Neurobiology - Fyhn Group

The brain has a remarkable ability to adapt to changing environments, but the mechanisms underlying these processes remain elusive.

The Fyhn group works to identify the neural fingerprint that reflects

learning of sensory experiences in cortical circuits, from structural

changes of synapses to changes in the population code of neural

ensembles in behaving animals. To achieve this, we use large scale

extracellular recordings of populations of neurons and transcranial

two-photon laser scanning microscopy to identify structural and

functional changes of identified neurons. A better understanding of

the mechanisms underlying basic cortical plasticity and function will

untangle how experience modifies cortical circuits to form long-lasting

memories. It will also have a significant impact on our understanding

of both normal and diseased brain function.


Marianne Fyhn is director of Centre for Integrative Neuroplasticity

(CINPLA). CINPLA is a strategic research initiative at the MN Faculty

at UiO, aiming to reveal mechanisms underlying the brain’s ability

to change and learn from experiences. By integrating experimental

methods with physics-based computational modelling and analysis,

we work to develop a creative and inspiring consortium aiming to

deliver groundbreaking research and develop an interdisciplinary and

high-quality educational program in Neuroscience at the faculty.

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Marianne Fyhn