We show that systemic injections of PHP.eB AAVs to express GECIs is a highly promising technique for imaging neural activity and circumvent the need for transgenic GECI expressing mouse lines. We also establish the use of novel soma-targeted GECIs that outperform current Ca2+ indicators using both systemic and local virus injections.
In order to navigate you have to keep track of direction, speed and distance. Grid cells constitute a mental map of space almost like the brains GPS. It has been suggested that rhythmic brain waves (theta oscillations) carry information about speed and direction - essential for grid cell coding.
A reliable sense of space is essential for daily life and memory formation. Breaking down the extracellular matrix around grid cells makes the mental map unstable [Nature Communications 11th of January, 2021].
The CompSci program at the Faculty of Mathematics and Natural Sciences at the University of Oslo will recruit 32 PhD fellowship positions in two calls.
Read about the work of Elise Holter Thompson at Forskning.no (Norwegian only): Lagring av minner i hjernen – hva kan det si oss om demens?
On December 11th, Elise Holter Thompson successfully defended her PhD thesis "Perineuronal nets in memory processing and behavior."
Listen to Gaute Einevoll talk about neuroscience and technology in these podcast episodes (Norwegian only):
On November 20th, Marte Julie Sætra successfully defended her PhD thesis "Computational modeling of ion concentration dynamics and metabolic oxygen consumption in brain tissue."
On October 21st, Mikkel Elle Lepperød successfully defended his PhD thesis “Dissecting neuronal circuits for navigation in experiments and models.”
On September 25th, Charlotte Christensen successfully defended her PhD thesis “Balancing stability and plasticity - perturbations of extracellular matrix and inhibitory activity in the mature grid cell network.”
'Seminar on novel probes and AI technology for brain-machine interfaces'
We are excited to announce two seminars on January 16th and the defense of Alessio Buccino on the 17th, all in Bikuben, Kristine Bonnevies' hus, Blindern.
Doctoral candidate Alessio Paolo Buccino at the Department of Informatics, Faculty of Mathematics and Natural Sciences, is defending the thesis“A computationally-assisted approach to neural extracellular electrophysiology with multi-electrode arrays”for the degree of Philosophiae Doctor.
Position as PhD Research Fellow available at the Department of Biosciences.
Gaute Einevoll has started a new podcast called "Vett og vitenskap".
Earlier this year the Research Council of Norway (RCN) announced 270 MNOK for research on digital innovation, of which a CINPLA group has been awarded 16 MNOK for a new project.
Congratulations to four members of CINPLA for their award winning poster presentations this summer, in Norway and in Spain.
We are excited to celebrate three dissertations in the very same day. You are all most welcome to join one day of trial lectures 6th of June, followed by the three defences on the 7th of June.
At 13:00 on Wednesday June 5th, CINPLA will host guest speakers from Universities in France, Norway, Sweden and the USA on the interaction between modelling and experiments in neuroscience.
Almost 50 teams from UiO participated in Norway's largest athletics event - the relay race Holmenkollstafetten. It was a cold day, but great for running and CINPLA finished the 18 450m long course in 1:12:46 as number 160 of the 1553 teams in our category.
PhD candidate Elise Holter Thompson has been granted funding for a three-year postdoc position from the Norwegian Health Association (Nasjonalforeningen for folkehelsen) where she will investigate mechanisms of dementia using an animal model.
"Hjernens visuelle «skysstasjon» er egentlig en portvokter" skrevet av Bjarne Røsjo (3. januar, 2019)
UiO:Life Science awarded our application for internationalization support formalizing a closer collaboration with Arvin Kumar. He will come to Oslo week 50.
For the first time UiO:Lifescience granted undergraduate students with a salary to perform a research project during their summer vacation 2018. CINPLA were lucky to grab 4 talented students in various projects from gene-editing by crisper to behavioral analysis.
"Hjernens balanse mellom læring og hukommelse reguleres av brusk-protein" skrevet av Bjarne Røsjo (5. november, 2018)