Bioactive natural products and health effects (BioNatH)

About the group

 The research group is focusing on:

• Isolation and structurally elucidation of
  • Carbohydrate polymers
  • Polyphenolic compounds
  • Low molecular natural products
• Biologically  testing of
  • Complement fixation
  • Radical scavenging
  • Macrophage activation
  • Inhibition of peroxidative enzymes

Projects

BioNatH is involved in the following projects:

• Glyconor
• Potential of black aronia berries (Aronia melanocarpa) in treatment of urinary tract infections
• The Malian Medicinal Plant Project
• INFIGUT (Influence of polysaccharide based dietary fIbre on gut microflora and the human health)
• ADDBAR (Added value products from barley)
• Fiber and health: Interaction with proteases 

 

Studieprogrammer og emner

• FRM 4030 - Research Preparation course in Pharmacognosy and Medicinal Chemistry
• FRM 5105 - Polysaccharides of Pharmaceutical Interest; Chemical Properties
• FRM 5110 - Polysaccharides of Pharmaceutical Interest; Physical and Chemical Properties, as Well as Biological Activity
• FRM 5410 - Pharmaceutical natural products
• FRM 5420 - Ethnopharmacology
• FRM 5440 - Selected Pharmaceutical natural products
• FRM9920 - NFIF - Ethnopharmacology

Resources

Equipment and instrumentation:

BioNatH have instrumentation for extraction, fractionation, isolation and structure elucidation of natural products, both low- and high molecular substances. We have methods for antioxidant, enzyme inhibition and complement tests. 

Extraction:

• Accelerated Solvent Extraction (ASE)
• Soxhlet

Chromatography:

• CA-TLC, kromatotron
• GC
• GC-MS
• FPLC
• HPLC-DAD
• HPLC-UV-VIS
• Preparative HPLC-UV
• HPLC-RI
• HPAEC-PAD

 

Methodologies:

• Carbohydrate analyses
• Antioxidant analyses