular atrophy in the transplanted kidney: a retrospective single-center cohort study. Transplant International. ISSN 0934-0874. 32(3), s. 257–269. doi: 10.1111/tri.13356.
• Chandra, Anupam; Svensson, My Hanna Sofia; Åsberg, Anders; Schmidt, Erik Berg; Bjerve, Kristian S & Jenssen, Trond Geir [Vis alle 9 forfattere av denne artikkelen] (2018). Trans-fatty acids and survival in renal transplantation. Journal of renal nutrition. ISSN 1051-2276. 29(3), s. 169–180. doi: 10.1053/j.jrn.2018.08.003. Fulltekst i vitenarkiv
• Nordheim, Espen; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune & Jenssen, Trond Geir (2018). Preserved insulin secretion and kidney function in recipients with functional pancreas grafts 1 year after transplantation: a single-center prospective observational study. European Journal of Endocrinology (EJE). ISSN 0804-4643. 179(4), s. 251–259. doi: 10.1530/EJE-18-0360. Vis sammendrag

  Objective: Successful simultaneous pancreas and kidney transplantation (SPK) or pancreas transplantation alone (PTA) restores glycemic control. Diabetes and impaired kidney function are common side effects of immunosuppressive therapy. This study addresses glucometabolic parameters and kidney function during the first year. Methods: We examined 67 patients with functioning grafts (SPK n = 30, PTA n = 37) transplanted between September 2011 and November 2016 who underwent repeated oral glucose tolerance tests (OGTTs) 8 and 52 weeks after transplantation. Another 19 patients lost their graft the first year post-transplant and 28 patients did not undergo repeated OGTTs and could not be studied. All patients received ATG induction therapy plus tacrolimus, mycophenolate and prednisolone. Glomerular filtration rate was measured before and 8 and 52 weeks after transplantation by serum clearance methods. Results: From week 8 to 52 after transplantation, mean fasting glucose decreased (SPK: 5.4 ± 0.7 to 5.1 ± 0.8 mmol/L, PTA: 5.4 ± 0.6 to 5.2 ± 0.7 mmol/L; both P < 0.05), and also 120-min post-OGTT glucose (SPK: 6.9 ± 2.9 to 5.7 ± 2.2 mmol/L; P = 0.07, PTA: 6.5 ± 1.7 to 5.7 ± 1.2 mmol/L; P < 0.05). Fasting C-peptide levels also decreased (SPK: 1500 ± 573 to 1078 ± 357 pmol/L, PTA: 1210 ± 487 to 1021 ± 434 pmol/L, both P < 0.005). Measured GFR decreased from enlistment to 8 weeks post transplant in PTA patients (94 ± 22 to 78 ± 19 mL/min/1.73 m2; P < 0.005), but did not deteriorate from week 8 to week 52 (SPK: 55.0 ± 15.1 vs 59.7 ± 11.3 ml/min/1.73 m²; P = 0.19, PTA: 76 ± 19 vs 77 ± 19 mL/min/1.73 m²; P = 0.74). Conclusion: Glycemic control and kidney function remain preserved in recipients with functioning SPK and PTA grafts 1 year after transplantation.

• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Godang, Kristin; Hartmann, Anders & Åsberg, Anders (2018). Arterial stiffness is associated with visceral fat mass in kidney transplanted patients—A nationwide cohort study. Clinical Transplantation. ISSN 0902-0063. 32(8). doi: 10.1111/ctr.13341.
• Ussif, Mohammed Al-Amin; Pihlstrøm, Hege; Pasch, Andreas; Holdaas, Hallvard; Hartmann, Anders & Smerud, Knut Terje [Vis alle 7 forfattere av denne artikkelen] (2018). Paricalcitol supplementation during the first year after kidney transplantation does not affect calcification propensity score. BMC Nephrology. ISSN 1471-2369. 19(1). doi: 10.1186/s12882-018-1000-8. Fulltekst i vitenarkiv
• Thorsteinsdottir, Hjørdis; Diseth, Trond H; Lie, Anine; Tangeraas, Trine; Matthews, Iren & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2018). Small effort, high impact: Focus on physical activity improves oxygen uptake (VO2peak), quality of life, and mental health after pediatric renal transplantation. Pediatric Transplantation. ISSN 1397-3142. 22:e13242(6), s. 1–9. doi: 10.1111/petr.13242. Fulltekst i vitenarkiv
• Foss, Stein; Nordheim, Espen; SØRENSEN, DAG WENDELBO; Syversen, Torgunn Bø; Midtvedt, Karsten & Åsberg, Anders [Vis alle 12 forfattere av denne artikkelen] (2018). First Scandinavian Protocol for Controlled Donation After Circulatory Death Using Normothermic Regional Perfusion. Transplantation direct. ISSN 2373-8731. 4(7). doi: 10.1097/TXD.0000000000000802. Fulltekst i vitenarkiv
• Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg & Chandra, Anupam [Vis alle 10 forfattere av denne artikkelen] (2018). Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation. Journal of renal nutrition. ISSN 1051-2276. 28(5), s. 333–339. doi: 10.1053/j.jrn.2018.02.008. Fulltekst i vitenarkiv
• Robertsen, Ida; Debord, Jean; Åsberg, Anders; Marquet, Pierre & Woillard, Jean-Baptiste (2018). A Limited Sampling Strategy to Estimate Exposure of Everolimus in Whole Blood and Peripheral Blood Mononuclear Cells in Renal Transplant Recipients Using Population Pharmacokinetic Modeling and Bayesian Estimators. Clinical Pharmacokinetics. ISSN 0312-5963. 57(11), s. 1459–1469. doi: 10.1007/s40262-018-0646-5.
• Hjelmesæth, Jøran; Åsberg, Anders; Andersson, Shalini; Sandbu, Rune; Robertsen, Ida & Johnson, Line Kristin [Vis alle 16 forfattere av denne artikkelen] (2018). Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL). BMJ Open. ISSN 2044-6055. 8:e021878(5), s. 1–10. doi: 10.1136/bmjopen-2018-021878. Fulltekst i vitenarkiv
• Heldal, Torbjørn Fossum; Ueland, Thor; Jenssen, Trond Geir; Hartmann, Anders; Reisæter, Anna Varberg & Aukrust, Pål [Vis alle 8 forfattere av denne artikkelen] (2018). Inflammatory and related biomarkers are associated with post-transplant diabetes mellitus in kidney recipients: a retrospective study. Transplant International. ISSN 0934-0874. 31(5), s. 510–519. doi: 10.1111/tri.13116.
• Woillard, Jean-Baptiste; Saint-Marcoux, Franck; Debord, Jean & Åsberg, Anders (2018). Pharmacokinetic models to assist the prescriber in choosing the best tacrolimus dose. Pharmacological Research. ISSN 1043-6618. 130, s. 316–321. doi: 10.1016/j.phrs.2018.02.016.
• Garcia-Carro, Clara; Dörje, Christina; Åsberg, Anders; Midtvedt, Karsten; Scott, Helge & Reinholt, Finn P. [Vis alle 9 forfattere av denne artikkelen] (2018). Kidney allograft subclinical rejection modulates systemic inflammation measured by C-reactive protein at 1 year after transplantation. Clinical Transplantation. ISSN 0902-0063. 32:e13196(3), s. 1–8. doi: 10.1111/ctr.13196.
• Heldal, Kristian; Midtvedt, Karsten; Hartmann, Anders; Reisæter, Anna Varberg; Heldal, Torbjørn Fossum & Bergan, Stein [Vis alle 8 forfattere av denne artikkelen] (2018). Estimated glomerular filtration rate in stable older kidney transplant recipients-are present algorithms valid? A national cross-sectional cohort study. Transplant International. ISSN 0934-0874. 31(6), s. 629–638. doi: 10.1111/tri.13137. Fulltekst i vitenarkiv
• Kramer, Anneke; Pippias, Maria; Noordzij, Marlies; Stel, Vianda S.; Afentakis, Nikolaos & Ambühl, Patrice M. [Vis alle 40 forfattere av denne artikkelen] (2018). The European Renal Association - European Dialysis and Transplantation Association (ERA-EDTA) registry Annual Report 2015: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 11(1), s. 108–122. doi: 10.1093/ckj/sfx149. Fulltekst i vitenarkiv
• Eide, Ivar Anders; Dörje, Christina; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Hammarström, Clara Louise & Scott, Helge [Vis alle 13 forfattere av denne artikkelen] (2018). Development of Kidney Transplant Fibrosis Is Inversely Associated With Plasma Marine Fatty Acid Level. Journal of renal nutrition. ISSN 1051-2276. 28(2), s. 118–124. doi: 10.1053/j.jrn.2017.09.001.
• Lindahl, Jørn Petter Hanto; Horneland, Rune; Nordheim, Espen; Hartmann, Anders; Aandahl, Einar Martin & Grzyb, Krzysztof [Vis alle 10 forfattere av denne artikkelen] (2018). Outcomes in Pancreas Transplantation With Exocrine Drainage Through a Duodenoduodenostomy Versus Duodenojejunostomy. American Journal of Transplantation. ISSN 1600-6135. 18(1), s. 154–162. doi: 10.1111/ajt.14420. Fulltekst i vitenarkiv
• Salvador, Cathrin Lytomt; Hartmann, Anders; Åsberg, Anders; Bergan, Stein; Rowe, Alexander D. & Mørkrid, Lars (2017). Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population. Transplantation direct. ISSN 2373-8731. 3(12). doi: 10.1097/TXD.0000000000000742. Fulltekst i vitenarkiv
• Smerud, Knut Terje; Åsberg, Anders; Kile, Håkon; Pasch, Andreas; Dahle, Dag Olav & Bollerslev, Jens [Vis alle 8 forfattere av denne artikkelen] (2017). A rapid and sustained improvement of calcification propensity score (serum T50) after successful kidney transplantation: Reanalysis of a randomized controlled trial of ibandronate. Clinical Transplantation. ISSN 0902-0063. 31(12). doi: 10.1111/ctr.13131. Fulltekst i vitenarkiv
• Dupont, Laust; Eide, Ivar Anders; Hartmann, Anders; Christensen, Jeppe Hagstrup; Åsberg, Anders & Jenssen, Trond Geir [Vis alle 8 forfattere av denne artikkelen] (2017). Haptoglobin 2-2 Genotype, Patient, and Graft Survival in Renal Transplant Recipients. Progress in transplantation. ISSN 1526-9248. 27(4), s. 386–391. doi: 10.1177/1526924817732020. Fulltekst i vitenarkiv
• Hole, Kristine; Størset, Elisabet; Olastuen, Ane; Haslemo, Tore; Kro, Grete Birkeland & Midtvedt, Karsten [Vis alle 8 forfattere av denne artikkelen] (2017). Recovery of CYP3A Phenotype after Kidney Transplantation. Drug Metabolism And Disposition. ISSN 0090-9556. 45(12), s. 1260–1265. doi: 10.1124/dmd.117.078030.
• Torres, Irina B; Reisæter, Anna Varberg; Moreso, Francesc; Åsberg, Anders; Vidal, Marta & Garcia-Carro, Clara [Vis alle 17 forfattere av denne artikkelen] (2017). Tacrolimus and mycophenolate regimen and subclinical tubulo-interstitial inflammation in low immunological risk renal transplants. Transplant International. ISSN 0934-0874. 30(11), s. 1119–1131. doi: 10.111/tri.13002. Fulltekst i vitenarkiv
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Vis alle 12 forfattere av denne artikkelen] (2017). High tacrolimus clearance is a risk factor for acute rejection in the early phase after renal transplantation. Transplantation. ISSN 0041-1337. 101(8), s. e273–e279. doi: 10.1097/TP.0000000000001796. Fulltekst i vitenarkiv
• Apeland, Terje; Danielsen, Tore; Staal, Eva Marianne; Åsberg, Anders; Thorsen, Inga Strand & Dalsrud, Tom Ole [Vis alle 7 forfattere av denne artikkelen] (2017). Risk factors for exertional rhabdomyolysis with renal stress. BMJ Open sport & exercise medicine. ISSN 2055-7647. 3(1). doi: 10.1136/bmjsem-2017-000241. Fulltekst i vitenarkiv
• Midtvedt, Karsten; Bergan, Stein; Reisæter, Anna Varberg; Vikse, Bjørn Egil & Åsberg, Anders (2017). Exposure to mycophenolate and fatherhood. Transplantation. ISSN 0041-1337. 101(7), s. e214–e217. doi: 10.1097/TP.0000000000001747. Fulltekst i vitenarkiv
• Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen & Åsberg, Anders (2017). The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. British Journal of Clinical Pharmacology. ISSN 0306-5251. 83(7), s. 1457–1465. doi: 10.1111/bcp.13248. Fulltekst i vitenarkiv
• Pippias, Maria; Kramer, Anneke; Noordzij, Marlies; Afentakis, Nikolaos; De La Torre, Ramón Alonso & Ambühl, Patrice M. [Vis alle 58 forfattere av denne artikkelen] (2017). The European Renal Association – European Dialysis and Transplant Association Registry Annual Report 2014: a summary. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 10(2), s. 154–169. doi: 10.1093/ckj/sfw135.
• Rose, J; Emery, Vincent C; Kumar, Deepali; Åsberg, Anders; Hartmann, Anders & Jardine, Alan G. [Vis alle 9 forfattere av denne artikkelen] (2017). Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection. PLoS Pathogens. ISSN 1553-7366. 13(4). doi: 10.1371/journal.ppat.1006299. Fulltekst i vitenarkiv
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Dahle, Dag Olav; Åsberg, Anders & Jenssen, Trond Geir (2017). Associations Between Posttransplantation Diabetes Mellitus and Renal Graft Survival. Transplantation. ISSN 0041-1337. 101(6), s. 1282–1289. doi: 10.1097/TP.0000000000001259. Vis sammendrag

  BACKGROUND: Previous reports indicate that posttransplantation diabetes mellitus (PTDM) is associated with overall renal graft loss, but not death-censored graft loss. METHODS: In this single-center retrospective cohort study of 2749 adult Norwegian renal transplant recipients, transplanted between 1999 and 2011, we estimated overall and death-censored renal graft loss hazard ratios in patients diagnosed with PTDM, impaired glucose tolerance and diabetes before transplantation, using multivariable Cox proportional hazard regression analysis. RESULTS: A total of 893 renal grafts were lost during the study period, either due to recipient death (n = 540) or death-censored graft loss (n = 353). When the observational time started at time of transplantation, diabetes before transplantation was associated with both overall and death-censored graft loss. Pretransplantation diabetes was also associated with a steeper decline in renal graft function, a higher risk of acute rejections and more renal grafts lost due to acute rejection. In patients with a functional renal graft 1 year after transplantation, PTDM was associated with overall graft loss (hazard ratio, 1.46; 95% confidence interval, 1.13-1.88; P < 0.001), but not death-censored graft loss (hazard ratio, 1.25; 95% confidence interval, 0.80-1.96; P = 0.33). We found no significant associations between PTDM and change in renal function during the first 5 years or acute rejection risk during the first year after renal transplantation. Impaired glucose tolerance was not associated with either overall or death-censored graft loss. CONCLUSIONS: The present study confirms previous findings of an increased risk of overall but not death-censored renal graft loss in renal transplant recipients with PTDM. Longstanding diabetes might increase the risk of acute rejections.

• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin & Hartmann, Anders (2017). Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation. Clinical Transplantation. ISSN 0902-0063. 31:e12869(1), s. 1–9. doi: 10.1111/ctr.12869. Fulltekst i vitenarkiv
• Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik & Hartmann, Anders [Vis alle 12 forfattere av denne artikkelen] (2017). Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition. ISSN 1051-2276. 27(3), s. 161–168. doi: 10.1053/j.jrn.2016.09.008. Vis sammendrag

  OBJECTIVE: Marine n-3 polyunsaturated fatty acids (PUFAs) exert potential anti-inflammatory effects and might improve long-term outcomes after renal transplantation. We assessed associations between plasma phospholipid levels of marine n-3 PUFAs and plasma inflammatory biomarkers 10 weeks after renal transplantation. DESIGN: Cross-sectional single-center study. SUBJECTS: A study population of 861 renal transplant recipients transplanted at Oslo University Hospital between 2007 and 2011. METHODS AND MAIN OUTCOME MEASURE: Plasma phospholipid fatty acids were determined by gas chromatography. Marine n-3 PUFA levels were defined as the sum of eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid levels in weight percentage of total plasma phospholipid fatty acids. Plasma inflammatory biomarkers were measured by enzyme immunoassays. We used multivariable linear regression analysis to assess associations between levels of marine n-3 PUFAs and inflammatory biomarkers in plasma. RESULTS: Plasma marine n-3 PUFA levels were inversely associated with plasma levels of proinflammatory biomarkers soluble tumor necrosis factor receptor 1 (standardized regression coefficient -0.11, P < .001) and interleukin-6 (standardized regression coefficient -0.09, P = .01). In contrast, there was no association between plasma levels of marine n-3 PUFAs and the anti-inflammatory mediator interleukin-10. CONCLUSIONS: In this renal transplant cohort, inverse associations between plasma levels of marine n-3 PUFAs and markers of inflammation were demonstrated.

• Smedbråten, Julia; Sagedal, Solbjørg; Åsberg, Anders; Hartmann, Anders; Rollag, Halvor & Mjøen, Geir [Vis alle 10 forfattere av denne artikkelen] (2017). Collectin liver 1 and collectin kidney 1 of the lectin complement pathway are associated with mortality after kidney transplantation. American Journal of Transplantation. ISSN 1600-6135. 17(1), s. 265–271. doi: 10.1111/ajt.13933.
• Garcia-Carro, Clara; Dörje, Christina; Åsberg, Anders; Midtvedt, Karsten; Scott, Helge & Reinholt, Finn P. [Vis alle 9 forfattere av denne artikkelen] (2016). Inflammation in early kidney allograft surveillance biopsieswith and without associated tubulointerstitial chronic damage as a predictor of fibrosis progression & development of de novo donor specific antibodies. Transplantation. ISSN 0041-1337. 101(6), s. 1410–1415. doi: 10.1097/TP.0000000000001216.
• Koopman, Jacob J.E.; Kramer, Anneke; Van Heemst, Diana; Åsberg, Anders; Beuscart, Jean-Baptiste & Buturović-Ponikvar, Jadranka [Vis alle 17 forfattere av denne artikkelen] (2016). Measuring senescence rates of patients with end-stage renal disease while accounting for population heterogeneity: an analysis of data from the ERA-EDTA Registry. Annals of Epidemiology. ISSN 1047-2797. 26(11), s. 773–779. doi: 10.1016/j.annepidem.2016.08.010.
• Nordheim, Espen; Dahle, Dag Olav; Syse, Ingrid Marie; Åsberg, Anders; Reisæter, Anna Varberg & Hartmann, Anders (2016). Resolution of Calciphylaxis After Urgent Kidney Transplantation in 3 Patients With End-Stage Kidney Failure. Transplantation direct. ISSN 2373-8731. 2(11). doi: 10.1097/TXD.0000000000000627.
• SMEDBRÅTEN, Julia; Mjøen, Geir; Hartmann, Anders; Åsberg, Anders; Rollag, Halvor & Mollnes, Tom Eirik [Vis alle 10 forfattere av denne artikkelen] (2016). Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients. BMC Nephrology. ISSN 1471-2369. 17(1). doi: 10.1186/s12882-016-0373-9. Fulltekst i vitenarkiv Vis sammendrag

  Background Higher incidence of malignancy and infectious diseases in kidney transplant recipients is related to immunosuppressive treatment after transplantation and the recipient’s native immune system. The complement system is an essential component of the innate immunity. The aim of the present study was to investigate the association of effector molecules of the lectin complement pathway with graft and patient survival after kidney transplantation. Methods Two mannan-binding lectin (MBL) associated proteases, MASP-2 and MASP-3 (activators of the lectin pathway) and two MBL-associated proteins, MAp44 and MAp19 (inhibitors of the lectin pathway) were measured at the time of transplantation in 382 patients (≥17 years old) transplanted in 2000–2001. The cohort was followed until December 31, 2014. Data on patient and graft survival were obtained from the Norwegian Renal Registry. Cox proportional hazard regression models were performed for survival analyses. Results Low MAp44 level (1st versus 2–4 quartile) was significantly associated with overall mortality; HR 1.52, 95 % CI 1.08–2.14, p = 0.017. In the sub analyses in groups below and above median age (51.7 years), low MAp44 as a predictor of overall mortality was statistically significant only in recipients of ≤51.7 years; HR 2.57, 95 % CI 1.42–4.66, p = 0.002. Furthermore, low MAp44 was associated with mortality due to infectious diseases; HR 2.22, 95 % CI 1.11–4.41, p = 0.023. There was no association between MASP-2, MASP-3 or MAp19 levels and patient mortality. No association between any measured biomarkers and death censored graft loss was found. Conclusions Low MAp44 level at the time of transplantation was associated with increased overall mortality in kidney recipients of median age of 51.7 years or below and with mortality due to infectious diseases in the whole patient cohort after nearly 14-years of follow up after transplantation. No associations between other effector molecules; MASP-2, MASP-3 or MAp19 and recipient mortality were found, as well as no association of any biomarker with death censored graft loss. Keywords Kidney transplantation – Complement – Recipient survival

• Størset, Elisabet; Åsberg, Anders; Hartmann, Anders; Reisæter, Anna Varberg; Holdaas, Hallvard & Skauby, Morten Heier [Vis alle 8 forfattere av denne artikkelen] (2016). Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience. Nephrology. ISSN 1320-5358. 21(10), s. 821–827. doi: 10.1111/nep.12738.
• Størset, Elisabet; Von Düring, Marit Elizabeth; Godang, Kristin; Bergan, Stein; Midtvedt, Karsten & Åsberg, Anders (2016). Prediction of Fat-Free Mass in Kidney Transplant Recipients. Therapeutic Drug Monitoring. ISSN 0163-4356. 38(4), s. 439–446. doi: 10.1097/FTD.0000000000000305.
• Eide, Ivar Anders; Dahle, Dag Olav; Svensson, My Hanna Sofia; Hartmann, Anders; Åsberg, Anders & Bjerve, Kristian S [Vis alle 11 forfattere av denne artikkelen] (2016). Plasma levels of marine n-3 fatty acids and cardiovascular risk markers in renal transplant recipients. European Journal of Clinical Nutrition. ISSN 0954-3007. 70(7), s. 824–830. doi: 10.1038/ejcn.2016.14.
• Strøm Halden, Thea Anine; Egeland, Erlend Johannessen; Åsberg, Anders; Hartmann, Anders; Midtvedt, Karsten & Khiabani, Hassan Zare [Vis alle 11 forfattere av denne artikkelen] (2016). GLP-1 restores altered insulin and glucagon secretion in posttransplantation diabetes. Diabetes Care. ISSN 0149-5992. 39(4), s. 617–624. doi: 10.2337/dc15-2383.
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Åsberg, Anders; Dahle, Dag Olav & Reisæter, Anna Varberg [Vis alle 7 forfattere av denne artikkelen] (2016). Mortality risk in post-transplantation diabetes mellitus based on glucose and HbA1c diagnostic criteria. Transplant International. ISSN 0934-0874. 29(5), s. 568–578. doi: 10.1111/tri.12757.
• Åsberg, Anders; Humar, Atul; Rollag, Halvor; Jardine, Alan G.; Kumar, Deepali & Aukrust, Pål [Vis alle 9 forfattere av denne artikkelen] (2016). Lessons Learned from a Randomized Study of Oral Valganciclovir Versus Parenteral Ganciclovir Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: The VICTOR Trial. Clinical Infectious Diseases. ISSN 1058-4838. 62(9), s. 1154–1160. doi: 10.1093/cid/ciw084.
• Egli, Adrian; Lisboa, Luiz Filipe; O'Shea, Daire; Asberg, Anders; Mueller, Thomas & Emery, Vincent C. [Vis alle 8 forfattere av denne artikkelen] (2016). Complexity of Host Micro-RNA Response to Cytomegalovirus Reactivation after Organ Transplantation. American Journal of Transplantation. ISSN 1600-6135. 16(2), s. 650–660. doi: 10.1111/ajt.13464.
• Jørgensen, Hanne Skou; Eide, Ivar Anders; Hartmann, Anders; Åsberg, Anders; Christensen, Jeppe H. & Schmidt, Erik B. [Vis alle 9 forfattere av denne artikkelen] (2016). Plasma n-3 Polyunsaturated Fatty Acids and Bone Mineral Density in Renal Transplant Recipients. Journal of renal nutrition. ISSN 1051-2276. 26(3), s. 196–203. doi: 10.1053/j.jrn.2015.11.007.
• Dahle, Dag Olav; Åsberg, Anders; Hartmann, Anders; Holdaas, Hallvard; Bachtler, Matthias & Jenssen, Trond Geir [Vis alle 8 forfattere av denne artikkelen] (2016). Serum calcification propensity is a strong and independent determinant of cardiac and all-cause mortality in kidney transplant recipients. American Journal of Transplantation. ISSN 1600-6135. 16(1), s. 204–212. doi: 10.1111/ajt.13443.
• Størset, Elisabet; Åsberg, Anders; Skauby, Morten Heier; Neely, Michael N.; Bergan, Stein & Bremer, Sara [Vis alle 7 forfattere av denne artikkelen] (2015). Improved tacrolimus target concentration achievement using computerized dosing in renal transplant recipients-a prospective, Randomized Study. Transplantation. ISSN 0041-1337. 99(10), s. 2158–2166. doi: 10.1097/TP.0000000000000708.
• Robertsen, Ida; Vethe, Nils Tore; Midtvedt, Karsten; Falck, Pål; Christensen, Hege Staaland & Åsberg, Anders (2015). Closer to the site of action: everolimus concentrations in peripheral blood mononuclear cells correlate well with whole blood concentrations. Therapeutic Drug Monitoring. ISSN 0163-4356. 37(5), s. 675–680. doi: 10.1097/FTD.0000000000000185.
• Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin & Eide, Ivar Anders [Vis alle 8 forfattere av denne artikkelen] (2015). Visceral fat is better related to impaired glucose metabolism than body mass index after kidney transplantation. Transplant International. ISSN 0934-0874. 28(10), s. 1162–1171. doi: 10.1111/tri.12606.
• Dahle, Dag Olav; Eide, Ivar Anders; Åsberg, Anders; Leivestad, Torbjørn; Holdaas, Hallvard & Jenssen, Trond Geir [Vis alle 10 forfattere av denne artikkelen] (2015). Aortic stiffness in a mortality risk calculator for kidney transplant recipients. Transplantation. ISSN 0041-1337. 99(8), s. 1730–1737. doi: 10.1097/TP.0000000000000660.
• Lisboa, Luiz Filipe; Egli, Adrian; O'Shea, Daire; Åsberg, Anders; Hartmann, Anders & Rollag, Halvor [Vis alle 10 forfattere av denne artikkelen] (2015). Hcmv-miR-UL22A-5p: A biomarker in transplantation with broad impact on host gene expression and potential immunological implications. American Journal of Transplantation. ISSN 1600-6135. 15(7), s. 1893–1902. doi: 10.1111/ajt.13222.
• Robertsen, Ida; Åsberg, Anders; Ingerø Olsen, Aleksander; Vethe, Nils Tore; Bremer, Sara & Bergan, Stein [Vis alle 7 forfattere av denne artikkelen] (2015). Use of generic tacrolimus in elderly renal transplant recipients: Precaution is needed. Transplantation. ISSN 0041-1337. 99(3), s. 528–532. doi: 10.1097/TP.0000000000000384.
• Eide, Ivar Anders; Strøm Halden, Thea Anine; Hartmann, Anders; Åsberg, Anders; Dahle, Dag Olav & Reisæter, Anna Varberg [Vis alle 7 forfattere av denne artikkelen] (2015). Limitations of hemoglobin A1c for the diagnosis of posttransplant diabetes mellitus. Transplantation. ISSN 0041-1337. 99(3), s. 629–635. doi: 10.1097/TP.0000000000000376.
• Ueland, Thor; Rollag, Halvor; Hartmann, Anders; Jardine, Alan G.; Humar, Atul & Bignamini, Angelo A [Vis alle 8 forfattere av denne artikkelen] (2015). Increased osteoprotegerin predicts poor virological outcome during anticytomegalovirus theapy in solid organ transplant recipients. Transplantation. ISSN 0041-1337. 99(1), s. 100–105. doi: 10.1097/TP.0000000000000227.
• Størset, Elisabet; Holford, Nick; Hennig, Stefanie; Bergmann, Troels K.; Bergan, Stein & Bremer, Sara [Vis alle 9 forfattere av denne artikkelen] (2014). Improved prediction of tacrolimus concentrations early after kidney transplantation using theory-based pharmacokinetic modelling. British Journal of Clinical Pharmacology. ISSN 0306-5251. 78(3), s. 509–523. doi: 10.1111/bcp.12361.
• Dahle, Dag Olav; Jenssen, Trond Geir; Holdaas, Hallvard; Åsberg, Anders; Soveri, Inga & Holme, Ingar Morten K [Vis alle 12 forfattere av denne artikkelen] (2014). Uric acid and clinical correlates of endothelial function in kidney transplant recipients. Clinical Transplantation. ISSN 0902-0063. 28(10), s. 1167–1176. doi: 10.1111/ctr.12435.
• Lunde, Ingrid; Bremer, Sara; Midtvedt, Karsten; Mohebi, Beata Urbanczyk; Husvegg, Miriam Dahl & Bergan, Stein [Vis alle 8 forfattere av denne artikkelen] (2014). The influence of CYP3A, PPARA and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. European Journal of Clinical Pharmacology. ISSN 0031-6970. 70(6), s. 685–693. doi: 10.1007/s00228-014-1656-3.
• Robertsen, Ida; Åsberg, Anders; Granseth, Tone; Vethe, Nils Tore; Akhlaghi, Fatemeh & Ghareeb, Mwlod [Vis alle 10 forfattere av denne artikkelen] (2014). More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients. Transplantation. ISSN 0041-1337. 97(12), s. 1266–1272. doi: 10.1097/01.TP.0000443225.66960.7e.
• Strøm Halden, Thea Anine; Åsberg, Anders; Vik, Karen; Hartmann, Anders & Jenssen, Trond Geir (2014). Short-term efficacy and safety of sitagliptin treatment in long-term stable renal recipients with new-onset diabetes after transplantation. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 29(4), s. 926–933. doi: 10.1093/ndt/gft536.
• Åsberg, Anders; Bjerre, Anna Kristina & Neely, Michael N. (2014). New algorithm for valganciclovir dosing in pediatric solid organ transplant recipients. Pediatric Transplantation. ISSN 1397-3142. 18(1), s. 103–111. doi: 10.1111/petr.12179.
• Størset, Elisabet; Holford, Nick; Midtvedt, Karsten; Bremer, Sara; Bergan, Stein & Åsberg, Anders (2014). Importance of hematocrit for a tacrolimus target concentration strategy. European Journal of Clinical Pharmacology. ISSN 0031-6970. 70(1), s. 65–77. doi: 10.1007/s00228-013-1584-7.
• Ueland, Thor; Rollag, Halvor; Hartmann, Anders; Jardine, Alan George; Humar, Atul & Michelsen, Annika [Vis alle 9 forfattere av denne artikkelen] (2014). Secreted Wnt antagonists during eradication of cytomegalovirus infection in solid organ transplant recipients. American Journal of Transplantation. ISSN 1600-6135. 14(1), s. 210–215. doi: 10.1111/ajt.12506.
• Jakobsen, Gunn Signe; Skottheim, Ine Blankenberg; Sandbu, Rune; Christensen, Hege Staaland; Røislien, Jo & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2013). Long-term effects of gastric bypass and duodenal switch on systemic exposure of atorvastatin. Surgical Endoscopy. ISSN 0930-2794. 27(6), s. 2094–2101. doi: 10.1007/s00464-012-2716-3.
• Åsberg, Anders; Midtvedt, Karsten; van Guilder, Mike; Størset, Elisabet; Bremer, Sara & Bergan, Stein [Vis alle 9 forfattere av denne artikkelen] (2013). Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation. Transplant International. ISSN 0934-0874. 26(12), s. 1198–1207. doi: 10.1111/tri.12194.
• Darwich, AS; Pade, D; Rowland-Yeo, K; Jamei, M; Åsberg, Anders & Christensen, Hege Staaland [Vis alle 8 forfattere av denne artikkelen] (2013). Application of an in silico physiologically based pharmacokinetic model to simulate oral drug bioavailability of atorvastatin and cyclosporine post bariatric surgery. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 2. doi: 10.1038/psp.2013.23.
• Kotton, Camille N; Kumar, Deepali; Caliendo, Angela M; Åsberg, Anders; Chou, Sunwen & Danziger-Isakov, Lara [Vis alle 7 forfattere av denne artikkelen] (2013). Updated International Consensus Guidelines on the Management of Cytomegalovirus in Solid-Organ Transplantation. Transplantation. ISSN 0041-1337. 96(4), s. 333–360. doi: 10.1097/TP.0b013e31829df29d.
• Stormo, Camilla; Bogsrud, Martin Prøven; Hermann, Monica; Åsberg, Anders; Piehler, Armin & Retterstøl, Kjetil [Vis alle 7 forfattere av denne artikkelen] (2013). UGT1A1*28 is Associated with Decreased Systemic Exposure of Atorvastatin Lactone. Molecular Diagnosis & Therapy. ISSN 1177-1062. 17(4), s. 233–237. doi: 10.1007/s40291-013-0031-x.
• Razonable, Raymund R; Åsberg, Anders; Rollag, Halvor; Duncan, John; Boisvert, Denis & Yao, Joseph D [Vis alle 9 forfattere av denne artikkelen] (2013). Virologic Suppression Measured by a Cytomegalovirus (CMV) DNA Test Calibrated to the World Health Organization International Standard Is Predictive of CMV Disease Resolution in Transplant Recipients. Clinical Infectious Diseases. ISSN 1058-4838. 56(11), s. 1546–1553. doi: 10.1093/cid/cit096.
• Rollag, Halvor; Ueland, Thor; Åsberg, Anders; Hartmann, Anders; Jardine, Alan G. & Humar, Atul [Vis alle 9 forfattere av denne artikkelen] (2013). Characterization of Cytomegalovirus Disease in Solid Organ Transplant Recipients by Markers of Inflammation in Plasma. PLOS ONE. ISSN 1932-6203. 8(4). doi: 10.1371/journal.pone.0060767.
• Robertsen, Ida; Falck, Pål; Andreassen, Arne K.; Næss, Nina Kaajal; Lunder, Niclas & Christensen, Hege Staaland [Vis alle 8 forfattere av denne artikkelen] (2013). Endomyocardial, intralymphocyte and whole blood concentrations of ciclosporin A in heart transplant recipients. Transplantation Research. ISSN 2047-1440. 2(5). doi: 10.1186/2047-1440-2-5.
• Åsberg, Anders; Apeland, Terje; Reisæter, Anna Varberg; Foss, Aksel; Leivestad, Torbjørn & Heldal, Kristian [Vis alle 9 forfattere av denne artikkelen] (2013). Long-term outcomes after cyclosporine or mycophenolate withdrawal in kidney transplantation – results from an aborted trial. Clinical Transplantation. ISSN 0902-0063. 27(2), s. E151–E156. doi: 10.1111/ctr.12076.
• Dahle, Dag Olav; Midtvedt, Karsten; Hartmann, Anders; Jenssen, Trond Geir; Holdaas, Hallvard & Mjøen, Geir [Vis alle 8 forfattere av denne artikkelen] (2013). Endothelial Dysfunction Is Associated With Graft Loss in Renal Transplant Recipients. Transplantation. ISSN 0041-1337. 95(5), s. 733–739. doi: 10.1097/TP.0b013e31827d6312.
• Ulvestad, Maria; Skottheim, Ine Blankenberg; Jakobsen, Gunn Signe; Bremer, Sara; Molden, Espen & Åsberg, Anders [Vis alle 10 forfattere av denne artikkelen] (2013). Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 93(3), s. 275–282. doi: 10.1038/clpt.2012.261.
• Rollag, Halvor; Åsberg, Anders; Ueland, Thor; Hartmann, Anders; Jardine, Alan & Humar, Atul [Vis alle 9 forfattere av denne artikkelen] (2012). Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: Markers of Inflammation as Predictors of Outcome. Transplantation. ISSN 0041-1337. 94(10), s. 1060–1065. doi: 10.1097/TP.0b013e31826c39de.
• Smerud, Knut Terje; Dolgos, Szilviszter; Olsen, IC; Åsberg, Anders; Sagedal, Solbjørg & Reisæter, Anna Varberg [Vis alle 12 forfattere av denne artikkelen] (2012). A 1-Year Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Ibandronate on Bone Loss Following Renal Transplantation. American Journal of Transplantation. ISSN 1600-6135. 12(12), s. 3316–3325. doi: 10.1111/j.1600-6143.2012.04233.x.
• Ulvestad, Maria; Darnell, Malin; Molden, Espen; Ellis, Ewa; Åsberg, Anders & Andersson, Tommy B (2012). Evaluation of Organic Anion-Transporting Polypeptide 1B1 and CYP3A4 Activities in Primary Human Hepatocytes and HepaRG Cells Cultured in a Dynamic Three-Dimensional Bioreactor System. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 343(1), s. 145–156. doi: 10.1124/jpet.112.195750.
• Loftheim, Håvard; Midtvedt, Karsten; Hartmann, Anders; Reisæter, Anna Varberg; Falck, Pål & Holdaas, Hallvard [Vis alle 9 forfattere av denne artikkelen] (2012). Urinary proteomic shotgun approach for identification of potential acute rejection biomarkers in renal transplant recipients. Transplantation Research. ISSN 2047-1440. 1(9). doi: 10.1186/2047-1440-1-9.
• Holdaas, Hallvard; Midtvedt, Karsten & Åsberg, Anders (2012). A drug safety evaluation of everolimus in kidney transplantation. Expert Opinion on Drug Safety. ISSN 1474-0338. 11(6), s. 1013–1022. doi: 10.1517/14740338.2012.722993.
• Emery, Vincent C; Manuel, Oriol; Åsberg, Anders; Pang, Xiaoli; Kumar, Deepali & Hartmann, Anders [Vis alle 12 forfattere av denne artikkelen] (2012). Differential decay kinetics of human cytomegalovirus glycoprotein B genotypes following antiviral chemotherapy. Journal of Clinical Virology. ISSN 1386-6532. 54(1), s. 56–60. doi: 10.1016/j.jcv.2012.01.015.
• Lisboa, L; Tong, Y; Kumar, Deepali; Pang, Xiaoli; Åsberg, Anders & Hartmann, Anders [Vis alle 10 forfattere av denne artikkelen] (2012). Analysis and clinical correlation of genetic variation in cytomegalovirus. Transplant Infectious Disease. ISSN 1398-2273. 14(2), s. 132–140. doi: 10.1111/j.1399-3062.2011.00685.x.
• Amundsen, Rune; Åsberg, Anders; Ohm, Ingrid Kristine & Christensen, Hege Staaland (2012). Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. Drug Metabolism And Disposition. ISSN 0090-9556. 40(4), s. 655–661. doi: 10.1124/dmd.111.043018.
• Akhlaghi, Fatemeh; Dostalek, Miroslav; Falck, Pål; Mendonza, Anisha E.; Amundsen, Rune & Gohh, Reginald Y. [Vis alle 7 forfattere av denne artikkelen] (2012). The Concentration of Cyclosporine Metabolites Is Significantly Lower in Kidney Transplant Recipients With Diabetes Mellitus. Therapeutic Drug Monitoring. ISSN 0163-4356. 34(1), s. 38–45. doi: 10.1097/FTD.0b013e318241ac71.
• Midtvedt, Karsten; Jenssen, Trond Geir; Hartmann, Anders; Vethe, Nils Tore; Bergan, Stein & Havnes, Kjerstin [Vis alle 7 forfattere av denne artikkelen] (2011). No change in insulin sensitivity in renal transplant recipients converted from standard to once-daily prolonged release tacrolimus. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 26(11), s. 3767–3772. doi: 10.1093/ndt/gfr153.
• van Gelder, Teun; Åsberg, Anders; Barrou, B; Budde, Klemens; Cattaneo, Dario & Dudley, Chris [Vis alle 20 forfattere av denne artikkelen] (2011). ESOT - Advisory committee recommendations on generic substitution of immunosuppressive drugs. Transplant International. ISSN 0934-0874. 24(12), s. 1135–1141.
• Vethe, Nils Tore; Midtvedt, Karsten; Åsberg, Anders; Amundsen, Rune & Bergan, Stein (2011). Legemiddelinteraksjoner og immunsuppresjon hos organtransplanterte. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 131(20), s. 2000–2003. doi: 10.4045/tidsskr.11.0138.
• Ulvestad, Maria; Björquist, Petter; Molden, Espen; Åsberg, Anders & Andersson, Tommy B (2011). OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture. Biochemical Pharmacology. ISSN 0006-2952. 82(9), s. 1219–1226. doi: 10.1016/j.bcp.2011.07.076.
• Skottheim, Ine Blankenberg; Bogsrud, Martin Prøven; Hermann, Monica; Retterstøl, Kjetil & Åsberg, Anders (2011). Atorvastatin Metabolite Measurements as a Diagnostic Tool for Statin-Induced Myopathy. Molecular Diagnosis & Therapy. ISSN 1177-1062. 15(4), s. 221–227. doi: 10.1007/bf03256413.
• Myhre, Hans-Arne; Haug Dorenberg, Dagny; Kristiansen, Knut Ivan; Rollag, Halvor; Leivestad, Torbjørn & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2011). Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients. Transplantation. ISSN 0041-1337. 92(2), s. 217–223. doi: 10.1097/TP.0b013e31821fad25.
• Lisboa, L; Åsberg, Anders; Kumar, Deepali; Pang, Xiaoli; Hartmann, Anders & Preiksaitis, Jutta K [Vis alle 10 forfattere av denne artikkelen] (2011). The Clinical Utility of Whole Blood Versus Plasma Cytomegalovirus Viral Load Assays for Monitoring Therapeutic Response. Transplantation. ISSN 0041-1337. 91(2), s. 231–236. doi: 10.1097/TP.0b013e3181ff8719.
• Loftheim, Håvard; Åsberg, Anders & Reubsaet, Jan Leo (2010). Accelerated O-18-labeling in urinary proteomics. Journal of Chromatography A. ISSN 0021-9673. 1217(52), s. 8241–8248. doi: 10.1016/j.chroma.2010.10.119.
• Åsberg, Anders & Bergan, Stein (2010). Kliniske studier på organtransplanterte pasienter - eksempler på utprøverinitiert forskning. Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 118(12), s. 20–23.
• Ellesat, Kathrin; Tollefsen, Knut-Erik; Åsberg, Anders; Thomas, Kevin V & Hylland, Ketil (2010). Cytotoxicity of atorvastatin and simvastatin on primary rainbow trout (Oncorhynchus mykiss) hepatocytes. Toxicology in Vitro. ISSN 0887-2333. 24(6), s. 1610–1618. doi: 10.1016/j.tiv.2010.06.006.
• Skottheim, Ine Blankenberg; Bogsrud, Martin Prøven & Åsberg, Anders (2010). Muskelbivirkninger av statiner : - hva vet vi om mekanismer og hvordan diagnostiseres de? Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 118(7/8), s. 22–25.
• Kotton, Camille N; Kumar, Deepali; Caliendo, Angela M; Åsberg, Anders; Chou, Sunwen & Snydman, David R [Vis alle 8 forfattere av denne artikkelen] (2010). International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation. Transplantation. ISSN 0041-1337. 89(7), s. 779–795. doi: 10.1097/TP.0b013e3181cee42f.
• Åsberg, Anders; Jardine, AG; Bignamini, Angelo A; Rollag, Halvor; Pescovitz, Mark D & Gahlemann, Christoph C [Vis alle 8 forfattere av denne artikkelen] (2010). Effects of the Intensity of Immunosuppressive Therapy on Outcome of Treatment for CMV Disease in Organ Transplant Recipients. American Journal of Transplantation. ISSN 1600-6135. 10(8), s. 1881–1888. doi: 10.1111/j.1600-6143.2010.03114.x.
• Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, Behnaz & Åsberg, Anders (2010). Cyclosporine A, but Not Tacrolimus, Shows Relevant Inhibition of Organic Anion-Transporting Protein 1B1-Mediated Transport of Atorvastatin. Drug Metabolism And Disposition. ISSN 0090-9556. 38(9), s. 1499–1504. doi: 10.1124/dmd.110.032268.
• Åsberg, Anders (2010). Legemiddeldosering ved nedsatt nyrefunksjon. Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 118(4), s. 22–24.
• Narwal, Rajesh; Akhlaghi, Fatemeh; Åsberg, Anders; Hermann, Monica & Rosenbaum, SE (2010). Development of a Population Pharmacokinetic Model for Atorvastatin Acid and Its Lactone Metabolite. Clinical Pharmacokinetics. ISSN 0312-5963. 49(10), s. 693–702.
• Skottheim, IB; Jakobsen, Gunn Signe; Stormark, Kjartan; Christensen, H; Hjelmesæth, Jøran & Jenssen, Trond Geir [Vis alle 8 forfattere av denne artikkelen] (2010). Significant Increase in Systemic Exposure of Atorvastatin After Biliopancreatic Diversion With Duodenal Switch. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 87(6), s. 699–705. doi: 10.1038/clpt.2010.32.
• Åsberg, Anders; Falck, Pål; Undset, Liv H.; Dörje, Christina; Holdaas, Hallvard & Hartmann, Anders [Vis alle 7 forfattere av denne artikkelen] (2010). Computer-assisted cyclosporine dosing performes better than traditional dosing in renal transplant recipients: Results of a pilot study. Therapeutic Drug Monitoring. ISSN 0163-4356. 32(2), s. 152–158.
• Loftheim, Håvard; Nguyen, Thien; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2010). 2-D hydrophilic interaction liquid chromatography-RP separation in urinary proteomics - Minimizing variability through improved downstream workflow compatibility. Journal of Separation Science. ISSN 1615-9306. 33(6-7), s. 864–872. doi: 10.1002/jssc.200900554.
• Humar, Atul; Åsberg, Anders; Kumar, Deepali; Hartmann, Anders; Moussa, George & Jardine, Alan [Vis alle 10 forfattere av denne artikkelen] (2009). An assessment of herpesvirus co-infections in patients with CMV disease: Correlation with clinical and virological outcomes. American Journal of Transplantation. ISSN 1600-6135. 9(2), s. 374–381. doi: 10.1111/j.1600-6143.2008.02501.x.
• Falck, Pål; Fiane, Arnt E; Geiran, Odd & Åsberg, Anders (2009). Individual differences in cyclosporine A pharmacokinetics and its association with acute renal function following heart transplantation. The Open Transplantation Journal. ISSN 1874-4184. 3, s. 9–13. doi: 10.2174/1874418400903010009.
• Åsberg, Anders; Humar, Atul; Jardine, Alan; Rollag, Halvor; Pescovitz, Mark D & Mouas, Houria [Vis alle 11 forfattere av denne artikkelen] (2009). Long-Term Outcomes of CMV Disease Treatment with Valganciclovir Versus IV Ganciclovir in Solid Organ Transplant Recipients. American Journal of Transplantation. ISSN 1600-6135. 9(5), s. 1205–1213. doi: 10.1111/j.1600-6143.2009.02617.x.
• Amundsen, Rune; Åsberg, Anders; Robertsen, Ida; Vethe, Nils Tore; Bergan, Stein & Hartmann, Anders [Vis alle 7 forfattere av denne artikkelen] (2009). Rimonabant Affects Cyclosporine A, but Not Tacrolimus Pharmacokinetics in Renal Transplant Recipients. Transplantation. ISSN 0041-1337. 87(8), s. 1221–1224.
• Åsberg, Anders; Midtvedt, Karsten; Voytovich, Monica Hagen; Line, Pål Dag; Narverud, Janicke & Reisæter, Anna Varberg [Vis alle 9 forfattere av denne artikkelen] (2009). Calcineurin inhibitor effects on glucose metabolism and endothelial function following renal transplantation. Clinical Transplantation. ISSN 0902-0063. 23(4), s. 511–518. doi: 10.1111/j.1399-0012.2009.00962.x.
• Høyem, Sverre; Bruheim, Skjalg; Mælandsmo, Gunhild M; Standal, Marius; Olberg, Dag Erlend & Brudeli, Bjarne [Vis alle 9 forfattere av denne artikkelen] (2009). Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats. European Journal of Medicinal Chemistry. ISSN 0223-5234. 44(10), s. 3874–3879. doi: 10.1016/j.ejmech.2009.04.008.
• Skottheim, IB; Stormark, KM; Stormark, Kjartan; Christensen, H; Jakobsen, GS & Hjelmesæth, Jøran [Vis alle 11 forfattere av denne artikkelen] (2009). Significantly Altered Systemic Exposure to Atorvastatin Acid Following Gastric Bypass Surgery in Morbidly Obese Patients. Clinical Pharmacology and Therapeutics. ISSN 0009-9236. 86(3), s. 311–318. doi: 10.1038/clpt.2009.82.
• Falck, Pål; Midtvedt, Karsten; van Le, Truc Thanh; Storehagen, Live; Holdaas, Hallvard & Hartmann, Anders [Vis alle 7 forfattere av denne artikkelen] (2009). A population pharmacokientic model of ciclosporin applicable for assisting dose management of kidney transplant recipients. Clinical Pharmacokinetics. ISSN 0312-5963. 48(9), s. 615–623. doi: 10.2165/11313380-000000000-00000.
• Boivin, Guy; Goyette, N; Rollag, Halvor; Jardine, Alan; Pescovitz, Mark D & Åsberg, Anders [Vis alle 9 forfattere av denne artikkelen] (2009). Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir. Antiviral Therapy. ISSN 1359-6535. 14(5), s. 697–704.
• Manuel, Oriol; Åsberg, Anders; Pang, Xiaoli; Rollag, Halvor; Emery, Vincent C & Preiksaitis, Jutta K [Vis alle 12 forfattere av denne artikkelen] (2009). Impact of genetic polymorphisms in cytomegalovirus glycoprotein B on outcomes in solid-organ transplant recipients with cytomegalovirus disease. Clinical Infectious Diseases. ISSN 1058-4838. 49(8), s. 1160–1166. doi: 10.1086/605633.
• Høyem, Sverre; Bruheim, Skjalg; Mælandsmo, Gunhild; Standal, Marius; Olberg, Dag Erlend & Brudeli, Bjarne [Vis alle 9 forfattere av denne artikkelen] (2009). Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats. European Journal of Medicinal Chemistry. ISSN 0223-5234. 44, s. 3874–3879.
• Loftheim, Håvard; Nguyen, Thien Duc; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2009). 2-D hydrophilic interaction liquid chromatography-RP separation in urinary proteomics - Minimizing variability through improved downstream workflow compatibility. Journal of Separation Science. ISSN 1615-9306. 32, s. 1–9.
• Falck, Pål; Åsberg, Anders; Guldseth, Heidi; Bremer, Sara; Akhlaghi, Fatemeh & Reubsaet, Jan Leo [Vis alle 9 forfattere av denne artikkelen] (2008). Declining intracellular T-lymphocyte concentration of cyclosporine a precedes acute rejection in kidney transplant recipients. Transplantation. ISSN 0041-1337. 85(2), s. 179–184. doi: 10.1097/TP.0b013e31815feede.
• Storehagen, Live; Falck, Pål & Åsberg, Anders (2008). Ciklosporin A - utvikling av en farmakokinetisk populasjonsmodell. Norsk Farmaceutisk Tidsskrift. ISSN 0029-1935. 116(3), s. 22–23.
• Falck, Pål; Åsberg, Anders; Byberg, Karen-Therese; Bremer, Sara; Bergan, Stein & Reubsaet, Jan Leo [Vis alle 7 forfattere av denne artikkelen] (2008). Reduced Elimination of Cyclosporine A in Elderly (&gt; 65 Years) Kidney Transplant Recipients. Transplantation. ISSN 0041-1337. 86(10), s. 1379–1383. doi: 10.1097/TP.0b013e31818aa4b6.
• Falck, Pål; Vethe, Nils Tore; Åsberg, Anders; Midtvedt, Karsten; Bergan, Stein & Reubsaet, Jan Leo [Vis alle 7 forfattere av denne artikkelen] (2008). Cinacalcet's effect on the pharmacokinetics of tacrolimus, cyclosporine and mycophenolate in renal transplant recipients. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 23, s. 1048–1053. doi: 10.1093/ndt/gfm632.
• Skottheim, Ine Blankenberg; Gedde-Dahl, Ane; Hejazifar, Solmaz; Hoel, Kjersti; Åsberg, Anders & Åsberg, Anders (2008). Statin induced myotoxicity: The lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. European Journal of Pharmaceutical Sciences. ISSN 0928-0987. 33, s. 317–325. doi: 10.1016/j.ejps.2007.12.009.
• Christensen, Hege Staaland & Åsberg, Anders (2008). Interaksjon mellom næringsmidler og legemidler. Norsk tidsskrift for ernæring (NTFE). ISSN 1503-5034. s. 16–21.

Se alle arbeider i Cristin

• Gripheim, Janne Marlene; Åsberg, Anders; Hagness, Morten; Heldal, Kristian & Midtvedt, Karsten (2023). Nyretransplantasjon – en pågående suksesshistorie. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(11). doi: 10.4045/tidsskr.23.0383.
• Graue, Marit; Haugstvedt, Anne; Hermann, Monica; Søfteland, Eirik; Igland, Jannicke & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2023). Hypoglykemi påvist med CGM hos eldre.
• Tran, Trung; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa & Kolderup, Heidi Anette [Vis alle 40 forfattere av denne artikkelen] (2023). Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants (npj Vaccines, (2022), 7, 1, (174), 10.1038/s41541-022-00586-7). npj Vaccines. ISSN 2059-0105. 8(1). doi: 10.1038/s41541-023-00600-6.
• Storås, Andrea; Riegler, Michael Alexander; Halvorsen, Pål; Åsberg, Anders & Strumke, Inga (2022). Predicting drug exposure in kidney transplanted patients using machine learning.
• Midtvedt, Karsten; Vaage, John T.; Heldal, Kristian; Munthe, Ludvig Andre; Lund-Johansen, Fridtjof & Åsberg, Anders (2022). Fourth dose of the SARS-CoV-2 vaccine in kidney transplant recipients with previously impaired humoral antibody response. American Journal of Transplantation. ISSN 1600-6135. doi: 10.1111/ajt.17091.
• Helanterä, Ilkka; Snyder, Jon; Åsberg, Anders; Cruzado, Josep María; Bell, Samira & Legendre, Christophe [Vis alle 13 forfattere av denne artikkelen] (2022). Demonstrating Benefit-Risk Profiles of Novel Therapeutic Strategies in Kidney Transplantation: Opportunities and Challenges of Real-World Evidence. Transplant International. ISSN 0934-0874. 35. doi: 10.3389/ti.2022.10329. Fulltekst i vitenarkiv
• Boenink, Rianne; Astley, Megan E; Huijben, Jilske A; Stel, Vianda S.; Kerschbaum, Julia & Ots-Rosenberg, Mai [Vis alle 41 forfattere av denne artikkelen] (2022). The ERA Registry Annual Report 2019: Summary and age comparisons. Clinical Kidney Journal (CKJ). ISSN 2048-8505. 15(3), s. 452–472. doi: 10.1093/ckj/sfab273.
• Midtvedt, Karsten; Onsøien, Mari Olsen & Åsberg, Anders (2021). Posttransplant Hypertension Matters! Transplantation. ISSN 0041-1337. 10(105), s. e150–e150. doi: 10.1097/TP.0000000000003831.
• Midtvedt, Karsten; Tran, Trung; Parker, Krystina; Marti, Hans Peter; Stenehjem, Aud Eldrid & Gøransson, Lasse Gunnar [Vis alle 12 forfattere av denne artikkelen] (2021). Low Immunization Rate in Kidney Transplant Recipients Also After Dose 2 of the BNT162b2 Vaccine: Continue to Keep Your Guard up! Transplantation. ISSN 0041-1337. 105(8), s. E80–E81. doi: 10.1097/TP.0000000000003856. Fulltekst i vitenarkiv
• Robertsen, Ida; Åsberg, Anders; Jenssen, Trond Geir; Gence, Berfin; Vethe, Nils Tore & Midtvedt, Karsten [Vis alle 8 forfattere av denne artikkelen] (2021). Increased systemic exposure of once-daily tacrolimus in renal transplant recipients on marine omega-3 fatty acid supplementation. Transplant International. ISSN 0934-0874. doi: 10.1111/tri.13917.
• Åsberg, Anders; Bergan, Stein; Bjørkto, Magnus; Mjøen, Geir; Reisæter, Anna Varberg & Robertsen, Ida [Vis alle 7 forfattere av denne artikkelen] (2020). Severe mycophenolate intoxication in a solid organ transplant recipient - No intervention actually needed. Transplantation direct. ISSN 2373-8731. 6:e609, s. 1–4. doi: 10.1097/TXD.0000000000001058.
• Chandra, Anupam; Midtvedt, Karsten; Åsberg, Anders & Eide, Ivar Anders (2020). The Authors’ Reply: Placental Pathology in Pregnancies After Kidney Transplantation. Transplantation. ISSN 0041-1337. 104(7), s. e216–e216. doi: 10.1097/TP.0000000000003120.
• Pippias, Maria; Jager, Kitty J.; Åsberg, Anders; Berger, Stefan; Finne, Patrik & Heaf, James G. [Vis alle 10 forfattere av denne artikkelen] (2020). Young deceased donor kidneys show a survival benefit over older donor kidneys in transplant recipients ages 20–50 years: a study by the ERA–EDTA Registry. Nephrology, Dialysis and Transplantation. ISSN 0931-0509. 35(3), s. 534–543. doi: 10.1093/ndt/gfy268.
• Johnson, Line Kristin; Sandbu, Rune; Robertsen, Ida; Åsberg, Anders; Andersson, Tommy & Andersson, Shalini [Vis alle 8 forfattere av denne artikkelen] (2019). Effect of gastric bypass and very-low energy diet on cardiometabolic risk factors. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 15, s. S114–S114. doi: 10.1016/j.soard.2019.08.232.
• Skulberg, Arne Kristian; Åsberg, Anders; Khiabani, Hassan; Røstad, Hilde; Tylleskär, Ida & Dale, Ola (2019). Pharmacokinetics of a novel, approved, 1.4 mg intranasal naloxone formulation for reversal of opioid overdose- a randomised controlled trial.
• Skulberg, Arne Kristian; Åsberg, Anders; Khiabani, Hassan; Røstad, Hilde; Tylleskär, Ida & Dale, Ola (2019). Pharmacokinetics of a novel, approved, 1.4 mg intranasal naloxone formulation for reversal of opioid overdose- a randomised controlled trial. Vis sammendrag

  Intranasal (IN) naloxone is established as treatment for opioid overdose. Anyone likely to witness an overdose should have access to the antidote. This study presents data on a new formulation of naloxone for this use, recently approved in 12 European countries. Open, randomised four-way crossover trial in human volunteers (n=22). One and two doses of IN 1.4 mg naloxone compared to intramuscular (IM) 0.8 mg and intravenous (IV) 0.4 mg naloxone. Quantification of plasma naloxone was performed by liquid chromatography tandem mass spectrometry. Pharmacokinetic non-compartment analyses were used for the main analyses. A non-parametric pharmacokinetic population model was developed for Monte Carlo simulations of different dosing scenarios. AUC0-last for IN 1.4 mg and IM 0.8 mg were 2.62 ±0.94 and 3.09 ±0.64 h*ng/mL, respectively (p=0.33). Cmax was 2.36 ±0.68 ng/mL for IN 1.4 mg, and 3.73 ±3.34 for IM 0.8 mg (p=0.72). Two IN doses showed dose linearity, and achieved a Cmax of 4.18 ±1.53 ng/mL. Tmax was reached after 20.2 ±9.4 min for IN 1.4 mg and 13.6 ±15.4 min for IM (p=0.098). The absolute bioavailability for IN 1.4 mg was 0.49 (±0.24), while the relative IN/IM bioavailability was 0.52 (±0.25). IN 1.4 mg naloxone provides adequate systemic concentrations compared to IM 0.8 mg, without statistical difference on maximum serum concentration, time to maximum serum concentration or area under the curve. Simulations support that it has a place both as peer administered antidote and for titration of treatment by professionals.

• Angeles, Philip Carlo Soriano; Robertsen, Ida; Seeberg, Lars Thomas; Krogstad, Veronica; Sandbu, Rune & Åsberg, Anders [Vis alle 7 forfattere av denne artikkelen] (2019). Reply to letter: “What about drug bioavailability in patients who had bariatric surgery and dependent on immunosuppressives?”. Obesity Reviews. ISSN 1467-7881. 21(2). doi: 10.1111/obr.12954.
• Robertsen, Ida; Woillard, Jean-Baptiste & Åsberg, Anders (2019). Why dose adjust systemic exposure when looking for associations with adverse events in tacrolimus‐treated transplant recipients? British Journal of Clinical Pharmacology. ISSN 0306-5251. 86(12), s. 2535–2535. doi: 10.1111/bcp.13984.
• Egeland, Erlend Johannessen; Størset, Elisabet; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten & Gustavsen, Marte Theie [Vis alle 10 forfattere av denne artikkelen] (2018). The Authors' Reply. Transplantation. ISSN 0041-1337. 102(1), s. e43–e44. doi: 10.1097/TP.0000000000001961.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Vis alle 12 forfattere av denne artikkelen] (2017). High tacrolimus clearance may predict rejection and chronic damage to the transplanted kidney.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Vis alle 12 forfattere av denne artikkelen] (2017). High tacrolimus clearance – a risk factor for acute rejection and fibrosis in the transplanted kidney.
• Egeland, Erlend Johannessen; Robertsen, Ida; Hermann, Monica; Midtvedt, Karsten; Størset, Elisabet & Gustavsen, Marte Theie [Vis alle 12 forfattere av denne artikkelen] (2017). High tacrolimus clearance and acute rejection risk after renal transplantation.
• Åsberg, Anders; Robertsen, Ida & Midtvedt, Karsten (2017). How to report and interpret bioequivalence data in solid organ transplant recipients. Transplantation. ISSN 0041-1337. 101(11), s. e347–e347. doi: 10.1097/TP.0000000000001894.
• Midtvedt, Karsten; Holdaas, Hallvard; Bergan, Stein & Åsberg, Anders (2017). Costimulation Blockade: America First, Canada Second . . . What About Norway? American Journal of Transplantation. ISSN 1600-6135. 17(8), s. 2230–2230. doi: 10.1111/ajt.14351.
• Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen & Åsberg, Anders (2017). Response to: ‘Response to: Bodyweightadjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance’. British Journal of Clinical Pharmacology. ISSN 0306-5251. 83(6), s. 1357–1358. doi: 10.1111/bcp.13276.
• Størset, Elisabet; Hole, Kristine; Midtvedt, Karsten; Bergan, Stein; Molden, Espen & Åsberg, Anders (2017). Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance. British Journal of Clinical Pharmacology. ISSN 0306-5251. 83(6), s. 1350–1352. doi: 10.1111/bcp.13188.
• Ose, Anne M; Krogstad, Veronica; Hasvold, Grete; Robertsen, Ida; Egeland, Erlend Johannessen & Hermann, Monica [Vis alle 9 forfattere av denne artikkelen] (2017). Optimalisering av metode for kvantifisering av CYP3A5 og P_glykoprotein i små nyrebiopsier.
• Egeland, Erlend Johannessen; Klaasen, Rolf; Krogstad, Veronica; Hermann, Monica; Chan, Joe & Åsberg, Anders (2017). Pharmacokinetics of belatacept- a novel immunosuppressive therapeutic protein.
• Vu, Martin; Krogstad, Veronica; Johnson, Line Kristin; Angeles, Philip Carlo S; Hasvold, Grete & Hermann, Monica [Vis alle 13 forfattere av denne artikkelen] (2017). Effect of low calorie diet on the absolute bioavailability of midazolam in patients with severe obesity.
• Midtvedt, Karsten & Åsberg, Anders (2017). Mycophenolate Acid and Balancing the Risk for Male Allograft Recipients. Transplantation. ISSN 0041-1337. 101(1), s. e39–e39. doi: 10.1097/TP.0000000000001509.
• Egeland, Erlend Johannessen; Hermann, Monica; Robertsen, Ida; Midtvedt, Karsten; Hartmann, Anders & Reisæter, Anna Varberg [Vis alle 12 forfattere av denne artikkelen] (2016). High tacrolimus clearance is a risk factor for acute rejection early after renal transplantation.
• Le, Peter Huy Vo; Robertsen, Ida; Åsberg, Anders; Christensen, Hege Staaland & Hermann, Monica (2016). Utvikling av en sensitiv LC-MS/MS-metode for å kvantifisere midazolam og metabolitter i pasienter med sykelig overvekt før og etter gastrisk bypass-operasjon.
• Egeland, Erlend Johannessen; Hermann, Monica; Eide, Ivar Anders & Åsberg, Anders (2016). Høy takrolimus-konsentrasjon hos nyretransplanterte- en risikofaktor for akutt rejeksjon.
• Marquet, Pierre & Åsberg, Anders (2016). Individualizing Transplant Therapy. I Jelliffe, Roger & Neely, Michael N. (Red.), Individualized Drug Therapy for Patients. Academic Press. ISSN 978-0-12-803348-7. s. 255–280.
• Ulvmoen, Anders; Robertsen, Ida; Åsberg, Anders; Christensen, Hege Staaland & Hermann, Monica (2015). Utvikling av en sensitiv LC-MS/MS-metode for å kvantifisere midazolam og metabolitter in vitro og i sykelig overvektige pasienter.
• Ahlsen, Kathrine; Robertsen, Ida; Midtvedt, Karsten; Åsberg, Anders & Christensen, Hege Staaland (2014). Aktivitet av P-glykoprotein i mononukleære celler fra perifert blod.
• Lilleengen, Anniken; Lunde, Ingrid; Sandbu, Rune; Åsberg, Anders & Christensen, Hege Staaland (2014). CYP3A4-aktivitet ex vivo i individuelle humane intestinale mikrosomer.
• Jensen, Ben Andre; Reubsaet, Leon; Christensen, Hege Staaland; Åsberg, Anders & Hermann, Monica (2013). Utvikling av kvantitativ proteomikkmetode for måling av P-glykoprotein i lymfocytter isolert fra pasienter.
• Dahl, Miriam; Lunde, Ingrid; Mohebi, Beata Urbanczyk; Bremer, Sara; Bergan, Stein & Midtvedt, Karsten [Vis alle 10 forfattere av denne artikkelen] (2013). Farmakokinetisk betydning av sekvensvarianter i CYP3A4, POR og PPAR-alpha.
• Robertsen, Ida; Åsberg, Anders; Granseth, Tone; Vethe, Nils Tore; Akhlaghi, Fatemeh & Ghareeb, Mwlod [Vis alle 10 forfattere av denne artikkelen] (2013). ROSUVASTATIN IS A POTENT LIPID-LOWERING STATIN IN RENAL TRANSPLANT RECIPIENTS RECEIVING EVEROLIMUS. Transplant International. ISSN 0934-0874. 26, s. 50–50.
• Åsberg, Anders; Bjerre, Anna Kristina & Neely, Michael (2013). WHAT IS THE RIGHT VALGANCICLOVIR DOSE IN CHILDREN? Transplant International. ISSN 0934-0874. 26, s. 181–181.
• Åsberg, Anders; Midtvedt, Karsten; Guilder, Mikevan; Storset, Elisabet; Bremer, Sara & Bergan, Stein [Vis alle 9 forfattere av denne artikkelen] (2013). MARGINAL ADVANTAGE OF KNOWING PATIENT'S CYP3A5 GENOTYPE FOR TACROLIMUS DOSING. Transplant International. ISSN 0934-0874. 26, s. 198–198.
• Halden, Thea Anine Strøm; Åsberg, Anders; Hartmann, Anders & Jenssen, Trond Geir (2013). THE EFFECT OF SITAGLIPTIN TREATMENT ON HYPERGLYCEMIA AND INSULIN SECRETION AFTER RENAL TRANSPLANTATION. Transplant International. ISSN 0934-0874. 26, s. 175–176.
• Cobb, B.; Boisvert, D.; Lee, S; Baum, P.; Razonable, R. & Caliendo, A. [Vis alle 9 forfattere av denne artikkelen] (2013). Standardization of CMV DNA Viral Load Monitoring. American Journal of Transplantation. ISSN 1600-6135. 13, s. 210–211.
• Smerud, Knut Terje; Dolgos, Szilviszter; Wiik, Lisa; Meland, Nils; Olsen, I. & Åsberg, Anders [Vis alle 12 forfattere av denne artikkelen] (2013). No Clinically Significant Effects of Calcium/ Calcitriol Supplementation on Loss of Bone Mass during the First Year after Renal Transplantation. American Journal of Transplantation. ISSN 1600-6135. 13, s. 208–208.
• Egli, A; Lisboa, L; O'Shea, D; Emery, V; Åsberg, Anders & Hartmann, Anders [Vis alle 8 forfattere av denne artikkelen] (2013). A Complex Host MicroRNA Response to Cytomegalovirus Infection: A Bench to Bedside Analysis. American Journal of Transplantation. ISSN 1600-6135. 13, s. 57–57.
• Midtvedt, Karsten; Loftheim, Håvard; Hartmann, Anders; Reisæter, Anna Varberg; Falck, Pål & Holdaas, Hallvard [Vis alle 9 forfattere av denne artikkelen] (2012). Urinary Proteomic Shotgun Approach for a Noninvasive Diagnosis of Acute Rejection of Renal Allografts. American Journal of Transplantation. ISSN 1600-6135. 12(supp. 3), s. 195–195.
• Emery, Vincent C; Rose, J; Manuel, O; Humar, A; Åsberg, Anders & Neumann, A (2012). A Full Dynamic Model To Explain Declines in Cytomegalovirus (CMV) Load after Ganciclovir Therapy in Patients with CMV Disease. American Journal of Transplantation. ISSN 1600-6135. 12, s. 69–69.
• Hotvedt, Tor Arne; Fleischer, Phillip; Molden, Espen; Åsberg, Anders & Christensen, Hege Staaland (2012). Cytokiners effekt på CYP3A4-mediert metabolisme av midazolam i THLE-celler.
• Robertsen, Ida; Falck, Pål; Næss, Nina Kaajal; Andreassen, Arne K.; Gullestad, Lars & Christensen, Hege Staaland [Vis alle 7 forfattere av denne artikkelen] (2012). Endomyovardial, intralymphocyte and whole blood concentrations of cyclosporine A in heart transplant recipients.
• Razonable, Raymund R; Yao, Joseph; Caliendo, Angela M; Do, Tri; Duncan, John & Humar, Atul [Vis alle 8 forfattere av denne artikkelen] (2012). Virological Suppression as Measured by the WHO International Standard Is Predictive of CMV Disease Resolution in Transplant Recipients. American Journal of Transplantation. ISSN 1600-6135. 12, s. 70–70.
• Smerud, Knut Terje; Dolgos, Szilviszter; Olsen, Inge Christoffer; Åsberg, Anders; Sagedal, Solbjørg & Reisæter, Anna Varberg [Vis alle 10 forfattere av denne artikkelen] (2011). A ONE YEAR PROSPECTIVE, RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF INTRAVENOUS IBANDRONATE ON BONE LOSS FOLLOWING RENAL TRANSPLANTATION. Transplant International. ISSN 0934-0874. 24, s. 40–40.
• Huynh, C; Nordeng, Marit; Skottheim, Ine Blankenberg; Sandbu, Rune; Åsberg, Anders & Christensen, Hege Staaland (2011). Individuell variasjon i P-glykoprotein uttrykk i ulike deler av mage- og tarmsystemet.
• Amundsen, Rune; Åsberg, Anders; Ohm, IK & Christensen, Hege Staaland (2011). Ciklosporin og takrolimus som hemmere av CYP3A4 og CYP3A5.
• Christensen, Hege Staaland; Amundsen, Rune & Åsberg, Anders (2011). Mechanisms involved in the pharmacokinetic interaction between atorvastatin and cyclosporine A.
• Åsberg, Anders; Jardine, AG; Bignamini, AA; Rollag, Halvor; Gahlemann, Christoph C & Humar, A [Vis alle 7 forfattere av denne artikkelen] (2011). Response to Letter About Intensity of Immunosuppressive Therapy on Outcome of Treatment for CMV Disease. American Journal of Transplantation. ISSN 1600-6135. 11(5), s. 1103–1104. doi: 10.1111/j.1600-6143.2011.03500.x.
• Loftheim, Håvard; Midtvedt, Karsten; Falck, Pål; Hartmann, Anders; Reubsaet, Leon & Åsberg, Anders (2011). Urinary Proteomics – A Potential Method for Characterization of Acute Rejection Biomarkers.
• Akhlaghi, F.; Chitnis, S.D.; Ionita, I.; Christians, U. & Åsberg, Anders (2011). Impact of diabetes mellitus on metabolism of immunosuppressive agents: cyclosporin, tacrolimus and prednisone. Therapeutic Drug Monitoring. ISSN 0163-4356. 33(4), s. 533–533.
• Ulvestad, Maria; Molden, Espen; Åsberg, Anders; Björquist, Petter & Andersson, Tommy (2010). Time Dependent Activity of the Uptake Transporter OATP1B1 in Plated Primary Human Hepatocytes. Drug metabolism reviews (Softcover ed.). ISSN 0360-2532. 42, s. 291–291.
• Vist, Solveig; Skottheim, Ine Blankenberg; Sandbu, Rune; Åsberg, Anders & Christensen, Hege Staaland (2010). Uttrykk av CYP3A4 og CYP3A5 i parrede prøver fra GI-traktus og lever fra overvektige personer.
• Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, B & Åsberg, Anders (2010). Cyclosporin A, men ikke takrolimus, hemmer OATP1B1-mediert opptak av atorvastatin.
• Amundsen, Rune; Christensen, Hege Staaland; Zabihyan, Behnaz & Åsberg, Anders (2010). Cyclosporine A, but not tacrolimus, shows relevant inhibition of OATP1B1-mediated transport of atorvastatin.
• Ellesat, Kathrin; Tollefsen, Knut-Erik; Skottheim, Ine Blankenberg; Åsberg, Anders & Hylland, Ketil (2010). Toxicity of statins to rainbow trout (Oncorhynchus mykiss) hepatocytes.
• Åsberg, Anders; Rollag, Halvor & Hartmann, Anders (2010). Valganciclovir for the prevention and treatment of CMV in solid organ transplant recipients. Expert Opinion on Pharmacotherapy. ISSN 1465-6566. 11(7), s. 1159–1166. doi: 10.1517/14656561003742954.
• Åsberg, Anders (2010). CMV treatment guideline updates and future perspectives of the VICTOR trial.
• Loftheim, Håvard; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2010). Accelerated 18O/16O labeling in urinary proteomics.
• Loftheim, Håvard; Åsberg, Anders & Reubsaet, Jan Leo (2010). Rapid Biomarker Discovery in Transplantation by Urinary Proteomics utilizing Accelerated 18O-labeling.
• Åsberg, Anders (2010). Internetmedisin - er det verdt prisen?
• Åsberg, Anders (2010). Utvikling av legemidler – fokus på klinisk utprøving og farmakokinetikk.
• Amundsen, Rune; Åsberg, Anders; Robertsen, Ida; Vethe, Nils Tore; Bergan, Stein & Hartmann, Anders [Vis alle 7 forfattere av denne artikkelen] (2009). Rimonabant Affects Cyclosporine A, but Not Tacrolimus Pharmacokinetics in Renal Transplant Recipients. American Journal of Transplantation. ISSN 1600-6135. 9, s. 394–395.
• Amundsen, Rune; Zabihyan, Behnaz; Christensen, Hege Staaland & Åsberg, Anders (2009). CYCLOSPORINE A, BUT NOT TACROLIMUS, INHIBITS OATP1B1 MEDIATED TRANSPORT OF ATORVASTATIN. Journal of clinical pharmacology. ISSN 0091-2700. 49(9), s. 1112–1112.
• Åsberg, Anders; Undset, LH; Falck, Pål; Dorje, Christina; Holdaas, Hallvard & Hartmann, Anders [Vis alle 7 forfattere av denne artikkelen] (2009). COMPUTER ASSISTED CYCLOSPORINE DOSING IN RENAL TRANSPLANT RECIPIENTS. Transplant International. ISSN 0934-0874. 22, s. 231–232.
• Loftheim, Håvard; Nguyen, Duc Thien; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2009). Possible pitfalls in urinary proteomics: evaluating strengths and weaknesses in the sample pretreatment.
• Loftheim, Håvard; Nguyen, Duc Thien; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2009). Possible pitfalls in urinary proteomics: evaluating strengths and weaknesses in the sample pretreatment.
• Skottheim, Ine Blankenberg; Kjartan, Stormark; Christensen, Hege Staaland; Jacobsen, Gunn Signe; Hjelmesæth, Jøran & Jensen, Trond [Vis alle 9 forfattere av denne artikkelen] (2009). Signifikant endret biotilgjengelighet av atorvastatin etter gastrisk bypass i sykelig overvektige pasienter.
• Ellesat, Kathrin; Tollefsen, Knut-Erik; Åsberg, Anders & Hylland, Ketil (2009). The toxicity of statins to rainbow trout hepatocytes.
• Amundsen, Rune; Åsberg, Anders; Robertsen, Ida; Vethe, Nils Tore; Bergan, Stein & Midtvedt, Karsten (2009). Rimonabant Affects Cyclosporine A, but Not Tacrolimus Pharmacokinetics in Renal Transplant Recipients.
• Amundsen, Rune; Zabihyan, Behnaz; Christensen, Hege Staaland & Åsberg, Anders (2009). CYCLOSPORINE A, BUT NOT TACROLIMUS, INHIBITS OATP1B1 MEDIATED TRANSPORT OF ATORVASTATIN.
• Loftheim, Håvard; Nguyen, Duc Thien; Malerød, Helle; Lundanes, Elsa; Åsberg, Anders & Reubsaet, Jan Leo (2009). Optimization of the Sample Preparation in Urinary Proteomics.
• Humar, Atul; Åsberg, Anders; Hartmann, Anders; Pescovitz, Mark D; Rollag, Halvor & Jardine, AG [Vis alle 7 forfattere av denne artikkelen] (2009). Natural Polymorphisms in CMV Genes and Their Effect on Viral Fitness.
• Lisboa, L; Åsberg, Anders; Hartmann, Anders; Kumar, Deepali; Pescovitz, Mark D & Rollag, Halvor [Vis alle 10 forfattere av denne artikkelen] (2009). Comparison of Highly Sensitive vs. Standard CMV Viral Load Assays for Monitoring Therapeutic Response.
• Åsberg, Anders (2008). Veimaling i piratmedisin. [Avis]. www.nettavisen.no.
• Åsberg, Anders (2008). EPO-Erytropoietin. Sportsklubben Rye.

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