Ute Krengel

Bilde av Ute Krengel
English version of this page
Telefon +47-22855461
Rom VU 74
Brukernavn
Besøksadresse Sem Sælands vei 26 0371 OSLO
Postadresse Postboks 1033 0315 OSLO
Andre tilknytninger Kjemisk institutt

Faglige interesser

Gruppen til Ute Krengel bestemmer molekylstrukturene av proteiner ned til atomær oppløsning. Hovedfokuset er på proteiner av medisinsk interesse, og spesielt på protein-karbohydrat interaksjoner. Protein-karbohydrat interaksjoner er sentrale i mange biologiske prosesser (f.eks. interaksjoner mellom celler, cellulær signalisering og differensiering, og immunrespons).

Å forstå karbohydratenes rolle i disse prosessene, og hvordan de vekselvirker med proteiner er forventet å få avgjørende betydning for utvikling av nye behandlingsformer for mange sykdommer.

Forskningen innebærer et nært samarbeid med andre forskningsgrupper (biokjemikere, molekyl-modellerere, bioinformatikere samt NMR-spektroskopikere og massespektrometrikere), noe som garanterer at strukturstudier av utvalgte forskningsmål kan utføres hånd i hånd med protein "engineering", bindingsstudier, mikrokalorimetri og molekylmodellering.

Undervisning

Aktuelle forskningsmål

Lektiner (karbohydratbindende proteiner) fra bakterier, planter og sopp, toksiner, muciner og antistoff mot kreft.

Utvalgte referanser

Review series: Nature 2007, 446, 999-1051 and Science 2001, 291, 2337-2378.

U. Krengel & A. Imberty (2007), Crystallography and lectin structure database, In: Lectins: Analytical technologies (C. Nilsson, Ed.), Elsevier, pp.15-50.

G. Cordara & U. Krengel (2013). Lectin structure determination by X-ray crystallography – A hands-on approach. In: SPR Carbohydrate Chemistry Vol 39 (A. Rauter, Ed.), RSC, 222-246.

A. van Eerde, E.M. Grahn, H.C. Winter, I.J. Goldstein & U. Krengel (2015). Atomic-resolution structure of the α-galactosyl binding Lyophyllum decastes lectin reveals a new protein family found in both fungi and plants. Glycobiology 25, 492-501.

Å. Holmner, A. Mackenzie & U. Krengel (2010). Hypothesis: Molecular basis of cholera blood-group dependence and implications for a world characterized by climate change. FEBS Lett. 584, 2548-2555.

U. Krengel & P.A. Bousquet (2014). Molecular recognition of gangliosides and their potential for cancer immunotherapies. Front Immunol. 5, 325, 1-11.

D. Burschowsky, A. van Eerde, M. Ökvist, A. Kienhöfer, P. Kast, D. Hilvert & U. Krengel (2014) .Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis. Proc Natl Acad Sci U S A. 111, 17516-21.

U. Krengel & S. Törnroth-Horsefield (2015). Coping with oxidative stress. Science 347, 125-6.

Curriculum vitae

CV (pdf)

Samarbeid

Deltaker i UiO Forskningsnettverk og satsinger

  • MLS
  • GLYCONOR
  • PROTSTRUC
Emneord: Kjemi, Biologisk kjemi, Livsvitenskap - life science

Publikasjoner

  • Cordara, Gabriele; Manna, Dipankar & Krengel, Ute (2017). A family of papain-like fungal chimerolectins with distinct Ca2+-dependent activation mechanism. Biochemistry.  ISSN 1520-4995.  56(35), s 4689- 4700 . doi: 10.1021/acs.biochem.7b00317
  • Hatlem, Daniel; Heggelund, Julie Elisabeth; Burschowsky, Daniel; Krengel, Ute & Kristiansen, Per Eugen (2017). 1H, 13C, 15N backbone assignment of the human heat-labile enterotoxin B-pentamer and chemical shift mapping of neolactotetraose binding. Biomolecular NMR Assignments.  ISSN 1874-2718.  11(1), s 99- 104 . doi: 10.1007/s12104-017-9728-9 Fulltekst i vitenarkiv.
  • Heggelund, Julie Elisabeth; Mackenzie, Alasdair; Martinsen, Tobias; Heim, Joël Benjamin; Cheshev, Pavel; Bernardi, Anna & Krengel, Ute (2017). Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics. Scientific Reports.  ISSN 2045-2322.  7(2326) . doi: 10.1038/s41598-017-02179-0
  • Heggelund, Julie Elisabeth; Varrot, Annabelle; Imberty, Anne & Krengel, Ute (2017). Histo-blood group antigens as mediators of infections. Current opinion in structural biology.  ISSN 0959-440X.  44, s 190- 200 . doi: 10.1016/j.sbi.2017.04.001
  • Manna, Dipankar; Pust, Sascha; Torgersen, Maria Lyngaas; Cordara, Gabriele; Kunzler, Markus; Krengel, Ute & Sandvig, Kirsten (2017). Polyporus squamosus lectin 1a (PSL1a) exhibits cytotoxicity in mammalian cells by disruption of focal adhesions, inhibition of protein synthesis and induction of apoptosis. PLoS ONE.  ISSN 1932-6203.  12(1) . doi: 10.1371/journal.pone.0170716
  • Cordara, Gabriele; Van Eerde, Jan Hendrik; Grahn, Elin; Winter, HC; Goldstein, IJ & Krengel, Ute (2016). An unusual member of the papain superfamily: Mapping the catalytic cleft of the Marasmius oreades agglutinin (MOA) with a caspase inhibitor. PLoS ONE.  ISSN 1932-6203.  11(2) . doi: 10.1371/journal.pone.0149407 Fulltekst i vitenarkiv.
  • Heggelund, Julie Elisabeth; Burschowsky, Daniel; Bjørnestad, Victoria Ariel; Hodnik, Vesna; Anderluh, Gregor & Krengel, Ute (2016). High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. PLoS Pathogens.  ISSN 1553-7366.  12(4), s e1005567 . doi: 10.1371/journal.ppat.1005567 Fulltekst i vitenarkiv.
  • Munack, Steffi; Roderer, Kathrin; Ökvist, Mats; Kamarauskaite, Jurate; Sasso, Severin; Van Eerde, Jan Hendrik; Kast, Peter & Krengel, Ute (2016). Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway. Journal of Molecular Biology.  ISSN 0022-2836.  428(6), s 1237- 1255 . doi: 10.1016/j.jmb.2016.01.001
  • Bousquet, Paula; Sandvik, Joe Alexander; Arntzen, Magnus Øverlie; Jeppesen Edin, Nina F; Christoffersen, Stine; Krengel, Ute; Pettersen, Erik O & Thiede, Bernd (2015). Hypoxia Strongly Affects Mitochondrial Ribosomal Proteins and Translocases, as Shown by Quantitative Proteomics of HeLa Cells. International Journal of Proteomics.  ISSN 2090-2174. . doi: 10.1155/2015/678527
  • Heggelund, Julie Elisabeth; Bjørnestad, Victoria Ariel & Krengel, Ute (2015). Vibrio cholerae and Escherichia coli heat-labile enterotoxins and beyond, In Joseph E Alouf; Daniel Ladant & Michel R Popoff (ed.),  The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition.  Elsevier.  ISBN 978-0-12-800188-2.  Section II, chapter 7.  s 195 - 229 Vis sammendrag
  • Krengel, Ute & Törnroth-Horsefield, Susanna (2015). Coping with oxidative stress - A crystal structure helps to explain how cells detoxify. Science.  ISSN 0036-8075.  347(6218), s 125- 126 . doi: 10.1126/science.aaa3602
  • Van Eerde, Jan Hendrik; Grahn, Elin; Winter, Harry C.; Goldstein, Irwin J. & Krengel, Ute (2015). Atomic-resolution structure of the α-galactosyl binding Lyophyllum decastes lectin reveals a new protein family found in both fungi and plants. Glycobiology.  ISSN 0959-6658.  25(5), s 492- 501 . doi: 10.1093/glycob/cwu136
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2014). Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  111(49), s 17516- 17521 . doi: 10.1073/pnas.1408512111
  • Cordara, Gabriele; Winter, Harry C.; Goldstein, Irwin J.; Krengel, Ute & Sandvig, Kirsten (2014). The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  447(4), s 586- 589 . doi: 10.1016/j.bbrc.2014.04.043
  • Krengel, Ute & Bousquet, Paula (2014). Molecular recognition of gangliosides and their potential for cancer immunotherapies. Frontiers in Immunology.  ISSN 1664-3224.  5:325 . doi: 10.3389/fimmu.2014.00325
  • Vasile, Francesca; Reina, José J.; Potenza, Donatella; Heggelund, Julie Elisabeth; Mackenzie, Alasdair; Krengel, Ute & Bernardi, Anna (2014). Comprehensive analysis of blood group antigen binding to classical and El Tor cholera toxin B-pentamers by NMR. Glycobiology.  ISSN 0959-6658.  24(8), s 766- 778 . doi: 10.1093/glycob/cwu040
  • Gertrudis, Rojas; Amaury, Pupo; Silvia, Gómez; Krengel, Ute & Ernesto, Moreno (2013). Engineering the Binding Site of an Antibody against N-Glycolyl GM3: From Functional Mapping to Novel Anti-ganglioside Specificities. ACS Chemical Biology.  ISSN 1554-8929.  8(2), s 376- 386 . doi: 10.1021/cb3003754
  • Cordara, Gabriele & Krengel, Ute (2012). Structure determination of lectins by x-ray crystallography - a hands-on approach, In A.P. Rauter & T.K. Lindhorst (ed.),  Carbohydrate Chemistry - Chemical and Biological Approaches.  Royal Society of Chemistry.  ISBN 9781849731546.  Volume 39.  s 222 - 246
  • Heggelund, Julie Elisabeth; Haugen, Espen; Lygren, Birgitte; Mackenzie, Alasdair; Roclöv, Åsa Holmner; Vasile, Francesca; Reina, José J.; Bernardi, Anna & Krengel, Ute (2012). Both El Tor and classical cholera toxin bind blood group determinants. Biochemical and Biophysical Research Communications - BBRC.  ISSN 0006-291X.  418(4), s 731- 735 . doi: 10.1016/j.bbrc.2012.01.089
  • Munack, Steffi; Leroux, Vincent; Roderer, Kathrin; Ökvist, Mats; Van Eerde, Jan Hendrik; Gundersen, Lise-Lotte; Krengel, Ute & Kast, Peter (2012). When Inhibitors Do Not Inhibit: Critical Evaluation of Rational Drug Design Targeting Chorismate Mutase from Mycobacterium tuberculosis. Chemistry and Biodiversity.  ISSN 1612-1872.  9(11), s 2507- 2527 . doi: 10.1002/cbdv.201200322 Vis sammendrag
  • Ambort, Daniel; van der Post, Sjoerd; Johansson, Malin E.V.; Mackenzie, Jenny Maria; Thomsson, Elisabeth; Krengel, Ute & Hansson, Gunnar C. (2011). Function of the CysD domain of the gel-forming MUC2 mucin. Biochemical Journal.  ISSN 0264-6021.  436, s 61- 70 . doi: 10.1042/BJ20102066
  • Berger, Christian; Krengel, Ute; Stang, Espen; Moreno, Ernesto & Madshus, Inger Helene (2011). Nimotuzumab and Cetuximab Block Ligand-independent EGF Receptor Signaling Efficiently at Different Concentrations. Journal of immunotherapy (1997).  ISSN 1524-9557.  34(7), s 550- 555 . doi: 10.1097/CJI.0b013e31822a5ca6

Se alle arbeider i Cristin

  • Hatlem, Daniel; Leo, Jack Christoffer; Saragliadis, Athanasios; Krengel, Ute & Linke, Dirk (2017). Bacterial adhesion: Characterization of trimeric autotransporter binding.
  • Heim, Joël Benjamin; Teter, Ken & Krengel, Ute (2017). Molecular interactions of cholera toxin – working with unstable proteins and complexes.
  • Heim, Joël Benjamin; Teter, Ken & Krengel, Ute (2017). Molecular interactions of cholera toxin – working with unstable proteins and complexes.
  • Krengel, Ute (2017). Enzyme Catalysis and Regulation: A Model Enzyme Revisited.
  • Krengel, Ute (2017). Molecular Basis of Blood-Group-Dependent Diseases Like Cholera.
  • Tonjum, Tone; Krengel, Ute & Heggelund, Julie Elisabeth (2017). 5 alternativer til antibiotika.
  • Tveitan, Siri Luise; Heim, Joël Benjamin & Krengel, Ute (2017). Structural Studies on Cholera.
  • Hatlem, Daniel; Kempf, Volkhard A.J.; Krengel, Ute & Linke, Dirk (2016). Bacterial adhesion: Characterization of trimeric autotransporter binding.
  • Heim, Joël Benjamin; Heggelund, Julie Elisabeth & Krengel, Ute (2016). Cholera blood-group dependence and role of secretor status.
  • Heim, Joël Benjamin; Heggelund, Julie Elisabeth & Krengel, Ute (2016). Cholera blood-group dependence and role of secretor status.
  • Heim, Joël Benjamin; Heggelund, Julie Elisabeth & Krengel, Ute (2016). How does blood group secretor status protect from cholera intoxication? – Structure and interaction analysis of carbohydrate binding.
  • Krengel, Ute (2016). Enzyme catalysis and regulation: A model enzyme revisited.
  • Manna, Dipankar; Cordara, Gabriele; Sandvig, Kirsten & Krengel, Ute (2016). I Robot- Biological nanomachines for fungal defense.
  • Manna, Dipankar & Krengel, Ute (2016). Structure-function characterization and cytotoxicity studies of fungal chimerolectins. NBS-nytt.  ISSN 0801-3535.
  • Manna, Dipankar; Krengel, Ute & Johansen, Harald Thidemann (2016). Structure-function characterization and cytotoxicity studies of fungal chimerolectins.
  • Manna, Dipankar; Krengel, Ute & Sandvig, Kirsten (2016). Structure-function characterization and cytotoxicity studies of fungal chimerolections. NBS-nytt.  ISSN 0801-3535.
  • Tveitan, Siri Luise; Heim, Joël Benjamin & Krengel, Ute (2016). Cholera under the Molecular Microscope.
  • Tveitan, Siri Luise; Heim, Joël Benjamin & Krengel, Ute (2016). Cholera under the Molecular Microscope.
  • Bjerregaard-Andersen, Kaare; Rydmark, Marcella Orwick & Krengel, Ute (2015). Structure determination of a bacterial adhesin.
  • Burschowsky, Daniel; Krengel, Ute; Uggerud, Einar & Balcells, David (2015). Quantum chemical modeling of chorismate mutase catalysis.
  • Heggelund, Julie Elisabeth; Krengel, Ute & Prydz, Kristian (2015). Cholera toxin – carbohydrate interaction as the basis for cholera blood-group dependence. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 1644.
  • Krengel, Ute (2015). Cholera Toxin: Functional Consequences of Protein-Carbohydrate Interactions.
  • Krengel, Ute (2015). Hassel Lecturer 2015: Peter Seeberger. Kjeminytt.
  • Krengel, Ute (2015). Molecular Basis of Blood-Group-Dependent Diseases Like Cholera.
  • Krengel, Ute (2015). Molecular Basis of Cholera Blood Group Dependence.
  • Krengel, Ute & Burschowsky, Daniel (2015). Chorismate mutase.
  • Manna, Dipankar; Cordara, Gabriele; Pust, Sascha; Goldstein, Irwin J; Winter, Harry C.; Krengel, Ute & Sandvig, Kirsten (2015). PSL1a: a new member in the growing family of fungal chimerolectin.
  • Vogt, Yngve; Thorbjørnsrud, Helen Vikdal; Burschowsky, Daniel; Gorbitz, Carl Henrik & Krengel, Ute (2015). Molekylforskning kan gi ny medisin mot tuberkulose. Apollon : Forskningsmagasin for Universitetet i Oslo.  ISSN 0803-6926.
  • Bousquet, Anna Paula & Krengel, Ute (2014). N-glycolyl GM3 as potential target for cancer immunotherapy.
  • Bousquet, Paula; Abshiru, Nebiyu; Sandvik, Joe Alexander; Pettersen, Erik O; Thiede, Bernd; Woods, Robert; Moreno, Ernesto & Krengel, Ute (2014). Anti-tumor antibodies and hypoxia.
  • Burschowsky, Daniel; Kast, Peter & Krengel, Ute (2014). Towards the structural basis of shikimate pathway regulation in Corynebacterium glutamicum.
  • Bækkelund Langgård, Øyvind; Burschowsky, Daniel; Rongved, Pål & Krengel, Ute (2014). Preparing Liver X Receptors for Structural Studies.
  • Hatlem, Daniel; Heggelund, Julie Elisabeth; Burschowsky, Daniel; Kristiansen, Per Eugen & Krengel, Ute (2014). Characterization of Lipopolysaccharide Binding to the E.coli Heat-labile Enterotoxin.
  • Heggelund, Julie Elisabeth; Prydz, Kristian & Krengel, Ute (2014). Cholera blood-group dependence investigated by X-ray crystallography, CaCo-2 cells and ELISA.
  • Johannesen, Hedda; Bousquet, Paula; Løset, Geir Åge & Krengel, Ute (2014). L`ASSASSINA PROTEIN THAT SPECIFICALLY KILLS TUMOUR CELLS.
  • Johannesen, Hedda; Krengel, Ute; Løset, Geir Åge & Bousquet, Paula (2014). The Assassin - Recombinant single-chain Fv production of the anti-tumour antibody 14F7.
  • Krengel, Ute (2014). Chorismate mutase catalysis: Insights from X-ray structures into catalytic mechanism and biochemical regulation.
  • Manna, Dipankar; Cordara, Gabriele; Goldstein, Irwin J. & Krengel, Ute (2014). Conserved catalytic machinery in the MOA-PSL family of fungal chimerolectins.
  • Manna, Dipankar; Cordera, Gabriele; Goldstein, Irwin J & Krengel, Ute (2014). Conserved catalytic machinery in the MOA-PSL family of fungal chimerolectins.
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2013). Structure of a Semi-Synthetic Chorismate Mutase Reveals the Catalytically Decisive Cation.
  • Bousquet, Paula; Abshiru, Nebiyu; Johansen, Rune Forstrøm; Bjørås, Magnar; Sandvik, Joe Alexander; Pettersen, Erik O; Thiede, Bernd; Woods, Robert; Moreno, Ernesto & Krengel, Ute (2013). A structural and functional study of anti-ganglioside antibodies. International Journal of Molecular Medicine.  ISSN 1107-3756.  32, s S42- S42 Vis sammendrag
  • Bousquet, Paula; Abshiru, Nebiyu; Moreno, Ernesto & Krengel, Ute (2013). MS analysis of the molecular interaction of the anti-tumor antibody 14F7 to its antigen and anti-idiotypic antibody.
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2013). Semi-Synthetic Chorismate Mutase Variant Finally Nails Down Catalytic Mechanism.
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2013). Semi-Synthetic Chorismate Mutase Variant Finally Nails Down Catalytic Mechanism.
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2013). Twinning and other interesting details.
  • Bækkelund Langgård, Øyvind; Burschowsky, Daniel; Rongved, Pål & Krengel, Ute (2013). Preparing Liver X Receptor for Structural Studies.
  • Bækkelund Langgård, Øyvind; Grøthe, Bendik H.; Bousquet, Paula; Burschowsky, Daniel; Rongved, Pål & Krengel, Ute (2013). Preparing Liver X Receptors for Structural Studies.
  • Cordara, Gabriele; Krengel, Ute & Sandvig, Kirsten (2013). Structure-function studies on the Marasmius oreades agglutinin (MOA), a cytotoxic protease.
  • Hatlem, Daniel; Heggelund, Julie Elisabeth; Burschowsky, Daniel; Kristiansen, Per Eugen & Krengel, Ute (2013). Characterization of Lipopolysaccharide binding to E.coli Heat-labile Enterotoxin.
  • Heggelund, Julie Elisabeth & Krengel, Ute (2013). Exploring Cholera Toxin and Heat-Labile Enterotoxin Binding Specificity using SPR and Protein NMR.
  • Heggelund, Julie Elisabeth & Krengel, Ute (2013). Kolera og blodgrupper.
  • Heggelund, Julie Elisabeth; Prydz, Kristian & Krengel, Ute (2013). Cholera toxin's blood-group dependence investigated with CaCo-2 cells and ELISA.
  • Krengel, Ute (2013). Chorismate mutase catalysis: Do all enzymes require transition state stabilization?.
  • Krengel, Ute & Eikeseth, Unni (2013, 28. februar). Kappløpet mot DNA. [Internett].  NRK.
  • Manna, Dipankar; Cordara, Gabriele; Goldstein, Irwin J. & Krengel, Ute (2013). Towards structural and functional characterization of the Marasmius oreades agglutinin (MOA) and its role in host-pathogen interactions.
  • Munack, Steffi; Krengel, Ute & Gundersen, Lise-Lotte (2013). Enzymes of the shikimate pathway of Mycobacterium tuberculosis – Functional Studies and Drug Design.
  • Burschowsky, Daniel; Van Eerde, Jan Hendrik; Ökvist, Mats; Kienhöfer, Alexander; Kast, Peter; Hilvert, Donald & Krengel, Ute (2012). Reaction Mechanism of Chorismate Mutase, a Model Enzyme for Pericyclic Reactions.
  • Bousquet, Paula; Abshiru, Nebiyu; Moreno, Ernesto & Krengel, Ute (2012). Antitumor antibodies - a structural approach.
  • Bousquet, Paula; Abshiru, Nebiyu; Moreno, Ernesto & Krengel, Ute (2012). Structural characterization of the antitumor antibody 14F7.
  • Bousquet, Paula; Abshiru, Nebiyu; Moreno, Ernesto; Madshus, Inger Helene & Krengel, Ute (2012). Antitumor antibodies - a structural approach. International Journal of Molecular Medicine.  ISSN 1107-3756.  30, s S37- S37
  • Bousquet, Paula; Thiede, Bernd; Moreno, Ernesto & Krengel, Ute (2012). Antitumor antibodies - Crystallization and MS analysis.
  • Burschowsky, Daniel & Krengel, Ute (2012). Insights into the Reaction Mechanism of a “Chorismatic” Model Enzyme.
  • Burschowsky, Daniel & Krengel, Ute (2012). Structural investigation of a Bacillus subtilis chorismate mutase variant containing a non-natural amino acid in its active site.
  • Cordara, Gabriele; Goldstein, Irwin; Sandvig, Kirsten & Krengel, Ute (2012). Structure-function studies on the proteolytic activity of the Marasmius oreades agglutinin (MOA), a cytotoxic lectin. Vis sammendrag
  • Cordara, Gabriele; Grahn, Elin; Jacobsen, Wolfgang Mathias; Goldstein, Irwin; Sandvig, Kirsten & Krengel, Ute (2012). Marasmius oreades Agglutinin (MOA): proteolytic activity of a cytotoxic lectin. Vis sammendrag
  • Heggelund, Julie Elisabeth & Krengel, Ute (2012). From heat-labile enterotoxin to cholera toxin - residue by residue.
  • Heggelund, Julie Elisabeth & Krengel, Ute (2012). Kjemi Grand Prix - Molecular basis of cholera blood group dependence.
  • Heggelund, Julie Elisabeth & Krengel, Ute (2012). Molecular basis of cholera blood group dependence.
  • Krengel, Ute (2012). Protein-carbohydrate interactions studied by X-ray crystallography.
  • Krengel, Ute (2012, 08. juni). Ut av Afrika, in i blodet.  Aftenposten.
  • Krengel, Ute (2012). What is the Molecular Basis of Cholera Blood Group Dependence?.
  • Krengel, Ute & Heggelund, Julie Elisabeth (2012, 20. oktober). Årets Nobelpris i kjemi er en gullgruve for legemiddelindustrien.  Dagens Næringsliv.
  • Krengel, Ute; Heggelund, Julie Elisabeth & Jemterud, Torkild (2012, 11. oktober). Interview om Nobel pris i Kjemi 2012. [Radio].  NRK (podcast Ekko viten).
  • Munack, Steffi; Cordara, Gabriele; Van Eerde, Jan Hendrik; Kamarauskaite, Jurate; Roderer, Kathrin; Kast, Peter & Krengel, Ute (2012). Towards New Drugs Against Tuberculosis.
  • Munack, Steffi; Roderer, Kathrin; Kamarauskaite, Jurate; Cordara, Gabriele; van Eerde, André; Kast, Peter & Krengel, Ute (2012). Towards New Drugs Against Tuberculosis.
  • Vogt, Yngve; Krengel, Ute & Heggelund, Julie Elisabeth (2012, 31. august). Røntgenkjemiker løser koleragåte.  Apollon.
  • Munack, Steffi; Leroux, Vincent; Roderer, Katrin; Ökvist, Mats; Bryntesen, Tina; Thiemicke, Alexander; Van Eerde, Jan Hendrik; Kast, Peter; Gundersen, Lise-Lotte & Krengel, Ute (2011). A structure-guided approach to new tuberculosis drugs – potential inhibiyors of Mycobacterium tuberculosis chorismate mutase.
  • Abelsen, Atle & Krengel, Ute (2011, 19. januar). Vil gi bedre vaksine og medisin. [Internett].  NFR - SYNCHROTRON (webside).

Se alle arbeider i Cristin

Publisert 12. juli 2010 14:42 - Sist endret 28. apr. 2015 09:02