Reidun Sirevåg

Faglige interesser

Jeg er interessert i mikroorganismenes biologi generelt.
Jeg har i alle år vært interessert i fysiologi, biokjemi og molekylærbiologi hos ulike fototrofe bakterier. I de senere årene har jeg arbeidet spesielt med proteiner fra fototrofe bakterier som lever ved høy temperatur i varme kilder. Jeg har også hatt mer anvendte prosjekter i samarbeid med industrien for å utvikle raske, molekylærbiologiske  metoder for påvisning av bakterier i drikkevann.

Undervisning

MBV3060- Generell mikrobiologi

MBV4130- Prokaryotenes biologi

Ansettelser

Adjunkt, Ris gymnas 1961-1966

Vitenskapelig assistent, UiO  1966-1972

Førsteamanuensis, UiO 1977-1988

Professor i mikrobiologi, UiO 1988-2009

Generalsekretær, Det Norske Videnskaps-Akademi 2001-2009

 

Bakgrunn

Cand.mag. i realfag fra UiO, 1961

M.Sc. i mikrobiologi fra Vassar College, N.Y,  1968. Avhandling om sporulering hos Bacillus.

Dr. philos. UiO i 1977. Avhandling ”Carbon metabolism in Chlorobium thiosulfatophilum”.

Forskningsopphold ved Harvard University, 1970/71

Forskningsopphold ved UCSB, Santa Barbara, California 1986/87

Forskningsopphold ved UCSB, Santa Barbara, California 2002

 

Verv

Styreleder i Centre for Ecological and Evolutionary Syntethsis (CEES) ved UiO

Styremedlem i grunnforskningsprogrammet VISTA (finansiert av Statoil i samarbeid med Det Norske Videnskaps-Akademi

Medlem av priskomiteen for godt læringsmiljø, UiO

Samarbeid

Jeg samarbeider for tiden med miljøer på Folkehelseinstituttet på et prosjekt om Legionella

Publikasjoner

  • Angles d'Auriac, Marc & Sirevåg, Reidun (2018). Multiplex PCR for the simultaneous detection of the Enterobacterial gene wecA, the Shiga Toxin genes (stx1 and stx2) and the Intimin gene (eae). BMC Research Notes.  ISSN 1756-0500.  11(360) . doi: 10.1186/s13104-018-3457-8
  • Lærum, Ole Didrik; Helsvig, Kim Gunnar & Sirevåg, Reidun (2009). The Norwegian Academy of Science and Letters: current revival of a time-honoured institution. International Journal of Technology Management.  ISSN 0267-5730.  46(1-2), s 27- 37
  • Nederbragt, Alexander J; Balasingham, Anusha; Sirevåg, Reidun; Utkilen, Hans Chr.; Jakobsen, Kjetill S & Anderson-Glenna, Mary (2008). Multiple-locus variable-number tandem repeat analysis of Legionella pneumophila using multi-colored capillary electrophoresis. Journal of Microbiological Methods.  ISSN 0167-7012.  73(2), s 111- 117 . doi: 10.1016/j.mimet.2008.02.007
  • Gulliksen, A; Solli, Lars Anders; Drese, KS; Karlsen, F; Sorensen, O; Karlsen, F; Rogne, H; Hovig, Johannes Eivind; Rogne, H; Hovig, E; Sirevåg, Reidun & Sirevag, R (2005). Parallel nanoliter detection of cancer markers using polymer microchips. Lab on a Chip.  ISSN 1473-0189.  5
  • Gulliksen, Anja; Solli, Lars Anders; Drese, Klaus Stefan; Sørensen, Olaf; Karlsen, Frank; Rogne, Henrik; Hovig, Eivind & Sirevåg, Reidun (2005). Parallel nanoliter detection of cancer markers using polymer microchips. Lab on a Chip.  ISSN 1473-0189.  5(4), s 416- 420 Vis sammendrag
  • Eijsink, Vincent; Bjørk, Alexandra; Gåseidnes, Sigrid; Sirevåg, Reidun; Synstad, Bjørnar; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability. Journal of Biotechnology.  ISSN 0168-1656.  113, s 105- 120
  • Gulliksen, A; Solli, Christian; Solli, Lars; Karlsen, F; Rogne, H; Hovig, E; Hovig, Eivind; Nordstrøm, Trine; Nordstrom, T; Sirevag, R & Sirevåg, Reidun (2004). Real-time nucleic acid sequence-based amplification in nanoliter volumes. Analytical Chemistry.  ISSN 0003-2700.  76, s 9- 14
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Sirevåg, Reidun & Eijsink, Vincent (2004). Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  341, s 1215- 1226
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2004). Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  341, s 1215- 1226
  • Eijsink, Vincent; Gåseidnes, Sigrid; Synstad, Bjørnar; Bjørk, Alexandra; Sirevåg, Reidun; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability. Journal of Biotechnology.  ISSN 0168-1656.  113, s 105- 120
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface. Journal of Molecular Biology.  ISSN 0022-2836.  334, s 811- 821
  • Bjørk, Alexandra; Mantzilas, Dimitrios; Sirevåg, Reidun & Eijsink, Vincent G. H. (2003). Electrostatic interactions across the dimer-dimer interface contribute to the pH-dependent stability of a tetrameric malate dehydrogenase. FEBS Letters.  ISSN 0014-5793.  553, s 423- 426
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2003). Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface. ?.  334, s 811- 821
  • Bjørk, Alexandra; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2003). A network of salt bridges contributes to the pH-dependent stability and oligomerization state of a tetrameric malate dehydrogenase. FEBS Letters.  ISSN 0014-5793.  553, s 423- 426
  • Dalhus, Bjørn; Saarinen, Markuu; Sauer, Uwe H.; Eker, Per; Johansson, Kenth; Karlsson, Andreas; Ramaswamy, S.; Bjørk, Alexandra; Synstad, Bjørnar; Naterstad, Kristine; Sirevåg, Reidun & Eklund, Hans (2002). Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases. Journal of Molecular Biology.  ISSN 0022-2836.  318(3), s 707- 721 . doi: 10.1016/S0022-2836(02)00050-5 Vis sammendrag
  • Roberts, Hildegarde; Shaw, Terri; Sirevåg, Reidun; Hermansen, Leonila Fajardo & Berg, James (2000). Field evaluation of a semiautomated method for rapid and simple analysis of recreational water microbiological quality. Applied and Environmental Microbiology.  ISSN 0099-2240.  66(10), s 4401- 4407 Vis sammendrag
  • Kolstø, Anne-Brit; Naterstad, K. & Sirevåg, Reidun (1995). Physical map of the genome of the green phototrophic bacterium Chlorobium tepidum. Journal of Bacteriology.  ISSN 0021-9193.  (177), s 5480- 5484
  • Naterstad, K.; Kolstø, Anne-Brit & Sirevåg, Reidun (1995). Physical map of the genome of the green phototropic bacterium Chlorobium tepidum. Journal of Bacteriology.  ISSN 0021-9193.  177, s 5480- 5484

Se alle arbeider i Cristin

  • Østerud, Øyvind; Sirevåg, Reidun & Lærum, Ole Didrik (red.) (2009). Det Norske Videnskaps-Akademi Årbok 2008. Novus Forlag.  ISBN 9788270995547.  410 s.

Se alle arbeider i Cristin

  • Buchanan, Bob B.; Sirevåg, Reidun; Fuchs, Georg; Ivanovksy, Ruslan N.; Igarashi, Yasuo; Ishii, Masaharu; Tabita, F. Robert & Berg, Ivan A. (2017). The Arnon-Buchanan cycle; a retrospective, 1966-2016. Photosynthesis Research.  ISSN 0166-8595.  134(2), s 117- 131 . doi: 10.1007/s11120-017-0429-0
  • Helsvig, Kim Gunnar; Sirevåg, Reidun & Lærum, Ole Didrik (2006). Norwegian Academy of Science and Letters. From National Policy to Global Science. Allea Biennial Yearbook.  s 121- 133
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2004). Stabilization of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2004). Stabilization of a tetrameric malate dehydrogenase.
  • Eijsink, Vincent; Bjørk, Alexandra; Gåseidnes, Sigrid; Sirevåg, Reidun; Synstad, Bjørnar; Van den Burg, Bertus & Vriend, Gert (2004). Rational engineering of enzyme stability.
  • Benestad, Ingun; Ytteborg, Elisabeth; Vanberg, Christin & Sirevåg, Reidun (2003). Two operons for chaperones in Chloroflexus aurantiacus.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Malate dehydrogenase from mesophilic and thermophilic green bacteria.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eijsink, Vincent G. H. & Sirevåg, Reidun (2003). Structural basis for protein thermostability; analysis of interactions within a protein oligomer and engeneering towards higher thermostability.
  • Bjørk, Alexandra; Mantzilas, Dimitris; Sirevåg, Reidun & Eijsink, Vincent (2003). Stabilization of tetrameric malate dehydrogenase from Chloroflexus aurantiacus by engineering of an ionic network in the dimer-dimer interface.
  • Angles d'Auriac, Marc & Sirevåg, Reidun (2002). NEW PRIMERS FOR THE DETECTION AND IDENTIFICATION OF BACTERIAL INDICATOR GROUPS AND VIRULENCE FACTORS.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). STABILIZATION OF TETRAMERIC MALATE DEHYDROGENASE FROM CHLOROFLEXUS AURANTIACUS BY ENGINEERING AN IONIC NETWORK IN THE DIMER-DIMER INTERFACE.
  • Bjørk, Alexandra; Mantzilas, Dimitrios; Dalhus, Bjørn; Eijsink, Vincent G. H. & Sirevåg, Reidun (2002). STABILIZATION OF TETRAMERIC MALATE DEHYDROGENASE FROM CHLOROFLEXUS AURANTIACUS BY ENGINEERING AN IONIC NETWORK IN THE DIMER-DIMER INTERFACE.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eijsink, Vincent G. H.; Mantzilas, Dimitrios & Sirevåg, Reidun (2002). Analysis of an ionic network within a protein oligomer and engeneering towards higher thermostability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Sirevåg, Reidun & Eklund, Hans (2002). Structural basis for protein thermostability - crystal structures of thermostable tetrameric malate dehydrogenases.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2002). Stabilization of tetrameric malate dehydrogenase from Chloroflexus aurantiacus by engineering an ionic network in the dimer-dimer interface.
  • Eijsink, Vincent; Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris & Sirevåg, Reidun (2002). Engineering the stability and oligomerization state of a tetrameric malate dehydrogenase.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitrios; Eijsink, Vincent G. H. & Sirevåg, Reidun (2001). Mutations at the dimer-dimer interface in tetrameric malate dehydrogenase from Chloroflexus aurantiacus have large effects on thermal stability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Eklund, Hans & Sirevåg, Reidun (2001). Crystal structures of MDHs from thermophilic bacteria: structural basis for protein thermostability.
  • Dalhus, Bjørn; Bjørk, Alexandra; Sirevåg, Reidun & Eklund, Hans (2001). Crystal structure of MDHs from thermophilic bacteria - structural basis for thermophilic protein stability.
  • Vanberg, Christin; Bjørk, Alexandra & Sirevåg, Reidun (2001). The moderate thermophilic green gliding bacterium Chloroflexus aurantiacus contains to alleles for chaperonins.
  • Bjørk, Alexandra; Dalhus, Bjørn; Mantzilas, Dimitris; Eijsink, Vincent & Sirevåg, Reidun (2001). Mutations at the dimer-dimer interface in tetrameric malate dehydrogenase from Chloroflexus aurantiacus have large effects on thermal stability.
  • Bjørk, Alexandra; Eijsink, Vincent G. H. & Sirevåg, Reidun (2000). Thermostability of tetrameric malate dehydrogenase from the green, gliding bacterium Chloroflexus aurantiacus.
  • Vanberg, Christin; Bjørk, Alexandra & Sirevåg, Reidun (2000). Molecular chaperones from the moderate thermophilic, green gliding bacterium Chloroflexus aurantiacus.
  • Bjørk, Alexandra; Molden, Tor; Torgunrud, Annette & Sirevåg, Reidun (1999). Thermostable malate dehydrogenases from phototrophic bacteria. Vis sammendrag
  • Karlsen, Frank; Andreassen, Trine-Merethe; Rabone, Marian; Skrodenyte, Vesta; Sirevåg, Reidun; Eckner, Karl; D´Auriac, Marc Angles; Berg, James; Bergseth, Steinar & Charnock, Colin (1999). Development of molecular methods for rapid detection of coliform bacteria in water. Vis sammendrag
  • Molden, Tor; Bjørk, Alexandra; Tooming, Ave & Sirevåg, Reidun (1999). Thermostability in Chloroflexus aurantiacus. Vis sammendrag
  • Molden, Tor; Bjørk, Alexandra; Tooming, Ave & Sirevåg, Reidun (1999). Thermostability in Chloroflexus aurantiacus. Vis sammendrag
  • Tooming, Ave & Sirevåg, Reidun (1999). Induction of molecular chaperones in the thermophilic green bacterium Chloroflexus aurantiacus. Vis sammendrag

Se alle arbeider i Cristin

Publisert 20. jan. 2011 15:32 - Sist endret 24. okt. 2017 12:20