Siste publikasjoner

• Bavlovic Piskackova, Hana; Øiestad, Elisabeth Leere; Vanova, Nela; Lengvarska, Julia; Štěrbová-Kovaříková, Petra & Pedersen-Bjergaard, Stig (2021). Electromembrane extraction of anthracyclines from plasma: Comparison with conventional extraction techniques. Talanta: The International Journal of Pure and Applied Analytical Chemistry.  ISSN 0039-9140.  223 . doi: 10.1016/j.talanta.2020.121748
• Anstensrud, Anne Kristine; Molden, Espen; Haug, Hans Jørgen; Qazi, Rehman; Muriq, Hysen; Fosshaug, Linn Elisabeth Lillerud; Spigset, Olav & Øie, Erik (2020). Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction – a prospective observational study. European Journal of Clinical Pharmacology.  ISSN 0031-6970.  76, s 673- 683 . doi: 10.1007/s00228-020-02832-0
• Lea, Marianne; Mowe, Morten; Molden, Espen; Kvernrød, Kristin; Skovlund, Eva & Mathiesen, Liv (2020). Effect of medicines management versus standard care on readmissions in multimorbid patients: a randomised controlled trial. BMJ Open.  ISSN 2044-6055.  10 . doi: 10.1136/bmjopen-2020-041558
• Eig, Ruth Davey; Harbin, Nicolay Jonassen; Gjelstad, Svein; Høye, Sigurd; Jensen, Siri; Lindbæk, Morten & Blix, Hege Salvesen (2020). RASK – Promoting appropriate use of antibiotics in municipal healthcare institutions, In Gunnar Skov Simonsen; Hege Salvesen Blix; Kari Grave & Anne Margrete Urdahl (ed.),  NORM/NORM-vet 2019. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway.  NORM/NORM-VET.  Kapittel.  s 42 - 43
• Harbin, Nicolay Jonassen; Eig, Ruth Davey; Høye, Sigurd; Gjelstad, Svein; Jensen, Siri; Lindbæk, Morten & Blix, Hege Salvesen (2020). Antibiotic use in nursing homes, In Gunnar Skov Simonsen; Hege Salvesen Blix; Kari Grave & Anne Margrete Urdahl (ed.),  NORM/NORM-vet 2019. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway.  NORM/NORM-VET.  Kapittel.  s 42 - 42
• Høye, Sigurd; Lindbæk, Morten & Blix, Hege Salvesen (2020). RAK – Promoting appropriate use of antibiotics among general practitioners, In Gunnar Skov Simonsen; Hege Salvesen Blix; Kari Grave & Anne Margrete Urdahl (ed.),  NORM/NORM-vet 2019. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway.  NORM/NORM-VET.  Kapittel.  s 40 - 41
• Andreassen, Vigdis; Waagsbø, Bjørn & Blix, Hege Salvesen (2020). Bruk av ciprofloksacin ved et lokalsykehus. Tidsskrift for Den norske legeforening.  ISSN 0029-2001. . doi: 10.4045/tidsskr.20.0146
• Ritschl, Valentin; Stamm, Tanja; Aletaha, Daniel; Bijlsma, Hans; Böhm, Peter; Drăgoi, Răzvan Gabriel; Dures, Emma; Estévez-López, Fernando; Gossec, Laure; Iagnocco, Annamaria; Marques, Andrea; Moholt, Ellen; Nudel, Michal; van den Bemt, Bart; Viktil, Kirsten Kilvik; Voshaar, Marieke; De Thurah, Annette & Carmona, Loreto (2020). 2020 EULAR points to consider for the prevention, screening, assessment and management of non-adherence to treatment in people with rheumatic and musculoskeletal diseases for use in clinical practice. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  s 1- 7 . doi: 10.1136/annrheumdis-2020-218986
• Lee, Yunsung; Jacobsen, Kristine Løkås; Denault, William Robert Paul; Nustad, Haakon Egdetveit; Page, Christian; Lyle, Robert; Lee-Ødegård, Sindre; Moen, Gunn-Helen; Prasad, Rashmi B.; Groop, Leif C.; Sletner, Line; Sommer, Christine; Magnus, Maria Christine; Gjessing, Håkon K.; Harris, Jennifer Ruth; Magnus, Per; Håberg, Siri Eldevik; Jugessur, Astanand & Bohlin, Jon (2020). Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array. BMC Genomics.  ISSN 1471-2164.  21(1) . doi: 10.1186/s12864-020-07168-8
• Czajkowski, Nikolai Olavi; Kendler, Kenneth S; Torvik, Fartein Ask; Ystrøm, Eivind; Rosenström, Tom Henrik; Gillespie, Nathan & Reichborn-Kjennerud, Ted (2020). Caffeine consumption, toxicity, tolerance and withdrawal; shared genetic influences with normative personality and personality disorder traits. Experimental and clinical psychopharmacology.  ISSN 1064-1297. . doi: 10.1037/pha0000429
• Milosavljević, Filip; Bukvić, Nikola; Pavlović, Zorana; Miljević, Čedo; Pešić, Vesna; Molden, Espen; Ingelman-Sundberg, Magnus; Leucht, Stefan & Jukic, Marin M. (2020). Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status with Antidepressant and Antipsychotic Exposure: A Systematic Review and Meta-analysis. JAMA psychiatry.  ISSN 2168-6238. . doi: 10.1001/jamapsychiatry.2020.3643
• Gustavsen, Marte Theie; Midtvedt, Karsten; Robertsen, Ida; Woillard, Jean-Baptiste; Debord, Jean; Klaasen, Rolf; Vethe, Nils Tore; Bergan, Stein & Åsberg, Anders (2020). Fasting Status and Circadian Variation Must be Considered When Performing AUC-based Therapeutic Drug Monitoring of Tacrolimus in Renal Transplant Recipients. Clinical and Translational Science.  ISSN 1752-8054.  13(6), s 1327- 1335 . doi: 10.1111/cts.12833
• Smith, Robert Løvsletten; Tveito, Marit; Kyllesø, Lennart; Jucik, Marin M.; Ingelman-Sundberg, Magnus; Andreassen, Ole Andreas & Molden, Espen (2020). Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders. Schizophrenia Research.  ISSN 0920-9964. . doi: 10.1016/j.schres.2020.11.025 Vis sammendrag

  Background: Nonadherence to antipsychotics may cause relapse and hospitalizations in patients with psychotic disorders. The purpose was to quantify and compare the outpatient's nonadherence rates of atypical antipsychotics by objective detection in blood samples. Methods: Totally, 13,217 outpatients with therapeutic drug monitoring (TDM) data of atypical antipsychotics were included. An event of complete nonadherence was defined as an occurrence of undetectable level of a prescribed antipsychotic in the blood sample submitted for TDM. Patients with such an event(s) were defined as nonadherent of the respective drug treatment (outcome). The rates of nonadherence patients were compared between the drugs by logistic regression. Results: In the study population, 70.2% of the patients were prescribed doses compliant with a schizophrenia diagnosis. The mean olanzapine equivalent dose in the population was 13.4 mg (95% confidence interval (CI): 13.3, 13.6). The frequency of nonadherence patients, regardless of drug, was 3.7% (CI: 3.4-4.0). The nonadherence patient rate was lowest in clozapine-treated patients (2.2%; CI: 1.5-2.8), followed by aripiprazole (2.3%; 1.7-2.8), risperidone (2.4%; 1.6-3.0), quetiapine (2.8%; 2.3-3.2) and olanzapine (4.9%; 4.1-5.3). Users of olanzapine had significantly higher risk of complete nonadherence (Odds ratio: 1.9; CI: 1.6-2.3, p < 0.001) compared to patients treated with other antipsychotics as a group. Conclusions: In this study, complete nonadherence of atypical antipsychotics, measured as undetectable blood level, was disclosed for ~5% of outpatients with psychotic disorders. The rate of complete nonadherence was significantly higher during olanzapine treatment compared to other atypical antipsychotics. Further studies should investigate if this reflects drug differences in tolerability or other causal relationships. Keywords: Atypical antipsychotics; Nonadherence; Olanzapine; Outpatient treatment; Therapeutic drug monitoring.

• Ritschl, Valentin; Stamm, Tanja; Aletaha, Daniel; Bijlsma, Hans; Böhm, Peter; Drăgoi, Răzvan Gabriel; Dures, Emma; Estévez-López, Fernando; Gossec, Laure; Iagnocco, Annamaria; Negrón, José B; Nudel, Michal; Marques, Andréa; Moholt, Ellen; Skrubbeltrang, Conni; van den Bemt, Bart; Viktil, Kirsten Kilvik; Voshaar, Marieke; Carmona, Loreto & de Thurah, Annette (2020). Prevention, screening, assessing and managing of non-adherent behaviour in people with rheumatic and musculoskeletal diseases: systematic reviews informing the 2020 EULAR points to consider. RMD Open.  ISSN 2056-5933.  6:e001432(3), s 1- 11 . doi: 10.1136/rmdopen-2020-001432
• Smith, Robert Løvsletten; O’Connell, Kevin; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Andreassen, Ole Andreas & Molden, Espen (2020). Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits. Translational Psychiatry.  ISSN 2158-3188.  10(1), s 1- 10 . doi: 10.1038/s41398-020-00888-1 Fulltekst i vitenarkiv.

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• Hurum, Jørn Harald & Helleve, Torstein (2020). Borgias forbudte bok. Cappelen Damm AS.  ISBN 9788202660789.  218 s.

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• Hurum, Jørn Harald & Helleve, Torstein (2020). Livsfarlig leksikon - andre foredrag.
• Hurum, Jørn Harald & Helleve, Torstein (2020). Livsfarlig leksikon - første foredrag.
• Simonsen, Gunnar Skov; Blix, Hege Salvesen; Grave, Kari & Urdahl, Anne Margrete (ed.) (2020). NORM/NORM-vet 2019. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway. NORM/NORM-VET. 2020.
• Goll, Guro Løvik & Kvien, Tore Kristian (2020). What next after biologic therapy fails in rheumatoid arthritis?. New England Journal of Medicine.  ISSN 0028-4793.  383(16), s 1588- 1589 . doi: 10.1056/NEJMe2026142

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