Siste publikasjoner

• Gravningen, Kirsten Midttun; Field, Nigel; Blix, Hege Salvesen; Asfeldt, anne mette & Småbrekke, Lars (2020). Non-prescription purchase of antibiotics during travel abroad among a general adult population in Norway: Findings from the seventh Tromsø Study. PLOS ONE.  ISSN 1932-6203.  15(2) . doi: 10.1371/journal.pone.0228792 Fulltekst i vitenarkiv.
• Holme, Jørn Andreas; Øya, Elisabeth Tveiten; Afanou, Komlavi Anani; Øvrevik, Johan & Wijnand, Eduard (2020). Characterization and pro‐inflammatory potential of indoor mold particles. Indoor Air: International Journal of Indoor Environment and Health.  ISSN 0905-6947. . doi: 10.1111/ina.12656 Vis sammendrag

  A number of epidemiological studies find an association between indoor air dampness and respiratory health effects. This is often suggested to be linked to enhanced mold growth. However, the role of mold are obviously difficult to disentangle from other dampness related exposure including microbes as well as non‐biological particles and chemical pollutants. The association may partly be due to visible mycelial growth and a characteristic musty smell of mold. Thus, the potential role of mold exposure should be further explored by evaluating information from experimental studies elucidating possible mechanistic links. Such studies show that exposure to spores and hyphal fragments may act as allergens and pro‐inflammatory mediators, and that they may damage airways by the production of toxins, enzymes and volatile organic compounds. In the present review, we hypothesizes that continuous exposure to mold particles may result in chronic low‐grade pro‐inflammatory responses contributing to respiratory diseases. We summarize some of the main methods for detection and characterization of fungal aerosols and highlight in vitro research elucidating how molds may induce toxicity and pro‐inflammatory reactions in human cell models relevant for airway exposure. Data suggest that the fraction of fungal hyphal fragments in indoor air is much higher than that of airborne spores, and the hyphal fragments often have a higher pro‐inflammatory potential. Thus, hyphal fragments of prevalent mold species with strong pro‐inflammatory potential may be particularly relevant candidates for respiratory diseases associated with damp/mold‐contaminated indoor air. Future studies linking of indoor air dampness with health effects should assess the toxicity and pro‐inflammatory potential of indoor air particulate matter, and combined this information with a better characterization of biological components including hyphal fragments from both pathogenic and non‐pathogenic mold species. Such studies may increase our understanding of the potential role of mold exposure.

• Karlsen, Jan (2019). The history of the ISEO: 1969-2019. Natural Volatiles and Essential Oils (NVEO).  6(1), s 1- 17
• Åsberg, Anders; Bjerre, Anna Kristina; Almaas, Runar; Luis-Lima, Sergio; Robertsen, Ida; Salvador, Cathrin Lytomt; Porrini, Esteban; Schwartz, George; Hartmann, Anders & Bergan, Stein (2019). Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance. Kidney International Reports.  ISSN 2468-0249.  5(2), s 189- 198 . doi: 10.1016/j.ekir.2019.11.012
• Gawel, Kinga Aurelia; Turski, Waldemar A.; van der Ent, Wietske; Mathai, Benan John; Kirstein-Smardzewska, Karolina Joanna; Simonsen, Anne & Esguerra, Camila V. (2019). Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene. Molecular Neurobiology.  ISSN 0893-7648. . doi: 10.1007/s12035-019-01860-x
• Kongstorp, Mette; Bogen, Inger Lise; Stiris, Tom & Andersen, Jannike Mørch (2019). High accumulation of methadone compared with buprenorphine in fetal rat brain after maternal exposure. Journal of Pharmacology and Experimental Therapeutics.  ISSN 0022-3565.  371(1), s 130- 137 . doi: 10.1124/jpet.119.259531
• Thaulow, Christian Magnus; Berild, Dag; Blix, Hege Salvesen; Brigtsen, Anne Karin; Myklebust, Tor Åge & Eriksen, Beate Horsberg (2019). Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital. Frontiers in pediatrics.  ISSN 2296-2360.  7:440, s 1- 11 . doi: 10.3389/fped.2019.00440 Fulltekst i vitenarkiv.
• Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein & Halvorsen, Bente (2019). Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis.  ISSN 0021-9150.  s 1- 9 . doi: 10.1016/j.atherosclerosis.2019.12.008 Fulltekst i vitenarkiv.

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• Hurum, Jørn Harald; Helleve, Torstein & van Hulsen, Esther (2019). Livsfarlig leksikon. Vigmostad & Bjørke.  ISBN 9788241950278.  88 s.

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• Heggelund, Gørild; Andresen, Steinar E; Rosendal, G. Kristin; Lin, Yan & Steindal, Eirik Hovland (2020). Implementing the Minamata Convention: Will China deliver?.
• Helleve, Torstein & Granås, Anne Gerd (2020, 02. mars). Psykisk utviklingshemma fekk betre medisinering etter rydding. [Fagblad].  www.forskning.no. Vis sammendrag

  I 2016 tok utviklingssenteret for heimetenesta i Oslo kommune initiativ til eit prosjekt som skulle sjå på legemiddelbruken til ei gruppe psykisk utviklingshemma. – Dei 40 pasientane som vart valde ut, var i alderen 34 til 77 år som heimetenestene meinte kunne ha spesielt godt utbyte av ein slik gjennomgang, fortel professor Anne Gerd Granås ved Farmasøytisk institutt ved Universitetet i Oslo. Ho understrekar at sidan utvalet er såpass lite og ikkje tilfeldig, kan ein ikkje generalisera ut frå funna. Dei underliggjande problemstillingane som vert avdekte, meiner ho likevel gjeld andre grupper òg, sjølv om pasientane i dette prosjektet var handplukka. – Mange av dei tok ei lang rekkje legemiddel. Gjennomsnittet låg rundt tolv ulike legemiddel per pasient. Det er til samanlikning dobbelt så høgt som snittet for pasientar på sjukeheim, fortel ho.

• Malterud, Karl Egil & Helleve, Torstein (2020, 10. januar). Lokale healarar kan ha rett om tradisjonelt medisintre. [Internett].  titan.uio.no/node/3545.
• Høye, Sigurd; Lindbæk, Morten & Blix, Hege Salvesen (2019). Effects of an easy-to-implement, sustainable antimicrobial stewardship intervention in primary care – the ENORM (Educational intervention in NORwegian Municipalities for antibiotic treatment in line with guidelines) study.
• Tveit, Kristine; Hermann, Monica; Waade, Ragnhild Birkeland & Molden, Espen (2019). Dose intensity of antidepressants in older persons 2007-2017 – a study based on therapeutic drug monitoring data.
• Lyche, Jan Ludvig; Dirven, Hubert; Låg, Marit; Nilsen, Asbjørn Magne; Borgå, Katrine; Eklo, Ole Martin; Grung, Merete; Sverdrup, Line Emilie & Källqvist, Torsten (2019). Risk Assessment of the Metabolite M44 of Bixafen, One of the Active Substancesin Aviator Xpro EC225. European Journal of Nutrition and Food Safety.  ISSN 2347-5641.  9(4), s 317- 318 . doi: 10.9734/EJNFS/2019/v9i430077
• Eklo, Ole Martin; Almvik, Marit; Hole, Halvard; Nyborg, Åge Arild; Stenrød, Marianne; Borgå, Katrine; Dirven, Hubert; Grung, Merete; Lyche, Jan Ludvig; Låg, Marit; Nilsen, Asbjørn Magne; Sverdrup, Line Emilie & Källqvist, Torsten (2019). Degradation and Mobility of Pesticides in Norwegian Soils. European Journal of Nutrition and Food Safety.  ISSN 2347-5641.  9(3), s 303- 305 . doi: 10.9734/EJNFS/2019/v9i330071
• Dirven, Hubert; Lyche, Jan Ludvig; Låg, Marit; Nilsen, Asbjørn Magne; Borgå, Katrine; Eklo, Ole Martin; Grung, Merete; Sverdrup, Line Emilie & Källqvist, Torsten (2019). Genotoxic Assessment of the Metabolite M-11 of Mepanipyrim, the Active Ingredient in the Plant Protection Product FRUPICA SC. European Journal of Nutrition and Food Safety.  ISSN 2347-5641.  9(3), s 306- 307 . doi: 10.9734/EJNFS/2019/v9i330072
• Schure, Anna Theresia Maria ter; Pillai, Anusree; Gopalakrishnan Saroja, Seethapathy; Bhavani Shankar, M.; Ravikanth, G; Puri, Rajindra K.; de Boer, Hugo & Boessenkool, Sanne (2019). Dietary competition between wild and domestic herbivores in a wildlife sanctuary.
• Schure, Anna Theresia Maria ter; Pillai, Anusree; Gopalakrishnan Saroja, Seethapathy; Bhavani Shankar, M.; Ravikanth, G.; Puri, Rajindra K.; de Boer, Hugo & Boessenkool, Sanne (2019). Dietary niche partitioning in domestic and wild herbivores in Southern India.
• Schure, Anna Theresia Maria ter; Pillai, Anusree; Gopalakrishnan Saroja, Seethapathy; Bhavani Shankar, M.; Ravikanth, G.; Puri, Rajindra K.; de Boer, Hugo & Boessenkool, Sanne (2019). Food competition between wild and domestic herbivores in Southern India.

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